{"id":57866,"date":"2024-02-27T18:05:05","date_gmt":"2024-02-27T18:05:05","guid":{"rendered":"https:\/\/medsname.com\/kojiglo-gel\/"},"modified":"2026-05-01T10:49:14","modified_gmt":"2026-05-01T10:49:14","slug":"kojiglo-gel","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/kojiglo-gel\/","title":{"rendered":"Kojiglo Gel"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Kojiglo Gel?<\/h3>\n<p style=\"margin:0;\"><strong>Kojiglo Gel<\/strong> is een <strong>kojic acid 2%<\/strong> topical depigmenting gel from Glenmark, used for <strong>melasma<\/strong>, <strong>post-inflammatoire hyperpigmentatie (PIH)<\/strong>, <strong>solar lentigines (sun spots)<\/strong>, and other forms of skin hyperpigmentation. Kojic acid is a <strong>natural fungal metabolite that inhibits tyrosinase<\/strong> &mdash; the rate-limiting enzyme in melanin synthesis &mdash; producing gradual, uniform skin lightening over 8&ndash;12 weeks. Apply a thin film to dark patches <strong>een of twee keer per dag<\/strong>; daily broad-spectrum SPF 50+ in the morning is essential to maintain results. Kojic acid is a <strong>gentler alternative to hydroquinone<\/strong> &mdash; suitable for patients sensitive to hydroquinone, those wanting to avoid the FDA restriction on OTC hydroquinone, or those wanting a maintenance therapy after a hydroquinone or Kligman-triple cycle. <strong>Meest voorkomende bijwerkingen:<\/strong> mild irritation, contact dermatitis (3&ndash;5% of users) &mdash; patch-test before facial use.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Wat u krijgt bij MedsBase:<\/strong> WHO-GMP gecertificeerde fabrikant \u00b7 Discrete verpakking \u00b7 Wereldwijde verzending \u00b7 1.400+ geverifieerde <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">klantbeoordelingen<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n<h2 class=\"wp-block-heading\">What Is Kojiglo Gel?<\/h2>\n<p>Kojiglo Gel is a topical depigmenting gel from Glenmark containing <strong>kojic acid 2%<\/strong>. It comes in a 20 g tube. Kojic acid (5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one) is a natural compound originally isolated from <em>Aspergillus oryzae<\/em>, the fungus used to produce sake and soy sauce in traditional Japanese fermentation. It has been used as a topical depigmenting agent in dermatology since the 1980s and is widely available globally either as prescription-strength preparations or in over-the-counter cosmeceuticals.<\/p>\n<h2 class=\"wp-block-heading\">How Does Kojic Acid Work?<\/h2>\n<p>Kojic acid produces skin lightening through three complementary mechanisms:<\/p>\n<ul>\n<li><strong>Tyrosinaseremming<\/strong> &mdash; kojic acid chelates the copper at the active site of tyrosinase, the rate-limiting enzyme in melanin biosynthesis. Less tyrosinase activity means less melanin produced by melanocytes.<\/li>\n<li><strong>Antioxidant activity<\/strong> &mdash; kojic acid scavenges free radicals generated by UV exposure, indirectly reducing UV-driven melanocyte stimulation.<\/li>\n<li><strong>Mild antibacterial and antifungal activity<\/strong> &mdash; useful in patients whose hyperpigmentation is associated with low-grade inflammatory skin conditions.<\/li>\n<\/ul>\n<p>Compared to hydroquinone (the reference depigmenting agent), kojic acid is approximately <strong>10-times less potent<\/strong> on a per-percent basis &mdash; but better tolerated, with a much lower rate of contact dermatitis and effectively zero risk of exogenous ochronosis (the irreversible blue-grey discolouration that limits long-term hydroquinone use).<\/p>\n<p>Visible lightening typically appears at <strong>4\u20138 weken<\/strong>; piekeffect bereikt na <strong>Is Cabgolin hetzelfde als Dostinex?<\/strong> of consistent daily use plus rigorous SPF.