{"id":54862,"date":"2023-09-20T10:06:04","date_gmt":"2023-09-20T10:06:04","guid":{"rendered":"https:\/\/medsname.com\/clomiford\/"},"modified":"2026-05-01T06:37:00","modified_gmt":"2026-05-01T06:37:00","slug":"clomiford","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/clomiford\/","title":{"rendered":"Clomiford"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:18px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin-top:0;color:#8a5a00;\">Quick Answer \u2014 What is Clomiford?<\/h3>\n<p style=\"margin:0;font-size:15px;line-height:1.6;\"><strong>Clomiford<\/strong> bevat <strong>clomiphene citrate<\/strong> &mdash; a selective oestrogen receptor modulator (SERM) used as the first-line oral medication for ovulation induction in women, and widely used off-label in men for hypogonadism, post-cycle therapy after anabolic-androgenic steroids (AAS), and recovery from testosterone replacement therapy (TRT). Manufactured by Sun Pharma and supplied in <strong>three strengths &mdash; 25 mg, 50 mg and 100 mg tablets<\/strong> &mdash; allowing flexible dose titration that single-strength clomiphene products do not. <strong>Female ovulation induction:<\/strong> 50 mg once daily for 5 days starting cycle day 2-5; if no ovulation, increase by 50 mg in subsequent cycles up to 150 mg\/day. Maximum 6 ovulatory cycles. <strong>Male hypogonadism (off-label):<\/strong> 25-50 mg every other day or daily, titrated to a target serum total testosterone, for several months. <strong>Specialist-supervised worldwide.<\/strong> Multiple-pregnancy rate ~8-10% (mostly twins). Visual disturbances are uncommon (1-2%) but require immediate discontinuation if they occur.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Wat u krijgt bij MedsBase:<\/strong> WHO-GMP gecertificeerde fabrikant \u00b7 Discrete verpakking \u00b7 Wereldwijde verzending \u00b7 1.400+ geverifieerde <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">klantbeoordelingen<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n<div style=\"background:#f4f8fb;border:1px solid #d6e4ec;padding:12px 18px;margin:14px 0;border-radius:4px;font-size:14px;color:#3a5160;text-align:center;\">\n<strong>\ud83d\udd12 Versleutelde Afrekenprocedure<\/strong> \u00b7 <strong>\ud83d\udcb3 Geverifieerde Betaalprocessor<\/strong> \u00b7 <strong>\ud83d\ude9a Wereldwijde Verzending<\/strong> \u00b7 <strong>\u2b50 4.9\/5 van 1.400+ klanten<\/strong>\n<\/div>\n<div style=\"background:#fafafa;border:1px solid #e0e0e0;padding:16px 20px;margin:18px 0;border-radius:4px;\">\n<strong style=\"display:block;margin-bottom:8px;color:#333;\">Op deze pagina<\/strong><\/p>\n<ul style=\"margin:0;padding-left:20px;line-height:1.8;\">\n<li><a href=\"#what-is\">What is Clomiford?<\/a><\/li>\n<li><a href=\"#strengths\">Why three strengths matter<\/a><\/li>\n<li><a href=\"#how-it-works\">How clomiphene works<\/a><\/li>\n<li><a href=\"#uses\">Approved &amp; off-label uses<\/a><\/li>\n<li><a href=\"#how-to-take-women\">Dosing for ovulation induction (women)<\/a><\/li>\n<li><a href=\"#how-to-take-men\">Dosing for male hypogonadism &amp; PCT (off-label)<\/a><\/li>\n<li><a href=\"#side-effects\">Bijwerkingen &amp; veiligheid<\/a><\/li>\n<li><a href=\"#visual\">Visual disturbances &mdash; STOP and seek review<\/a><\/li>\n<li><a href=\"#contraindications\">Contra-indicaties &amp; waarschuwingen<\/a><\/li>\n<li><a href=\"#interactions\">Geneesmiddelinteracties<\/a><\/li>\n<li><a href=\"#comparisons\">How Clomiford compares to alternatives<\/a><\/li>\n<li><a href=\"#storage\">Opslag &amp; houdbaarheid<\/a><\/li>\n<li><a href=\"#faq\">Veelgestelde vragen<\/a><\/li>\n<\/ul>\n<\/div>\n<h2 id=\"what-is\" class=\"wp-block-heading\">What is Clomiford?<\/h2>\n<p>Clomiford is a brand of <strong>clomiphene citrate<\/strong> manufactured by Sun Pharma, supplied as oral tablets in three strengths: <strong>25 mg, 50 mg and 100 mg<\/strong>. Pack sizes available at MedsBase: <strong>30, 60, 90, 200, 400 or 800 tablets<\/strong>.