{"id":58071,"date":"2024-02-27T18:16:05","date_gmt":"2024-02-27T18:16:05","guid":{"rendered":"https:\/\/medsname.com\/lox-10-spray\/"},"modified":"2026-05-25T06:58:23","modified_gmt":"2026-05-25T06:58:23","slug":"lox-10-spray","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/lox-10-spray\/","title":{"rendered":"Lox 10% Spray"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff9e6;border-left:4px solid #f5a623;padding:16px 20px;margin:16px 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;\">&#9889; Quick Answer &mdash; What is Lox 10% Spray?<\/h3>\n<p style=\"margin:0;\"><strong>Lox 10% Spray<\/strong> is een <strong>lidocaine 10% topical spray<\/strong> (50 ml metered-dose pump bottle) used for <strong>surface anaesthesia<\/strong> of skin and mucous membranes before minor procedures &mdash; dental work, IV cannulation, intubation, endoscopy, ENT procedures, cervical instrumentation and skin biopsies. Each actuation delivers approximately <strong>10 mg of lidocaine<\/strong>. Onset is <strong>1&ndash;3 minutes<\/strong>; duration <strong>30\u201360 minuten<\/strong>. <strong>Do not exceed 20 sprays (200 mg) in a single session<\/strong> for an adult, and keep total doses well below the 3 mg\/kg lidocaine limit. Not for use on broken skin, inflamed mucosa or infants under 2 &mdash; systemic absorption rises sharply. Off-label: some patients apply a measured dose to the glans penis to delay ejaculation; this carries partner-numbing and absorption risks and should be discussed with a clinician.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Wat u krijgt bij MedsBase:<\/strong> WHO-GMP gecertificeerde fabrikant \u00b7 Discrete verpakking \u00b7 Wereldwijde verzending \u00b7 1.400+ geverifieerde <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">klantbeoordelingen<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n<div style=\"background:#f4f8fb;border:1px solid #e0e0e0;padding:12px 18px;margin:0 0 24px 0;border-radius:4px;font-size:14px;text-align:center;\">\n<strong>\ud83d\udd12 Versleutelde Afrekenprocedure<\/strong> \u00b7 <strong>\ud83d\udcb3 Geverifieerde Betaalprocessor<\/strong> \u00b7 <strong>\ud83d\ude9a Wereldwijde Verzending<\/strong> \u00b7 <strong>\u2b50 4.9\/5 van 1.400+ klanten<\/strong>\n<\/div>\n<h2 class=\"wp-block-heading\">What Is Lox 10% Spray?<\/h2>\n<p>Lox 10% Spray is a <strong>10% lidocaine topical spray<\/strong> supplied as a 50 ml metered pump bottle by Neon Laboratories. Each <strong>metered actuation delivers approximately 10 mg of lidocaine<\/strong> as an aqueous\/ethanolic spray that rapidly coats skin or accessible mucosal surfaces. The same lidocaine 10% topical spray is sold as <strong>Xylocaine 10% Spray<\/strong> (AstraZeneca) in many countries and as generic alternatives globally.<\/p>\n<p>Lidocaine is the world&#39;s most widely used amide-type <strong>local anaesthetic<\/strong>. It is on the WHO List of Essential Medicines. At 10% concentration in a spray, its dominant clinical use is <strong>surface numbing of mucosal tissues and skin<\/strong> immediately before a brief, painful procedure. The spray format is preferred over a 2% gel when rapid coverage of a large area is needed (e.g. oropharynx before intubation) or where a fine liquid mist reaches angles that a gel cannot.<\/p>\n<p>Lox 10% Spray is <strong>niet<\/strong> the same as injectable lidocaine used for infiltration anaesthesia (dentist&#39;s syringe), nor the same as the cream forms (EMLA, ELA-Max) used for intact skin analgesia &mdash; those creams contain 2.5% lidocaine and need 30&ndash;60 minutes under occlusion to work. Surface spray takes only minutes but does not penetrate intact thick skin deeply enough for a full skin biopsy; it numbs the surface mucosa only.<\/p>\n<h2 class=\"wp-block-heading\">How Does Lox 10% Spray Work?<\/h2>\n<p>Lidocaine reversibly <strong>blocks voltage-gated sodium channels<\/strong> in nerve membranes. Without the sodium flux that triggers action potentials, pain signals cannot travel along the nerve &mdash; the area becomes numb until the drug diffuses away and is metabolised. Lidocaine preferentially blocks small, fast-firing pain fibres (A-delta and C) before larger motor fibres, which is why patients keep motor function in the treated area while losing sharp pain sensation.<\/p>\n<p>After topical application to mucosa, onset of numbing is <strong>1&ndash;3 minutes<\/strong>; peak effect at 5&ndash;10 minutes; duration <strong>30\u201360 minuten<\/strong>. Lidocaine is metabolised in the liver by CYP1A2 and CYP3A4 to MEGX and GX metabolites and excreted renally &mdash; plasma half-life is around 1.5&ndash;2 hours.