<\/p>\n<h2 class=\"wp-block-heading\">Toepassingen en Indicaties<\/h2>\n<ul>\n<li><strong>Melasma (chloasma)<\/strong> &mdash; symmetric brown patches on cheeks, forehead, upper lip, often hormonally driven; particularly useful for sensitive-skin patients who don&#8217;t tolerate hydroquinone<\/li>\n<li><strong>Post-inflammatoire hyperpigmentatie (PIH)<\/strong> after acne, eczema, or burns &mdash; especially on Fitzpatrick III&ndash;VI skin where PIH is most prominent<\/li>\n<li><strong>Zonne-lentigines (zonnevlekken, ouderdomsvlekken)<\/strong><\/li>\n<li><strong>Sproeten (epheliden)<\/strong> &mdash; modest effect<\/li>\n<li><strong>Maintenance therapy after a hydroquinone or Kligman-triple cycle<\/strong> &mdash; gentler than HQ for indefinite use<\/li>\n<li><strong>Zwangerschap en borstvoeding<\/strong> &mdash; commonly used as the safer depigmenting choice when HQ is contraindicated (although topical retinoids must still be avoided)<\/li>\n<\/ul>\n<p>Kojiglo Gel is <strong>niet<\/strong> for: deep dermal-pigment melasma (laser or chemical peel), broken or eczematous skin, or as a substitute for sun protection.<\/p>\n<h2 class=\"wp-block-heading\">Kojiglo Gel Dosage and How to Apply<\/h2>\n<p>Kojiglo Gel comes in a 20 g tube at 2% kojic acid.<\/p>\n<h3 class=\"wp-block-heading\">How to Apply Kojiglo Gel Properly<\/h3>\n<ol>\n<li><strong>Was voorzichtig<\/strong> with a mild non-foaming cleanser, then pat dry. Wait 10&ndash;15 minutes.<\/li>\n<li><strong>Eerst een pleistertest uitvoeren<\/strong> &mdash; apply a small amount to the inner forearm for 24&ndash;48 hours before facial use. Kojic acid causes contact dermatitis in 3&ndash;5% of users.<\/li>\n<li><strong>Apply a thin film to the dark patches only<\/strong> &mdash; not to the entire face. Avoid surrounding healthy skin to prevent demarcation lines.<\/li>\n<li><strong>Avoid eyes, mouth corners, lips, mucous membranes, eyelids.<\/strong><\/li>\n<li><strong>Een of twee keer per dag<\/strong> &mdash; start at once daily (typically nightly), increase to twice daily if tolerated.<\/li>\n<li><strong>Daily broad-spectrum SPF 50+ in the morning is essential<\/strong> &mdash; UV exposure undoes kojic acid&#39;s effect within days. Reapply every 2&ndash;3 hours outdoors. Wide-brimmed hat. Avoid tanning beds entirely.<\/li>\n<li><strong>Behandelduur<\/strong> &mdash; kojic acid can be used continuously for 3&ndash;6 months, then a break of 4&ndash;8 weeks before resuming. Long-term use is generally acceptable but maintenance is best done with intermittent rather than continuous application.<\/li>\n<li><strong>Stop onmiddellijk als<\/strong> persistent stinging, contact dermatitis, or rebound darkening develops.<\/li>\n<\/ol>\n<h2 class=\"wp-block-heading\">Side Effects of Kojiglo Gel<\/h2>\n<p><strong>Common (mild, settles in 1&ndash;2 weeks):<\/strong><\/p>\n<ul>\n<li>Mild stinging, burning, or tingling on application &mdash; especially in the first week<\/li>\n<li>Erythema (mild redness) of treated areas<\/li>\n<li>Mild dryness or peeling<\/li>\n<li>Mild photosensitivity &mdash; emphasises the SPF-50+ rule<\/li>\n<\/ul>\n<p><strong>Minder vaak maar belangrijk:<\/strong><\/p>\n<ul>\n<li><strong>Contactdermatitis<\/strong> (3&ndash;5% of users) &mdash; eczematous reaction at the application site. Stop and switch agent.<\/li>\n<li>Persistent erythema or post-inflammatory hyperpigmentation paradoxically caused by irritation &mdash; reduce frequency or stop temporarily<\/li>\n<\/ul>\n<p>Unlike hydroquinone, kojic acid does <strong>not cause exogenous ochronosis<\/strong> (the irreversible blue-grey discolouration). This is its major safety advantage for long-term use.<\/p>\n<h2 class=\"wp-block-heading\">Contra-indicaties en waarschuwingen<\/h2>\n<ul>\n<li><strong>Hypersensitivity to kojic acid<\/strong><\/li>\n<li>Active eczema, dermatitis, or broken skin in the area to be treated &mdash; treat the inflammation first<\/li>\n<li>Active herpes labialis (cold sores) &mdash; defer until resolved<\/li>\n<li><strong>Children &lt;12<\/strong> &mdash; not generally indicated; if needed, paediatric dermatology supervision<\/li>\n<li><strong>Zwangerschap en borstvoeding<\/strong> &mdash; topical kojic acid has minimal systemic absorption and is generally considered safe; commonly used as the depigmenting agent of choice when hydroquinone is contraindicated<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Geneesmiddelinteracties<\/h2>\n<p>Topical kojic acid has minimal systemic absorption and no clinically significant systemic drug interactions. Local interactions to manage:<\/p>\n<ul>\n<li><strong>Other topical depigmenting agents<\/strong> (hydroquinone, arbutin, tretinoin, azelaic acid) &mdash; can be combined under dermatologist guidance for synergistic effect, but increase irritation risk; introduce one at a time<\/li>\n<li><strong>Topicale