{"id":58688,"date":"2024-02-28T05:23:07","date_gmt":"2024-02-28T05:23:07","guid":{"rendered":"https:\/\/medsname.com\/lupimeb\/"},"modified":"2026-05-07T07:15:50","modified_gmt":"2026-05-07T07:15:50","slug":"lupimeb","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/lupimeb\/","title":{"rendered":"Lupimeb"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"margin:0 0 22px;padding:16px 20px;background:#fff8e1;border-left:4px solid #f5a623;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px;font-size:18px;color:#2c3e50;\">Quick Answer &mdash; What is Lupimeb?<\/h3>\n<div style=\"margin:0;font-size:15px;line-height:1.55;color:#333;\">\n<p><strong>Lupimeb<\/strong> is een oraal <strong>mebendazole 100&nbsp;mg chewable tablet<\/strong> van <strong>Lupin<\/strong>. Mebendazole is a WHO Essential Medicine for <strong>pinworm, roundworm, hookworm, and whipworm<\/strong>. Standaard dosering voor volwassenen: <strong>100&nbsp;mg as a single dose for pinworm, repeat in 2 weeks<\/strong>. For mixed infection or whipworm: <strong>100&nbsp;mg twice daily for 3 days<\/strong>.<\/p>\n<\/div>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"margin:24px 0;padding:14px 18px;background:#f4f4f4;border:1px solid #e1e1e1;border-radius:4px;font-size:14px;color:#444;line-height:1.55;\"><strong>Waarom bestellen bij MedsBase:<\/strong> \u2713 Afkomstig van <strong>WHO-GMP gecertificeerde fabrikanten<\/strong> \u00b7 \u2713 Discrete verpakking \u00b7 \u2713 Wereldwijde verzending \u00b7 \u2713 <strong>1.400+ klantbeoordelingen<\/strong> op <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">medsbase.com\/reviews<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n<h2 class=\"wp-block-heading\">What is Lupimeb?<\/h2>\n<p><strong>Lupimeb<\/strong> is mebendazole 100&nbsp;mg chewable from <strong>Lupin<\/strong>. Mebendazole was the first benzimidazole anthelmintic in routine human use and remains a WHO Essential Medicine. Albendazole has overtaken it as first-line in most settings, but mebendazole has a niche role: it is preferred in patients with concurrent moderate-to-severe hepatic impairment (less hepatic metabolism) and is the agent of choice in some paediatric whipworm protocols.<\/p>\n<h2 class=\"wp-block-heading\">Werkingsmechanisme<\/h2>\n<p>Mebendazole binds <strong>\u03b2-tubuline<\/strong> in parasite cells, preventing microtubule polymerisation. This blocks parasite glucose uptake and depletes glycogen stores &mdash; the worm starves over 2&ndash;3 days. Mebendazole&rsquo;s oral bioavailability is very low (&lt; 10%), which is therapeutically useful: high concentrations stay in the gut lumen where intestinal worms live, with minimal systemic exposure.<\/p>\n<h2 class=\"wp-block-heading\">Lupimeb indications and dose<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:14px;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Indicatie<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Dosering<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Schema<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Pinworm (Enterobius)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">100 mg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Single dose, repeat at 2 weeks<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Roundworm (Ascaris)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">100&nbsp;mg BID<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 3 days<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Hookworm (Ancylostoma, Necator)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">100&nbsp;mg BID<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 3 days<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">zweepworm (Trichuris)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">100&nbsp;mg BID<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 3 days; may extend to 5&ndash;7 days for heavy load<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Mixed nematode infection<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">100&nbsp;mg BID<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 3 days<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Tablets can be chewed, swallowed whole, or crushed and mixed with food.<\/p>\n<div style=\"background:#eef7ee;border-left:4px solid #4caf50;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>Pinworm protocol.