{"id":59535,"date":"2024-02-28T06:02:28","date_gmt":"2024-02-28T06:02:28","guid":{"rendered":"https:\/\/medsname.com\/l-thyroid\/"},"modified":"2026-04-30T10:16:34","modified_gmt":"2026-04-30T10:16:34","slug":"l-thyroid","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/l-thyroid\/","title":{"rendered":"L-Thyroid"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is L-Thyroid?<\/h3>\n<p style=\"margin:0;\"><strong>L-Thyroid<\/strong> is <strong>levothyroxine natrium<\/strong> (synthetic thyroxine, T4) (available in the full 25 to 150 mcg titration range), the first-line treatment for <strong>hypothyroidism<\/strong> (underactive thyroid). Taken once daily on an empty stomach, 30&ndash;60 minutes before food, coffee or any other medication. Dose is titrated against TSH every 6&ndash;8 weeks until stable.<\/p>\n<p><!-- mb-thyropace-link --><\/p>\n<p><em>Looking for nutritional thyroid support rather than hormone replacement? See <a href=\"\/nl\/thyropace\/\">Thyropace tablet (L-Tyrosine + Iodine + Selenium)<\/a> \u2014 a daily nutritional capsule that is NOT a substitute for L-Thyroid in diagnosed hypothyroidism.<\/em><\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Wat u krijgt bij MedsBase:<\/strong> WHO-GMP gecertificeerde fabrikant \u00b7 Discrete verpakking \u00b7 Wereldwijde verzending \u00b7 1.400+ geverifieerde <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">klantbeoordelingen<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n<div style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:16px 20px;margin:0 0 24px 0;border-radius:4px;font-size:14px;\"><strong>&#128274; Why order L-Thyroid from MedsBase?<\/strong> Geverifieerde voorraad van WHO-GMP gecertificeerde fabrikant \u00b7 discrete verpakking \u00b7 wereldwijde verzending \u00b7 1.400+ klanten in 50+ landen \u00b7 beoordeeld met 4.9\u2605. <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">Lees klantbeoordelingen<\/a>.<\/div>\n<h2 class=\"wp-block-heading\"><strong>What Is L-Thyroid?<\/strong><\/h2>\n<p>L-Thyroid is a branded generic of <strong>levothyroxine natrium<\/strong>, a synthetic copy of the thyroid hormone <strong>thyroxine (T4)<\/strong>. After absorption, T4 is converted in peripheral tissues to the more active <strong>triiodothyronine (T3)<\/strong>. Levothyroxine is the standard therapy for <strong>primary hypothyroidism<\/strong>, the most common cause of which is autoimmune <strong>Hashimoto&rsquo;s thyroiditis<\/strong>. Available strengths: 25 mcg, 50 mcg, 75 mcg, 100 mcg, 125 mcg and 150 mcg. Manufactured by a WHO-GMP certified manufacturer.<\/p>\n<p>L-Thyroid is the budget-priced levothyroxine option in our range &mdash; identical active ingredient to Eltroxin and Thyronorm, lower brand premium. Useful for long-term replacement once a stable dose is established. Stay on a single brand once your TSH is in target.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Genitale herpes (eerste episode):<\/strong><\/h2>\n<ul>\n<li><strong>Primary hypothyroidism<\/strong> &mdash; autoimmune (Hashimoto&rsquo;s), post-surgical (after thyroidectomy), post-radioiodine ablation, congenital hypothyroidism.<\/li>\n<li><strong>Subclinical hypothyroidism<\/strong> &mdash; treatment is usually offered when TSH is persistently &gt;10 mIU\/L, or when antibodies are positive and the patient has clear hypothyroid symptoms.<\/li>\n<li><strong>TSH suppression after differentiated thyroid cancer<\/strong> &mdash; supraphysiological doses suppress TSH and reduce recurrence risk.<\/li>\n<li><strong>Endemic and sporadic non-toxic goitre<\/strong> &mdash; reduces gland volume by lowering TSH drive.<\/li>\n<li><strong>Myxoedeemcoma<\/strong> &mdash; emergency replacement, usually parenteral, in a hospital setting.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\"><strong>How to Take L-Thyroid &mdash; CRITICAL Timing Rules<\/strong><\/h2>\n<p>Levothyroxine absorption is highly sensitive to food, drinks and other medications. The following rules are essential, not optional:<\/p>\n<ul>\n<li>Neem <strong>first thing in the morning, on an empty stomach, with a full glass of plain water<\/strong>.<\/li>\n<li>Wacht <strong>at least 30&ndash;60 minutes<\/strong> before eating, drinking coffee or tea, or taking any other tablet.<\/li>\n<li>Scheid van <strong>calcium, iron, magnesium, zinc and aluminium-containing supplements or antacids<\/strong> by at least 4 hours &mdash; these dramatically reduce absorption.<\/li>\n<li>Scheid van <strong>protonpompremmers<\/strong> (omeprazole, esomeprazole, pantoprazole) &mdash; gastric acid is required for full absorption.<\/li>\n<li>Scheid van <strong>cholestyramine, colestipol, sevelamer and orlistat<\/strong> by 4 hours &mdash; these bind levothyroxine in the gut.<\/li>\n<li>Vermijden <strong>soy products, walnuts and high-fibre cereals<\/strong> at the same time as the dose.<\/li>\n<li>If you cannot tolerate morning dosing, an evening bedtime dose at least 3 hours after the last meal is an evidence-based alternative.