{"id":57565,"date":"2024-02-27T17:50:31","date_gmt":"2024-02-27T17:50:31","guid":{"rendered":"https:\/\/medsname.com\/rtqs-200\/"},"modified":"2026-04-30T10:24:25","modified_gmt":"2026-04-30T10:24:25","slug":"rtqs-200","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/rtqs-200\/","title":{"rendered":"Rtqs 200"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8d6;border-left:4px solid #f5c518;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<h3 style=\"margin-top:0;\">Snelle antwoord<\/h3>\n<p><strong>Rtqs 200<\/strong> bevat <strong>hydroxychloroquine sulfate<\/strong> 200 mg (RPG Life Sciences). It treats and prevents <strong>chloroquine-sensitive malaria<\/strong>, and is the first-line aminoquinoline for <strong>rheumatoid arthritis<\/strong>, <strong>systemic lupus erythematosus<\/strong>, <strong>discoid lupus<\/strong>, en <strong>Sj\u00f6gren&#8217;s syndrome<\/strong>. Dose: 400 mg\/day for autoimmune disease (long-term maintenance \u2264 5 mg\/kg\/day actual body weight); 800 mg loading then 400 mg at 6 \/ 24 \/ 48 h for acute uncomplicated chloroquine-sensitive malaria. <strong>Mandatory baseline + annual ophthalmology screening<\/strong> after 5 years of continuous use to detect retinopathy. Modern endemic areas (sub-Saharan Africa, India, Southeast Asia, Amazon) have widespread chloroquine resistance \u2014 hydroxychloroquine is NOT the right prophylaxis for those destinations. Take with food to reduce GI upset.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f4f4;border:1px solid #e0e0e0;border-radius:6px;padding:14px 18px;margin:18px 0;font-size:14px;line-height:1.5;\"><strong>\ud83c\udfed WHO-GMP gecertificeerde fabrikant<\/strong> &nbsp;\u00b7&nbsp; <strong>\ud83d\udce6 Discrete verpakking<\/strong> &nbsp;\u00b7&nbsp; <strong>\ud83c\udf0d Wereldwijde verzending<\/strong> &nbsp;\u00b7&nbsp; <strong>\u2b50 <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">1.400+ klantbeoordelingen<\/a><\/strong><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:13px;color:#555;margin:10px 0 18px;\">\ud83d\udee1\ufe0f Every order is covered by our <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 if your parcel does not arrive within 20 business days we ship a free replacement on EMS or ITPS courier.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Rtqs 200 is sourced from a WHO-GMP certified manufacturer and shipped worldwide in discreet packaging. Every order is backed by our <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance Policy<\/a> and supported by our <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">1.400+ klantbeoordelingen<\/a>. Worldwide shipping with no prescription paperwork.<\/p>\n<h2>About Rtqs 200<\/h2>\n<p>Rtqs 200 is a 200 mg hydroxychloroquine sulfate tablet manufactured by RPG Life Sciences under WHO-GMP certified conditions. Hydroxychloroquine is a 4-aminoquinoline antimalarial that doubles as the workhorse <strong>conventional synthetic disease-modifying anti-rheumatic drug (csDMARD)<\/strong> for mild-to-moderate rheumatoid arthritis and connective-tissue disease, with the lowest toxicity profile of any DMARD when dosed correctly.<\/p>\n<h2>How hydroxychloroquine works<\/h2>\n<p>Hydroxychloroquine accumulates in the acidic lysosomes of cells. In <strong>malaria parasites<\/strong> it interferes with haemoglobin digestion in the food vacuole, allowing toxic free haem to accumulate and kill the parasite. In <strong>autoimmune disease<\/strong> the lysosomotropic effect raises lysosomal pH, which interferes with antigen processing by dendritic cells, dampens Toll-like receptor signalling (especially TLR-7 and TLR-9 which recognise self-nucleic acids), and reduces interferon-\u03b1 production. The dual mechanism explains why a single drug treats two unrelated diseases.<\/p>\n<p>Half-life is ~ 40 days (steady state 4\u20136 weeks). Effect on autoimmune disease takes 8\u201312 weeks to develop and continues to deepen over 6 months \u2014 patience and adherence matter.