retino\u00efden<\/strong> (tretinoin, adapalene, tazarotene) &mdash; commonly combined; apply at separate times of day (retinoid evening, kojic acid morning) to minimise irritation<\/li>\n<li><strong>Chemical peels and microdermabrasion<\/strong> &mdash; pause kojic acid for 1&ndash;2 weeks before and after to reduce risk of post-procedure irritation<\/li>\n<li><strong>SPF \/ sunscreens<\/strong> &mdash; mandatory companion product<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">How Kojiglo Gel Compares to Alternatives<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Middel<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Potentie<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Opvallend kenmerk<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>Kojic acid 2% (Kojiglo Gel)<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Mild&ndash;moderate<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Gentler than HQ; safe long-term; no ochronosis risk<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\"><a href=\"https:\/\/medsbase.com\/nl\/eukroma-cream\/\">Hydroquinone 4% (Eukroma)<\/a><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Strong (gold standard)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">FDA-restricted (specialist use); 4&ndash;6 month max; ochronosis risk<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\"><a href=\"https:\/\/medsbase.com\/nl\/melacare-cream\/\">Kligman triple (Melacare, Triluma)<\/a><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Strongest<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">HQ + tretinoin + steroid; for moderate&ndash;severe melasma; 8-on\/8-off cycling<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\"><a href=\"https:\/\/medsbase.com\/nl\/eukroma-kj-cream\/\">HQ + Kojic combo (Eukroma-KJ)<\/a><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Moderate&ndash;strong<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Combines HQ&#39;s potency with kojic&#39;s tolerability<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Azela\u00efnezuur 15\u201320%<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Matig<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Pregnancy-safe alternative; anti-inflammatory<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Niacinamide 4&ndash;5%<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Mild<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">OTC; very gentle; long-term cosmetic use<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 class=\"wp-block-heading\">Opslag en houdbaarheid<\/h2>\n<p>Store Kojiglo Gel below 25&deg;C in the original tube, away from direct sunlight (kojic acid is light-sensitive). Replace the cap tightly after each use. Keep out of reach of children. Use within the manufacturer-stated period after first opening (typically 6 months) or before the printed expiry date, whichever is sooner.<\/p>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3 class=\"wp-block-heading\">Is kojic acid safer than hydroquinone?<\/h3>\n<p>Yes &mdash; kojic acid is gentler, has a much lower rate of contact dermatitis, and effectively zero risk of exogenous ochronosis (the irreversible blue-grey discolouration that limits long-term hydroquinone use). The trade-off is that kojic acid is roughly 10&times; less potent on a per-percent basis &mdash; results take longer and are more modest. For mild-to-moderate melasma or PIH, kojic acid is often the right choice. For severe melasma, hydroquinone or Kligman-triple is more effective.<\/p>\n<h3 class=\"wp-block-heading\">Hoelang duurt het voordat ik resultaten zie?<\/h3>\n<p>Visible lightening typically appears at 4&ndash;8 weeks of consistent daily application plus rigorous SPF. Peak effect at 3&ndash;6 months. If there is no visible improvement at 12 weeks, switching to a stronger agent (HQ or Kligman triple under medical supervision) may be appropriate.<\/p>\n<h3 class=\"wp-block-heading\">Can I use Kojiglo Gel during pregnancy?<\/h3>\n<p>Topical kojic acid has minimal systemic absorption and is generally considered safe in pregnancy and breastfeeding. It is commonly used as the depigmenting agent of choice during pregnancy when hydroquinone (avoid in pregnancy) and topical retinoids (avoid in pregnancy) are contraindicated. Always confirm with your obstetrician or dermatologist before starting any topical treatment in pregnancy.