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Nilol<\/strong> is een fixed-dose combination of atenolol (beta-blocker) + nifedipine (dihydropyridine calcium-channel blocker)<\/strong> from a WHO-GMP certified manufacturer — widely prescribed in India and the subcontinent for combined hypertension and angina, particularly in patients where a single-drug regimen has failed. The two drugs work via complementary mechanisms: atenolol reduces cardiac output and heart rate (beta-1 blockade); nifedipine causes direct arterial vasodilation via L-type calcium channel blockade. The beta-blocker blunts the reflex tachycardia that bare nifedipine would otherwise produce. Typical dose: \u00e9\u00e9n tablet eenmaal per dag<\/strong>. Contraindications inherit from both components: asthma \/ severe COPD \/ second-third degree heart block \/ acute heart failure \/ severe aortic stenosis \/ recent MI \/ cardiogenic shock<\/strong>.<\/p>\n<\/div>\n \ud83d\udce6 Elke bestelling is gedekt door onze Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n Nilol is an oral tablet from a WHO-GMP certified manufacturer containing:<\/p>\n The combination originated in 1980s European cardiology (brand Tenif, Tenoretic) and remains popular in India for patients with both hypertension and stable angina. The two drugs target different mechanisms: atenolol for heart-rate and contractility reduction; nifedipine for direct arterial vasodilation. The beta-blocker prevents the reflex tachycardia that nifedipine monotherapy would otherwise cause.<\/p>\n Dosering:<\/strong> one tablet once daily, usually morning. Maximum 2 tablets\/day. Target BP <140\/90 (or <130\/80 with comorbidity).<\/p>\n Monitoring:<\/strong> baseline + periodic ECG (atenolol bradycardia \/ nifedipine effect on PR interval), pulse, BP, peripheral oedema (nifedipine commonly causes ankle swelling).<\/p>\n Atenolol-related:<\/strong> fatigue, cold extremities, bradycardia, exercise intolerance, mild fatigue, erectile dysfunction, masked hypoglycaemia in diabetics.<\/p>\n Nifedipine-related:<\/strong><\/p>\n Store below 25°C; protect from light.<\/p>\n Complementary mechanisms and side-effect-mitigation. Bare nifedipine causes reflex tachycardia (sympathetic response to vasodilation); atenolol blocks that reflex, giving smoother BP control. For patients with both hypertension AND stable angina, the two drugs target both diseases simultaneously.<\/p>\n Dose-related peripheral oedema occurs in up to 25% of long-term nifedipine users. It is NOT from fluid overload — it is from pre-capillary vasodilation increasing hydrostatic pressure in the lower legs. Treatment: dose reduction, leg elevation, compression stockings, or switch to a non-dihydropyridine CCB (verapamil, diltiazem) or a different vasodilator class (ACE inhibitor, ARB).<\/p>\n Atenolol is associated with intrauterine growth restriction in pregnancy (more so than other beta-blockers) and neonatal bradycardia\/hypoglycaemia. For antihypertensive use in pregnancy, labetalol<\/a>, methyldopa, and nifedipine-monotherapy (not this FDC) are the preferred options.<\/p>\n You can buy Nilol (atenolol + nifedipine 50 mg + 20 mg, 30-180 tablets) from MedsBase with discreet packaging and worldwide shipping.<\/p>\n <\/p>\n Andere producten in Chronische aandoeningen<\/strong> die klanten ook bekijken:<\/p>\n Nilol is a fixed-dose combination of atenolol 50 mg + nifedipine 20 mg \u2014 beta-blocker plus dihydropyridine calcium-channel blocker for combined hypertension and stable angina. Complementary mechanisms; atenolol blocks reflex tachycardia from nifedipine vasodilation. Once daily, morning. Not for pregnancy.<\/p>","protected":false},"featured_media":59418,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3260,3356],"product_tag":[3365,3390,4693],"class_list":{"0":"post-59417","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-heart-blood-pressure","9":"product_cat-high-blood-pressure-medication","10":"product_tag-atenolol","11":"product_tag-nifedipine","12":"product_tag-nilol","14":"first","15":"instock","16":"shipping-taxable","17":"purchasable","18":"product-type-variable","19":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/59417","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=59417"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/59418"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=59417"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=59417"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=59417"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=59417"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Waarom bestellen bij MedsBase<\/h3>\n
What Is Nilol?<\/h2>\n
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How Nilol Works<\/h2>\n
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Toepassingen & Dosering<\/h2>\n
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Bijwerkingen<\/h2>\n
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Contra-indicaties<\/h2>\n
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Opslag<\/h2>\n
Why combine atenolol with nifedipine?<\/h3>\n
What about the ankle swelling from nifedipine?<\/h3>\n
Why not use this in pregnancy?<\/h3>\n
Where can I buy Nilol online?<\/h3>\n
Gerelateerde b\u00e8tablokkers & antihypertensiva<\/h2>\n
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Gerelateerde alternatieven<\/h3>\n
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