<\/p>\n<h2>Indicaties en dosering<\/h2>\n<div style=\"overflow-x:auto;margin:18px 0;\">\n<table style=\"width:100%;border-collapse:collapse;font-size:14px;\">\n<thead>\n<tr>\n<th style=\"background:#2c7cb0;color:#fff;padding:8px;text-align:left;\">Indicatie<\/th>\n<th style=\"background:#2c7cb0;color:#fff;padding:8px;text-align:left;\">Dosering<\/th>\n<th style=\"background:#2c7cb0;color:#fff;padding:8px;text-align:left;\">Duur \/ opmerkingen<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Rheumatoid arthritis (mild\u2013moderate)<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">200\u2013400 mg\/day in 1\u20132 divided doses (max 5 mg\/kg\/day actual body weight)<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Onset 8\u201312 weeks. Long-term maintenance. Often combined with methotrexate or sulfasalazine.<\/td>\n<\/tr>\n<tr style=\"\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Systemische lupus erythematosus (SLE)<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">200\u2013400 mg\/day, max 5 mg\/kg\/day<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Background therapy for almost all SLE patients per EULAR \u2014 reduces flares, organ damage, thrombosis, and improves survival.<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Discoid \/ cutaneous lupus<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">200\u2013400 mg\/dag<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">First-line systemic for skin-only lupus. Can take 8\u201312 weeks for visible improvement.<\/td>\n<\/tr>\n<tr style=\"\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Sj\u00f6gren&#8217;s syndrome<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">200\u2013400 mg\/dag<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Modest-evidence improvement in fatigue + arthralgia; little effect on dryness.<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Acute uncomplicated chloroquine-sensitive P. falciparum \/ P. vivax \/ P. ovale \/ P. malariae<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">800 mg loading \u2192 400 mg at 6 h \u2192 400 mg at 24 h \u2192 400 mg at 48 h (total 2 g over 48 h)<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Treatment course only \u2014 for chloroquine-sensitive areas. Add primaquine for radical cure of vivax\/ovale.<\/td>\n<\/tr>\n<tr style=\"\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Chloroquine-sensitive malaria prophylaxis<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">400 mg once weekly<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Start 1\u20132 weeks before travel, continue weekly during exposure, continue 4 weeks after return. Limited modern utility \u2014 most destinations are resistant.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;font-size:14px;line-height:1.6;\"><strong>Retinal-toxicity red-box.<\/strong> Hydroxychloroquine accumulates in retinal pigment epithelium. <strong>Risk of irreversible bull&#8217;s-eye maculopathy<\/strong> rises sharply after 5 years of continuous use, especially at doses &gt; 5 mg\/kg\/day actual body weight, with renal impairment, with concurrent tamoxifen, or in patients with pre-existing retinal disease. <strong>American Academy of Ophthalmology \/ Royal College of Ophthalmologists guidance: baseline fundus exam at start of long-term therapy + annual screening from year 5 onwards<\/strong> using spectral-domain OCT, automated visual field 10-2 (white test object), and fundus autofluorescence. Earlier screening if dose &gt; 5 mg\/kg\/day, renal CrCl &lt; 60 mL\/min, or concurrent tamoxifen. Stop the drug at the first sign of pre-toxicity \u2014 damage already established does not reverse.<\/div>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;font-size:14px;line-height:1.6;\"><strong>G6PD note.<\/strong> Hydroxychloroquine has a much smaller G6PD-haemolysis signal than primaquine, but case reports exist in severe G6PD deficiency. If G6PD status is unknown, monitor for haemolysis (dark urine, pallor, fatigue) in the first weeks of high-dose therapy.<\/div>\n<h2>Controleschema<\/h2>\n<div style=\"overflow-x:auto;margin:18px 0;\">\n<table style=\"width:100%;border-collapse:collapse;font-size:14px;\">\n<thead>\n<tr>\n<th style=\"background:#2c7cb0;color:#fff;padding:8px;text-align:left;\">Time-point<\/th>\n<th style=\"background:#2c7cb0;color:#fff;padding:8px;text-align:left;\">Investigation<\/th>\n<th style=\"background:#2c7cb0;color:#fff;padding:8px;text-align:left;\">Reason<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Basislijn<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Eye exam (fundus + OCT + visual field), FBC, U&#038;E, LFTs, glucose, weight<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Establish retinal baseline + dose-by-actual-weight calculation + screen contraindications.