{"id":58714,"date":"2024-02-28T05:24:45","date_gmt":"2024-02-28T05:24:45","guid":{"rendered":"https:\/\/medsname.com\/meftal\/"},"modified":"2026-05-01T10:49:14","modified_gmt":"2026-05-01T10:49:14","slug":"meftal","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/meftal\/","title":{"rendered":"Meftal"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Meftal?<\/h3>\n<p style=\"margin:0;\"><strong>Meftal<\/strong> is een merk van <strong>mefenamic acid<\/strong>, a prescription NSAID used for menstrual cramps, mild-to-moderate pain, fever, and inflammation. Available as <strong>250&nbsp;mg dispersible tablets and 500&nbsp;mg conventional tablets<\/strong>. Typical adult dose: 500&nbsp;mg initially, then 250&nbsp;mg every 6 hours as needed for up to 7 days. Take with food to minimise stomach irritation.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Wat u krijgt bij MedsBase:<\/strong> WHO-GMP gecertificeerde fabrikant \u00b7 Discrete verpakking \u00b7 Wereldwijde verzending \u00b7 1.400+ geverifieerde <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">klantbeoordelingen<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n<p><strong>Meftal<\/strong> is a widely trusted <strong>mefenamic acid<\/strong> tablet used to relieve <strong>menstrual cramps, mild-to-moderate pain, fever, and inflammation<\/strong>. Manufactured to pharmaceutical-grade standards, Meftal is available in <strong>250 mg dispersible tablets (DT)<\/strong> en <strong>500 mg conventional tablets<\/strong>, giving prescribers flexible dosing across adult and paediatric patients. Each tablet contains the same active ingredient as branded formulations such as Ponstan and Ponstel \u2014 at a fraction of the price.<\/p>\n<p>As a member of the <strong>fenamate class of non-steroidal anti-inflammatory drugs (NSAIDs)<\/strong>, mefenamic acid has been in clinical use for more than 50 years and is the first-line option recommended by many gynaecologists for primary dysmenorrhoea.<\/p>\n<h2 class=\"wp-block-heading\">What Is Meftal?<\/h2>\n<p>Meftal is the Indian brand name for <strong>mefenamic acid<\/strong> \u2014 a prescription-strength NSAID used as an analgesic, antipyretic, and anti-inflammatory. Unlike paracetamol, which acts almost entirely on the central nervous system, mefenamic acid works at the site of injury by blocking the enzymes that produce prostaglandins. This makes it particularly effective for pain driven by inflammation or smooth-muscle contractions.<\/p>\n<p>Meftal tablets are most frequently prescribed for:<\/p>\n<ul>\n<li><strong>Primary dysmenorrhoea<\/strong> (menstrual cramps)<\/li>\n<li><strong>Mild-to-moderate musculoskeletal pain<\/strong> \u2014 backache, strains, sprains<\/li>\n<li><strong>Post-dental and post-surgical pain<\/strong><\/li>\n<li><strong>Headache and migraine-associated pain<\/strong><\/li>\n<li><strong>Fever associated with inflammation<\/strong><\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">How Does Meftal Work?<\/h2>\n<p>Mefenamic acid is a <strong>non-selective cyclo-oxygenase (COX) inhibitor<\/strong>. Prostaglandins are lipid messengers produced via the COX-1 and COX-2 enzymes, and they are responsible for sensitising pain receptors, driving inflammation, raising body temperature during infection, and causing uterine contractions during menstruation. Here is how the process works:<\/p>\n<ul>\n<li>Tissue injury, infection, or hormonal signalling activates <strong>COX-1 and COX-2<\/strong><\/li>\n<li>COX enzymes convert arachidonic acid into <strong>prostaglandins (PGE\u2082, PGF\u2082\u03b1)<\/strong> and thromboxanes<\/li>\n<li>These prostaglandins sensitise nociceptors, dilate