<\/li>\n<li>If you miss a dose, take it as soon as you remember unless it is nearly time for the next day&rsquo;s dose. <strong>Never double-dose.<\/strong> Levothyroxine has a long half-life (~7 days) so an occasional missed dose is forgiving.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\"><strong>Starting Dose, Titration and TSH Targets<\/strong><\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:16px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;\">Pati\u00ebntengroep<\/th>\n<th style=\"padding:8px;text-align:left;\">Startdosis<\/th>\n<th style=\"padding:8px;text-align:left;\">Titratie<\/th>\n<th style=\"padding:8px;text-align:left;\">TSH target<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">Young, otherwise healthy adult<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">~1.6 mcg\/kg\/day (typically 100&ndash;125 mcg)<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">Recheck TSH at 6&ndash;8 weeks; adjust by 12.5&ndash;25 mcg.<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">0.5&ndash;2.5 mIU\/L<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">&gt;65 years or known cardiac disease<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">25&ndash;50 mcg\/day<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">Increase by 12.5&ndash;25 mcg every 4&ndash;6 weeks<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">Upper third of reference range (often 1&ndash;4 mIU\/L)<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">Pregnancy (pre-existing hypothyroidism)<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">Increase pre-pregnancy dose by 25&ndash;50% as soon as pregnancy confirmed<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">Recheck TSH every 4 weeks in first half, then every trimester<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">&lt;2.5 mIU\/L (T1), &lt;3.0 mIU\/L (T2\/T3)<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">Post-thyroidectomy for cancer (TSH suppression)<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">~2.0 mcg\/kg\/day<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">Recheck TSH at 6&ndash;8 weeks; aim for risk-tier-specific target<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">0.1&ndash;0.5 mIU\/L (intermediate-risk); &lt;0.1 (high-risk)<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;\">Kinderen<\/td>\n<td style=\"padding:8px;\">10&ndash;15 mcg\/kg\/day in newborns; tapers with age (specialist-led)<\/td>\n<td style=\"padding:8px;\">Frequent monitoring &mdash; growth and neurodevelopment depend on adequate replacement<\/td>\n<td style=\"padding:8px;\">Age-specific paediatric range<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Once TSH is in target and stable, annual TSH monitoring is sufficient. Recheck sooner if symptoms change, weight changes by &gt;5 kg, a new interacting drug is started, or pregnancy is planned.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Side Effects of L-Thyroid<\/strong><\/h2>\n<p>True drug-allergic reactions to levothyroxine are rare. Most reported &ldquo;side effects&rdquo; reflect <strong>over- or under-dosing<\/strong>:<\/p>\n<table style=\"width:100%;border-collapse:collapse;margin:16px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;\">Over-treatment (TSH too low)<\/th>\n<th style=\"padding:8px;text-align:left;\">Under-treatment (TSH still high)<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;vertical-align:top;\">Palpitations, anxiety, insomnia, tremor, heat intolerance, unintentional weight loss, diarrhoea, muscle weakness, irregular periods. Long-term: increased atrial fibrillation risk in older adults; accelerated bone loss especially in post-menopausal women.<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;vertical-align:top;\">Persistent fatigue, cold intolerance, weight gain, constipation, dry skin, hair shedding, bradycardia, depressed mood, brain fog, oedema. In pregnancy: miscarriage and impaired fetal neurodevelopment.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Rare hypersensitivity to tablet excipients (lactose, dyes) can occur &mdash; switching to a different brand of levothyroxine usually resolves it. Hair shedding can also occur in the first few weeks of replacement and resolves as TSH normalises.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Who Should Not Take L-Thyroid<\/strong><\/h2>\n<ul>\n<li><strong>Untreated adrenal insufficiency<\/strong> &mdash; levothyroxine accelerates cortisol clearance and can precipitate adrenal crisis. Treat the adrenal axis first.<\/li>\n<li><strong>Acute myocardial infarction<\/strong> or unstable angina (relative) &mdash; start at low doses with cardiology input.<\/li>\n<li><strong>Untreated thyrotoxicosis<\/strong> &mdash; the gland is already over-active.<\/li>\n<li><strong>Overgevoeligheid bekend<\/strong> to levothyroxine sodium or excipients.<\/li>\n<li>Use as a <strong>weight-loss agent in euthyroid people<\/strong> is dangerous and not an indication.