<\/td>\n<\/tr>\n<tr style=\"\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Months 1\u20136<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Symptom review at each clinical contact<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">GI tolerance, headache, mood, skin rash, muscle weakness.<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Year 1, then annually<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">FBC + LFTs<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Rare cytopenias and rare hepatotoxicity.<\/td>\n<\/tr>\n<tr style=\"\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Year 5, then annually<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Comprehensive ophthalmology screening (OCT + 10-2 visual field + fundus autofluorescence)<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Detect early retinopathy before irreversible damage.<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Symptom-driven<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">CK + EMG if proximal weakness; nerve conduction if neuropathic symptoms<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Rare myopathy \/ neuromyopathy with long-term use.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<h2>Bijwerkingen<\/h2>\n<ul>\n<li><strong>Common (5\u201315 %):<\/strong> nausea, diarrhoea, abdominal cramping (mitigated by taking with food), headache, dizziness, mild itching, skin pigmentation (slate-grey patches in long-term users).<\/li>\n<li><strong>Less common (1\u20135 %):<\/strong> hair lightening, photosensitivity, mood change, vivid dreams, blurred vision (early reversible accommodation effect \u2014 distinct from late retinopathy), tinnitus.<\/li>\n<li><strong>Zeldzaam maar ernstig:<\/strong> retinopathy (long-term, dose-dependent \u2014 see red-box), cardiomyopathy \/ QT prolongation (especially with concurrent QT-prolongers), myopathy, neuromyopathy, agranulocytosis, severe cutaneous reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis, AGEP, drug rash with eosinophilia and systemic symptoms \/ DRESS).<\/li>\n<li><strong>Cardiaal:<\/strong> QTc prolongation is dose-dependent. Avoid combination with other QT-prolonging drugs (azithromycin, fluoroquinolones, ondansetron, methadone, antipsychotics) and correct electrolyte imbalance before high-dose therapy.<\/li>\n<\/ul>\n<h2>Geneesmiddelinteracties<\/h2>\n<div style=\"overflow-x:auto;margin:18px 0;\">\n<table style=\"width:100%;border-collapse:collapse;font-size:14px;\">\n<thead>\n<tr>\n<th style=\"background:#2c7cb0;color:#fff;padding:8px;text-align:left;\">Interactie<\/th>\n<th style=\"background:#2c7cb0;color:#fff;padding:8px;text-align:left;\">Effect<\/th>\n<th style=\"background:#2c7cb0;color:#fff;padding:8px;text-align:left;\">Beheer<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Digoxine<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Hydroxychloroquine raises digoxin level<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Monitor digoxin level; halve digoxin dose if needed.<\/td>\n<\/tr>\n<tr style=\"\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Insulin \/ sulfonylureas \/ metformin<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Hydroxychloroquine improves insulin sensitivity \u2192 hypoglycaemia risk<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Monitor blood glucose; reduce diabetic medication dose if symptomatic hypoglycaemia.<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Methotrexaat<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">No significant pharmacokinetic interaction; combined as standard csDMARD pair<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Combination is standard rheumatology practice.<\/td>\n<\/tr>\n<tr style=\"\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">QT-prolonging drugs (azithromycin, ondansetron, fluoroquinolones, methadone, antipsychotics)<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Additive QTc prolongation<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Avoid co-administration in patients with structural heart disease, electrolyte disturbance, or pre-existing long QT.