{"id":58470,"date":"2024-02-27T18:37:42","date_gmt":"2024-02-27T18:37:42","guid":{"rendered":"https:\/\/medsname.com\/montek-plus\/"},"modified":"2026-04-30T10:24:13","modified_gmt":"2026-04-30T10:24:13","slug":"montek-plus","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/montek-plus\/","title":{"rendered":"Montek Plus"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 28px 0;border-radius:4px;\">\n<h3 style=\"margin:0 0 10px 0;font-size:18px;color:#1a1a1a;\">\u26a1 Quick Answer \u2014 What is Montek Plus?<\/h3>\n<p><strong>Montek Plus<\/strong> bevat <strong>montelukast + levocetirizine<\/strong>, an oral preventer for asthma and allergic rhinitis. The combination delivers <strong>montelukast<\/strong> (a leukotriene receptor antagonist that blocks LTD4 mediator action) plus <strong>levocetirizine<\/strong> (a non-sedating second-generation H1 antihistamine). Used for allergy-driven asthma where rhinitis and bronchospasm coexist (the United Airways disease). Each tablet contains <strong>montelukast 10 mg + levocetirizine 5 mg<\/strong>, geproduceerd door <strong>Sun Pharma<\/strong>. Taken <strong>once daily in the evening<\/strong>.<\/p>\n<p><strong>Important \u2014 neuropsychiatric warning:<\/strong> the FDA added a black-box warning in 2020 noting reports of mood changes, sleep disturbance, anxiety, depression, and (rarely) suicidal ideation with montelukast. Discuss any new mood symptoms with your prescriber.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Wat u krijgt bij MedsBase:<\/strong> WHO-GMP gecertificeerde fabrikant \u00b7 Discrete verpakking \u00b7 Wereldwijde verzending \u00b7 1.400+ geverifieerde <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">klantbeoordelingen<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n<div style=\"background:#f4f8fb;border:1px solid #e0e0e0;padding:12px 18px;margin:0 0 24px 0;border-radius:4px;font-size:14px;text-align:center;\">\n<strong>\ud83d\udd12 Versleutelde afrekenprocedure<\/strong> \u00b7 <strong>\ud83d\udcb3 Geverifieerde betalingsverwerker<\/strong> \u00b7 <strong>\ud83d\ude9a Wereldwijde verzending<\/strong> \u00b7 <strong>\u2b50 4,9\/5 van 1.400+ klanten<\/strong>\n<\/div>\n<h2>What Is Montek Plus?<\/h2>\n<p>Montek Plus is a combination of montelukast (LTRA) and levocetirizine (antihistamine) manufactured by Sun Pharma at WHO-GMP certified facilities.  Available as 4 mg, 5 mg, and 10 mg tablets \u2014 strengths chosen by age and indication.<\/p>\n<h2>How Does Montek Plus Work?<\/h2>\n<ul>\n<li><strong>Montelukast<\/strong> selectively antagonises the CysLT1 receptor \u2014 preventing LTD4-mediated bronchoconstriction, eosinophil recruitment, mucus hypersecretion, and microvascular leak.<\/li>\n<li><strong>Levocetirizine<\/strong> (active R-isomer of cetirizine) blocks histamine H1 receptors with high selectivity \u2014 controls itching, sneezing, runny nose, and mild bronchospasm without significant sedation.<\/li>\n<li><strong>Combined<\/strong> the two molecules cover the leukotriene and histamine arms of the allergy cascade, giving more complete control of allergic asthma and rhinitis than either alone.<\/li>\n<\/ul>\n<h2>Toepassingen en Indicaties<\/h2>\n<ul>\n<li><strong>Persisterend astma<\/strong> \u2014 add-on preventer in patients not controlled by ICS alone (alternative to LABA or LAMA add-on)<\/li>\n<li><strong>Inspanningsastma<\/strong> \u2014 particularly effective; taken 2 hours before exercise<\/li>\n<li><strong>Aspirin-exacerbated respiratory disease (AERD)<\/strong> \u2014 leukotrienes are central to this phenotype<\/li>\n<li><strong>Allergische rhinitis<\/strong> \u2014 both seasonal (hay fever) and perennial<\/li>\n<li><strong>Allergic asthma with concomitant rhinitis<\/strong> \u2014 the combo addresses both compartments simultaneously<\/li>\n<li><strong>Chronische urticaria<\/strong> \u2014 montelukast as adjunct to high-dose antihistamine<\/li>\n<\/ul>\n<h2>Montek Plus Dosage<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Pati\u00ebnt<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Dosering<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Frequentie<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Adults &amp; children &gt;15 yr<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>1 tablet<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Once daily in the evening<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Children 6\u201314 yr (Montek Plus 5 