{"id":54802,"date":"2023-09-20T10:05:10","date_gmt":"2023-09-20T10:05:10","guid":{"rendered":"https:\/\/medsname.com\/retino-ac-gel\/"},"modified":"2026-04-30T10:24:53","modified_gmt":"2026-04-30T10:24:53","slug":"retino-ac-gel","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/retino-ac-gel\/","title":{"rendered":"Retino Ac Gel"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:20px 0;border-radius:6px;\">\n<h3 style=\"margin:0 0 10px 0;font-size:1.15em;\">\ud83d\udca1 Quick Answer \u2014 What is Retino AC Gel?<\/h3>\n<p style=\"margin:0;\"><strong>Retino AC Gel<\/strong> contains clindamycin phosphate 1% + tretinoin 0.025% \u2014 a topical combination of an antibiotic and a retinoid for moderate-to-severe inflammatory acne vulgaris. Apply a thin layer once daily at night to clean dry skin. Avoid eyes, lips, and corners of the nose. SPF 30+ daily. Combination therapy is more effective than either agent alone but more irritating; introduce gradually.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 18px;margin:18px 0;border-radius:6px;font-size:0.95em;\">\n<strong>\ud83c\udfed WHO-GMP gecertificeerde fabrikant<\/strong> \u00b7 <strong>\ud83d\udce6 Discrete verpakking<\/strong> (gewone envelop) \u00b7 <strong>\ud83c\udf0d Wereldwijde verzending<\/strong> met <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance<\/strong><\/a> \u00b7 <strong>\u2b50 1.400+ klanten<\/strong> \u2014 <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">lees beoordelingen<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n<h3 class=\"wp-block-heading\">Waarom bestellen bij MedsBase<\/h3>\n<p>Choosing Retino AC Gel from MedsBase:<\/p>\n<ul>\n<li><strong>WHO-GMP gecertificeerde fabrikant<\/strong> \u2014 afkomstig uit een gereguleerde faciliteit, complete verpakking met batchnummer en vervaldatum.<\/li>\n<li><strong>Discrete verpakking<\/strong> \u2014 gewone envelop, geen medicatienaam aan de buitenkant.<\/li>\n<li><strong>Wereldwijde verzending<\/strong> met <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het kosteloos opnieuw (onder voorbehoud van beleidstermen).<\/li>\n<li><strong>Loyaliteitspunten<\/strong> \u2014 1 punt per $1 uitgegeven (peptiden uitgesloten); 100 punten = $5 korting.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">What Retino AC Gel is and how it works<\/h2>\n<p>Retino AC Gel contains <strong>clindamycin phosphate 1% + tretinoin 0.025%<\/strong>. Clindamycin is a lincosamide antibiotic that targets <em>Cutibacterium acnes<\/em> (formerly P. acnes) by binding the bacterial 50S ribosome and blocking protein synthesis. Tretinoin is a retinoid that normalises follicular keratinisation, reduces sebum, and accelerates comedone clearance. Combining the two gives faster and more complete clearance of inflammatory acne lesions than either agent alone, while the steric configuration of the gel formulation prevents tretinoin from oxidising the clindamycin. Manufacturer: Johnson &amp; Johnson \/ Janssen (WHO-GMP certified).<\/p>\n<h2 class=\"wp-block-heading\">Indicaties<\/h2>\n<ul>\n<li><strong>Moderate-to-severe inflammatory acne vulgaris<\/strong> \u2014 papules, pustules, and nodules with comedonal background.<\/li>\n<li><strong>Mixed comedonal-inflammatory acne<\/strong> where the dual mechanism shortens treatment time.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Hoe aan te vragen<\/h2>\n<ul>\n<li>Cleanse with a gentle non-foaming cleanser; pat dry; wait 10\u201315 minutes (apply on damp skin amplifies irritation).<\/li>\n<li>Apply a pea-sized amount once daily at night to entire affected area, not just spots.<\/li>\n<li>Acclimation: alternate nights for 2 weeks if irritation is significant.<\/li>\n<li>Avoid eyes, lips, mouth corners, and nasal corners (>5 mm clearance).<\/li>\n<li>Mandatory SPF 30+ broad-spectrum daily.<\/li>\n<li>Continue for at least 8\u201312 weeks before judging response.