<\/p>\n<h2 class=\"wp-block-heading\">Toepassingen en Indicaties<\/h2>\n<ul>\n<li><strong>Dentistry<\/strong> &mdash; surface numbing of gingiva before needle insertion for infiltration anaesthesia; minor periodontal instrumentation; scaling<\/li>\n<li><strong>Intubation and airway instrumentation<\/strong> &mdash; numbing of the oropharynx, tongue base and vocal cords before laryngoscopy, bronchoscopy, tracheal intubation or transoesophageal echo<\/li>\n<li><strong>Upper GI endoscopy<\/strong> &mdash; spray to oropharynx before scope passage<\/li>\n<li><strong>ENT procedures<\/strong> &mdash; anterior and posterior rhinoscopy, middle-ear examination, direct laryngoscopy, indirect laryngoscopy, removal of foreign bodies from ear\/nose<\/li>\n<li><strong>Gynaecology and urology<\/strong> &mdash; cervical instrumentation (IUD insertion, biopsy), urethral meatus spray before catheterisation or cystoscopy<\/li>\n<li><strong>Rectal procedures<\/strong> &mdash; proctoscopy, anoscopy (spray to anal verge only; not for deep rectal use)<\/li>\n<li><strong>IV cannulation<\/strong> &mdash; surface spray 1&ndash;2 minutes before needle in needle-phobic or paediatric patients (adjunctive to EMLA\/creams)<\/li>\n<li><strong>Dermatology<\/strong> &mdash; surface numbing before curettage of small lesions, electrocautery of skin tags, minor biopsies (thin lesions only)<\/li>\n<li><strong>Off-label for premature ejaculation<\/strong> &mdash; a measured dose applied to the glans penis 10&ndash;15 minutes before intercourse can delay ejaculation. Wipe residue before penetration to avoid partner numbing; use a condom. Discuss with a clinician; for persistent PE, dapoxetine is the licensed oral option.<\/li>\n<\/ul>\n<p>Lox 10% Spray is <strong>not appropriate<\/strong> for: infiltration anaesthesia (use injectable lidocaine), deep skin biopsies (surface spray does not penetrate thick skin), eye\/conjunctival use (specific ophthalmic products are needed), or wound irrigation (use injectable lidocaine or sterile saline).<\/p>\n<h2 class=\"wp-block-heading\">Lox 10% Spray Dosage<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Procedure \/ site<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Typical sprays<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Max single session (adult)<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Dental &mdash; single gingival site<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>1&ndash;2 sprays<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">20 sprays (200 mg)<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Oropharynx before intubation<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>3&ndash;5 sprays<\/strong> each on tonsillar pillars, posterior pharynx, tongue base<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">20 sprays<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Nasal procedure (per nostril)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>2&ndash;3 sprays<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">10 per nostril<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Urethral meatus before catheter<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>1&ndash;2 sprays<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">4 total<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Cervix (IUD, biopsy)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>2&ndash;4 sprays<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">6<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Children 2&ndash;12 years<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>Weight-based &mdash; max 3 mg\/kg total<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Calculate &mdash; e.g. 20 kg child = 60 mg max = 6 sprays<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>Adult maximum single session: 20 sprays (200 mg lidocaine).<\/strong> Do not exceed 3 mg\/kg of lidocaine total for any patient in any single session. In debilitated, elderly or hepatic-impaired patients, reduce to 50% of the usual dose.<\/p>\n<h3 class=\"wp-block-heading\">How to Use Lox 10% Spray Properly<\/h3>\n<ol>\n<li><strong>Shake the bottle gently<\/strong> and prime by holding it vertical and pressing the pump 1&ndash;2 times into a tissue or the air, away from the patient&#39;s face.<\/li>\n<li><strong>Hold the nozzle 5&ndash;10 cm from the target<\/strong>. Aim away from the patient&#39;s eyes &mdash; lidocaine on the cornea causes immediate severe stinging but is not dangerous.