{"id":54259,"date":"2023-09-20T09:56:39","date_gmt":"2023-09-20T09:56:39","guid":{"rendered":"https:\/\/medsname.com\/asthafen\/"},"modified":"2026-04-30T10:25:00","modified_gmt":"2026-04-30T10:25:00","slug":"asthafen","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/asthafen\/","title":{"rendered":"Asthafen"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 28px 0;border-radius:4px;\">\n<h3 style=\"margin:0 0 10px 0;font-size:18px;color:#1a1a1a;\">\u26a1 Quick Answer \u2014 What is Asthafen?<\/h3>\n<p><strong>Asthafen<\/strong> bevat <strong>ketotifen<\/strong> \u2014 an oral <strong>mast-cell stabiliser and H1 antihistamine<\/strong>. Used as a long-term preventer for allergic asthma (especially in children), atopic dermatitis flares, and chronic allergic rhinitis. Onset of preventer benefit takes <strong>4\u20138 weeks<\/strong> of consistent twice-daily dosing. Modern asthma guidelines have largely moved away from ketotifen in favour of inhaled corticosteroids (ICS), but it remains useful in young children and in atopic patients with multiple allergic comorbidities. Manufactured by <strong>Cipla<\/strong>; international brand <strong>Zaditen<\/strong>.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Wat u krijgt bij MedsBase:<\/strong> WHO-GMP gecertificeerde fabrikant \u00b7 Discrete verpakking \u00b7 Wereldwijde verzending \u00b7 1.400+ geverifieerde <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">klantbeoordelingen<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n<div style=\"background:#f4f8fb;border:1px solid #e0e0e0;padding:12px 18px;margin:0 0 24px 0;border-radius:4px;font-size:14px;text-align:center;\">\n<strong>\ud83d\udd12 Versleutelde afrekenprocedure<\/strong> \u00b7 <strong>\ud83d\udcb3 Geverifieerde betalingsverwerker<\/strong> \u00b7 <strong>\ud83d\ude9a Wereldwijde verzending<\/strong> \u00b7 <strong>\u2b50 4,9\/5 van 1.400+ klanten<\/strong>\n<\/div>\n<h2>What Is Asthafen?<\/h2>\n<p>Asthafen contains ketotifen 1 mg per tablet (also available as 1 mg\/5 ml syrup). Ketotifen has dual action: it stabilises mast-cell membranes (preventing IgE-driven degranulation and histamine release) and blocks H1 receptors. Internationally sold as Zaditen.<\/p>\n<h2>How Does Ketotifen Work?<\/h2>\n<ul>\n<li><strong>Mast-cell membrane stabilisation<\/strong> \u2014 prevents IgE-mediated release of histamine, leukotrienes, and tryptase.<\/li>\n<li><strong>H1 receptor antagonism<\/strong> \u2014 blocks histamine-mediated itch, sneeze, runny nose, and (mild) bronchoconstriction.<\/li>\n<li><strong>Reduces airway hyperreactivity<\/strong> over 4\u20138 weeks of consistent dosing.<\/li>\n<\/ul>\n<h2>Toepassingen en Indicaties<\/h2>\n<ul>\n<li><strong>Allergic asthma in children<\/strong> \u2014 preventer adjunct (especially when ICS adherence is poor)<\/li>\n<li><strong>Allergic rhinitis<\/strong> \u2014 chronic perennial form<\/li>\n<li><strong>Atopic dermatitis<\/strong> \u2014 adjunct<\/li>\n<li><strong>Chronic urticaria<\/strong> \u2014 alternative to second-generation antihistamine<\/li>\n<li><strong>Allergische conjunctivitis<\/strong><\/li>\n<\/ul>\n<h2>Asthafen Dosage<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Pati\u00ebnt<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Dosering<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Frequentie<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Adults &amp; children &gt;3 yr<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>1 mg<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Twice daily with food<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Children 6 mo \u2013 3 yr<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>0.5 mg<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Twice daily with food<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Sedation-prone patients<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Start at 0.5 mg evening dose<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Titrate up over 1 week<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Side Effects of Asthafen<\/h2>\n<ul>\n<li>Drowsiness (commonest \u2014 usually settles within 1\u20132 weeks)<\/li>\n<li>Mild weight gain (appetite stimulation)<\/li>\n<li>Droge mond<\/li>\n<li>Duizeligheid<\/li>\n<li>Hoofdpijn<\/li>\n<\/ul>\n<p><strong>Ernstig \u2014 stop en zoek hulp:<\/strong><\/p>\n<ul>\n<li>Ernstige allergische reactie<\/li>\n<li>Severe drowsiness preventing daily function<\/li>\n<li>Mood change, agitation in children<\/li>\n<\/ul>\n<h2>Waarschuwingen en voorzorgsmaatregelen<\/h2>\n<ul>\n<li><strong>Drowsiness:<\/strong> avoid driving or operating machinery until you know how it affects you.<\/li>\n<li><strong>Not a rescue medication.<\/strong> Use SABA (Asthalin, Levolin) for acute bronchospasm.<\/li>\n<li><strong>Continue ICS<\/strong> if previously prescribed; ketotifen does not replace inhaled corticosteroids.<\/li>\n<li><strong>Slow onset:<\/strong> 4\u20138 weeks of consistent dosing required for full effect.<\/li>\n<li><strong>Zwangerschap en borstvoeding:<\/strong> use only when benefits outweigh risks; second-generation antihistamines (loratadine, levocetirizine) preferred.