{"id":57860,"date":"2024-02-27T18:05:01","date_gmt":"2024-02-27T18:05:01","guid":{"rendered":"https:\/\/medsname.com\/ketorol-dt\/"},"modified":"2026-05-01T10:49:14","modified_gmt":"2026-05-01T10:49:14","slug":"ketorol-dt","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/ketorol-dt\/","title":{"rendered":"Ketorol DT"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Ketorol DT?<\/h3>\n<p style=\"margin:0;\"><strong>Ketorol DT<\/strong> is een <strong>ketorolac tromethamine 10&nbsp;mg orally disintegrating tablet<\/strong> gedurende <strong>short-term<\/strong> relief of moderate to severe acute pain. Ketorolac is unusually potent for an oral NSAID and is often used as a <strong>non-opioid analgesic<\/strong> after surgery, dental procedures, renal colic, or significant soft-tissue injury. Usual dose: <strong>10&nbsp;mg every 4&ndash;6 hours with food, for a maximum of 5 days<\/strong>. Because of GI and renal risk, ketorolac is <strong>never used chronically<\/strong> &mdash; this is a short-course medicine only.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Wat u krijgt bij MedsBase:<\/strong> WHO-GMP gecertificeerde fabrikant \u00b7 Discrete verpakking \u00b7 Wereldwijde verzending \u00b7 1.400+ geverifieerde <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">klantbeoordelingen<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n<p><strong>Ketorol DT<\/strong> is an orally disintegrating tablet (DT) containing <strong>ketorolac tromethamine 10&nbsp;mg<\/strong> &mdash; the only NSAID in the world labelled solely for short-term, strong pain relief. Ketorolac&#8217;s analgesic potency is comparable to low-dose morphine for moderate pain, which has given it a particular role in post-operative, post-dental, and renal-colic care where strong analgesia is needed without the sedation, respiratory depression, or addiction risk of opioids.<\/p>\n<p>The orally disintegrating format dissolves on the tongue within seconds, making it useful when swallowing tablets is difficult &mdash; post-operative nausea, recent dental surgery, or heavy vomiting.<\/p>\n<h2 class=\"wp-block-heading\">What Is Ketorol DT Used For?<\/h2>\n<ul>\n<li><strong>Short-term management of moderate to severe acute pain<\/strong> &mdash; post-operative, post-partum, post-dental<\/li>\n<li><strong>Nierkoliek<\/strong> (kidney stone pain) &mdash; ketorolac is as effective as parenteral opioids in many studies<\/li>\n<li><strong>Biliary colic<\/strong><\/li>\n<li><strong>Acuut letsel aan het bewegingsapparaat<\/strong> &mdash; severe soft-tissue trauma<\/li>\n<li><strong>Primaire dysmenorroe<\/strong> &mdash; severe period pain unresponsive to first-line NSAIDs<\/li>\n<li><strong>Acute migraine<\/strong> &mdash; second-line; particularly when triptans are contraindicated<\/li>\n<\/ul>\n<p>Ketorolac is <strong>not indicated for minor or chronic pain<\/strong>. Using it for conditions where paracetamol or ibuprofen would be adequate unnecessarily exposes the patient to GI and renal risk.<\/p>\n<h2 class=\"wp-block-heading\">How Does Ketorolac Work?<\/h2>\n<p>Ketorolac is a <strong>niet-selectieve NSAID<\/strong> \u2014 het blokkeert zowel <strong>COX-1<\/strong> (die het maagslijmvlies, de bloedplaatjesfunctie en de nierdoorbloeding in stand houdt) en <strong>COX-2<\/strong> (die opgereguleerd wordt bij ontstekingshaarden). Deze brede werking verklaart zowel het sterke ontstekingsremmende effect als het bekende maag-darm- en nierbijwerkingsprofiel.<\/p>\n<p>De therapeutische keten van gebeurtenissen is hetzelfde voor elke NSAID:<\/p>\n<ol>\n<li>Weefselbeschadiging of ontsteking geeft fosfolipiden vrij uit celmembranen<\/li>\n<li>Fosfolipase A\u2082 zet deze om in arachidonzuur<\/li>\n<li>Cyclo-oxygenase (COX-1\/COX-2) zet arachidonzuur om in <strong>prostaglandinen<\/strong> \u2014 de moleculen die verantwoordelijk zijn voor pijn, zwelling en koorts<\/li>\n<li>Ketorolac blocks the COX enzymes, so less prostaglandin is produced, so there is less pain and inflammation<\/li>\n<\/ol>\n<p>Omdat prostaglandinen ook het maagslijmvlies beschermen, de nierdoorbloeding reguleren en de bloedplaatjesfunctie be\u00efnvloeden, is hetzelfde mechanisme dat pijn verlicht ook verantwoordelijk voor de belangrijkste bijwerkingen van NSAID's: maagirritatie, vochtretentie, hoge bloeddruk en (bij sommige personen) nierbelasting.