{"id":61710,"date":"2024-03-05T14:54:47","date_gmt":"2024-03-05T14:54:47","guid":{"rendered":"https:\/\/medsname.com\/dutas-t\/"},"modified":"2026-05-01T05:31:51","modified_gmt":"2026-05-01T05:31:51","slug":"dutas-t","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nb\/product\/dutas-t\/","title":{"rendered":"Dutas T"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:18px 0;border-radius:4px;\">\n<p style=\"margin:0 0 8px 0;\"><strong>\ud83d\udca1 Raskt svar<\/strong><\/p>\n<p style=\"margin:0;\"><strong>Dutas-T<\/strong> kombinerer <strong>tamsulosin 0,4 mg<\/strong> (an alpha-blocker for immediate urinary symptom relief) with <strong>dutasteride 0.5 mg<\/strong> (a dual 5-alpha-reductase inhibitor that shrinks the prostate over 3\u20136 months). This dual-MOA single-capsule approach is preferred for men with moderate\u2013severe BPH, enlarged prostates (&gt;40 mL), or at risk of acute urinary retention. Once-daily dosing.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Hva du f\u00e5r med MedsBase:<\/strong> WHO-GMP-sertifisert produsent \u00b7 Diskret emballasje \u00b7 Verdensomspennende levering \u00b7 1 400+ verifiserte <a href=\"https:\/\/medsbase.com\/nb\/reviews\/\">kundeanmeldelser<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Hver ordre er dekket av v\u00e5r <a href=\"https:\/\/medsbase.com\/nb\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 hvis pakken din ikke ankommer innen 20 virkedager, sender vi ny.<\/p>\n<h3>Hvorfor bestille fra MedsBase<\/h3>\n<p>V\u00e5re generiske legemidler kommer fra WHO-GMP-sertifiserte produsenter og sendes over hele verden i diskret, n\u00f8ytral emballasje \u2014 ingen legemiddelnavn p\u00e5 utsiden av pakken. Kortbetalinger h\u00e5ndteres av en regulert betalingsbehandler (kontoutskrifter viser en regulert kortbetalingsprosessor \u2014 aldri \u201cMedsBase\u201d eller noe legemiddelnavn). Krypto og SEPA bankoverf\u00f8rsel godtas ogs\u00e5. Hver ordre er dekket av v\u00e5r Reshipment Assurance Policy.<\/p>\n<div style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.95em;\">\n<strong>\ud83d\udd12 Hvorfor bestille fra MedsBase:<\/strong> Verifisert ekte produsentforsyning \u00b7 Diskret verdensomspennende forsendelse \u00b7 Sikker betaling (kredittkort, krypto) \u00b7 Vurdert 4.9\u2605 av 1 400+ kunder\n<\/div>\n<h2><strong>What Is Dutas-T?<\/strong><\/h2>\n<p>Dutas-T is a fixed-dose combination capsule containing <strong>tamsulosin hydrochloride 0.4 mg + dutasteride 0.5 mg<\/strong>. The combination attacks BPH via two complementary mechanisms:<\/p>\n<ul>\n<li><strong>Tamsulosin (alpha-1A blocker):<\/strong> relaxes prostate and bladder-neck smooth muscle \u2014 rapid symptom relief within 1\u20132 weeks<\/li>\n<li><strong>Dutasteride (dual 5-ARI):<\/strong> blocks both type-1 and type-2 5-alpha-reductase enzymes, reducing DHT by ~90% and shrinking the prostate over 3\u20136 months<\/li>\n<\/ul>\n<p>The CombAT (Combination of Avodart and Tamsulosin) trial showed this combination reduced BPH progression, acute urinary retention, and surgery need more than either drug alone. Available strength: <strong>0.4 mg tamsulosin + 0.5 mg dutasteride<\/strong>. Manufactured by Dr. Reddy&#039;s Laboratories.<\/p>\n<h2><strong>Klinisk bruk<\/strong><\/h2>\n<ul>\n<li><strong>Moderate\u2013severe BPH<\/strong> with enlarged prostate (&gt;30\u201340 mL) and moderate\u2013severe LUTS<\/li>\n<li><strong>Men at risk of acute urinary retention<\/strong> or needing BPH-related surgery<\/li>\n<li><strong>Men in whom tamsulosin alone has plateaued<\/strong> after 3\u20136 months and further progression prevention is desired<\/li>\n<\/ul>\n<h2><strong>Hvordan ta<\/strong><\/h2>\n<ol>\n<li>Swallow the capsule whole with water \u2014 do not crush, chew, or open. The inner contents leak onto skin and this risks exposure to women of reproductive age (dutasteride is teratogenic via skin).<\/li>\n<li>Take once daily, roughly 30 minutes after the same meal each day (usually breakfast).<\/li>\n<li>Tamsulosin effect begins within days; the dutasteride effect builds over 3\u20136 months. Peak combination benefit at <strong>6\u201312 months<\/strong>.<\/li>\n<li>Do not skip doses \u2014 dutasteride has a 5-week half-life but tamsulosin effect is daily.