<\/li>\n<\/ul>\n<h2>Contra-indicaties<\/h2>\n<ul>\n<li>Hypersensitivity to ketotifen<\/li>\n<li>Concomitant oral antidiabetics (rare reports of reversible thrombocytopenia in combination)<\/li>\n<\/ul>\n<h2>Geneesmiddelinteracties<\/h2>\n<ul>\n<li>Sedatives, alcohol, hypnotics \u2014 additive sedation<\/li>\n<li>Oral antidiabetics \u2014 reversible thrombocytopenia (rare)<\/li>\n<li>CNS depressants \u2014 additive sedation<\/li>\n<\/ul>\n<h2>Opslag<\/h2>\n<ul>\n<li>Bewaren beneden <strong>25\u00b0C<\/strong> in a cool, dry place away from direct sunlight.<\/li>\n<li>Keep in original packaging until use to protect from moisture and light.<\/li>\n<li>Do not use after the expiry date printed on the strip.<\/li>\n<li>Buiten bereik van kinderen houden.<\/li>\n<\/ul>\n<h2>Gerelateerde alternatieven op MedsBase<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/asthalin-inhaler\/\"><strong>Asthalin Inhaler \u2014 salbutamol verlichter<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/budecort-inhaler\/\"><strong>Budecort Inhaler \u2014 budesonide ICS-preventer<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/foracort-inhaler\/\"><strong>Foracort Inhaler \u2014 budesonide + formoterol ICS-LABA<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/montair\/\"><strong>Montair \u2014 montelukast LTRA-tablet<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/tiova-inhaler\/\"><strong>Tiova Inhaler \u2014 tiotropium LAMA voor COPD<\/strong><\/a><\/li>\n<\/ul>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3>How is ketotifen different from cetirizine or loratadine?<\/h3>\n<p>Ketotifen has dual action (mast-cell stabilisation + H1 block) and longer-term preventer effect on allergic disease. Modern second-generation antihistamines (loratadine, cetirizine, levocetirizine) are non-sedating but lack the mast-cell stabilisation. For acute allergy: a non-sedating antihistamine. For chronic preventer effect in allergic asthma\/rhinitis: ketotifen.<\/p>\n<h3>Why is ketotifen still used in children?<\/h3>\n<p>It is well-tolerated, available as a syrup, and the mild sedation can be helpful with bedtime dosing in atopic children with sleep disturbance from itch.<\/p>\n<h3>Will Asthafen replace my inhaler?<\/h3>\n<p>No \u2014 it is an add-on preventer, not a replacement for ICS or reliever therapy.<\/p>\n<h3>Hoelang duurt het voordat ik verbetering merk?<\/h3>\n<p>4\u20138 weeks for full preventer effect on asthma and rhinitis. Antihistamine effect (itch, sneeze) starts within hours.<\/p>\n<h3>Is Asthafen safe in pregnancy?<\/h3>\n<p>Limited data; generally avoided in favour of better-studied second-generation antihistamines.<\/p>\n<h3>Can I drink alcohol on Asthafen?<\/h3>\n<p>Alcohol amplifies the drowsiness \u2014 avoid or minimise.<\/p>\n<h3>How long can children take Asthafen?<\/h3>\n<p>Indefinite use is acceptable while symptoms persist; reassess every 6\u201312 months.<\/p>\n<h3>Why must I take it with food?<\/h3>\n<p>Reduces stomach upset; bioavailability is unaffected.<\/p>\n<h3>Can I stop Asthafen suddenly?<\/h3>\n<p>No taper needed for ketotifen specifically, but allergic symptoms will return \u2014 discuss long-term plan with your prescriber.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:24px 0;border-radius:4px;font-size:13px;\"><strong>Medische disclaimer:<\/strong> Deze pagina is educatief en vervangt geen professioneel medisch advies. Raadpleeg altijd een gekwalificeerde zorgverlener voordat u een inhaler of respiratoir medicijn start, stopt of wijzigt, vooral als u andere medische aandoeningen heeft, andere voorgeschreven medicijnen gebruikt, zwanger bent of borstvoeding geeft, of ouder bent dan 65.<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Gerelateerde alternatieven<\/h3>\n<p>Andere producten in <strong>Chronische aandoeningen<\/strong> die klanten ook bekijken:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/glycomet-sr\/\">Glycomet SR<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/leptomate\/\">Leptomate<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/listril-plus\/\">Listril Plus<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/loratin\/\">Loratin<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/ondrea\/\">Ondrea<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<h5>\u2705 Allergy symptom relief<br \/>\n\u2705 Non-drowsy formula<br \/>\n\u2705 Rapid symptom control<br \/>\n\u2705 Enhanced comfort<\/h5>\n<p><span style=\"color: #999999;\">Contains Ketotifen Fumarate<\/span><\/p>","protected":false},"featured_media":54260,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3681,3141,3223],"product_tag":[3697,3698],"class_list":{"0":"post-54259","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-asthma-copd-treatment","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","9":"product_tag-asthafen-1-mg","10":"product_tag-ketotifen-fumarate","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/54259","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=54259"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/54260"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=54259"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=54259"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=54259"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=54259"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}