<\/p>\n<p>Clomiphene citrate is a <strong>selective oestrogen receptor modulator (SERM)<\/strong> in the same drug class as tamoxifen. It is sold internationally under brand names including <strong>Clomid (Sanofi-Aventis), Serophene (Merck Serono), Milophene, Fertomid, Klomen, Pergotime<\/strong>, and many generic versions. Clomiford is also a sister product to <a href=\"https:\/\/medsbase.com\/nl\/clomisign\/\"><strong>Clomisign (Cipla, single strength 50 mg)<\/strong><\/a> on this site &mdash; both contain identical active ingredient at equivalent doses.<\/p>\n<h2 id=\"strengths\" class=\"wp-block-heading\">Why three strengths matter<\/h2>\n<p>Most clomiphene products are single-strength 50 mg, which forces patients to split tablets for sub-50 mg doses (imprecise) or to take multiple tablets for higher doses (wasteful). The 25 \/ 50 \/ 100 mg ladder of Clomiford allows precise dosing without splitting:<\/p>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Sterkte<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Beste voor<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>25 mg<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Male hypogonadism micro-dosing (12.5-25 mg every other day or daily); women very sensitive to clomiphene side effects; mid-cycle dose tapers<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>50 mg<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Standard female ovulation-induction starting dose; standard male PCT dose<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>100 mg<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Female second-cycle dose escalation; aggressive PCT regimens (clomiphene 100 mg\/day for the first 2 weeks); higher male doses for severe hypogonadism<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Pack sizes from 30 to 800 tablets reflect the wide range of clinical use cases &mdash; a single female fertility cycle requires only 5-15 tablets, but male long-term hypogonadism therapy can require 100+ tablets per quarter, and PCT protocols often use 60+ tablets over a single 6-week cycle.<\/p>\n<h2 id=\"how-it-works\" class=\"wp-block-heading\">How clomiphene works<\/h2>\n<p>Clomiphene citrate is a <strong>mixed agonist\/antagonist at oestrogen receptors<\/strong>. Its principal site of action is the <strong>hypothalamus<\/strong>, where it blocks the negative-feedback signal that circulating oestradiol normally exerts on GnRH neurones. The hypothalamus &#8220;thinks&#8221; oestrogen is low, so it increases GnRH pulse frequency. Increased GnRH drives the pituitary to release more <strong>LH and FSH<\/strong>, which in turn stimulate:<\/p>\n<ul>\n<li><strong>In women:<\/strong> ovarian follicular development, dominant-follicle selection, and (with the LH surge that follows) ovulation<\/li>\n<li><strong>In men:<\/strong> Leydig cell testosterone production, Sertoli cell support of spermatogenesis<\/li>\n<\/ul>\n<p>Because clomiphene works upstream at the hypothalamic-pituitary level rather than replacing oestrogen or testosterone directly, it preserves the body&#8217;s natural endocrine axis &mdash; which is why it is preferred over testosterone replacement therapy in younger men with secondary hypogonadism who wish to maintain fertility.<\/p>\n<p>Clomiphene is a racemic mixture of two isomers: <strong>enclomiphene<\/strong> (anti-oestrogenic, the desired effect) and <strong>zuclomiphene<\/strong> (more oestrogenic, longer half-life). Most of the desired LH\/FSH-stimulating effect comes from enclomiphene; zuclomiphene&#8217;s 5-7 day half-life means it accumulates with repeated dosing, contributing to oestrogenic side effects including hostile cervical mucus and thin endometrium that sometimes limit effectiveness in long courses.