<\/strong> Pinworm requires a second 100&nbsp;mg dose at 2 weeks because eggs already laid before the first dose hatch and complete a new cycle. Treat all household contacts on the same days. Wash bedding, towels, and underwear in hot water. Trim and scrub fingernails morning and night during the treatment window.<\/div>\n<h2 class=\"wp-block-heading\">Bijwerkingen<\/h2>\n<ul>\n<li><strong>Vaak voorkomend:<\/strong> mild abdominal pain, transient diarrhoea, flatulence as worms pass<\/li>\n<li><strong>Minder vaak:<\/strong> headache, dizziness, mild rash<\/li>\n<li><strong>Zeldzaam:<\/strong> reversible neutropenia (high-dose long courses), elevated transaminases, alopecia (very rare)<\/li>\n<li><strong>Zeer zeldzaam:<\/strong> Stevens-Johnson syndrome, toxic epidermal necrolysis<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Geneesmiddelinteracties<\/h2>\n<ul>\n<li><strong>Cimetidine<\/strong> &mdash; raises mebendazole plasma levels modestly; clinically relevant only in long courses for tissue parasites<\/li>\n<li><strong>Fenyto\u00efne, carbamazepine, rifampicine<\/strong> &mdash; reduce mebendazole levels (CYP induction)<\/li>\n<li><strong>Metronidazole<\/strong> &mdash; case reports of Stevens-Johnson syndrome with concurrent use; avoid if possible<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>Zwangerschap &amp; borstvoeding.<\/strong> Albendazol en mebendazol worden NIET aanbevolen in het eerste trimester (gegevens over teratogeniciteit bij dieren). Gebruik is acceptabel in het 2e\/3e trimester bij matige tot zware worminfecties. Gegevens over ivermectine tijdens zwangerschap zijn beperkt maar geruststellend in WHO-massabehandelingsprogramma's; vermijd in het eerste trimester waar alternatieven beschikbaar zijn. Praziquantel en pyrantel zijn compatibel met zwangerschap.<\/div>\n<div style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>Pediatrische opmerking.<\/strong> De meeste wormmiddelen zijn veilig vanaf 2 jaar en ouder; ivermectine is geregistreerd vanaf 15 kg lichaamsgewicht; albendazol 400 mg als eenmalige dosis is de WHO-standaard vanaf 1 jaar in massabehandelingsprogramma's. Onder de 2 jaar, kies voor pediatrische suspensies en raadpleeg een arts voor gewichtsgebonden dosering.<\/div>\n<h2 class=\"wp-block-heading\">Contra-indicaties<\/h2>\n<ul>\n<li>Hypersensitivity to mebendazole or other benzimidazoles<\/li>\n<li>Kinderen &lt; 1 jaar<\/li>\n<li>Eerste trimester van de zwangerschap<\/li>\n<li>Ernstige leverfunctiestoornis<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Opslag<\/h2>\n<p>Store Lupimeb below 30&deg;C in the original blister, away from light and moisture.<\/p>\n<h3 class=\"wp-block-heading\">Waarom bestellen bij MedsBase<\/h3>\n<p>Lupimeb is supplied from a <strong>WHO-GMP gecertificeerde fabrikant<\/strong>, discreet verpakt en wereldwijd verzonden. Elke bestelling valt onder onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance Policy<\/a> \u2014 u draagt nooit de kosten van een verloren pakket.<\/p>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3 class=\"wp-block-heading\">Can I just take one tablet?<\/h3>\n<p>For pinworm, yes &mdash; one 100&nbsp;mg dose, then a second at 2 weeks. For roundworm, hookworm, whipworm, or mixed infection, the standard course is 100&nbsp;mg twice daily for 3 days.<\/p>\n<h3 class=\"wp-block-heading\">Do I need to fast before Lupimeb?<\/h3>\n<p>No. Mebendazole works locally in the gut lumen and absorption is intentionally low. Take with or without food.<\/p>\n<h3 class=\"wp-block-heading\">Can my child chew Lupimeb?<\/h3>\n<p>Yes &mdash; the tablet is designed to be chewed, swallowed whole, or crushed into food. Chewing is fine for children old enough to spit out anything they dislike (typically age 4+).<\/p>\n<h3 class=\"wp-block-heading\">How is mebendazole different from albendazole?<\/h3>\n<p>Both are benzimidazoles with the same mechanism. Albendazole has higher systemic absorption (better for tissue-dwelling parasites like echinococcus), while mebendazole stays mostly in the gut lumen (preferred for some paediatric protocols and patients with hepatic impairment). For routine intestinal nematodes, both work.<\/p>\n<h3 class=\"wp-block-heading\">Will Lupimeb treat tapeworm?