{"id":55802,"date":"2024-02-07T05:41:12","date_gmt":"2024-02-07T05:41:12","guid":{"rendered":"https:\/\/medsname.com\/bacloheal\/"},"modified":"2026-05-01T10:49:13","modified_gmt":"2026-05-01T10:49:13","slug":"bacloheal","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/bacloheal\/","title":{"rendered":"Bacloheal"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Bacloheal?<\/h3>\n<p style=\"margin:0;\"><strong>Bacloheal<\/strong> is een oraal <strong>baclofen<\/strong> (10 mg) tablet \u2014 a <strong>GABA<sub>B<\/sub> receptor agonist<\/strong> gebruikt voor de behandeling van <strong>spasticity<\/strong> associated with <strong>multiple sclerosis (MS)<\/strong>, <strong>spinal cord injury<\/strong>, <strong>cerebral palsy<\/strong>, and other upper motor neuron conditions. It reduces muscle tone and spasm frequency by inhibiting excitatory neurotransmission at the spinal level. Starting dose: <strong>5 mg three times daily<\/strong>, titrated every 3 days up to a usual maintenance of <strong>40&ndash;80 mg\/day<\/strong> (maximum 80 mg\/day in divided doses). Common side effects: drowsiness, dizziness, weakness, nausea. <strong>Nooit abrupt stoppen<\/strong> \u2014 abrupt withdrawal can cause hallucinations, seizures, and life-threatening autonomic instability.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Wat u krijgt bij MedsBase:<\/strong> WHO-GMP gecertificeerde fabrikant \u00b7 Discrete verpakking \u00b7 Wereldwijde verzending \u00b7 1.400+ geverifieerde <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">klantbeoordelingen<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n<h2 class=\"wp-block-heading\">What Is Bacloheal?<\/h2>\n<p>Bacloheal is an oral tablet containing <strong>baclofen 10 mg<\/strong>, manufactured by Healing Pharma. Baclofen has been in clinical use since the 1970s and remains on the <strong>WHO Model-lijst van essenti\u00eble geneesmiddelen<\/strong> as a first-line antispasticity agent. Bacloheal is bioequivalent to the originator brand <strong>Lioresal<\/strong> (Novartis).<\/p>\n<p>Unlike benzodiazepines, which act broadly on GABA<sub>A<\/sub> receptors throughout the brain, baclofen is selective for <strong>GABA<sub>B<\/sub> receptors in the spinal cord<\/strong> \u2014 meaning it reduces spasticity at its source with less cognitive impairment, less abuse potential and no controlled-substance restrictions.<\/p>\n<h2 class=\"wp-block-heading\">How Does Bacloheal (Baclofen) Work?<\/h2>\n<p>Baclofen is a structural analogue of the inhibitory neurotransmitter <strong>GABA (gamma-aminobutyric acid)<\/strong>. It selectively activates <strong>GABA<sub>B<\/sub> receptoren<\/strong> on presynaptic terminals in the spinal cord, which reduces the release of excitatory neurotransmitters (glutamate, aspartate). This decreases both mono- and polysynaptic reflex transmission, lowering muscle tone without eliminating voluntary movement.<\/p>\n<p>Unlike benzodiazepines (which act on GABA<sub>A<\/sub>), baclofen does not produce significant anxiolytic or anticonvulsant effects at therapeutic spasticity doses \u2014 its action is predominantly spinal rather than supraspinal.<\/p>\n<h2 class=\"wp-block-heading\">Indicaties<\/h2>\n<ul>\n<li><strong>Multiple sclerosis<\/strong> \u2014 reduces flexor and extensor spasms, clonus, and painful muscle stiffness<\/li>\n<li><strong>Spinal cord injury\/disease<\/strong> \u2014 traumatic, inflammatory, degenerative, or neoplastic<\/li>\n<li><strong>Cerebral palsy<\/strong> (particularly in adolescents and adults)<\/li>\n<li><strong>Stroke-related spasticity<\/strong> (off-label, adjunct)<\/li>\n<li><strong>Trigeminal neuralgia<\/strong> (off-label \u2014 second-line after carbamazepine)<\/li>\n<li><strong>Alcohol withdrawal\/craving<\/strong> (off-label \u2014 growing evidence, approved in France)<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Dosing and Administration<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:0 0 24px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px 14px;text-align:left;\">Fase<\/th>\n<th style=\"padding:10px 14px;text-align:left;\">Dosering<\/th>\n<th style=\"padding:10px 14px;text-align:left;\">Schema<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px 14px;\">Days 1&ndash;3<\/td>\n<td