<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Cyclosporine<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Hydroxychloroquine raises cyclosporine level<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Monitor cyclosporine level if combined.<\/td>\n<\/tr>\n<tr style=\"\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Antacids (Mg \/ Al hydroxide)<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Reduce hydroxychloroquine absorption ~ 30 %<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Separate by 4 hours.<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Mefloquine<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Both can lower seizure threshold<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Avoid combination; choose one antimalarial agent.<\/td>\n<\/tr>\n<tr style=\"\">\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Tamoxifen<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Synergistic retinal toxicity in long-term use<\/td>\n<td style=\"padding:8px;border-top:1px solid #e0e0e0;vertical-align:top;\">Use lowest effective dose; intensified ophthalmology screening.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<h2>Contra-indicaties en waarschuwingen<\/h2>\n<ul>\n<li><strong>Absolute:<\/strong> known hypersensitivity to 4-aminoquinolines; pre-existing retinopathy.<\/li>\n<li><strong>Voorzichtig:<\/strong> renal impairment (dose by actual body weight; consider dose reduction at CrCl &lt; 30 mL\/min), hepatic impairment, history of psoriasis (can flare), porphyria (can precipitate attack), G6PD deficiency, severe GI disease, neurological disease (rare seizures), psoriasis (flare risk).<\/li>\n<li><strong>Zwangerschap:<\/strong> compatible. Continuing hydroxychloroquine during pregnancy in lupus reduces flares and improves outcomes; ACR \/ EULAR \/ British Society for Rheumatology all recommend continuation. Crosses placenta \u2014 neonatal retina is not affected at maternal therapeutic dose.<\/li>\n<li><strong>Borstvoeding:<\/strong> compatible. Excreted in breast milk in tiny amounts.<\/li>\n<\/ul>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;font-size:14px;line-height:1.6;\"><strong>COVID-19 evidence note.<\/strong> Multiple high-quality randomised controlled trials (RECOVERY, SOLIDARITY, ORCHID, COVID-OUT, OVCH-19) have shown hydroxychloroquine does NOT reduce mortality, hospitalisation, or progression of COVID-19. The drug is not recommended for COVID-19 prophylaxis or treatment. Rtqs 200 is a malaria + autoimmune-disease medication only.<\/div>\n<h2>Opslag<\/h2>\n<p>Store below 25 \u00b0C in a dry place, in original packaging. Keep out of reach of children \u2014 paediatric overdose with a single 200 mg tablet has caused fatal cardiotoxicity in a small child.<\/p>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3>How long does Rtqs 200 take to work for rheumatoid arthritis or lupus?<\/h3>\n<p>Most patients notice meaningful improvement at 8\u201312 weeks; the benefit continues to deepen for 6 months. Do not stop early because of &#8220;no effect at 4 weeks&#8221;. Combination with methotrexate may be used for faster onset in higher-disease-activity rheumatoid arthritis.<\/p>\n<h3>Do I need an eye exam before starting?<\/h3>\n<p>Yes \u2014 baseline fundus + OCT + visual field. Annual screening from year 5 of continuous use, earlier if dose &gt; 5 mg\/kg\/day actual weight, renal CrCl &lt; 60, or concurrent tamoxifen.<\/p>\n<h3>Can I take Rtqs 200 for malaria prophylaxis on a Southeast Asia or Africa trip?<\/h3>\n<p>No. Most modern endemic regions have widespread chloroquine and hydroxychloroquine resistance. Use mefloquine, doxycycline, or atovaquone-proguanil. Speak to a travel-medicine clinic for destination-specific advice.<\/p>\n<h3>What dose should I take for autoimmune disease?<\/h3>\n<p>Long-term maintenance should not exceed 5 mg\/kg\/day of actual body weight (not ideal body weight). For most adults this works out at 200\u2013400 mg\/day. Higher doses raise the retinal-toxicity risk substantially.<\/p>\n<h3>Is het veilig tijdens de zwangerschap?<\/h3>\n<p>Yes. Continuing hydroxychloroquine during pregnancy in lupus reduces disease flares and adverse pregnancy outcomes. Stopping it in pregnancy is associated with increased lupus flare and worse maternal and foetal outcomes.<\/p>\n<h3>Mag ik alcohol drinken?