<\/li>\n<li>Tell any ophthalmologist before cataract surgery (tamsulosin IFIS risk).<\/li>\n<li>Tell any clinician ordering PSA \u2014 dutasteride halves PSA readings.<\/li>\n<\/ol>\n<h2><strong>Bivirkninger<\/strong><\/h2>\n<p><strong>Tamsulosin-related:<\/strong> dizziness, headache, abnormal ejaculation, rhinitis, asthenia.<\/p>\n<p><strong>Dutasteride-related:<\/strong> decreased libido (~4%), erectile dysfunction (~4%), reduced ejaculate volume, gynecomastia, mood changes.<\/p>\n<p><strong>Alvorlige (sjeldne):<\/strong> orthostatic hypotension, Intraoperative Floppy Iris Syndrome, priapism, persistent sexual side effects after discontinuation (PFS-equivalent).<\/p>\n<h2><strong>Who Should Not Take Dutas-T<\/strong><\/h2>\n<ul>\n<li><strong>Kvinner i fruktbar alder<\/strong> \u2014 dutasteride is teratogenic. Do not handle broken capsules.<\/li>\n<li>Men with severe hepatic impairment (both components hepatically cleared)<\/li>\n<li>Orthostatic hypotension history<\/li>\n<li>Planned cataract \/ glaucoma surgery without telling ophthalmologist<\/li>\n<li>Strong CYP3A4 inhibitor co-therapy (ketoconazole, ritonavir)<\/li>\n<li>Known hypersensitivity to tamsulosin, dutasteride, finasteride, or sulphonamides<\/li>\n<\/ul>\n<h2><strong>Legemiddelinteraksjoner<\/strong><\/h2>\n<ul>\n<li><strong>PDE5-hemmere<\/strong>: tamsulosin + sildenafil\/vardenafil = additive hypotension. Tadalafil 5 mg daily is often the pragmatic choice.<\/li>\n<li><strong>Sterke CYP3A4-hemmere<\/strong>: raise both tamsulosin and dutasteride levels.<\/li>\n<li><strong>Andre alfablokkere<\/strong>: avoid \u2014 additive effect.<\/li>\n<li><strong>PSA-testing<\/strong>: dutasteride halves PSA. Double the measured value for interpretation.<\/li>\n<\/ul>\n<h2><strong>Combination vs Monotherapy<\/strong><\/h2>\n<p>The CombAT trial (4-year outcomes) showed combination therapy reduced BPH clinical progression by ~66% vs dutasteride alone and ~41% vs tamsulosin alone. Combination is preferred when prostate is enlarged (&gt;30\u201340 mL) or PSA is elevated, suggesting ongoing glandular growth. For smaller prostates with pure symptom dominance, tamsulosin monotherapy is often sufficient.<\/p>\n<p>Se ogs\u00e5: <a href=\"https:\/\/medsbase.com\/nb\/urimax-f\/\">Urimax-F<\/a> (tamsulosin + finasteride alternative) and our <a href=\"https:\/\/medsbase.com\/nb\/finasteride-vs-dutasteride\/\">Finasteride vs Dutasteride Guide<\/a>.<\/p>\n<h2><strong>Oppbevaring<\/strong><\/h2>\n<p>Store at room temperature (15\u201330 \u00b0C \/ 59\u201386 \u00b0F), away from moisture and heat. Do not refrigerate. Keep in original blister. Keep away from women of reproductive age.<\/p>\n<h2 id=\"faqs\">Vanlige sp\u00f8rsm\u00e5l<\/h2>\n<h3 class=\"wp-block-heading\">Why the combination pill?<\/h3>\n<p>Tamsulosin and dutasteride attack BPH by different mechanisms \u2014 smooth-muscle relaxation and DHT suppression. Combination therapy reduces BPH progression more than either drug alone (CombAT trial).<\/p>\n<h3 class=\"wp-block-heading\">How soon will symptoms improve?<\/h3>\n<p>Tamsulosin gives urinary symptom relief within 1\u20132 weeks. Dutasteride takes 3\u20136 months for prostate shrinkage. Full combination benefit is seen at 6\u201312 months.<\/p>\n<h3 class=\"wp-block-heading\">Is there a size below which combination is unnecessary?<\/h3>\n<p>For prostates under 30 mL without risk factors, tamsulosin monotherapy often suffices. Combination is strongest for prostates 30 mL and above or men with elevated PSA, bothersome symptoms, and BPH-progression risk factors.<\/p>\n<h3 class=\"wp-block-heading\">What about sexual side effects?<\/h3>\n<p>The dutasteride component contributes decreased libido (~4%) and erectile dysfunction (~4%) risk. The tamsulosin component contributes retrograde ejaculation. Discuss risk-benefit with a clinician, particularly if sexual function is a priority.<\/p>\n<h3 class=\"wp-block-heading\">Can I stop taking Dutas-T abruptly?<\/h3>\n<p>No \u2014 BPH is progressive and symptoms return over weeks to months. Dutasteride has a 5-week half-life, so its effect clears slowly; tamsulosin effect ends within days. For safe discontinuation, discuss with a clinician.<\/p>\n<h3 class=\"wp-block-heading\">Can I combine Dutas-T with a PDE5 inhibitor?