{"id":59138,"date":"2024-02-28T05:43:27","date_gmt":"2024-02-28T05:43:27","guid":{"rendered":"https:\/\/medsname.com\/risdone-mt\/"},"modified":"2026-04-30T10:24:03","modified_gmt":"2026-04-30T10:24:03","slug":"risdone-mt","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/risdone-mt\/","title":{"rendered":"Risdone MT"},"content":{"rendered":"

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\u26a1 Snel antwoord<\/h3>\n

Risdone MT (Risperidone 0.5 mg ODT) is an atypical antipsychotic for schizophrenia, bipolar mania, irritability in autism (paediatric and adolescent), and short-term aggression in dementia. Highest prolactin elevation of any atypical \u2014 relevant for fertility, menstrual function, and bone density.<\/p>\n<\/div>\n

\nWat u krijgt bij MedsBase:<\/strong> WHO-GMP gecertificeerde fabrikant \u00b7 Discrete verpakking \u00b7 Wereldwijde verzending \u00b7 1.400+ geverifieerde klantbeoordelingen<\/a>\n<\/div>\n

\ud83d\udce6 Elke bestelling is gedekt door onze Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n

Waarom bestellen bij MedsBase<\/h3>\n

Risdone MT at MedsBase is supplied directly from a WHO-GMP certified manufacturer in plain, discreet packaging. Every order is covered by our Reshipment Assurance Policy<\/a> \u2014 20 werkdagen levertermijn of wij sturen kosteloos opnieuw \u2014 en komt in aanmerking voor ons klantenloyaliteitsprogramma<\/a>. Wereldwijde verzending is beschikbaar naar de meeste bestemmingen.<\/p>\n

What Risdone MT is and how it works<\/h2>\n

Risdone MT is a risperidone orodispersible tablet supplied by Sun Pharma. Available strengths: 0.5 mg ODT<\/strong>. Risperidone is a strong D2 and 5-HT2A antagonist with \u03b11-adrenergic and H1 antihistamine activity, but minimal anticholinergic effect. The strong D2 blockade explains both the strong antipsychotic effect and the high rate of EPS and prolactin elevation.<\/p>\n

The MT (mouth-disintegrating \/ orodispersible) formulation dissolves on the tongue without water \u2014 useful in acutely psychotic patients with covert non-adherence and in dysphagia.<\/p>\n

Indicaties en dosering<\/h2>\n\n\n\n\n\n\n\n\n\n
Indicatie<\/th>\nStartdosering<\/th>\nStreefdosering<\/th>\nMaximaal<\/th>\n<\/tr>\n<\/thead>\n
Schizophrenia (adult)<\/td>\n1\u20132 mg OD or BID<\/td>\n4\u20136 mg\/day<\/td>\n16 mg<\/td>\n<\/tr>\n
Schizophrenia (adolescent \u2265 13 y)<\/td>\n0.5 mg OD<\/td>\n3 mg\/day<\/td>\n6 mg<\/td>\n<\/tr>\n
Bipolar mania<\/td>\n2\u20133 mg OD<\/td>\n2\u20136 mg\/day<\/td>\n6 mg<\/td>\n<\/tr>\n
Autism irritability (paediatric \u2265 5 y)<\/td>\n0.25\u20130.5 mg OD<\/td>\n0.5\u20133 mg\/day weight-based<\/td>\n2.5\u20133 mg<\/td>\n<\/tr>\n
Older adults \/ dementia (off-label, last-resort)<\/td>\n0.25 mg OD<\/td>\n0.5\u20131 mg\/day<\/td>\n2 mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Belangrijke veiligheidsoverwegingen<\/h2>\n
\nFDA black-box \u2014 dementia-related psychosis<\/strong><\/p>\n

All atypical antipsychotics carry an FDA black-box warning for increased mortality (mostly cardiovascular and infectious) when used to treat behavioural disturbance in older adults with dementia. Atypicals are not approved for dementia-related psychosis or agitation<\/strong>. Use in this population is off-label, last-resort, time-limited, and requires explicit risk-benefit conversation.<\/p>\n<\/div>\n

\nHighest prolactin elevation of any atypical<\/strong><\/p>\n

Risperidone produces marked, dose-dependent hyperprolactinaemia. Clinical consequences:<\/strong> amenorrhoea, galactorrhoea, anovulation, and reduced bone density in women; loss of libido, erectile dysfunction, and gynaecomastia in men; in long-term use, accelerated osteoporosis. Check prolactin if symptoms suggest hyperprolactinaemia. If hyperprolactinaemia is symptomatic, consider switching to aripiprazole (lowers prolactin) or quetiapine.<\/p>\n<\/div>\n

\nEPS \/ dose-dependent<\/strong><\/p>\n

Above approximately 6 mg\/day, risperidone increasingly behaves like a typical antipsychotic on EPS \u2014 rigidity, tremor, akathisia, dystonia. Tardive dyskinesia risk is real but lower than typicals. Stay below 6 mg\/day where possible.<\/p>\n<\/div>\n

\nOrthostatic hypotension<\/strong><\/p>\n

\u03b11 antagonism \u2014 common at initiation, particularly in older adults. Titrate slowly.<\/p>\n<\/div>\n

\nMetabolic burden<\/strong><\/p>\n

Less than olanzapine but real \u2014 weight gain typically 2\u20134 kg over 6 months. Monitor weight, fasting glucose, fasting lipids at baseline, 12 weeks, then 6-monthly.<\/p>\n<\/div>\n

Veelvoorkomende bijwerkingen<\/h2>\n