<\/li>\n<li><strong>Press the pump once per metered dose<\/strong>. Each actuation delivers ~10 mg. Count doses aloud or note them on paper to track total.<\/li>\n<li><strong>Wait 1&ndash;3 minutes<\/strong> for onset before beginning the procedure. Mucosa will look slightly blanched; patient should report loss of sharp-touch sensation.<\/li>\n<li><strong>Do not exceed the per-session maximum<\/strong> &mdash; track spray count, especially in long procedures.<\/li>\n<li><strong>Wipe the external nozzle<\/strong> after each use to avoid cross-contamination; ideally use a new dose each patient, or single-patient bottles in clinical settings.<\/li>\n<li>After the procedure, <strong>advise the patient not to eat or drink for 1 hour<\/strong> after oropharyngeal spray &mdash; the gag reflex is impaired and aspiration risk is real.<\/li>\n<\/ol>\n<h2 class=\"wp-block-heading\">Side Effects of Lox 10% Spray<\/h2>\n<p><strong>Common (usually transient):<\/strong><\/p>\n<ul>\n<li>Brief stinging or burning on application<\/li>\n<li>Bitter taste after oropharyngeal use<\/li>\n<li>Mild erythema at the application site<\/li>\n<li>Numbness persisting 30&ndash;60 minutes after the procedure<\/li>\n<li>Reduced gag reflex after oropharyngeal spray (1 hour NPO needed)<\/li>\n<\/ul>\n<p><strong>Minder vaak:<\/strong><\/p>\n<ul>\n<li>Contact dermatitis (amide hypersensitivity is rare; ester anaesthetic hypersensitivity is more common)<\/li>\n<li>Methaemoglobinaemia &mdash; particularly with high total dose, in infants, or with benzocaine co-application<\/li>\n<li>Dizziness, lightheadedness (early systemic toxicity sign)<\/li>\n<\/ul>\n<p><strong>Serious &mdash; Local Anaesthetic Systemic Toxicity (LAST), stop and treat:<\/strong><\/p>\n<ul>\n<li>Perioral numbness, metallic taste, tinnitus &mdash; earliest CNS signs<\/li>\n<li>Slurred speech, tremor, dysarthria &mdash; progression<\/li>\n<li>Seizures &mdash; mid-severity CNS toxicity<\/li>\n<li>Hypotension, bradycardia, arrhythmia &mdash; cardiovascular toxicity (very high doses)<\/li>\n<li>Cardiac arrest &mdash; if any of these develop, stop, support airway\/breathing\/circulation, and consider <strong>intralipid 20% IV<\/strong> (1.5 ml\/kg bolus then 0.25 ml\/kg\/min infusion)<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Waarschuwingen en voorzorgsmaatregelen<\/h2>\n<ul>\n<li><strong>Track total dose.<\/strong> Absolute maximum is 3 mg\/kg or 200 mg in an adult &mdash; whichever is lower. Count sprays.<\/li>\n<li><strong>Avoid broken skin, inflamed mucosa or traumatised tissue<\/strong> &mdash; absorption rises sharply and LAST becomes more likely.<\/li>\n<li><strong>Leverfunctiestoornis<\/strong> reduces lidocaine clearance &mdash; use half the usual dose.<\/li>\n<li><strong>Cardiac conduction disease<\/strong> (high-grade AV block, pacemaker dependency): use cautiously; lidocaine prolongs AV conduction.<\/li>\n<li><strong>Hartfalen<\/strong> reduces hepatic blood flow and clearance &mdash; halve the dose.<\/li>\n<li><strong>Elderly \/ debilitated:<\/strong> reduce to 50% dose; lidocaine plasma half-life is longer.<\/li>\n<li><strong>Infants and small children:<\/strong> calculate 3 mg\/kg max carefully. Avoid in infants under 2 except under anaesthetic supervision.<\/li>\n<li><strong>Post-oropharyngeal spray:<\/strong> 1 hour NPO (nothing by mouth) &mdash; aspiration risk.<\/li>\n<li><strong>Do not spray into the eye<\/strong> &mdash; severe irritation. Use ophthalmic lidocaine (0.5%) if eye anaesthesia needed.<\/li>\n<li><strong>Zwangerschap:<\/strong> FDA Category B &mdash; small topical doses are considered safe; discuss with obstetrician.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Contra-indicaties<\/h2>\n<ul>\n<li>Known hypersensitivity to lidocaine, other amide-type local anaesthetics, or any formulation excipient<\/li>\n<li>Second- or third-degree AV block (without pacemaker)<\/li>\n<li>Wolff-Parkinson-White syndrome (relative)<\/li>\n<li>Severe sinoatrial or intraventricular conduction disease<\/li>\n<li>Porphyria &mdash; lidocaine can precipitate an acute attack<\/li>\n<li>Infants under 2 years (relative; specialist-only decision)<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Geneesmiddelinteracties<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Interacting drug<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Effect<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Wat te doen<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Class I and III antiarrhythmics (mexiletine, amiodarone, quinidine)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Additive cardiac