blood vessels, and cause smooth-muscle contraction<\/li>\n<li><strong>Meftal blocks COX<\/strong>, lowering prostaglandin production and directly reducing pain, swelling, fever, and menstrual cramping<\/li>\n<li>Mefenamic acid also has a <strong>small additional effect as a prostaglandin receptor antagonist<\/strong>, which contributes to its strong analgesic profile in dysmenorrhoea<\/li>\n<\/ul>\n<p>Het begin van de werking is doorgaans <strong>30\u201360 minuten<\/strong>, with peak plasma concentration reached in about 2\u20134 hours. The plasma half-life is short (~2 hours), which is why Meftal is usually dosed every 6\u20138 hours.<\/p>\n<h2 class=\"wp-block-heading\">Toepassingen en Indicaties<\/h2>\n<ul>\n<li><strong>Primary dysmenorrhoea<\/strong> \u2014 mefenamic acid is specifically licensed for menstrual pain and is recognised as a first-line option by the Royal College of Obstetricians and Gynaecologists<\/li>\n<li><strong>Menorrhagia (heavy menstrual bleeding)<\/strong> \u2014 can reduce blood loss by 20\u201350% when taken during menses<\/li>\n<li><strong>Acute pain<\/strong> \u2014 post-operative, post-dental, muscular, and traumatic pain<\/li>\n<li><strong>Osteoarthritis and rheumatoid arthritis<\/strong> \u2014 short-term symptomatic relief of joint stiffness and inflammation<\/li>\n<li><strong>Koorts<\/strong> \u2014 when paracetamol alone is insufficient, or when an anti-inflammatory effect is also desired<\/li>\n<li><strong>Headache and tension-type pain<\/strong><\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Meftal Dosage and Administration<\/h2>\n<table>\n<thead>\n<tr>\n<th>Indicatie<\/th>\n<th>Aanbevolen Dosering<\/th>\n<th>Frequency \/ Duration<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Dysmenorrhoea (menstrual cramps)<\/strong><\/td>\n<td>500 mg (initial) then 250 mg<\/td>\n<td>Every 6 hours, starting at onset of pain; max 3 days<\/td>\n<\/tr>\n<tr>\n<td><strong>Menorrhagia (heavy bleeding)<\/strong><\/td>\n<td>500 mg<\/td>\n<td>3 times daily, starting day 1 of menses, up to 5 days<\/td>\n<\/tr>\n<tr>\n<td><strong>Mild-to-moderate pain (adults)<\/strong><\/td>\n<td>500 mg (initial) then 250 mg<\/td>\n<td>Every 6 hours as needed; max 7 days<\/td>\n<\/tr>\n<tr>\n<td><strong>Koorts<\/strong><\/td>\n<td>500 mg (initial) then 250 mg<\/td>\n<td>Every 6 hours; max 7 days<\/td>\n<\/tr>\n<tr>\n<td><strong>Children 6 months \u2013 14 years<\/strong><\/td>\n<td>25 mg\/kg\/day in divided doses<\/td>\n<td>Under paediatric supervision only; max 7 days<\/td>\n<\/tr>\n<tr>\n<td><strong>Ouderen (65+)<\/strong><\/td>\n<td>250 mg<\/td>\n<td>Every 8 hours; lowest effective dose<\/td>\n<\/tr>\n<tr>\n<td><strong>Milde tot matige nierfunctiestoornis<\/strong><\/td>\n<td>250 mg<\/td>\n<td>Use with caution; monitor kidney function<\/td>\n<\/tr>\n<tr>\n<td><strong>Maximum daily adult dose<\/strong><\/td>\n<td>1,500 mg (three 500 mg tablets)<\/td>\n<td>Do not exceed<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3 class=\"wp-block-heading\">How to Take Meftal Properly<\/h3>\n<ul>\n<li>Swallow the tablet whole with a full glass of water<\/li>\n<li><strong>Always take Meftal with food or milk<\/strong> \u2014 this reduces the risk of stomach irritation, the most common side effect of NSAIDs<\/li>\n<li>For menstrual cramps, <strong>start at the first sign of pain<\/strong> or the day your period begins \u2014 earlier dosing gives better relief<\/li>\n<li>For dispersible tablets (250 mg DT), disperse in a spoonful of water before swallowing if preferred<\/li>\n<li>Do <strong>not take Meftal for longer than 7 consecutive days<\/strong> zonder medische evaluatie<\/li>\n<li>If a dose is missed and the next dose is within 2 hours, skip the missed dose \u2014 do not double up<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Side Effects of Meftal<\/h2>\n<p>Most people tolerate Meftal well when it is taken short-term at recommended doses. Side effects are dose-dependent and more likely with prolonged use.