style=\"padding:10px 14px;\">5 mg<\/td>\n<td style=\"padding:10px 14px;\">Three times daily<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px 14px;\">Days 4&ndash;6<\/td>\n<td style=\"padding:10px 14px;\">10 mg<\/td>\n<td style=\"padding:10px 14px;\">Three times daily<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px 14px;\">Days 7&ndash;9<\/td>\n<td style=\"padding:10px 14px;\">15 mg<\/td>\n<td style=\"padding:10px 14px;\">Three times daily<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px 14px;\">Days 10+<\/td>\n<td style=\"padding:10px 14px;\">20 mg<\/td>\n<td style=\"padding:10px 14px;\">Three times daily<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px 14px;\">Maximum<\/td>\n<td style=\"padding:10px 14px;\">80 mg\/day<\/td>\n<td style=\"padding:10px 14px;\">Divided into 3&ndash;4 doses<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Take with food to reduce GI side effects. Use the lowest effective dose. In renal impairment, reduce dose \u2014 baclofen is ~70&ndash;85% renally excreted.<\/p>\n<h2 class=\"wp-block-heading\">Bijwerkingen<\/h2>\n<p><strong>Common (\u226510%):<\/strong> drowsiness, dizziness, weakness\/fatigue, nausea, headache, constipation.<\/p>\n<p><strong>Minder vaak:<\/strong> confusion, urinary frequency\/retention, insomnia, hypotension, dry mouth.<\/p>\n<p><strong>Ernstig:<\/strong> respiratory depression (overdose or renal impairment), seizures (on abrupt withdrawal), hallucinations, autonomic dysreflexia (in spinal cord injury patients).<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:16px 0;border-radius:4px;\"><strong>&#9888; Withdrawal warning:<\/strong> Never stop baclofen abruptly after prolonged use. Abrupt discontinuation can cause hallucinations, seizures, high fever, altered mental status, rebound spasticity, and rhabdomyolysis. Taper gradually over <strong>1&ndash;2 weeks minimum<\/strong> (reduce by 5&ndash;10 mg every 3&ndash;5 days).<\/div>\n<h2 class=\"wp-block-heading\">Waarschuwingen en voorzorgsmaatregelen<\/h2>\n<ul>\n<li><strong>Abrupt withdrawal is dangerous.<\/strong> Sudden cessation after prolonged use (even 2&ndash;4 weeks) can trigger hallucinations, seizures, high fever, psychosis and rhabdomyolysis &mdash; a syndrome resembling neuroleptic malignant syndrome. Taper over 1&ndash;2 weeks minimum (reduce by 5&ndash;10 mg every 3&ndash;5 days).<\/li>\n<li><strong>Nierfunctiestoornis.<\/strong> Baclofen is 70&ndash;85% renally excreted. In CrCl &lt;30 mL\/min, accumulation causes oversedation, respiratory depression and coma. Dose-reduce and monitor closely. Some guidelines contra-indicate oral baclofen at eGFR &lt;15.<\/li>\n<li><strong>Older adults.<\/strong> Falls risk increases due to sedation and muscle weakness. Start at 5 mg once or twice daily and titrate very slowly.<\/li>\n<li><strong>Autonomic dysreflexia.<\/strong> In spinal cord injury patients above T6, baclofen dose changes can precipitate autonomic dysreflexia. Titrate under specialist supervision.<\/li>\n<li><strong>Epilepsy.<\/strong> Baclofen lowers the seizure threshold at high doses. Use caution in patients with a seizure history.<\/li>\n<li><strong>Zwangerschap &amp; borstvoeding.<\/strong> Limited data. Animal studies show skeletal abnormalities at high doses. Use only if clearly needed. Baclofen is excreted in breast milk &mdash; monitor the infant for sedation.<\/li>\n<li><strong>Driving and machinery.<\/strong> Baclofen causes drowsiness and slowed reactions, especially during titration. Do not drive until you know how it affects you.<\/li>\n<li><strong>CNS depressant interactions.<\/strong> Additive sedation with opioids, benzodiazepines, alcohol, antihistamines and antipsychotics. Risk of fatal respiratory depression with opioids.