<\/li>\n<\/ul>\n<div style=\"background:#eef7ee;border-left:4px solid #4caf50;padding:16px 20px;margin:22px 0;border-radius:6px;\">\n<p style=\"margin:0;\"><strong>\u2713 Antibiotic stewardship<\/strong> \u2014 Topical clindamycin monotherapy drives <em>C. acnes<\/em> resistance. Combination with tretinoin (or with benzoyl peroxide) reduces resistance development. Limit clindamycin courses to 12 weeks where possible; switch to non-antibiotic maintenance (tretinoin alone, adapalene, BPO) after acne control is established.<\/p>\n<\/div>\n<h2 class=\"wp-block-heading\">Bijwerkingen<\/h2>\n<ul>\n<li><strong>Vaak voorkomend:<\/strong> dryness, peeling, mild burning, transient acne flare in weeks 2\u20134 (purge), photosensitivity.<\/li>\n<li><strong>Minder vaak:<\/strong> contact dermatitis, perioral dermatitis if applied close to mouth, mild gastrointestinal upset (rare from topical absorption).<\/li>\n<li><strong>Zeldzaam:<\/strong> pseudomembranous colitis from systemic clindamycin absorption (very rare with topical use), severe contact allergy.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Contra-indicaties<\/h2>\n<ul>\n<li>Pregnancy (Category C\/X for tretinoin component) and breastfeeding.<\/li>\n<li>History of inflammatory bowel disease (clindamycin contraindication).<\/li>\n<li>Eczema, severe sunburn, broken skin at application site.<\/li>\n<li>Known hypersensitivity to clindamycin, lincosamides, or retinoids.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Geneesmiddelinteracties<\/h2>\n<p>Avoid concurrent strong topical agents (BPO at the same application \u2014 apply at separate times of day; salicylic acid; alpha hydroxy acids). Topical clindamycin has additive risk if combined with neuromuscular blockers (theoretical, with significant systemic absorption only). Avoid concurrent erythromycin (cross-resistance and antagonism in some strains).<\/p>\n<h2 class=\"wp-block-heading\">Opslag<\/h2>\n<p>Bewaren onder 25 \u00b0C, uit direct licht. Houd de tube goed gesloten.<\/p>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3 class=\"wp-block-heading\">Hoelang duurt het voordat ik resultaten zie?<\/h3>\n<p>Inflammatory lesions typically reduce by 30\u201350% at 4\u20136 weeks, with full effect by 12 weeks. If no improvement at 12 weeks, escalate to oral antibiotics, oral isotretinoin (severe cases), or hormonal therapy under specialist guidance.<\/p>\n<h3 class=\"wp-block-heading\">Why does Retino AC Gel include both an antibiotic and a retinoid?<\/h3>\n<p>The two attack different parts of the acne pathway \u2014 clindamycin kills <em>C. acnes<\/em> bacteria in pores; tretinoin normalises pore-blocking dead skin and reduces sebum. The combination is more effective than monotherapy, and the retinoid component reduces antibiotic resistance development.<\/p>\n<h3 class=\"wp-block-heading\">Is Retino AC Gel safe in pregnancy?<\/h3>\n<p>No \u2014 the tretinoin component is teratogenic (Category C\/X). Use effective contraception throughout treatment; stop before conception.<\/p>\n<h3 class=\"wp-block-heading\">Can I use Retino AC Gel with benzoyl peroxide?<\/h3>\n<p>Yes, at separate times \u2014 BPO in the morning, Retino AC Gel at night. BPO further reduces antibiotic resistance and treats inflammatory lesions independently.<\/p>\n<h3 class=\"wp-block-heading\">Why is my skin getting worse after 2 weeks?<\/h3>\n<p>Retinoid purge \u2014 pre-existing micro-comedones surfacing as visible lesions. Resolves by week 4\u20136 with continued use. Add a non-comedogenic moisturiser; do not stop unless severe.<\/p>\n<h3 class=\"wp-block-heading\">Can I shave the affected area?<\/h3>\n<p>Yes, but use a sharp blade with mild shaving cream and rinse with cool water. Allow tretinoin to fully absorb (2 hours) before shaving. Stop tretinoin 24 hours before any waxing.<\/p>\n<h3 class=\"wp-block-heading\">Can I use Retino AC Gel on the chest and back?<\/h3>\n<p>Yes \u2014 if your acne involves trunk, use a thin layer; this is sometimes called &#8220;chest and back&#8221; or &#8220;torso&#8221; acne and the same protocol applies.<\/p>\n<h3 class=\"wp-block-heading\">Is it normal for my skin to feel waxy\/sticky?