<\/p>\n<h2 class=\"wp-block-heading\">Ketorol DT Dosing<\/h2>\n<ul>\n<li><strong>Oraal:<\/strong> 10&nbsp;mg every 4&ndash;6 hours as needed, maximum 40&nbsp;mg\/day<\/li>\n<li><strong>Maximum total duration (all routes combined):<\/strong> 5 dagen<\/li>\n<li><strong>Elderly (&gt; 65), body weight &lt; 50&nbsp;kg, or mild renal impairment:<\/strong> maximum 40&nbsp;mg\/day and total duration ideally \u2264 2&ndash;3 days<\/li>\n<\/ul>\n<p><strong>Do not exceed 5 days of continuous ketorolac therapy<\/strong> in any form. The risk of GI ulcer and kidney injury rises sharply beyond this window. Transition to an alternative analgesic (ibuprofen, diclofenac, or paracetamol) after day 5.<\/p>\n<p><strong>Hoe in te nemen:<\/strong> place the DT tablet on the tongue, allow it to disintegrate (5&ndash;15 seconds), swallow with saliva. No water needed. Take with food or milk when possible.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:16px 0;border-radius:4px;\">\n<p style=\"margin:0;\"><strong>Maag-darmveiligheid \u2014 lees dit voor de eerste dosis.<\/strong> Every NSAID, including Ketorol DT, carries a real risk of gastritis, peptic ulcer, and upper-GI bleeding. The risk is highest in patients over 65, in those with prior ulcer disease, and in anyone also taking low-dose aspirin, corticosteroids, SSRIs, or anticoagulants. Take Ketorol DT <em>met voedsel<\/em>, in, gebruik de <em>laagst effectieve dosis voor de kortst mogelijke tijd<\/em>, en overleg met uw arts over het voorschrijven van een protonpompremmer (omeprazol, pantoprazol) als u het langer dan 2\u20134 weken nodig heeft.<\/p>\n<\/div>\n<p><strong>Ketorolac-specific warnings:<\/strong> Because ketorolac is unusually potent per milligram, it carries a higher rate of GI ulcers, bleeds, and acute kidney injury than most other oral NSAIDs at comparable pain-relief doses. This is why the 5-day limit exists and must be observed.<\/p>\n<h2 class=\"wp-block-heading\">Who Should Not Take Ketorol DT?<\/h2>\n<ul>\n<li>Known hypersensitivity to Ketorolac or any NSAID<\/li>\n<li>Actieve of terugkerende maagzweer, maag-darmbloeding of maag-darmperforatie<\/li>\n<li>Astma, netelroos of neusontsteking veroorzaakt door aspirine of een andere NSAID (\u201caspirine-ge\u00efnduceerde luchtwegziekte\u201d)<\/li>\n<li>Ernstig hartfalen (NYHA klasse IV)<\/li>\n<li>Ernstige leverinsuffici\u00ebntie (Child\u2013Pugh C)<\/li>\n<li>Ernstige nierinsuffici\u00ebntie (CrCl &lt; 30 ml\/min)<\/li>\n<li>Derde trimester van de zwangerschap (risico op voortijdige sluiting van de ductus arteriosus en oligohydramnion)<\/li>\n<li>Recentelijke coronaire bypassoperatie (CABG) \u2014 absolute contra-indicatie voor alle NSAID's<\/li>\n<\/ul>\n<p><strong>Ketorolac-specific:<\/strong><\/p>\n<ul>\n<li>Suspected or actual cerebrovascular bleeding, haemorrhagic diathesis, incomplete haemostasis<\/li>\n<li>Current, recent, or high-risk GI ulcer or bleeding<\/li>\n<li>Concurrent use of other NSAIDs or aspirin<\/li>\n<li>Concurrent use of pentoxifylline or probenecid<\/li>\n<li>Volume depletion &mdash; correct first<\/li>\n<li>Labour and delivery (inhibits uterine contractions, may delay parturition)<\/li>\n<li>Paediatric use in most jurisdictions<\/li>\n<\/ul>\n<h3 class=\"wp-block-heading\">Cardiovasculair risico<\/h3>\n<p>Alle NSAID's (behalve lage doses aspirine) brengen een verhoogd risico op hartaanval en beroerte met zich mee en kunnen hartfalen verergeren. Het risico is afhankelijk van de dosis en duur en is over het algemeen het hoogst bij COX-2-selectieve middelen en bij diclofenac. Pati\u00ebnten met vastgestelde ischemische hartziekte, perifeer arterieel vaatlijden, beroerte of ongecontroleerde hypertensie moeten niet-selectieve NSAID's (ibuprofen of naproxen) gebruiken in de laagst effectieve dosis, of waar mogelijk paracetamol gebruiken in plaats daarvan.