{"id":64815,"date":"2024-10-29T13:55:17","date_gmt":"2024-10-29T13:55:17","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&p=64815"},"modified":"2026-05-10T08:48:12","modified_gmt":"2026-05-10T08:48:12","slug":"niclosig","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nb\/product\/niclosig\/","title":{"rendered":"Niclosig"},"content":{"rendered":"

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Quick Answer — What is Niclosig?<\/h3>\n
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Niclosig<\/strong> is niclosamide 500 mg chewable<\/strong> fra Sigmund Promedia<\/strong>. Niclosamide is the WHO Essential Medicine for intestinal tapeworm<\/strong> (Taenia saginata, Taenia solium intestinal-form, Hymenolepis nana, Diphyllobothrium latum). Standard adult dose: 2 g (4 tablets) as a single dose<\/strong>, chewed thoroughly and swallowed with a small amount of water on an empty stomach.<\/p>\n<\/div>\n<\/div>\n

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Hvorfor bestille fra MedsBase<\/h3>\n

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What is Niclosig?<\/h2>\n

Niclosig<\/strong> is niclosamide 500 mg chewable from Sigmund Promedia<\/strong>. Niclosamide is a salicylanilide-class anthelmintic with a niche but irreplaceable role: it is the cleanest, most reliable single-dose treatment for intestinal cestodes<\/strong> (tapeworms). It is on the WHO Model List of Essential Medicines and has been used continuously since the 1960s.<\/p>\n

Mekanisme for virkning<\/h2>\n

Niclosamide uncouples oxidative phosphorylation<\/strong> in the tapeworm scolex (head). This depletes parasite ATP, paralyses the scolex, and disrupts its grip on the gut wall. The worm is then partially digested by host enzymes — you may see fragmented proglottids in stool rather than an intact worm. Niclosamide is essentially not absorbed from the gut (< 5%), which is therapeutically perfect: high luminal concentration, near-zero systemic exposure.<\/p>\n

Niclosig indications and dose<\/h2>\n\n\n\n\n\n\n\n\n
Indikasjon<\/th>\nDose<\/th>\nDoseringsskjema<\/th>\n<\/tr>\n<\/thead>\n
Beef tapeworm (Taenia saginata)<\/td>\n2 g (4 tablets)<\/td>\nSingle dose, chewed on empty stomach<\/td>\n<\/tr>\n
Pork tapeworm intestinal form (Taenia solium)<\/td>\n2 g (4 tablets)<\/td>\nSingle dose; consider laxative 2 h post-dose to reduce theoretical cysticercosis risk<\/td>\n<\/tr>\n
Fish tapeworm (Diphyllobothrium latum)<\/td>\n2 g (4 tablets)<\/td>\nEnkeltdose<\/td>\n<\/tr>\n
Dwarf tapeworm (Hymenolepis nana)<\/td>\n2 g day 1, then 1 g daily × 6 days<\/td>\n7-day course<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Chew the tablets thoroughly<\/strong>, then swallow with a small amount of water. Take on an empty stomach in the morning, or after a light breakfast. For Taenia solium specifically, some clinicians give a saline laxative 2 h after the dose to evacuate dead proglottids and reduce the (rare) theoretical risk of egg release into the gut and resulting cysticercosis.<\/p>\n

Cysticercosis is a separate disease.<\/strong> Niclosamide treats intestinal<\/em> tapeworm. Neurocysticerkose<\/strong> (Taenia solium larval cysts in the CNS) is treated with albendazole or praziquantel under specialist supervision with imaging and concomitant steroids — not with niclosamide. Headache, seizures, or focal neurological signs in a tapeworm patient need urgent imaging.<\/div>\n

Bivirkninger<\/h2>\n