<\/p>\n<table>\n<thead>\n<tr>\n<th>Ernst<\/th>\n<th>Bijwerking<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Vaak (\u22651 op de 100)<\/strong><\/td>\n<td>Dyspepsia, nausea, abdominal pain, diarrhoea, heartburn, dizziness, drowsiness, headache<\/td>\n<\/tr>\n<tr>\n<td><strong>Uncommon (1 in 100 \u2013 1 in 1,000)<\/strong><\/td>\n<td>Skin rash, pruritus, oedema, tinnitus, elevated liver enzymes<\/td>\n<\/tr>\n<tr>\n<td><strong>Zeer zeldzaam (&lt;1 op de 1.000)<\/strong><\/td>\n<td>Gastrointestinal bleeding or ulceration, haemolytic anaemia, acute kidney injury, bronchospasm (especially in NSAID-sensitive asthmatics), photosensitivity<\/td>\n<\/tr>\n<tr>\n<td><strong>Zeer zeldzaam \/ ernstig<\/strong><\/td>\n<td>Stevens-Johnson syndrome, hepatitis, aseptic meningitis, agranulocytosis, anaphylaxis<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>Seek medical attention immediately<\/strong> if you notice black or tarry stools, vomiting blood, severe abdominal pain, yellowing of the eyes or skin, breathing difficulty, or a widespread skin rash.<\/p>\n<h2 class=\"wp-block-heading\">Waarschuwingen en voorzorgsmaatregelen<\/h2>\n<ul>\n<li><strong>Cardiovasculair risico<\/strong> \u2014 like all NSAIDs, mefenamic acid may increase the risk of heart attack or stroke with high-dose or long-term use<\/li>\n<li><strong>Gastrointestinal risk<\/strong> \u2014 may cause ulcers or bleeding, particularly in patients over 65 or those taking anticoagulants, corticosteroids, or other NSAIDs<\/li>\n<li><strong>Kidney function<\/strong> \u2014 avoid in dehydration, heart failure, or significant renal impairment; mefenamic acid is cleared by the kidneys<\/li>\n<li><strong>Astma<\/strong> \u2014 patients with a history of aspirin\/NSAID-induced bronchospasm should not take Meftal<\/li>\n<li><strong>Zwangerschap<\/strong> \u2014 avoid throughout pregnancy, particularly in the third trimester (risk of premature closure of the foetal ductus arteriosus)<\/li>\n<li><strong>Borstvoeding<\/strong> \u2014 small amounts pass into breast milk; short courses are generally acceptable, but discuss with a healthcare professional<\/li>\n<li><strong>Rijden<\/strong> \u2014 Meftal can cause drowsiness or dizziness; do not drive or operate machinery until you know how you react<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Contraindications \u2014 Who Should NOT Take Meftal<\/h2>\n<ul>\n<li>Active or recurrent peptic ulcer disease or gastrointestinal bleeding<\/li>\n<li>Severe heart failure, severe hypertension, or recent coronary artery bypass surgery<\/li>\n<li>Ernstige nier- of leverfunctiestoornis<\/li>\n<li>Known hypersensitivity to mefenamic acid, aspirin, or other NSAIDs<\/li>\n<li>Inflammatory bowel disease (Crohn&#8217;s disease, ulcerative colitis) \u2014 NSAIDs can trigger flares<\/li>\n<li>Third trimester of pregnancy<\/li>\n<li>Children under 6 months of age<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Geneesmiddelinteracties<\/h2>\n<table>\n<thead>\n<tr>\n<th>Geneesmiddel \/ Klasse<\/th>\n<th>Interactie<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Warfarin, apixaban, rivaroxaban<\/strong><\/td>\n<td>Increased bleeding risk \u2014 co-administration generally avoided<\/td>\n<\/tr>\n<tr>\n<td><strong>Lithium<\/strong><\/td>\n<td>Mefenamic acid reduces renal clearance \u2014 lithium toxicity risk<\/td>\n<\/tr>\n<tr>\n<td><strong>Methotrexaat<\/strong><\/td>\n<td>Increased methotrexate toxicity, especially at high MTX doses<\/td>\n<\/tr>\n<tr>\n<td><strong>ACE inhibitors, ARBs, diuretics<\/strong><\/td>\n<td>Reduced antihypertensive effect; increased risk of acute kidney injury<\/td>\n<\/tr>\n<tr>\n<td><strong>Other NSAIDs, aspirin, corticosteroids<\/strong><\/td>\n<td>Additive GI toxicity \u2014 avoid combination<\/td>\n<\/tr>\n<tr>\n<td><strong>SSRIs (sertraline, fluoxetine, etc.)