<\/p>\n<h2 id=\"uses\" class=\"wp-block-heading\">Approved &amp; off-label uses<\/h2>\n<p><strong>Licensed indications (women):<\/strong><\/p>\n<ul>\n<li><strong>Ovulation induction<\/strong> in anovulatory infertility &mdash; primarily polycystic ovary syndrome (PCOS), which accounts for ~70% of clomiphene prescriptions globally<\/li>\n<li><strong>Hypothalamic dysfunction<\/strong> (group I or II WHO ovulation disorders) where there is some intact hypothalamic-pituitary axis<\/li>\n<li><strong>Luteal-phase defect<\/strong> \u2014 geselecteerde gevallen<\/li>\n<li><strong>Unexplained infertility<\/strong> &mdash; sometimes used with intrauterine insemination (IUI)<\/li>\n<\/ul>\n<p><strong>Off-label but well-established uses (men):<\/strong><\/p>\n<ul>\n<li><strong>Secondary hypogonadism<\/strong> &mdash; particularly in younger men with low testosterone who want to preserve fertility. Clomiphene maintains the HPG axis intact, unlike exogenous testosterone which suppresses it.<\/li>\n<li><strong>Idiopathic male infertility<\/strong> &mdash; with normal-or-low LH\/FSH and normal-or-low testosterone<\/li>\n<li><strong>Post-cycle therapy (PCT)<\/strong> after AAS use &mdash; restarts the HPG axis after AAS-induced suppression<\/li>\n<li><strong>Recovery from TRT<\/strong> for men who wish to come off testosterone replacement and restore endogenous production<\/li>\n<li><strong>Oligozoospermia<\/strong> with hormonal imbalance<\/li>\n<\/ul>\n<h2 id=\"how-to-take-women\" class=\"wp-block-heading\">Dosing for ovulation induction (women)<\/h2>\n<p>Clomiphene cycles must be supervised by a fertility specialist or experienced gynaecologist with access to ultrasound monitoring.<\/p>\n<ol>\n<li><strong>Start dose: 50 mg once daily for 5 consecutive days<\/strong>, beginning on cycle day 2, 3, 4 or 5<\/li>\n<li>Take at the same time each day, with or without food<\/li>\n<li>Ovulation typically occurs <strong>5-12 days after the last clomiphene tablet<\/strong>, on average around cycle day 14-16<\/li>\n<li>Confirm ovulation by ultrasound follicular tracking, mid-luteal progesterone (day 21), home LH-surge kits, or basal body temperature charts<\/li>\n<li>Time intercourse, IUI, or hCG ovulation trigger accordingly<\/li>\n<li>If no ovulation in the first cycle, increase to <strong>100 mg\/day for 5 days<\/strong>, vervolgens in <strong>150 mg\/day for 5 days<\/strong> if still anovulatory<\/li>\n<li><strong>Maximum 6 ovulatory cycles<\/strong> &mdash; after that, the cumulative pregnancy benefit plateaus and the recommendation is to switch to letrozole, gonadotropins, or assisted reproduction<\/li>\n<li><strong>Maximum dose 150 mg\/day<\/strong> &mdash; doses above this provide little additional benefit and are not licensed<\/li>\n<\/ol>\n<p>Approximately 70-80% of women will ovulate on clomiphene; the cumulative pregnancy rate over 6 ovulatory cycles is ~50-60% in well-selected PCOS populations.<\/p>\n<p>Women particularly sensitive to side effects (mood symptoms, hot flushes) sometimes do better on a <strong>25 mg starting dose for 5 days<\/strong> &mdash; the 25 mg tablet of Clomiford allows this without splitting. Discuss with your fertility specialist whether a lower starting dose is appropriate for your situation.<\/p>\n<h2 id=\"how-to-take-men\" class=\"wp-block-heading\">Dosing for male hypogonadism &amp; PCT (off-label)<\/h2>\n<p>Male protocols vary by indication and prescriber. Common regimens:<\/p>\n<ul>\n<li><strong>Secondary hypogonadism, fertility-preserving:<\/strong> 25-50 mg every other day or 12.5-25 mg daily, titrated to a target serum total testosterone of ~600 ng\/dL (20 nmol\/L). The 25 mg tablet of Clomiford avoids splitting for these sub-50 mg micro-doses.<\/li>\n<li><strong>Post-cycle therapy after AAS:<\/strong> common protocols use <strong>100 mg\/day for the first 2 weeks<\/strong> (using the 100 mg tablet) followed by <strong>50 mg\/day for weeks 3-4<\/strong> en <strong>25 mg\/day for week 5-6<\/strong> &mdash; a stepped taper. Often combined with hCG (Eutrig HP, HUCOG) for the first 2-4 weeks to re-prime the testes, and sometimes with tamoxifen 20 mg\/day.<\/li>\n<li><strong>Recovery from TRT:<\/strong> often a 2-4 week hCG bridge first (1,500-3,000 IU SC every other day), then clomiphene 25-50 mg every other day for several months. Bloodwork at 6 weeks to titrate.