<\/p>\n<h3 class=\"wp-block-heading\">Can I combine kojic acid with vitamin C or niacinamide?<\/h3>\n<p>Yes &mdash; kojic acid combines well with topical vitamin C (L-ascorbic acid 10&ndash;20%) and niacinamide (4&ndash;5%) for enhanced depigmenting and antioxidant effect. Apply at separate times to minimise pH-related interactions: vitamin C in the morning under SPF, niacinamide and kojic acid in the evening.<\/p>\n<h3 class=\"wp-block-heading\">Will kojic acid bleach my whole face if it touches healthy skin?<\/h3>\n<p>Kojic acid is well-targeted to active melanocyte sites &mdash; it lightens pigmented patches more effectively than normal-skin areas. Some lightening of normal surrounding skin can occur with prolonged extensive use, producing a slight demarcation around the treated patches. To minimise this, apply only to the dark patches, not to the entire face.<\/p>\n<h3 class=\"wp-block-heading\">Why do I need SPF if I am using kojic acid at night?<\/h3>\n<p>UV exposure stimulates melanocytes to produce more melanin, undoing kojic acid&#39;s effect within days. Without daily broad-spectrum SPF 50+, kojic acid (and any other depigmenting agent) is essentially powerless. SPF is not optional; it is the primary therapy &mdash; the depigmenting agent is the adjunct.<\/p>\n<h3 class=\"wp-block-heading\">Is Kojiglo Gel a permanent fix for melasma?<\/h3>\n<p>No depigmenting agent is a permanent fix for melasma &mdash; the underlying tendency to overproduce melanin remains. With consistent SPF, hormonal stability, and intermittent maintenance therapy, results can be sustained for years. Stopping treatment OR stopping SPF will gradually allow the melasma to return.<\/p>\n<h3 class=\"wp-block-heading\">Where can I order Kojiglo Gel online?<\/h3>\n<p>You can order Kojiglo Gel from MedsBase in standard pack sizes (20 g tube). Orders ship worldwide with discreet packaging.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:24px 0;border-radius:4px;\">\n<strong>\u2695 Medisch disclaimer.<\/strong> This page is for informational purposes only and does not replace medical advice from a qualified healthcare professional. Always consult your doctor or dermatologist before starting topical depigmenting therapy &mdash; underlying conditions (drug-induced hyperpigmentation, post-inflammatory pigment from a chronic dermatosis, dermal melanocytosis) require diagnosis and may not respond to topical agents alone. MedsBase does not provide diagnosis, prescription, or clinical recommendations.\n<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Gerelateerde alternatieven<\/h3>\n<p>Andere producten in <strong>Algemene gezondheid<\/strong> die klanten ook bekijken:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/himalaya-talekt-syp\/\">Himalaya Talekt SYP<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/depsol\/\">Depsol<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/grisoheal\/\">Grisoheal<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/doxt-sl\/\">Doxt-SL<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/flucos-gel\/\">Flucos Gel<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Verheldert de huidskleur<br \/>\n\u2705 Vermindert hyperpigmentatie<br \/>\n\u2705 Vermindert donkere vlekken<br \/>\n\u2705 Smoothens skin texture<br \/>\n\u2705 Contains Kojic Acid<\/p>\n<p>Kojiglo Gel contains Kojic Acid.<\/p>","protected":false},"featured_media":57867,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3642,3141,3342],"product_tag":[3669,4373],"class_list":{"0":"post-57866","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-beauty-skin-care","7":"product_cat-category-overview","8":"product_cat-general-health","9":"product_tag-kojic-acid","10":"product_tag-kojiglo-gel","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/57866","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=57866"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/57867"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=57866"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=57866"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=57866"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=57866"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}