<\/h3>\n<p>With care. Tamsulosin + sildenafil\/vardenafil = additive hypotension risk. Tadalafil 5 mg daily is often preferred \u2014 it also treats BPH symptoms on its own.<\/p>\n<h3 class=\"wp-block-heading\">Hva med PSA-overv\u00e5kning?<\/h3>\n<p>Dutasteride halves PSA readings. Always tell your clinician you are on Dutas-T before any PSA test. Convention is to double the measured PSA for interpretation.<\/p>\n<h3 class=\"wp-block-heading\">Will Dutas-T prevent prostate cancer?<\/h3>\n<p>Not directly. The REDUCE trial suggested dutasteride reduced low-grade prostate cancer risk but slightly raised detection of high-grade tumours. Use dutasteride for BPH indications \u2014 not as prostate cancer prophylaxis.<\/p>\n<h3 class=\"wp-block-heading\">Relaterte BPH-produkter<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nb\/urimax\/\">Urimax (Tamsulosin 0,2 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/urimax-capsule\/\">Urimax-kapsel (Tamsulosin 0,4 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/tamsuheal\/\">Tamsuheal (Tamsulosin 0,4 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/monolosin\/\">Monolosin (Tamsulosin 0,4 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/urimax-f\/\">Urimax-F (Tamsulosin + Finasteride)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/nafodil\/\">Nafodil (Naftopidil 50 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/deetor\/\">Deetor (Dutasteride 0,5 mg)<\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.9em;\">\n<p style=\"margin:0;\"><strong>\u2695\ufe0f Medisinsk ansvarsfraskrivelse:<\/strong> Denne informasjonen er utdanningsmessig og erstatter ikke medisinsk r\u00e5dgivning. Konsulter en kliniker f\u00f8r du starter, stopper eller endrer noen medikamenter. Reseptbelagte produkter b\u00f8r kun brukes under medisinsk tilsyn.<\/p>\n<\/div>\n<p data-mb-link-target=\"minoxytop\" data-mb-anchor-variant=\"v2\" style=\"margin-top:1em;font-size:0.95em;color:#444;border-left:3px solid #2c7cb0;padding:0.5em 0.75em;background:#f4f8fb;\"><strong>Se ogs\u00e5:<\/strong> <a href=\"https:\/\/medsbase.com\/nb\/minoxytop\/\"><strong>oral minoxidil (Minoxytop)<\/strong><\/a> \u2014 oral minoxidil for de som ikke responderer p\u00e5 topikal behandling \u2014 Curatio Healthcare 1,25 \/ 2,5 \/ 5 mg tabletter.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Relaterte alternativer<\/h3>\n<p>Andre produkter innen <strong>Menns helse<\/strong> som kunder ogs\u00e5 ser p\u00e5:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nb\/poxet\/\">Poxet<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/zhewitra-oral-jelly\/\">Zhewitra Oral Jelly<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/vidalista-professional\/\">Vidalista Professional<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/filitra-professional\/\">Filitra Professional<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/p-force-fort\/\">P-Force Fort<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Forbedrer urinstr\u00f8m<br \/>\n\u2705 Reduserer prostata st\u00f8rrelse<br \/>\n\u2705 Lindrer urinveisplager<br \/>\n\u2705 Behandler godartet prostatahyperplasi<br \/>\n\u2705 Enhances prostate health<\/p>\n<p>Dutas T contains Tamsulosin and Dutasteride.<\/p>","protected":false},"featured_media":61711,"comment_status":"closed","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3202,3141,3142],"product_tag":[5081,3474,3473],"class_list":{"0":"post-61710","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-benign-prostatic-hyperplasia-bph-treatment","7":"product_cat-category-overview","8":"product_cat-mens-health","9":"product_tag-dutas-t","10":"product_tag-dutasteride","11":"product_tag-tamsulosin","13":"first","14":"instock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product\/61710","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/comments?post=61710"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/media\/61711"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/media?parent=61710"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_brand?post=61710"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_cat?post=61710"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_tag?post=61710"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}