<\/h3>\n<p>Moderate alcohol is acceptable. Avoid heavy drinking \u2014 both alcohol and hydroxychloroquine can rarely cause hepatotoxicity, and the combination raises the cardiac QT signal slightly.<\/p>\n<h3>Why does the doctor want a baseline weight?<\/h3>\n<p>The 5 mg\/kg\/day cap is calculated on actual body weight, not ideal body weight. Patients above ~80 kg often need 400 mg\/day; patients below ~50 kg often need 200 mg\/day to stay below the retinal-toxicity threshold.<\/p>\n<h3>Wat als ik een dosis vergeet?<\/h3>\n<p>Take it as soon as you remember unless it is close to the next dose. Do not double up. The 40-day half-life means a single missed dose has a tiny effect on overall blood levels.<\/p>\n<h3>Does Rtqs 200 cause weight gain?<\/h3>\n<p>No. Hydroxychloroquine is weight-neutral and slightly improves insulin sensitivity in patients with type 2 diabetes.<\/p>\n<h3>Is hydroxychloroquine the same as chloroquine?<\/h3>\n<p>Closely related but not identical. Hydroxychloroquine has an extra hydroxyl group that gives it a substantially better retinal-toxicity profile (~ 40 % less retinotoxic at equivalent doses) and better tolerability. For autoimmune disease, hydroxychloroquine is preferred over chloroquine. For malaria treatment in chloroquine-sensitive areas, both work.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2>Other Malaria Tablets<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/hcqs\/\"><strong>HCQS 200\/400 mg<\/strong><\/a> \u2014 Cipla hydroxychloroquine \u2014 200 mg and 400 mg strengths<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/hqcheal\/\"><strong>Hqcheal 200 mg<\/strong><\/a> \u2014 Healing Pharma hydroxychloroquine 200 mg<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/hqtor\/\"><strong>Hqtor 200 mg<\/strong><\/a> \u2014 Torrent Pharma hydroxychloroquine 200 mg<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/lariago\/\"><strong>Lariago 250 mg<\/strong><\/a> \u2014 Chloroquine \u2014 older 4-aminoquinoline, malaria-only use in chloroquine-sensitive areas<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/mefque\/\"><strong>Mefque 250 mg<\/strong><\/a> \u2014 Mefloquine \u2014 once-weekly chemoprophylaxis for chloroquine-resistant areas<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:24px 0;font-size:13px;line-height:1.6;\"><strong>Medisch disclaimer.<\/strong> This page is general information only and is not a substitute for travel-medicine advice or treatment under a clinician. Destination-specific drug-resistance patterns change \u2014 confirm prophylaxis choice against current <a href=\"https:\/\/wwwnc.cdc.gov\/travel\/yellowbook\/2024\/preparing\/malaria\" rel=\"nofollow noopener\" target=\"_blank\">CDC Yellow Book<\/a> of <a href=\"https:\/\/www.fitfortravel.nhs.uk\/destinations\" rel=\"nofollow noopener\" target=\"_blank\">fitfortravel.nhs.uk<\/a> guidance before travel. Any febrile illness within 1 year of travel to a malaria-endemic area warrants urgent thick-and-thin blood film. Severe malaria (impaired consciousness, jaundice, hypoglycaemia, respiratory distress) is a hospital emergency.<\/div>","protected":false},"excerpt":{"rendered":"<p>\u2705 Behandelt auto-immuunziekten<br \/>\n\u2705 Treats malaria effectively<br \/>\n\u2705 Vermindert ontsteking<br \/>\n\u2705 Verlicht gewrichtspijn<br \/>\n\u2705 Controls lupus symptoms<\/p>\n<p><strong>Rtqs<\/strong> bevat <strong>Hydroxychloroquine<\/strong>.<\/p>","protected":false},"featured_media":57566,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3141,3580,3448],"product_tag":[5301,4314,4328],"class_list":{"0":"post-57565","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-malaria-tablets","8":"product_cat-travel-health-category-overview","9":"product_tag-hcq","10":"product_tag-hydroxychloroquine","11":"product_tag-rtqs","13":"first","14":"instock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/57565","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=57565"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/57566"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=57565"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=57565"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=57565"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=57565"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}