{"id":66697,"date":"2025-05-01T13:11:44","date_gmt":"2025-05-01T13:11:44","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&#038;p=66697"},"modified":"2026-05-10T08:48:12","modified_gmt":"2026-05-10T08:48:12","slug":"dicaris-adults-tablet","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nb\/product\/dicaris-adults-tablet\/","title":{"rendered":"Dicaris-tabletter for voksne"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"margin:0 0 22px;padding:16px 20px;background:#fff8e1;border-left:4px solid #f5a623;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px;font-size:18px;color:#2c3e50;\">Quick Answer &mdash; What is Dicaris Adults Tablet?<\/h3>\n<div style=\"margin:0;font-size:15px;line-height:1.55;color:#333;\">\n<p><strong>Dicaris-tabletter for voksne<\/strong> is <strong>levamisole 150&nbsp;mg<\/strong> fra <strong>Janssen<\/strong>. Levamisole is both an <strong>anthelmintic<\/strong> (first-line for ascariasis worldwide before albendazole displaced it) and an <strong>immunomodulator<\/strong> used in steroid-dependent or frequently-relapsing nephrotic syndrome to reduce relapse rate. Standard adult anthelmintic dose: <strong>150&nbsp;mg single dose<\/strong>; immunomodulatory dose: 2.5&nbsp;mg\/kg every other day in nephrotic syndrome.<\/p>\n<\/div>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"margin:24px 0;padding:14px 18px;background:#f4f4f4;border:1px solid #e1e1e1;border-radius:4px;font-size:14px;color:#444;line-height:1.55;\"><strong>Hvorfor bestille fra MedsBase:<\/strong> \u2713 Sourced from <strong>WHO-GMP-sertifiserte produsenter<\/strong> \u00b7 \u2713 Diskret emballasje \u00b7 \u2713 Verdensomspennende frakt \u00b7 \u2713 <strong>1,400+ kundeanmeldelser<\/strong> p\u00e5 <a href=\"https:\/\/medsbase.com\/nb\/reviews\/\">medsbase.com\/reviews<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Hver ordre er dekket av v\u00e5r <a href=\"https:\/\/medsbase.com\/nb\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 hvis pakken din ikke ankommer innen 20 virkedager, sender vi ny.<\/p>\n<h3>Hvorfor bestille fra MedsBase<\/h3>\n<p>V\u00e5re generiske legemidler kommer fra WHO-GMP-sertifiserte produsenter og sendes over hele verden i diskret, n\u00f8ytral emballasje \u2014 ingen legemiddelnavn p\u00e5 utsiden av pakken. Kortbetalinger h\u00e5ndteres av en regulert betalingsbehandler (kontoutskrifter viser en regulert kortbetalingsprosessor \u2014 aldri \u201cMedsBase\u201d eller noe legemiddelnavn). Krypto og SEPA bankoverf\u00f8rsel godtas ogs\u00e5. Hver ordre er dekket av v\u00e5r Reshipment Assurance Policy.<\/p>\n<h2 class=\"wp-block-heading\">What is Dicaris Adults Tablet?<\/h2>\n<p><strong>Dicaris-tabletter for voksne<\/strong> inneholder <strong>levamisole 150&nbsp;mg<\/strong> fra <strong>Janssen<\/strong>. Originally developed as a veterinary anthelmintic, levamisole was widely used in human medicine for ascariasis from the 1960s until albendazole and mebendazole displaced it as first-line. It retains an important second indication: <strong>immunomodulation in childhood nephrotic syndrome<\/strong>, where it reduces relapse frequency in steroid-dependent disease and lets clinicians reduce cumulative steroid dose.<\/p>\n<h2 class=\"wp-block-heading\">Mekanisme for virkning<\/h2>\n<p>As an anthelmintic, levamisole is a <strong>nicotinic acetylcholine receptor agonist<\/strong> on parasite muscle, causing spastic paralysis (similar mechanism to pyrantel). The paralysed worm is passed in stool.<\/p>\n<p>As an immunomodulator, levamisole appears to <strong>restore depressed cell-mediated immunity<\/strong> &mdash; it enhances T-cell function, monocyte and macrophage activity, and natural killer cell response. The exact mechanism in nephrotic syndrome remains incompletely understood but the clinical effect (reduced relapse) is well-established in randomised trials.<\/p>\n<h2 class=\"wp-block-heading\">Dicaris Adults Tablet indications and dose<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:14px;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Indikasjon<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Dose<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Doseringsskjema<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Ascariasis (adults)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">150&nbsp;mg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Enkeltdose<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Ascariasis (children)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">2.5&nbsp;mg\/kg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Enkeltdose<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Hookworm (light burden)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">150&nbsp;mg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Single dose, repeat at 7 days if needed<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Steroid-dependent nephrotic syndrome (specialist)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">2.5&nbsp;mg\/kg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Every other day for 12&ndash;24 months under nephrologist supervision<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Take with or after a meal to reduce nausea.