conduction slowing<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Reduce dose; ECG monitoring in cardiac patients<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Cimetidine, ranitidine<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Reduce hepatic clearance of lidocaine &mdash; higher plasma levels<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Halve dose; use alternate H2 blocker or PPI<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Beta-blockers (propranolol)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Reduced hepatic blood flow &mdash; slower lidocaine clearance<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor for early LAST signs<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">CYP3A4 inhibitors (ketoconazole, ritonavir, erythromycin)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Slowed lidocaine metabolism<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Reduce dose; monitor<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Other local anaesthetics (benzocaine, prilocaine)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Additive systemic toxicity; benzocaine adds methaemoglobinaemia risk<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Do not combine at maximal doses<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Dapsone, nitric-oxide donors, metoclopramide (high-dose)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Increase methaemoglobinaemia risk with lidocaine<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Caution; avoid stacking<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 class=\"wp-block-heading\">Opslag<\/h2>\n<ul>\n<li>Store below <strong>25&deg;C<\/strong> in a dry place.<\/li>\n<li>Keep the bottle upright to ensure the pump primes correctly.<\/li>\n<li>Do not expose to direct sunlight, flame or sparks &mdash; the propellant vehicle contains ethanol and is flammable.<\/li>\n<li>Discard 12 months after first opening.<\/li>\n<li>Keep out of reach of children.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Gerelateerde alternatieven op MedsBase<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/crocin-advance\/\"><strong>Crocin Advance (paracetamol 500 mg, fast-dispersing) &mdash; rapid-onset analgesic<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/meftal\/\"><strong>Meftal (mefenamic acid 250 \/ 500 mg) &mdash; NSAID for period pain and inflammation<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/hyloric\/\"><strong>Hyloric (allopurinol 100 \/ 300 mg) &mdash; gout prophylaxis<\/strong><\/a><\/li>\n<\/ul>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3 class=\"wp-block-heading\">Is Lox 10% Spray the same as Xylocaine 10% Spray?<\/h3>\n<p>Yes &mdash; the formulation (lidocaine 10% topical spray, ~10 mg per actuation, 50 ml bottle) is clinically interchangeable with <strong>Xylocaine 10% Spray<\/strong> (AstraZeneca) and other generic 10% lidocaine sprays worldwide. The drug, concentration and delivery method are identical.<\/p>\n<h3 class=\"wp-block-heading\">How long does Lox 10% Spray last?<\/h3>\n<p>Onset is <strong>1&ndash;3 minutes<\/strong>; full anaesthetic depth at 5&ndash;10 minutes; surface numbness persists <strong>30\u201360 minuten<\/strong>. For oropharyngeal use, the gag reflex remains impaired for around <strong>1 uur<\/strong> &mdash; do not eat or drink during that window to avoid aspiration.<\/p>\n<h3 class=\"wp-block-heading\">What is the maximum safe dose?<\/h3>\n<p><strong>3 mg\/kg of lidocaine, or 200 mg total, whichever is lower.<\/strong> For an adult that is <strong>20 sprays<\/strong> in a single session. For a 30 kg child, it is 90 mg \/ 9 sprays. Halve the dose in elderly, hepatic-impaired and cardiac-failure patients.<\/p>\n<h3 class=\"wp-block-heading\">Can I use Lox 10% Spray for premature ejaculation?<\/h3>\n<p>Some men apply a measured dose (1&ndash;2 sprays) to the glans penis 10&ndash;15 minutes before intercourse to delay ejaculation. This is off-label &mdash; efficacy is real but three practical issues matter: (1) residual lidocaine numbs the partner, so wipe thoroughly and use a condom; (2) do not exceed 2 sprays per use &mdash; more does not improve the effect but does increase LAST risk; (3) for persistent PE, <strong>dapoxetine<\/strong> (sold as Poxet, Priligy and Super Vilitra\/Super P-Force in combination with PDE5 inhibitors) is the licensed oral option with better sustained efficacy. Discuss with a clinician.<\/p>\n<h3 class=\"wp-block-heading\">Can Lox 10% Spray be used on children?