<\/p>\n<h3 class=\"wp-block-heading\">Nierveiligheid<\/h3>\n<p>NSAID's verminderen de productie van renale prostaglandinen, wat kan leiden tot zout- en waterretentie, verhoging van de bloeddruk en - bij kwetsbare pati\u00ebnten - acuut nierletsel. Hoogrisicogroepen zijn ouderen, pati\u00ebnten die ACE-remmers\/ARB's plus diuretica gebruiken (de \u201ctriple whammy\u201d), iedereen die uitgedroogd is (braken, diarree, hitte, zware inspanning) en mensen met reeds bestaande chronische nierziekte. Stop het NSAID en raadpleeg een arts als u verminderde urineproductie, zwelling of onverklaarbare gewichtstoename ontwikkelt.<\/p>\n<h2 class=\"wp-block-heading\">Side Effects of Ketorol DT<\/h2>\n<ul>\n<li><strong>Vaak voorkomend:<\/strong> nausea, dyspepsia, abdominal pain, diarrhoea, headache, dizziness, drowsiness, sweating<\/li>\n<li><strong>Zeldzaam maar belangrijk:<\/strong> peptic ulcer, GI bleeding, acute kidney injury (especially in volume-depleted or elderly patients), hypertension, elevated liver enzymes<\/li>\n<li><strong>Zeldzaam:<\/strong> severe hepatotoxicity, bronchospasm, Stevens-Johnson syndrome, anaphylaxis<\/li>\n<\/ul>\n<p>Stop Ketorol DT immediately and seek medical care for: signs of GI bleeding (black tarry stools, coffee-ground vomit, severe abdominal pain), reduced urine output, facial swelling or breathing difficulty, or a widespread rash.<\/p>\n<h2 class=\"wp-block-heading\">Ketorol DT vs Ketanov Injection<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;\">Product<\/th>\n<th style=\"padding:8px;text-align:left;\">Toedieningsweg<\/th>\n<th style=\"padding:8px;text-align:left;\">Typical dose<\/th>\n<th style=\"padding:8px;text-align:left;\">Werkingsbegin<\/th>\n<th style=\"padding:8px;text-align:left;\">Gebruik<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;\"><strong>Ketorol DT 10 mg<\/strong><\/td>\n<td style=\"padding:8px;\">Oral (DT)<\/td>\n<td style=\"padding:8px;\">10 mg q4&ndash;6 h<\/td>\n<td style=\"padding:8px;\">20&ndash;40 min<\/td>\n<td style=\"padding:8px;\">Moderate pain, home use, step-down from injection<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;\">Ketanov Injection 30 mg\/ml<\/td>\n<td style=\"padding:8px;\">IM or IV<\/td>\n<td style=\"padding:8px;\">30 mg q6 h (IM)<\/td>\n<td style=\"padding:8px;\">10&ndash;30 min<\/td>\n<td style=\"padding:8px;\">Severe acute pain, in-hospital, ED, peri-operative<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Total ketorolac exposure from any combination of routes must not exceed 5 days.<\/p>\n<h2 class=\"wp-block-heading\">Bestellen &amp; Levering<\/h2>\n<p>MedsBase biedt wereldwijde verzending voor elke bestelling. Bestellingen worden verzonden in discrete verpakkingen en arriveren in verpakkingen van de fabrikant. Als uw voorkeurssterkte of verpakkingsgrootte niet op voorraad is, neem dan contact op met de klantenservice voor een leverdatum.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:20px 0;border-radius:4px;\">\n<p style=\"margin:0;\"><strong>Medisch disclaimer.<\/strong> De informatie op deze pagina is alleen bedoeld voor algemene educatie. Het is geen vervanging voor advies van uw eigen arts of apotheker. NSAID's hebben goed gedocumenteerde gastro-intestinale, cardiovasculaire en renale risico's - overleg met een gekwalificeerde zorgverlener voordat u met, stopt of verandert van therapie, vooral als u een voorgeschiedenis heeft van maagzweer, hartaandoeningen, nieraandoeningen, astma of zwanger bent.<\/p>\n<\/div>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3 class=\"wp-block-heading\">What is Ketorol DT used for?<\/h3>\n<p>Ketorol DT (ketorolac 10&nbsp;mg orally disintegrating) is used for short-term relief of moderate to severe acute pain &mdash; post-operative, post-dental, renal colic, severe musculoskeletal injury, and severe dysmenorrhoea. Maximum 5 days.<\/p>\n<h3 class=\"wp-block-heading\">Why is ketorolac limited to 5 days?<\/h3>\n<p>Ketorolac is unusually potent per milligram, which also means unusually high risk of GI ulcer, bleeding, and acute kidney injury with prolonged use. Regulatory labelling and clinical evidence both limit continuous therapy to 5 days.