<\/h3>\n<p>A slight residue is normal in the first hour after application and absorbs fully by morning. If persistent, you may be applying too much \u2014 reduce to a smaller pea-sized amount.<\/p>\n<h3 class=\"wp-block-heading\">Should I use Retino AC Gel if I have only mild comedonal acne?<\/h3>\n<p>Probably not \u2014 for purely comedonal acne (blackheads\/whiteheads only, no inflammation), topical retinoid alone (Retino-A, A-Ret, Tretin) is preferred to avoid unnecessary antibiotic exposure.<\/p>\n<h3 class=\"wp-block-heading\">How does it compare with topical adapalene + BPO?<\/h3>\n<p>Adapalene + BPO is a non-antibiotic alternative with similar efficacy and lower resistance risk; it is now first-line for inflammatory acne in most guidelines. Retino AC Gel is reserved when adapalene is unavailable or BPO is poorly tolerated.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Andere Schoonheids- &amp; Huidverzorgingsmedicijnen<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/melalite-forte-cream\/\"><strong>Melalite Forte Cr\u00e8me \u2014 hydroquinon 4% voor melasma<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/retino-a-cream\/\"><strong>Retino-A Cr\u00e8me \u2014 tretino\u00efne voor acne en veroudering<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/melacare-cream\/\"><strong>Melacare Cr\u00e8me \u2014 Kligman triple voor melasma<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/permite-cream\/\"><strong>Permite Cr\u00e8me \u2014 permethrin 5% voor schurft<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/tenovate-cream\/\"><strong>Tenovate Cr\u00e8me \u2014 clobetasol 0,05% voor ernstige ontstekingen<\/strong><\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:24px 0;border-radius:6px;font-size:0.95em;\">\n<p style=\"margin:0;\"><strong>Medisch disclaimer.<\/strong> Deze inhoud is voor algemene informatie over het product en is geen medisch advies of een vervanging voor advies van een gekwalificeerde zorgprofessional. Gebruik elke actuele of orale medicatie alleen onder passend medisch toezicht; misbruik kan ernstige schade veroorzaken.<\/p>\n<\/div>\n<p><!-- medsbase-guide-tretinoin --><\/p>\n<p style=\"margin:20px 0 0;padding:12px 16px;background:#f4f8fb;border-left:3px solid #2c7cb0;border-radius:3px;font-size:14px\">\ud83d\udcda <strong>Meer informatie:<\/strong> <a href=\"https:\/\/medsbase.com\/nl\/buy-tretinoin-online\/\">Hoe Tretinoine Online te Kopen Zonder Recept (2026 Gids)<\/a><\/p>","protected":false},"excerpt":{"rendered":"<h5>\u2705 Vermindert huidontsteking<br \/>\n\u2705 Prevents new acne formation<br \/>\n\u2705 Controls bacterial growth<br \/>\n\u2705 Promotes dead skin shedding<br \/>\n\u2705 Verbeterd het uiterlijk van de huid<\/h5>\n<p><span style=\"color: #999999;\">Retino Ac Gel contains Clindamycin &amp; <a title=\"Comparing Tretinoin and Retinol: Unveiling the Distinctions between Two Retinoids\" href=\"https:\/\/medsbase.com\/nl\/tretinoin-vs-retinol-the-two-retinoids-compared\/\">Tretinoin<\/a><\/span><\/p>","protected":false},"featured_media":54803,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3215,3642,3141,3223,3342],"product_tag":[3785,3786,3648],"class_list":{"0":"post-54802","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-acne-treatment","7":"product_cat-beauty-skin-care","8":"product_cat-category-overview","9":"product_cat-chronic-conditions","10":"product_cat-general-health","11":"product_tag-clindamycin","12":"product_tag-retino-ac-gel","13":"product_tag-tretinoin","15":"first","16":"outofstock","17":"shipping-taxable","18":"purchasable","19":"product-type-variable","20":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/54802","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=54802"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/54803"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=54802"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=54802"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=54802"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=54802"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}