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>Specialist supervision for nephrotic syndrome.<\/strong> Long-course levamisole for nephrotic syndrome requires nephrology supervision. Mandatory neutrophil monitoring (FBC every 4&ndash;6 weeks for the first 6 months, then every 3 months) is essential because of the well-described risk of agranulocytosis. Stop immediately at signs of infection or oral ulceration.<\/div>\n<h2 class=\"wp-block-heading\">Bivirkninger<\/h2>\n<ul>\n<li><strong>Common (single-dose):<\/strong> mild nausea, abdominal pain, headache, transient dizziness<\/li>\n<li><strong>Mindre vanlige:<\/strong> rash, fatigue, transient transaminase rise, mild flu-like symptoms<\/li>\n<li><strong>Rare but serious (long-course):<\/strong> agranulocytosis (~3% in long courses, monitoring mandatory), vasculitis with cutaneous necrosis, leukoencephalopathy, hepatitis, Stevens-Johnson syndrome<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Legemiddelinteraksjoner<\/h2>\n<ul>\n<li><strong>Fenytoin<\/strong> &mdash; levamisole increases phenytoin levels; monitor<\/li>\n<li><strong>Warfarin<\/strong> &mdash; potential INR rise; monitor<\/li>\n<li><strong>Alkohol<\/strong> &mdash; rare disulfiram-like reaction; abstain during the treatment course<\/li>\n<li><strong>Steroids<\/strong> &mdash; in nephrotic syndrome, levamisole is added to steroid backbone; the combination is intentional and monitored<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>Graviditet og amming.<\/strong> Albendazol og mebendazol anbefales IKKE i f\u00f8rste trimester (data om teratogenitet fra dyrefors\u00f8k). Bruk er akseptabelt i 2.\/3. trimester ved moderat til tung ormebyrde. Data om ivermectin under graviditet er begrenset, men tilfredsstillende i WHOs massebehandlingsprogrammer; unng\u00e5 i f\u00f8rste trimester der alternativer finnes. Praziquantel og pyrantel er kompatible med graviditet.<\/div>\n<h2 class=\"wp-block-heading\">Kontraindikasjoner<\/h2>\n<ul>\n<li>Hypersensitivity to levamisole or other imidazothiazoles<\/li>\n<li>Pre-existing neutropenia or bone marrow suppression<\/li>\n<li>Alvorlig leversvikt eller nyresvikt<\/li>\n<li>Pregnancy &mdash; first trimester avoidance; long-course immunomodulatory use should not start in pregnancy<\/li>\n<li>Concurrent alcohol use during the treatment window<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Oppbevaring<\/h2>\n<p>Store Dicaris Adults Tablet below 30&deg;C, away from light and moisture.<\/p>\n<h3 class=\"wp-block-heading\">Hvorfor bestille fra MedsBase<\/h3>\n<p>Dicaris Adults Tablet is supplied from a <strong>WHO-GMP-sertifisert produsent<\/strong>, diskr\u00e9 pakket og sendt over hele verden. Hver bestilling er dekket av v\u00e5r <a href=\"https:\/\/medsbase.com\/nb\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance Policy<\/a> \u2014 du tar aldri kostnaden for en tapt pakke.<\/p>\n<h2 id=\"faqs\">Vanlige sp\u00f8rsm\u00e5l<\/h2>\n<h3 class=\"wp-block-heading\">Why is levamisole still used when albendazole exists?<\/h3>\n<p>For routine ascariasis, albendazole has displaced levamisole as first-line because of broader spectrum and equivalent single-dose efficacy. Levamisole&rsquo;s persisting role is in <strong>steroid-dependent or frequently-relapsing nephrotic syndrome<\/strong>, where it reduces relapse rate and steroid burden. It is also used in some veterinary settings.<\/p>\n<h3 class=\"wp-block-heading\">How does Dicaris Adults Tablet treat nephrotic syndrome?<\/h3>\n<p>Levamisole appears to restore cell-mediated immunity, reducing the immunological dysregulation underlying minimal-change nephrotic syndrome. Randomised trials show meaningful reduction in relapse rate at doses around 2.5&nbsp;mg\/kg every other day for 12&ndash;24 months. This is a specialist-supervised therapy with mandatory neutrophil monitoring.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Dicaris Adults Tablet with alcohol?<\/h3>\n<p>Avoid alcohol during the treatment window. A disulfiram-like reaction (flushing, palpitations, nausea) is uncommon but well-documented &mdash; not worth the risk.<\/p>\n<h3 class=\"wp-block-heading\">Will my child take Dicaris Adults Tablet for nephrotic syndrome?<\/h3>\n<p>Long-course levamisole for nephrotic syndrome is dosed by weight (2.5&nbsp;mg\/kg every other day) and requires regular blood testing. The 150&nbsp;mg adult tablet may need to be quartered for paediatric doses; the paediatric tablet (Dicaris Children, 50&nbsp;mg) is purpose-made for this. Consult the nephrology team.<\/p>\n<h3 class=\"wp-block-heading\">What signs should I watch for?<\/h3>\n<p>Stop and seek medical advice immediately for any of: fever, mouth ulcers, sore throat, easy bruising, unexplained tiredness, jaundice, rash with skin breakdown. These can signal agranulocytosis or vasculitis &mdash; serious but reversible if caught early.<\/p>\n<h3 class=\"wp-block-heading\">Is Dicaris Adults Tablet an appetite suppressant?