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Contraindications &mdash; Who Should NOT Take Bacloheal<\/h2>\n<ul>\n<li>Known hypersensitivity to baclofen or any excipient<\/li>\n<li>Active peptic ulcer disease (baclofen stimulates gastric acid secretion)<\/li>\n<li>Porfyrie<\/li>\n<li>Severe renal impairment without dose adjustment and monitoring<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Geneesmiddelinteracties<\/h2>\n<ul>\n<li><strong>CNS depressants<\/strong> (opioids, benzodiazepines, alcohol): Additive sedation and respiratory depression<\/li>\n<li><strong>Antihypertensives:<\/strong> Additive hypotension \u2014 monitor blood pressure<\/li>\n<li><strong>Tricyclic antidepressants:<\/strong> May potentiate baclofen-induced muscle hypotonia<\/li>\n<li><strong>Levodopa\/carbidopa:<\/strong> Confusion, hallucinations reported with concurrent use in Parkinson patients<\/li>\n<li><strong>NSAIDs (ibuprofen, naproxen):<\/strong> May reduce renal clearance of baclofen \u2014 monitor for toxicity<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Bewaaradvies<\/h2>\n<ul>\n<li>Bewaren bij kamertemperatuur, <strong>15\u201330\u00b0C<\/strong>. Protect from moisture and light.<\/li>\n<li>Keep in original blister packaging until use.<\/li>\n<li>Do not store in the bathroom &mdash; humidity degrades the tablet.<\/li>\n<li>Keep out of reach of children &mdash; baclofen overdose causes profound sedation and respiratory depression.<\/li>\n<li>Do not use after the expiry date printed on the blister.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Related Categories on MedsBase<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/neurological-conditions-and-epilepsy\/\">Bekijk alle neurologische &amp; epilepsiemedicijnen<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/pain-relief-medication\/\">Browse pain relief medications<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/mental-health-and-psychiatric-medications\/\">Bekijk medicijnen voor geestelijke gezondheid &amp; psychiatrie<\/a><\/li>\n<\/ul>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3 class=\"wp-block-heading\">What is Bacloheal used for?<\/h3>\n<p>Bacloheal contains <strong>baclofen 10 mg<\/strong>, a muscle relaxant used to reduce <strong>spasticity<\/strong> (muscle stiffness and spasms) in conditions such as multiple sclerosis, spinal cord injury, cerebral palsy, and stroke.<\/p>\n<h3 class=\"wp-block-heading\">How quickly does baclofen work for spasticity?<\/h3>\n<p>Some relief may be noticed within <strong>3\u20135 dagen<\/strong> of reaching a therapeutic dose. Full benefit usually takes <strong>1&ndash;4 weeks<\/strong> of gradual titration. The goal is not to eliminate all tone (some tone is needed for posture and transfers) but to reduce painful spasms and improve function.<\/p>\n<h3 class=\"wp-block-heading\">What happens if I stop baclofen suddenly?<\/h3>\n<p>Abrupt withdrawal after prolonged use can cause <strong>hallucinations, seizures, high fever, confusion, and rebound spasticity<\/strong> \u2014 a potentially life-threatening syndrome resembling neuroleptic malignant syndrome. Always taper gradually over 1&ndash;2 weeks.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol while taking Bacloheal?<\/h3>\n<p><strong>Vermijd alcohol.<\/strong> Both baclofen and alcohol are CNS depressants \u2014 combining them amplifies drowsiness, dizziness, impaired coordination, and respiratory depression risk.<\/p>\n<h3 class=\"wp-block-heading\">Is baclofen the same as a benzodiazepine?<\/h3>\n<p>No. Baclofen acts on <strong>GABA<sub>B<\/sub> receptoren<\/strong> (predominantly spinal), while benzodiazepines act on <strong>GABA<sub>A<\/sub> receptoren<\/strong> (predominantly supraspinal). Baclofen is not a controlled substance, has minimal abuse potential compared to benzodiazepines, and does not produce the same anxiolytic or euphoric effects.<\/p>\n<h3 class=\"wp-block-heading\">Is Bacloheal the same as Lioresal?<\/h3>\n<p>Both contain baclofen. Lioresal is the original brand. Bacloheal is a bioequivalent generic at a lower cost.<\/p>\n<h3 class=\"wp-block-heading\">Can baclofen be used for back pain?<\/h3>\n<p>Baclofen is sometimes prescribed off-label for <strong>acute low back pain with muscle spasm<\/strong>, though evidence is limited compared to its well-established role in neurological spasticity. It is not a first-line analgesic for mechanical back pain.<\/p>\n<h3 class=\"wp-block-heading\">Does baclofen cause weight gain?<\/h3>\n<p>Weight gain is not a common side effect at therapeutic spasticity doses. However, reduced physical activity from sedation can contribute to weight change over time.<\/p>\n<h3 class=\"wp-block-heading\">What is the difference between oral and intrathecal baclofen?