<\/li>\n<li><strong>Idiopathic oligozoospermia with low-normal LH\/FSH:<\/strong> 25-50 mg\/day for 3-6 months, with semen analysis at 3 and 6 months<\/li>\n<\/ul>\n<p>Men taking clomiphene should have baseline testosterone, oestradiol, LH, FSH, SHBG, prolactin, full blood count, and liver function. Repeat at 6-12 weeks to titrate dose. Some men experience marked oestradiol elevation on clomiphene (because increased testosterone aromatises to oestradiol) &mdash; an aromatase inhibitor (anastrozole 0.25-0.5 mg twice weekly) is sometimes co-prescribed when oestradiol exceeds 40 pg\/mL or when clinical symptoms (gynaecomastia, water retention, mood changes) appear.<\/p>\n<h2 id=\"side-effects\" class=\"wp-block-heading\">Bijwerkingen &amp; veiligheid<\/h2>\n<p><strong>Vaak (1 op de 10):<\/strong><\/p>\n<ul>\n<li>Hot flushes (the classic &#8220;anti-oestrogen&#8221; symptom)<\/li>\n<li>Mood changes &mdash; irritability, low mood, anxiety; usually mild and reversible<\/li>\n<li>Hoofdpijn<\/li>\n<li>Nausea, mild abdominal discomfort<\/li>\n<li>Breast tenderness<\/li>\n<li>Heavy menses, midcycle spotting (women)<\/li>\n<\/ul>\n<p><strong>Minder vaak maar belangrijk:<\/strong><\/p>\n<ul>\n<li><strong>Visuele stoornissen<\/strong> (blurred vision, scotomata, flashes of light, after-images, photosensitivity) &mdash; see dedicated section below<\/li>\n<li><strong>Ovarian hyperstimulation syndrome (OHSS)<\/strong> &mdash; less common with clomiphene than with injectable gonadotropins, but possible particularly in PCOS<\/li>\n<li><strong>Multiple pregnancy<\/strong> &mdash; 8-10% twin rate (mostly fraternal), much lower triplet rate (&lt;1%)<\/li>\n<li><strong>Ovarian cysts<\/strong> &mdash; usually functional and self-resolving; baseline ultrasound at the start of each cycle is recommended<\/li>\n<li><strong>Thin endometrium<\/strong> &mdash; cumulative oestrogen-antagonist effect at the uterine receptor; addressed by switching to letrozole if pregnancy is not achieved on clomiphene<\/li>\n<li><strong>Hostile cervical mucus<\/strong> &mdash; same mechanism; can reduce sperm penetration<\/li>\n<li><strong>Liver function abnormalities<\/strong> &mdash; rare; baseline LFTs and periodic monitoring on long courses (men)<\/li>\n<\/ul>\n<h2 id=\"visual\" class=\"wp-block-heading\">Visual disturbances &mdash; STOP and seek review<\/h2>\n<p>Visual side effects affect approximately 1-2% of patients and are dose-related. Symptoms include blurred vision, scotomata (blind spots), flashes of light, double vision, after-images, photosensitivity, and rarely persistent visual field defects.<\/p>\n<p><strong>If you develop any visual disturbance while taking clomiphene:<\/strong><\/p>\n<ul>\n<li><strong>Stop the medication immediately<\/strong><\/li>\n<li>Contact your prescriber promptly<\/li>\n<li>Most visual symptoms resolve within days-to-weeks of stopping; rare cases of persistent or irreversible visual changes have been reported<\/li>\n<li>Clomiphene should not be re-started after visual disturbances; switch to letrozole if ovulation induction is needed<\/li>\n<li>Avoid driving or operating machinery while symptoms persist<\/li>\n<\/ul>\n<h2 id=\"contraindications\" class=\"wp-block-heading\">Contra-indicaties &amp; waarschuwingen<\/h2>\n<p><strong>Do not take Clomiford if you have:<\/strong><\/p>\n<ul>\n<li>Pregnancy &mdash; clomiphene is teratogenic in animal studies; pregnancy must be excluded before each cycle<\/li>\n<li>Liver disease (active or previous)<\/li>\n<li>Undiagnosed abnormal uterine bleeding<\/li>\n<li>Ovarian cysts (other than known PCOS-related cysts) or enlarged ovaries<\/li>\n<li>Hormone-dependent cancer (breast, endometrial, ovarian)<\/li>\n<li>Pituitary tumour<\/li>\n<li>Uncontrolled thyroid or adrenal dysfunction (treat the underlying disorder first)<\/li>\n<li>Visual disturbances (current or with previous clomiphene cycles)<\/li>\n<li>Hypersensitivity to clomiphene citrate<\/li>\n<\/ul>\n<p><strong>Wees voorzichtig bij:<\/strong><\/p>\n<ul>\n<li>PCOS (higher risk of multi-follicular response and OHSS &mdash; close monitoring recommended)<\/li>\n<li>Thrombophilia or prior VTE (clomiphene increases oestradiol which is a