strength)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>1 tablet (5 mg + 2.5 mg)<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Once daily in the evening<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Side Effects of Montek Plus<\/h2>\n<ul>\n<li>Hoofdpijn<\/li>\n<li>Lichte buikpijn of misselijkheid<\/li>\n<li>Sleep disturbance (vivid dreams, insomnia)<\/li>\n<li>Mood changes \u2014 irritability, anxiety, depression (FDA black-box warning, 2020)<\/li>\n<li>Mild drowsiness from levocetirizine in some users (less than first-generation antihistamines)<\/li>\n<li>Huiduitslag<\/li>\n<\/ul>\n<p><strong>Ernstig \u2014 stop en zoek hulp:<\/strong><\/p>\n<ul>\n<li>Ernstige allergische reactie \/ angio-oedeem<\/li>\n<li>Suicidal ideation or severe depression \u2014 STOP and seek urgent psychiatric review<\/li>\n<li>Churg-Strauss syndrome (eosinophilic vasculitis) \u2014 rare; suspect in ICS-tapering patients with new vasculitic features (rash, neuropathy, eosinophilia)<\/li>\n<li>Hepatitis (rare)<\/li>\n<\/ul>\n<h2>Waarschuwingen en voorzorgsmaatregelen<\/h2>\n<ul>\n<li><strong>Black-box warning \u2014 neuropsychiatric events.<\/strong> If new mood changes, anxiety, sleep disturbance, agitation, depression, or suicidal thoughts occur, stop Montek Plus and contact your prescriber.<\/li>\n<li><strong>Geen noodmedicatie.<\/strong> Do not use in acute asthma attacks \u2014 onset is too slow.<\/li>\n<li><strong>Ga door met ICS<\/strong> if previously prescribed; montelukast does not replace inhaled corticosteroids.<\/li>\n<li><strong>Leverfunctiestoornis:<\/strong> use cautiously in moderate-to-severe disease.<\/li>\n<li><strong>Zwangerschap en borstvoeding:<\/strong> reasonable safety data; use when benefits outweigh risks.<\/li>\n<li><strong>Kinderen<\/strong> may show increased risk of behavioural changes \u2014 counsel parents to monitor mood.<\/li>\n<\/ul>\n<h2>Contra-indicaties<\/h2>\n<ul>\n<li>Hypersensitivity to montelukast, levocetirizine, or excipients<\/li>\n<li>Severe hepatic impairment \u2014 relative<\/li>\n<li>Severe renal impairment \u2014 levocetirizine accumulates<\/li>\n<\/ul>\n<h2>Geneesmiddelinteracties<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Interagerend geneesmiddel<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Effect<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Wat te doen<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Phenobarbital, phenytoin, rifampicin<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Induce CYP enzymes \u2014 reduce montelukast levels<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor asthma control<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Gemfibrozil<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Inhibits CYP2C8 \u2014 increases montelukast levels<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Voorzichtig gebruiken<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Warfarine<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Theoretical INR change reported in case reports<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor INR after starting\/stopping<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Opslag<\/h2>\n<ul>\n<li>Bewaren beneden <strong>25\u00b0C<\/strong> op een koele, droge plaats uit direct zonlicht.<\/li>\n<li>Bewaar in de originele verpakking tot gebruik ter bescherming tegen vocht en licht.<\/li>\n<li>Niet gebruiken na de vervaldatum die op de strip staat vermeld.<\/li>\n<li>Buiten bereik van kinderen houden.<\/li>\n<\/ul>\n<h2>Gerelateerde alternatieven op MedsBase<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/asthalin-inhaler\/\"><strong>Asthalin Inhaler \u2014 salbutamol verlichter<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/budecort-inhaler\/\"><strong>Budecort Inhaler \u2014 budesonide ICS-preventer<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/foracort-inhaler\/\"><strong>Foracort Inhaler \u2014 budesonide + formoterol ICS-LABA<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/tiova-inhaler\/\"><strong>Tiova Inhaler \u2014 tiotropium LAMA voor COPD<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/montair\/\"><strong>Montair \u2014 montelukast LTRA-tablet<\/strong><\/a><\/li>\n<\/ul>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3>When should I take montelukast?<\/h3>\n<p>Once daily in the evening, with or without food. Evening dosing matches the typical overnight rise in leukotriene mediators and gives best protection against early-morning symptoms.