<\/strong><\/td>\n<td>Increased GI bleeding risk<\/td>\n<\/tr>\n<tr>\n<td><strong>Ciclosporin, tacrolimus<\/strong><\/td>\n<td>Increased nephrotoxicity<\/td>\n<\/tr>\n<tr>\n<td><strong>Quinolone antibiotics<\/strong><\/td>\n<td>Possible increased seizure risk<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Always share a full list of your current medications, including over-the-counter products and herbal supplements, with your prescriber before starting Meftal.<\/p>\n<h2 class=\"wp-block-heading\">Wat te doen bij overdosering<\/h2>\n<p>Symptoms of mefenamic acid overdose include severe nausea and vomiting, abdominal pain, drowsiness, convulsions, and in severe cases coma and acute renal failure. There is no specific antidote \u2014 management is supportive, with activated charcoal if presentation is within 1 hour of ingestion. Seek emergency medical attention or contact your local poisons centre immediately.<\/p>\n<h2 class=\"wp-block-heading\">Bewaaradvies<\/h2>\n<ul>\n<li>Store below 25 \u00b0C in a dry place, away from direct sunlight<\/li>\n<li>Bewaar in de originele blisterverpakking tot gebruik<\/li>\n<li>Buiten bereik van kinderen en huisdieren houden<\/li>\n<li>Niet gebruiken na de vervaldatum die op de verpakking staat vermeld<\/li>\n<li>Dispose of unused tablets via a pharmacy take-back scheme where available \u2014 do not flush down the toilet<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Gerelateerde alternatieven op MedsBase<\/h2>\n<p>Looking for related pain or symptom relief options?<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/ondem-injection\/\" rel=\"noopener\">Ondem Injectie<\/a> \u2014 for nausea and vomiting that often accompany severe dysmenorrhoea<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/lox-2-jelly\/\" rel=\"noopener\">Lox 2% Jelly<\/a> \u2014 topical lidocaine for localised pain relief<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/placentrex-injection\/\" rel=\"noopener\">Placentrex-injectie<\/a> \u2014 for chronic inflammatory conditions<\/li>\n<\/ul>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3 class=\"wp-block-heading\">Is Meftal the same as Meftal Spas?<\/h3>\n<p>No. Meftal contains only mefenamic acid. <strong>Meftal Spas<\/strong> is a combination tablet containing mefenamic acid plus dicyclomine (an antispasmodic). Meftal Spas is often preferred when cramping is the dominant symptom; plain Meftal is sufficient when inflammation or fever is the main issue.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Meftal and paracetamol together?<\/h3>\n<p>Yes \u2014 mefenamic acid and paracetamol act on different pathways and are commonly combined for stronger pain relief. Do not, however, combine Meftal with another NSAID such as ibuprofen, diclofenac, or aspirin.<\/p>\n<h3 class=\"wp-block-heading\">How quickly does Meftal work for menstrual cramps?<\/h3>\n<p>Most women notice meaningful relief within 30\u201360 minutes of taking a 500 mg loading dose. Effectiveness is greatest when Meftal is started at the <strong>first sign of pain<\/strong> or the day the period begins.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Meftal while breastfeeding?