thrombosis risk factor)<\/li>\n<li>Endometriosis (clomiphene may exacerbate)<\/li>\n<li>Migraine, epilepsy, depression<\/li>\n<\/ul>\n<h2 id=\"interactions\" class=\"wp-block-heading\">Geneesmiddelinteracties<\/h2>\n<ul>\n<li><strong>Other ovulation-induction agents<\/strong> (letrozole, FSH, hMG) &mdash; do not combine without specialist supervision; OHSS and multi-pregnancy risk multiply<\/li>\n<li><strong>hCG (Eutrig HP, HUCOG, Pregnyl)<\/strong> &mdash; commonly co-administered as an ovulation trigger after clomiphene-induced follicular growth, and routinely combined in male PCT\/HPG-axis-restoration protocols. Intentional combination, not a harmful interaction.<\/li>\n<li><strong>Tamoxifen<\/strong> &mdash; similar SERM mechanism; combined use only in specialist PCT or fertility protocols<\/li>\n<li><strong>Aromataseremmers<\/strong> (anastrozole) &mdash; sometimes co-prescribed in male protocols to manage clomiphene-driven oestradiol<\/li>\n<li><strong>Bexarotene<\/strong> &mdash; reduces clomiphene effect<\/li>\n<li><strong>Anabolic-androgenic steroids and exogenous testosterone<\/strong> &mdash; suppress endogenous LH\/FSH and would defeat clomiphene&#8217;s mechanism. PCT protocols administer clomiphene AFTER stopping AAS, not concurrently.<\/li>\n<\/ul>\n<h2 id=\"comparisons\" class=\"wp-block-heading\">How Clomiford compares to alternatives<\/h2>\n<p><strong>Clomiford vs Clomisign &mdash; both are clomiphene<\/strong> with identical pharmacology. The difference is formulation flexibility:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/clomisign\/\"><strong>Clomisign (Cipla)<\/strong><\/a> &mdash; single 50 mg strength, 30-180 tablet packs, simpler stocking<\/li>\n<li><strong>Clomiford (Sun Pharma)<\/strong> &mdash; 25 \/ 50 \/ 100 mg strengths, 30-800 tablet packs, more flexible for micro-dosing and large-cycle PCT regimens<\/li>\n<\/ul>\n<p><strong>For women (ovulation induction):<\/strong><\/p>\n<ul>\n<li><strong>Letrozole 2.5-5 mg\/day<\/strong> &mdash; aromatase inhibitor, increasingly first-line for PCOS (PPCOS-II trial showed higher live-birth rate vs clomiphene in PCOS), no thin-endometrium effect, lower multiple-pregnancy rate. Off-label in many jurisdictions but well-supported. Often the next step if 3 clomiphene cycles fail.<\/li>\n<li><strong>Gonadotropins (FSH, hMG)<\/strong> &mdash; injectable, more potent, more controllable but much higher OHSS and multi-pregnancy risk; reserved for clomiphene\/letrozole failures or IVF<\/li>\n<li><strong>Metformine<\/strong> &mdash; insulin-sensitiser, useful adjunct in insulin-resistant PCOS; modest standalone effect<\/li>\n<\/ul>\n<p><strong>For men (hypogonadism &amp; PCT):<\/strong><\/p>\n<ul>\n<li><strong>Direct testosterone replacement (TRT)<\/strong> &mdash; gels, patches, injections. Faster symptom relief but suppresses endogenous LH\/FSH and shuts down spermatogenesis &mdash; NOT for men wanting fertility.<\/li>\n<li><strong>Enclomiphene citrate<\/strong> &mdash; the pure anti-oestrogenic isomer of clomiphene; theoretically fewer side effects than racemic clomiphene; available in some markets<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/eutrig-hp-5000iu-injection\/\"><strong>Eutrig HP (hCG 5,000 IU)<\/strong><\/a> en <a href=\"https:\/\/medsbase.com\/nl\/hucog-5000iu-injection\/\"><strong>HUCOG 5000<\/strong><\/a> &mdash; LH analogues, directly stimulate Leydig cells. Commonly combined with clomiphene in PCT and HPG-axis-restoration protocols.<\/li>\n<li><strong>Anastrozole \/ letrozole<\/strong> &mdash; aromatase inhibitors; reduce oestradiol so the hypothalamus increases GnRH; sometimes used as alternative or adjunct to clomiphene<\/li>\n<\/ul>\n<h2 id=\"storage\" class=\"wp-block-heading\">Opslag &amp; houdbaarheid<\/h2>\n<p>Store Clomiford tablets below 25&deg;C in the original blister pack. Protect from moisture and light. Keep out of reach of children. Do not use after the expiry date printed on the carton.<\/p>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3 class=\"wp-block-heading\">What&#8217;s the difference between Clomiford and Clomisign?