<\/h3>\n<p>Yes, with care. Calculate maximum total dose as <strong>3 mg\/kg<\/strong> (one spray = 10 mg). For a 20 kg child the ceiling is 60 mg = 6 sprays in a single session. Avoid in infants under 2 except under anaesthetic supervision &mdash; the skin\/mucosa absorption in infants is higher and methaemoglobinaemia risk is greater.<\/p>\n<h3 class=\"wp-block-heading\">What are the first signs of lidocaine toxicity (LAST)?<\/h3>\n<p>The earliest CNS signs are <strong>perioral numbness, metallic taste, tinnitus, and lightheadedness<\/strong> &mdash; these develop within minutes of a high dose. If any appear, stop applying, call for help and place the patient in a safe position. Progression is to slurred speech, tremor, seizures, then cardiovascular collapse. Treatment is airway\/breathing\/circulation support and <strong>intralipid 20% IV<\/strong> in severe cases.<\/p>\n<h3 class=\"wp-block-heading\">Can Lox 10% Spray be used on open wounds?<\/h3>\n<p><strong>Nee.<\/strong> Absorption from broken skin or inflamed mucosa is far higher than from intact surfaces &mdash; systemic toxicity risk rises. For wound cleaning or small open lacerations, use injectable lidocaine for infiltration anaesthesia (different product).<\/p>\n<h3 class=\"wp-block-heading\">Is Lox 10% Spray safe during pregnancy?<\/h3>\n<p>Lidocaine is FDA Pregnancy Category B &mdash; small topical doses are widely considered safe during pregnancy (e.g. dental and obstetric use). Avoid high total doses and discuss with your obstetrician if used for any non-urgent procedure.<\/p>\n<h3 class=\"wp-block-heading\">Why does my spray sting when I first apply it?<\/h3>\n<p>Brief stinging is the expected <strong>initial irritation<\/strong> of the ethanolic vehicle before numbness sets in &mdash; it resolves within 1&ndash;2 minutes as the anaesthetic takes effect. Severe persistent pain, rash, swelling, or difficulty breathing after application is <strong>niet<\/strong> normal and may indicate an allergic reaction &mdash; stop use and seek medical review.<\/p>\n<p class=\"medsbase-link-boost-2026-05-04\" data-marker=\"mb-link-boost-lox-2-jelly\"><a href=\"https:\/\/medsbase.com\/nl\/lox-10-spray\/\">Lox 10% Spray<\/a> delivers fast surface numbing at high concentration, but for catheterisation, cystoscopy, or sustained PE-delay use that benefits from a sterile lubricating gel format, switch to <a href=\"https:\/\/medsbase.com\/nl\/lox-2-jelly\/\">Lox 2% Jelly (lidocaine 2% topical\/urethral)<\/a> \u2014 same lidocaine molecule, lower concentration, longer contact dwell.<\/p>\n<p class=\"medsbase-link-boost-2026-05-25\" data-marker=\"mb-link-boost-hynidase-injection\"><a href=\"https:\/\/medsbase.com\/nl\/lox-10-spray\/\">Lox 10% Spray<\/a> gives rapid mucosal lignocaine anaesthesia, and for deeper infiltration the same active is often paired with <a href=\"https:\/\/medsbase.com\/nl\/hynidase-injection\/\">Hynidase Injection (hyaluronidase 1500 IU)<\/a>, a spreading enzyme that helps the anaesthetic diffuse evenly across a wider tissue field.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Gerelateerde alternatieven<\/h3>\n<p>Andere producten in <strong>Chronische aandoeningen<\/strong> die klanten ook bekijken:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/conimune-me\/\">Conimune ME<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/simvotin\/\">Simvotin<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/trinicalm-plus\/\">Trinicalm Plus<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/flexabenz-er\/\">Flexabenz ER<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/robinax\/\">Robinax<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Fast-acting pain relief<br \/>\n\u2705 Lidocaine spray<br \/>\n\u2705 Topical application<br \/>\n\u2705 Local anesthesia<br \/>\n\u2705 Convenient to use<\/p>\n<p>Lox 10% Spray contains Lidocaine.<\/p>","protected":false},"featured_media":58072,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3555],"product_tag":[4412,4415],"class_list":{"0":"post-58071","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-pain-relief-medication","9":"product_tag-lidocaine","10":"product_tag-lox-10-spray","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/58071","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=58071"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/58072"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=58071"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=58071"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=58071"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=58071"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}