<\/h3>\n<p>Intrathecal baclofen is delivered directly into the spinal fluid via an implanted pump \u2014 used when oral baclofen is ineffective or causes intolerable sedation. Intrathecal doses are <strong>100&ndash;1,000 times smaller<\/strong> than oral doses, with fewer systemic side effects.<\/p>\n<h3 class=\"wp-block-heading\">Can I drive while taking Bacloheal?<\/h3>\n<p>Baclofen causes drowsiness and slowed reactions, especially during titration. <strong>Do not drive or operate heavy machinery<\/strong> until you know how the drug affects you. Sedation often improves after the first 1&ndash;2 weeks at a stable dose.<\/p>\n<h3 class=\"wp-block-heading\">Is baclofen safe in kidney disease?<\/h3>\n<p>Baclofen is predominantly renally excreted. In <strong>moderate-to-severe renal impairment<\/strong>, accumulation can cause toxicity (oversedation, respiratory depression, coma). Dose reduction and close monitoring are essential. Some guidelines recommend avoiding oral baclofen at eGFR &lt;15 mL\/min.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:24px 0;border-radius:4px;font-size:13px;\"><strong>Medische disclaimer:<\/strong> This page is for informational purposes only and does not replace professional medical advice. Always consult a qualified healthcare provider before starting, changing or stopping any medication. Dosing information reflects manufacturer labelling and published clinical guidance \u2014 individual requirements may differ.<\/div>\n<p class=\"medsbase-link-boost-2026-04-30\" data-marker=\"mb-link-boost-synaptol\">Patients on baclofen with troublesome drowsiness or those unable to tolerate the GABA-B side-effect profile may benefit from <a href='\/nl\/synaptol\/'>Synaptol (tolperisone 150 mg)<\/a> \u2014 a non-sedating sodium-channel-modulating muscle relaxant with a much milder CNS profile.<\/p>\n<p data-mb-link-target=\"gabasign\" style=\"margin-top:1em;font-size:0.95em;color:#444;border-left:3px solid #2c7cb0;padding:0.5em 0.75em;background:#f4f8fb;\"><strong>Zie ook:<\/strong> <a href=\"https:\/\/medsbase.com\/nl\/gabasign\/\"><strong>Gabasign 300 \/ 600 mg<\/strong><\/a> \u2014 Cipla&#8217;s gabapentin generic \u2014 same FDA-approved molecule, full dose range from 300 mg starter to 600 mg maintenance.<\/p>\n<p data-mb-link-target=\"synaptol\" style=\"margin-top:1em;font-size:0.95em;color:#444;border-left:3px solid #2c7cb0;padding:0.5em 0.75em;background:#f4f8fb;\"><strong>Zie ook:<\/strong> <a href=\"https:\/\/medsbase.com\/nl\/synaptol\/\"><strong>Synaptol 150 mg<\/strong><\/a> \u2014 tolperisone alternative when cyclobenzaprine sedation is unacceptable \u2014 centrally acting without H1 antihistamine drowsiness.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Gerelateerde alternatieven<\/h3>\n<p>Andere producten in <strong>Chronische aandoeningen<\/strong> die klanten ook bekijken:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/gabapin\/\">Gabapin<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/cytotam\/\">Cytotam<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/zolitas-ods\/\">Zolitas ODS<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/tiova-rotacaps\/\">Tiova Rotacaps<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/flucort-n-cream\/\">Flucort-N Cream<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Relieves muscle spasms<br \/>\n\u2705 Alleviates muscle stiffness<br \/>\n\u2705 Enhances muscle flexibility<br \/>\n\u2705 Improves muscle movement<br \/>\n\u2705 Aids in muscle relaxation<\/p>\n<p>Bacloheal contains Baclofen.<\/p>","protected":false},"featured_media":55803,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3468],"product_tag":[3987,3989],"class_list":{"0":"post-55802","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-neurological-conditions-and-epilepsy","9":"product_tag-baclofen","10":"product_tag-bacloheal","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/55802","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=55802"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/55803"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=55802"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=55802"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=55802"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=55802"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}