<\/h3>\n<p>Both contain identical clomiphene citrate at equivalent doses, so the pharmacology is the same. Clomiford is manufactured by Sun Pharma and comes in three strengths (25, 50 and 100 mg) with pack sizes up to 800 tablets &mdash; useful for micro-dosing or large-cycle PCT protocols. Clomisign is Cipla&#8217;s 50 mg single-strength version with smaller packs (up to 180 tablets), suited for shorter female fertility cycles. Choose based on the strength flexibility you need.<\/p>\n<h3 class=\"wp-block-heading\">Welke sterkte moet ik bestellen?<\/h3>\n<p>Depends on your prescription. <strong>50 mg<\/strong> is the standard for female ovulation induction and male PCT starter doses. <strong>100 mg<\/strong> is for second-cycle female escalation or aggressive PCT regimens. <strong>25 mg<\/strong> is for male hypogonadism micro-dosing (12.5-25 mg every other day or daily, particularly for younger men trying to maintain testosterone without side effects), or for women very sensitive to clomiphene side effects who tolerate a lower starting dose better. If you&#8217;re unsure, follow your prescriber&#8217;s recommendation.<\/p>\n<h3 class=\"wp-block-heading\">When will I ovulate after taking Clomiford?<\/h3>\n<p>Ovulation typically occurs 5-12 days after the last clomiphene tablet, with most women ovulating around cycle day 14-16. Confirm with ultrasound follicle tracking, a mid-luteal progesterone level, or LH-surge home kits.<\/p>\n<h3 class=\"wp-block-heading\">What is the chance of twins on clomiphene?<\/h3>\n<p>Approximately 8-10% of pregnancies conceived on clomiphene are twins (almost all fraternal, from two follicles releasing eggs in the same cycle). Triplet pregnancies are rare (&lt;1%). This is higher than the spontaneous twin rate of ~1-2% but lower than with injectable gonadotropins.<\/p>\n<h3 class=\"wp-block-heading\">Why is clomiphene limited to 6 cycles?<\/h3>\n<p>The cumulative pregnancy benefit plateaus after about 6 ovulatory cycles &mdash; if pregnancy hasn&#8217;t occurred by then, additional cycles add little benefit and the recommendation is to switch to letrozole, gonadotropins, IUI, or IVF. Older concerns about clomiphene increasing ovarian cancer risk with very prolonged use have not been confirmed in modern studies, but the 6-cycle ceiling remains the standard guidance.<\/p>\n<h3 class=\"wp-block-heading\">Can men take Clomiford for low testosterone?<\/h3>\n<p>Yes &mdash; off-label use of clomiphene for male secondary hypogonadism is well-established, particularly for younger men who wish to maintain fertility. Common starting protocol: 25 mg every other day or daily, titrated to target testosterone. Unlike testosterone replacement, clomiphene preserves the natural HPG axis and spermatogenesis. Should be supervised by an endocrinologist or men&#8217;s-health physician with baseline and 6-12 week bloodwork (testosterone, oestradiol, LH, FSH, SHBG, prolactin, full blood count, LFTs).<\/p>\n<h3 class=\"wp-block-heading\">What is a typical post-cycle therapy (PCT) protocol with Clomiford?<\/h3>\n<p>Common PCT protocols use clomiphene with stepped tapering: <strong>100 mg\/day for the first 2 weeks<\/strong>, <strong>50 mg\/day for weeks 3-4<\/strong>, <strong>25 mg\/day for weeks 5-6<\/strong>. Often combined with hCG (1,500-3,000 IU 2-3&times;\/week) for the first 2-4 weeks to re-prime the testes, and sometimes with tamoxifen 20 mg\/day. The 25 \/ 50 \/ 100 mg strength range of Clomiford allows the entire stepped protocol from a single product. Strongly recommend endocrinologist or experienced men&#8217;s-health prescriber supervision and serial bloodwork (LH, FSH, total testosterone, oestradiol).<\/p>\n<h3 class=\"wp-block-heading\">What if I get visual disturbances?<\/h3>\n<p><strong>Stop Clomiford immediately and contact your prescriber.<\/strong> Visual disturbances affect 1-2% of patients and are usually reversible if the medication is stopped &mdash; but rare cases of persistent visual changes have been reported. Clomiphene should not be re-started after visual symptoms; letrozole is the standard alternative.