<\/p>\n<h3 class=\"wp-block-heading\">Is Ketorol DT as strong as morphine?<\/h3>\n<p>At equivalent analgesic doses, ketorolac 10&nbsp;mg orally is comparable to low-dose morphine for moderate pain in post-operative studies. It does not cause sedation, respiratory depression, or addiction, which is why it is useful as an opioid-sparing analgesic.<\/p>\n<h3 class=\"wp-block-heading\">How fast does Ketorol DT work?<\/h3>\n<p>Onset of pain relief is usually 20&ndash;40 minutes after dissolving on the tongue. Peak effect at 1 hour. Duration of a single dose is about 4&ndash;6 hours.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Ketorol DT with paracetamol?<\/h3>\n<p>Yes. Ketorolac and paracetamol work on different pathways and are commonly combined for stronger acute pain relief. This is a standard post-operative strategy.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Ketorol DT with another NSAID?<\/h3>\n<p>No &mdash; this combination sharply raises GI bleed and kidney-injury risk. If you are on low-dose aspirin for cardioprotection, discuss with your doctor before starting ketorolac.<\/p>\n<h3 class=\"wp-block-heading\">How do I take the orally disintegrating tablet?<\/h3>\n<p>Place the tablet on your tongue, let it dissolve in 5&ndash;15 seconds, and swallow with saliva. No water is needed. Take with food or milk when possible.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol while on Ketorol DT?<\/h3>\n<p>No. Alcohol with ketorolac greatly increases the risk of GI bleeding. Avoid alcohol throughout the course.<\/p>\n<h3 class=\"wp-block-heading\">Is Ketorol DT safe in pregnancy?<\/h3>\n<p>No &mdash; particularly in the third trimester (risk of premature ductus arteriosus closure). In early pregnancy, paracetamol or morphine-equivalent analgesia is preferred over ketorolac.<\/p>\n<h3 class=\"wp-block-heading\">What happens if I take Ketorol DT for more than 5 days?<\/h3>\n<p>Each additional day of continuous therapy raises the risk of GI ulcer, kidney injury, and hypertension. If pain persists, switch to ibuprofen, diclofenac, paracetamol, or a medical review &mdash; do not simply keep taking ketorolac.<\/p>\n<h3 class=\"wp-block-heading\">What is the difference between Ketorol DT and Ketanov Injection?<\/h3>\n<p>Same molecule (ketorolac), different route. Ketorol DT is oral. Ketanov Injection is intramuscular or intravenous &mdash; faster onset, typically for inpatient or emergency use. Total ketorolac time (oral + injection combined) must not exceed 5 days.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Gerelateerde alternatieven<\/h3>\n<p>Andere producten in <strong>Chronische aandoeningen<\/strong> die klanten ook bekijken:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/bencid\/\">Bencid<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/calaptin-sr\/\">Calaptin SR<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/trajenta-duo\/\">Trajenta Duo<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/solu-medrol\/\">Solu-Medrol<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/meftal-p\/\">Meftal-P<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Fast pain relief<br \/>\n\u2705 Dissolvable tablets<br \/>\n\u2705 Makkelijk toe te dienen<br \/>\n\u2705 Ontstekingsremmende eigenschappen<br \/>\n\u2705 Effective analgesic<\/p>\n<p>Ketorol DT contains Ketorolac.<\/p>","protected":false},"featured_media":57861,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3555],"product_tag":[4372,4370],"class_list":{"0":"post-57860","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-pain-relief-medication","9":"product_tag-ketorol-dt","10":"product_tag-ketorolac","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/57860","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=57860"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/57861"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=57860"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=57860"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=57860"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=57860"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}