<\/p>\n<h3>How long until montelukast works?<\/h3>\n<p>Some symptom relief within 24\u201348 hours. Full effect on asthma exacerbation rate develops over 4\u20138 weeks.<\/p>\n<h3>Should I worry about the FDA black-box warning?<\/h3>\n<p>The 2020 FDA black-box warning highlighted reports of mood changes, sleep disturbance, anxiety, depression, and rarely suicidal ideation \u2014 particularly in children. The absolute risk is low but real. Watch for any new mood symptoms in yourself or your child; stop the drug and contact your prescriber if they appear.<\/p>\n<h3>Can montelukast replace my inhaler?<\/h3>\n<p>No \u2014 montelukast is an add-on preventer. It does not replace inhaled corticosteroids (Budecort, Beclate, Foracort, Seretide). Continue ICS as prescribed.<\/p>\n<h3>Is montelukast a rescue medication?<\/h3>\n<p>No \u2014 onset is too slow. Use a SABA (Asthalin, Levolin) for acute attacks.<\/p>\n<h3>Can children take montelukast?<\/h3>\n<p>Yes from 6 months of age in age-appropriate strengths (4 mg granules, 4 mg or 5 mg chewable, 10 mg tablet). Counsel parents to monitor mood and behaviour.<\/p>\n<h3>Is montelukast safe in pregnancy?<\/h3>\n<p>Reasonable observational data; use when benefits outweigh risks, particularly in patients whose asthma is well-controlled on it.<\/p>\n<h3>Does montelukast help allergic rhinitis?<\/h3>\n<p>Yes \u2014 montelukast is licensed for both asthma and allergic rhinitis. Particularly useful when both coexist (United Airways disease).<\/p>\n<h3>Should I stop montelukast if I feel better?<\/h3>\n<p>No \u2014 continue daily for as long as your prescriber advises. Stopping leads to gradual return of symptoms over days-to-weeks.<\/p>\n<h3>When is the Montek Plus combination used?<\/h3>\n<p>When asthma and allergic rhinitis coexist (the United Airways disease). The fixed-dose combination simplifies the regimen \u2014 one tablet covers both leukotriene and histamine arms of the allergy cascade.<\/p>\n<h3>Will Montek Plus make me drowsy?<\/h3>\n<p>Levocetirizine is a non-sedating second-generation antihistamine \u2014 drowsiness is uncommon (about 5\u20137% in trials, less than cetirizine). The drowsiness, if any, is usually mild.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:24px 0;border-radius:4px;font-size:13px;\"><strong>Medische disclaimer:<\/strong> Deze pagina is educatief en vervangt geen professioneel medisch advies. Raadpleeg altijd een gekwalificeerde zorgverlener voordat u een inhaler of respiratoir medicijn start, stopt of wijzigt, vooral als u andere medische aandoeningen heeft, andere voorgeschreven medicijnen gebruikt, zwanger bent of borstvoeding geeft, of ouder bent dan 65.<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Gerelateerde alternatieven<\/h3>\n<p>Andere producten in <strong>Chronische aandoeningen<\/strong> die klanten ook bekijken:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/aerocort-inhaler\/\">Aerocort Inhaler<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/lodoz\/\">Lodoz<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/nicardia-retard\/\">Nicardia Retard<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/imutrex\/\">Imutrex<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/headset\/\">Headset<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Manages asthma<br \/>\n\u2705 Controls wheezing<br \/>\n\u2705 Reduces bronchoconstriction<br \/>\n\u2705 Eases breathing<br \/>\n\u2705 Prevents airway inflammation<\/p>\n<p>Montek Plus contains Montelukast &amp; Bambuterol.<\/p>","protected":false},"featured_media":58471,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3681,3141,3223],"product_tag":[3707,4498,4499],"class_list":{"0":"post-58470","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-asthma-copd-treatment","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","9":"product_tag-bambuterol","10":"product_tag-montek-plus","11":"product_tag-montelukast","13":"first","14":"instock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/58470","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=58470"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/58471"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=58470"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=58470"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=58470"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=58470"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}