<\/h3>\n<p>Mebendazole has activity against some intestinal cestodes (Hymenolepis nana) but is NOT first-line for tapeworm. Use niclosamide or praziquantel for confirmed Taenia infection.<\/p>\n<h3 class=\"wp-block-heading\">How long until the worms are gone?<\/h3>\n<p>Adult worms are paralysed within 24&ndash;48&nbsp;hours and pass in faeces over the following 3&ndash;5 days. Visible worms in stool are normal and a sign the drug is working. Itching and other symptoms resolve within 1&ndash;2 weeks.<\/p>\n<h3 class=\"wp-block-heading\">Is Lupimeb safe in pregnancy?<\/h3>\n<p>Avoid in the first trimester. After week 13, mebendazole is acceptable for moderate-to-heavy worm burden &mdash; discuss with a clinician.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol with Lupimeb?<\/h3>\n<p>There is no specific alcohol interaction. Heavy alcohol use stresses the liver, and if the worm load is heavy enough to cause transient transaminase rise, abstaining for the treatment course is prudent.<\/p>\n<h3 class=\"wp-block-heading\">Does Lupimeb treat lice or scabies?<\/h3>\n<p>No. Mebendazole has no activity against ectoparasites &mdash; use ivermectin or permethrin for scabies and pediculicide shampoos or oral ivermectin for lice.<\/p>\n<h3 class=\"wp-block-heading\">Should I retest after treatment?<\/h3>\n<p>For routine pinworm or hookworm in an immunocompetent person with symptom resolution, no follow-up testing is needed. Persistent eosinophilia, weight loss, or recurring symptoms warrant repeat stool ova-and-parasite testing 2&ndash;4 weeks after treatment.<\/p>\n<p class=\"medsbase-link-boost-2026-05-07\" data-marker=\"mb-link-boost-wormentel\">Patients seeking extended parasite coverage beyond <a href=\"\/nl\/lupimeb\/\">Lupimeb<\/a> (mebendazole 100&nbsp;mg) may consider <a href=\"\/nl\/wormentel\/\">Wormentel (fenbendazol 222 \/ 500 mg)<\/a> as a fenbendazole alternative in the same benzimidazole class but with a broader organism spectrum covering Giardia, tapeworm, and Trichinella.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Andere antiparasitaire medicijnen<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/mebex\/\">Mebex (mebendazole 100 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/lupimeb\/\">Lupimeb (mebendazole 100 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/abd-400-albendazole\/\">ABD 400 (albendazole 400 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/nemocid\/\">Nemocid (pyrantelpamoaat)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/iverheal\/\">Iverheal (ivermectin)<\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:22px 0;border-radius:4px;font-size:14px;color:#444;\"><strong>Medisch disclaimer.<\/strong> Deze pagina is alleen voor educatieve doeleinden en vervangt geen professioneel medisch advies. Overleg met een gekwalificeerde arts voordat u een wormmiddel gebruikt, vooral als u zwanger bent of borstvoeding geeft, immuungecompromitteerd bent, een kind onder de 2 jaar behandelt of als de klachten aanhouden na een behandeling. Eosinofilie, gewichtsverlies, aanhoudende buikpijn of reisgerelateerde symptomen vereisen klinische evaluatie. Ernstige parasitaire infecties (neurocysticercose, strongyloides hyperinfectie, schistosomiasis met orgaanbetrokkenheid) worden door een specialist behandeld.<\/div>","protected":false},"excerpt":{"rendered":"<p>Lupimeb (mebendazole 100 mg chewable, Lupin) \u2014 benzimidazole anthelmintic for pinworm, roundworm, hookworm, and whipworm. Single-dose for pinworm; 3-day course for roundworm and whipworm.<\/p>","protected":false},"featured_media":58689,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3856],"product_tag":[4543,4544],"class_list":{"0":"post-58688","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-threadworm-treatment","9":"product_tag-lupimeb","10":"product_tag-mebendazole","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/58688","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=58688"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/58689"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=58688"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=58688"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=58688"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=58688"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}