<\/h3>\n<p>No. Some weight loss can occur as a knock-on of severe worm-burden eradication (the parasites were stealing nutrients), but levamisole is not used for weight loss.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Dicaris Adults Tablet during pregnancy?<\/h3>\n<p>Avoid in the first trimester. Single-dose anthelmintic use later in pregnancy is acceptable for moderate-to-heavy worm burden under medical supervision. Long-course immunomodulatory use should not start during pregnancy.<\/p>\n<h3 class=\"wp-block-heading\">How quickly does Dicaris Adults Tablet work for worms?<\/h3>\n<p>Adult worms are paralysed within hours and passed within 24&ndash;72 hours. A single 150&nbsp;mg dose is usually enough for ascariasis. Re-test stool 2&ndash;4 weeks later if symptoms persist.<\/p>\n<h3 class=\"wp-block-heading\">Will Dicaris Adults Tablet treat scabies or ringworm?<\/h3>\n<p>No. Levamisole is for nematodes (especially ascaris) and immunomodulation. Scabies needs ivermectin or permethrin; ringworm is fungal and needs an antifungal (clotrimazole, terbinafine).<\/p>\n<h3 class=\"wp-block-heading\">What is the cocaine adulterant warning about?<\/h3>\n<p>Levamisole was historically used as a cocaine adulterant, which caused agranulocytosis cases in users worldwide. This is a public-health concern about illicit drug supply &mdash; the therapeutic use of levamisole under medical supervision (with monitoring) is well-established and safe.<\/p>\n<p class=\"medsbase-link-boost-2026-05-04\" data-marker=\"mb-link-boost-ivermectin-fenbendazole-combo-pack\"><a href=\"https:\/\/medsbase.com\/nb\/dicaris-adults-tablet\/\">Dicaris-tabletter for voksne<\/a> is levamisole 150 mg, a single-dose anthelmintic with secondary immunomodulator use in nephrotic syndrome; users running a stacked anthelmintic protocol that adds ivermectin and fenbendazole alongside levamisole can pick up the <a href=\"https:\/\/medsbase.com\/nb\/ivermectin-fenbendazole-combo-pack\/\">Ivermectin + Fenbendazole Combo Pack (Iverheal 12 mg + Wormentel 222 mg)<\/a> as the avermectin-benzimidazole add-on.<\/p>\n<p class=\"medsbase-link-boost-2026-05-10\" data-marker=\"mb-link-boost-iverheal\">For patients whose threadworm burden spans multiple species, specialists sometimes combine <a href=\"https:\/\/medsbase.com\/nb\/dicaris-adults-tablet\/\">Dicaris Adults Tablet (levamisole 150 mg)<\/a> med <a href=\"https:\/\/medsbase.com\/nb\/iverheal\/\">Iverheal (ivermectin 3 \/ 6 \/ 12 mg)<\/a> when levamisole alone is insufficient for strongyloidiasis or tissue-migrating larval forms.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Andre antiparasitt\u00e6re legemidler<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nb\/dicaris-adults-tablet\/\">Dicaris Adults Tablet (levamisole 150 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/abd-400-albendazole\/\">ABD 400 (albendazol 400 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/mebex\/\">Mebex (mebendazol 100 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/iverheal\/\">Iverheal (ivermectin)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/nemocid\/\">Nemocid (pyrantelpamoat)<\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:22px 0;border-radius:4px;font-size:14px;color:#444;\"><strong>Medisinsk ansvarsfraskrivelse.<\/strong> Denne siden er kun til informasjonsform\u00e5l og erstatter ikke profesjonell medisinsk r\u00e5dgivning. Snakk med en kvalifisert lege f\u00f8r du starter med noen antihelmintisk behandling, spesielt hvis du er gravid eller ammer, har nedsatt immunforsvar, skal behandle et barn under 2 \u00e5r, eller hvis symptomene vedvarer etter en behandlingsperiode. Eosinofili, vekttap, vedvarende magesmerter eller reiserelaterte symptomer krever klinisk vurdering. Alvorlige parasittiske sykdommer (neurocysticerkose, strongyloides hyperinfeksjon, schistosomiasis med organskade) h\u00e5ndteres av spesialister.<\/div>","protected":false},"excerpt":{"rendered":"<p>Dicaris Adults Tablet (levamisole 150 mg) \u2014 dual-indication anthelmintic and immunomodulator. Single-dose treatment for ascariasis; long-course nephrology use to reduce nephrotic syndrome relapses.<\/p>","protected":false},"featured_media":66703,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3856,3342],"product_tag":[5357,5355,5356],"class_list":{"0":"post-66697","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-threadworm-treatment","7":"product_cat-general-health","8":"product_tag-dicaris","9":"product_tag-dicaris-adults-tablet","10":"product_tag-levamisole","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product\/66697","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/comments?post=66697"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/media\/66703"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/media?parent=66697"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_brand?post=66697"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_cat?post=66697"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_tag?post=66697"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}