<\/h3>\n<p>Short courses of mefenamic acid at recommended doses are generally considered compatible with breastfeeding, as only very small amounts enter breast milk. Always confirm with your doctor or pharmacist.<\/p>\n<h3 class=\"wp-block-heading\">Does Meftal cause drowsiness?<\/h3>\n<p>Mild drowsiness or dizziness can occur in some users, particularly at the start of treatment. Do not drive or operate machinery until you know how Meftal affects you.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Meftal on an empty stomach?<\/h3>\n<p>It is not recommended. Mefenamic acid can irritate the stomach lining; always take Meftal with food, milk, or a full glass of water.<\/p>\n<h3 class=\"wp-block-heading\">How long can I take Meftal?<\/h3>\n<p>Short-term use \u2014 generally no more than 7 consecutive days \u2014 is recommended. Longer courses should only be taken under medical supervision and with monitoring of kidney function and blood counts.<\/p>\n<h3 class=\"wp-block-heading\">Is Meftal safe during pregnancy?<\/h3>\n<p>Meftal should be avoided in pregnancy, particularly in the third trimester, because it can cause premature closure of the foetal ductus arteriosus and reduce amniotic fluid. If pain relief is needed during pregnancy, discuss paracetamol as a safer alternative with your doctor.<\/p>\n<h3 class=\"wp-block-heading\">Does Meftal interact with alcohol?<\/h3>\n<p>Alcohol increases the risk of stomach irritation and gastrointestinal bleeding when combined with any NSAID. Limit or avoid alcohol while taking Meftal.<\/p>\n<h3 class=\"wp-block-heading\">What is the difference between Meftal 250 mg DT and Meftal 500 mg?<\/h3>\n<p>The 250 mg DT (dispersible tablet) form is designed to dissolve in water, which is useful for children, elderly patients, or anyone with swallowing difficulties. The 500 mg conventional tablet is the standard adult strength. Total daily dose is what matters \u2014 not the individual tablet strength.<\/p>\n<p><!-- medsbase-faq-h3-converted --><\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Gerelateerde alternatieven<\/h3>\n<p>Andere producten in <strong>Chronische aandoeningen<\/strong> die klanten ook bekijken:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/budecort-inhaler\/\">Budecort Inhaler<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/carvego\/\">Carvego<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/maxiflo-rotacaps\/\">Maxiflo Rotacaps<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/riborea\/\">Riborea<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/lipaglyn\/\">Lipaglyn<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Relieves menstrual pain<br \/>\n\u2705 Reduces fever quickly<br \/>\n\u2705 Eases headache discomfort<br \/>\n\u2705 Alleviates muscle cramps<br \/>\n\u2705 Manages dental pain<\/p>\n<p>Meftal contains Mefenamic Acid.<\/p>","protected":false},"featured_media":58715,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3555],"product_tag":[4553,4554],"class_list":{"0":"post-58714","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-pain-relief-medication","9":"product_tag-mefenamic-acid","10":"product_tag-meftal","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/58714","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=58714"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/58715"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=58714"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=58714"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=58714"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=58714"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}