{"id":57949,"date":"2024-02-27T18:09:12","date_gmt":"2024-02-27T18:09:12","guid":{"rendered":"https:\/\/medsname.com\/atarise\/"},"modified":"2026-04-30T10:24:19","modified_gmt":"2026-04-30T10:24:19","slug":"atarise","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/atarise\/","title":{"rendered":"Atarise"},"content":{"rendered":"

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\u26a1 Snel antwoord<\/h3>\n

Atarise (Hydroxyzine 10 \/ 25 mg) is a sedating first-generation antihistamine and centrally-acting anxiolytic. Used for short-term anxiety, pre-procedural sedation, allergic pruritus and urticaria, and as an antiemetic. Non-addictive \u2014 useful when benzodiazepines are inappropriate.<\/p>\n<\/div>\n

\nWat u krijgt bij MedsBase:<\/strong> WHO-GMP gecertificeerde fabrikant \u00b7 Discrete verpakking \u00b7 Wereldwijde verzending \u00b7 1.400+ geverifieerde klantbeoordelingen<\/a>\n<\/div>\n

\ud83d\udce6 Elke bestelling is gedekt door onze Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n

Waarom bestellen bij MedsBase<\/h3>\n

Atarise at MedsBase is supplied directly from a WHO-GMP certified manufacturer in plain, discreet packaging. Every order is covered by our Reshipment Assurance Policy<\/a> \u2014 20 werkdagen levertermijn of wij sturen kosteloos opnieuw \u2014 en komt in aanmerking voor ons klantenloyaliteitsprogramma<\/a>. Wereldwijde verzending is beschikbaar naar de meeste bestemmingen.<\/p>\n

What Atarise is and how it works<\/h2>\n

Atarise is a 10 \/ 25 mg hydroxyzine tablet supplied by Sun Pharma. Hydroxyzine is a piperazine first-generation antihistamine with strong central H1 antagonism, weak 5-HT2A antagonism, and modest anticholinergic activity. The H1 component crosses the blood-brain barrier well and is the basis for its sedating and anxiolytic effect.<\/p>\n

Hydroxyzine is one of the few non-benzodiazepine, non-barbiturate options for true PRN anxiety relief \u2014 onset within 30\u201360 minutes, duration 4\u20136 hours.<\/p>\n

Indicaties en dosering<\/h2>\n\n\n\n\n\n\n\n\n\n\n\n
Indicatie<\/th>\nVolwassen dosis<\/th>\nOpmerkingen<\/th>\n<\/tr>\n<\/thead>\n
Acute anxiety \/ agitation<\/td>\n25\u2013100 mg PO\/IM, may repeat q6h<\/td>\nMax 400 mg\/day<\/td>\n<\/tr>\n
Pruritus \/ urticaria<\/td>\n25 mg TID\u2013QID<\/td>\nMax 100 mg QID<\/td>\n<\/tr>\n
Pre-operative sedation<\/td>\n50\u2013100 mg 1 hour pre-op<\/td>\n\u2014<\/td>\n<\/tr>\n
Antiemetic<\/td>\n25\u2013100 mg IM<\/td>\nAdults only<\/td>\n<\/tr>\n
Insomnia (off-label)<\/td>\n25\u201350 mg HS<\/td>\nShort-term only<\/td>\n<\/tr>\n
Paediatric pruritus \/ sedation<\/td>\n0.5\u20131 mg\/kg\/dose q6h<\/td>\n\u2014<\/td>\n<\/tr>\n
Older adults (any indication)<\/td>\nstart 10\u201325 mg<\/td>\nQT and falls risk<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Belangrijke veiligheidsoverwegingen<\/h2>\n
\nQT prolongation \u2014 2015 EMA restriction<\/strong><\/p>\n

Hydroxyzine prolongs QT in a dose-dependent manner. The EMA restricted dosing in 2015: maximum 100 mg\/day in adults, 50 mg\/day in older adults, and 2 mg\/kg\/day in children<\/strong>. Avoid in known QT prolongation, hypokalaemia\/hypomagnesaemia, recent MI, uncompensated heart failure, and concurrent QT-prolonging drugs (azoles, macrolides, fluoroquinolones, methadone, ondansetron, antipsychotics). Pre-treatment ECG advised in older adults.<\/p>\n<\/div>\n

\nAnticholinergische belasting<\/strong><\/p>\n

Hydroxyzine has meaningful anticholinergic activity \u2014 particularly relevant in older adults (Beers Criteria potentially inappropriate medication). Avoid in narrow-angle glaucoma, BPH with retention, dementia, severe constipation. The American Geriatrics Society discourages first-generation antihistamines as PRN agents in older adults.<\/p>\n<\/div>\n

\nSedation and driving<\/strong><\/p>\n

Single-dose sedation can persist 6+ hours; avoid driving and operating machinery until tolerability is known. Particularly problematic in opioid-naive surgical patients on the day of discharge.<\/p>\n<\/div>\n

Veelvoorkomende bijwerkingen<\/h2>\n