<\/p>\n<h3 class=\"wp-block-heading\">Should I take Clomiford with food?<\/h3>\n<p>You can take clomiphene with or without food. Take it at approximately the same time each day. Mild nausea is more common on an empty stomach &mdash; if so, take it with a small meal.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol while taking Clomiford?<\/h3>\n<p>Moderate alcohol does not interact with clomiphene directly. However, regular heavy drinking is itself a fertility-impairing factor (in both women and men), so minimising alcohol throughout a fertility cycle is sensible.<\/p>\n<h3 class=\"wp-block-heading\">Where can I order Clomiford online?<\/h3>\n<p>You can order Clomiford tablets from MedsBase in three strengths (25 mg, 50 mg, 100 mg) and pack sizes from 30 to 800 tablets. Orders ship worldwide with discreet packaging. Clomiford is specialist-supervised worldwide &mdash; please ensure you have a valid clinical indication and supervising clinician before ordering.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:24px 0;border-radius:4px;\">\n<strong>\u2695 Medisch disclaimer.<\/strong> This page is for informational purposes only and does not replace medical advice from a qualified healthcare professional. Fertility medications and hormone-modulating drugs are <strong>specialist-supervised worldwide<\/strong> and must be used only under direct medical supervision &mdash; including baseline endocrine testing, ultrasound monitoring where applicable, and a defined treatment plan. MedsBase does not provide diagnosis, prescription, or clinical recommendations.\n<\/div>\n<p class=\"medsbase-bundle-link-2026-05-01\" data-marker=\"mb-bundle-link-pct-stack\">Clomiphene-only PCT works for hormone restart but lacks the breast-tissue protection a SERM like tamoxifen provides; the standard protocol pairs both \u2014 see our <a href='\/nl\/pct-stack\/'>PCT Stack (Clomisign 50 mg + Tamoxilon 20 mg)<\/a> for the bundled dual-SERM regimen at matched supply tiers.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Gerelateerde alternatieven<\/h3>\n<p>Andere producten in <strong>Mannelijke gezondheid<\/strong> die klanten ook bekijken:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/himcolin-gel\/\">Himcolin Gel<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/tamsuheal\/\">Tamsuheal<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/deetor\/\">Deetor<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/super-p-force\/\">Super P Force<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/vitara-v\/\">Vitara-V<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<h5>\u2705 Boosts Women&#8217;s Ovulation<br \/>\n\u2705 Aids Pregnancy Odds<br \/>\n\u2705 Men&#8217;s T-Level Restore<br \/>\n\u2705 Blocks Low T-Effects<\/h5>\n<p><span style=\"color: #999999\"><span style=\"color: #000000\"><span style=\"color: #808080\"><strong>Clomiford<\/strong> bevat <strong>Clomiphene.<\/strong><\/span><\/span><br \/>\n<\/span><\/p>","protected":false},"featured_media":54863,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3521,3596,3522,3142],"product_tag":[3829,3830,3831],"class_list":{"0":"post-54862","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-fertility","7":"product_cat-fertility-supplements-for-men","8":"product_cat-fertility-supplements-for-women","9":"product_cat-mens-health","10":"product_tag-clomid","11":"product_tag-clomiford","12":"product_tag-clomiphene","14":"first","15":"instock","16":"shipping-taxable","17":"purchasable","18":"product-type-variable","19":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/54862","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=54862"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/54863"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=54862"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=54862"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=54862"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=54862"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}