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\"><strong>Geneesmiddelinteracties<\/strong><\/h2>\n<ul>\n<li><strong>Reduce absorption (separate by &ge;4 hours):<\/strong> calcium, iron, magnesium, aluminium and zinc supplements; cholestyramine, colestipol, sevelamer; sucralfate; orlistat.<\/li>\n<li><strong>Reduce absorption (avoid co-dosing):<\/strong> proton pump inhibitors, soy protein, high-fibre meals, espresso coffee.<\/li>\n<li><strong>Increase levothyroxine requirement (induce metabolism \/ displace from binding):<\/strong> phenytoin, carbamazepine, rifampicin, oral oestrogens (HRT, combined contraception), tamoxifen, raloxifene, sertraline, amiodarone (variable effect).<\/li>\n<li><strong>Levothyroxine alters effect of other drugs:<\/strong> potentiates warfarin (recheck INR after dose changes); may raise insulin \/ oral antidiabetic requirement; over-treatment increases digoxin requirement and risk of arrhythmia.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\"><strong>Opslag<\/strong><\/h2>\n<p>Store at room temperature (15&ndash;25&nbsp;&deg;C), away from moisture and direct heat. Keep tablets in the original blister or bottle &mdash; humidity reduces potency. Do not use after the printed expiry date.<\/p>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3 class=\"wp-block-heading\">Is L-Thyroid the same as Synthroid or Levoxyl?<\/h3>\n<p>Yes, the active ingredient is identical &mdash; <strong>levothyroxine natrium<\/strong>. The difference is the manufacturer, the inactive excipients, and the country of marketing. Bioequivalence between brands is generally close but not perfect, so it is sensible to stay on one brand once your TSH is stable. If you switch, recheck TSH 6&ndash;8 weeks later.<\/p>\n<h3 class=\"wp-block-heading\">Waarom moet ik het op een lege maag innemen?<\/h3>\n<p>Food, coffee and many supplements bind levothyroxine in the gut and cut absorption substantially. Taking it 30&ndash;60 minutes before food (or at bedtime &ge;3 hours after dinner) gives much more reliable blood levels &mdash; which is the difference between a stable TSH and one that bounces around.<\/p>\n<h3 class=\"wp-block-heading\">Hoelang duurt het voordat ik verbetering merk?<\/h3>\n<p>Some symptoms (energy, mood) start to improve within 1&ndash;2 weeks. Full effect on weight, hair, skin and cold tolerance can take 3&ndash;6 months. The objective measure &mdash; serum TSH &mdash; usually reaches the new steady state at about 6&ndash;8 weeks after a dose change.<\/p>\n<h3 class=\"wp-block-heading\">Will L-Thyroid help me lose weight?<\/h3>\n<p>Only if you are genuinely hypothyroid. In that case, replacing thyroid hormone restores normal metabolism and a few kilograms of water weight is often shed. Taking levothyroxine when your thyroid is normal does not cause meaningful fat loss and significantly raises the risk of atrial fibrillation, osteoporosis and muscle wasting.<\/p>\n<h3 class=\"wp-block-heading\">Can I take L-Thyroid during pregnancy?<\/h3>\n<p>Yes &mdash; levothyroxine is essential and safe in pregnancy. Untreated hypothyroidism increases the risk of miscarriage and impairs fetal neurodevelopment. The dose typically needs to rise by 25&ndash;50% as soon as pregnancy is confirmed; recheck TSH every 4 weeks in the first half of pregnancy.<\/p>\n<h3 class=\"wp-block-heading\">Why do calcium and iron matter so much?<\/h3>\n<p>Both bind levothyroxine in the gut and reduce absorption by up to half. Calcium-fortified orange juice, dairy, calcium-containing antacids and iron-rich multivitamins should be separated from your dose by at least 4 hours. The same applies to magnesium and zinc supplements.<\/p>\n<h3 class=\"wp-block-heading\">Is hypothyroidism for life?<\/h3>\n<p>For autoimmune (Hashimoto&rsquo;s), post-surgical and post-radioiodine hypothyroidism, almost always yes. Stopping replacement returns hypothyroid symptoms within a few weeks and TSH back into the high range within months. Subclinical hypothyroidism and post-viral thyroiditis can occasionally recover.<\/p>\n<h3 class=\"wp-block-heading\">Wat als ik een dosis vergeet?<\/h3>\n<p>Take it as soon as you remember unless it is close to your next day&rsquo;s dose. Never double up. Because levothyroxine has a long half-life (~7 days), the occasional missed dose has only a small effect on overall replacement.<\/p>\n<h3 class=\"wp-block-heading\">Why is my TSH still high (or now too low) after a dose change?<\/h3>\n<p>TSH responds slowly. Wait at least 6 weeks &mdash; ideally 8 &mdash; after any dose change before rechecking, otherwise the result reflects the old dose. Hidden causes of an unexpected TSH change include a new PPI, a new iron or calcium supplement, oestrogen therapy, pregnancy, dramatic weight change, or accidentally switching brands.<\/p>\n<h3 class=\"wp-block-heading\">Can L-Thyroid be combined with liothyronine (T3)?<\/h3>\n<p>Most patients do well on levothyroxine alone because T4 is converted to T3 in the body. A minority of patients with persistent symptoms despite a normal TSH may benefit from a small added dose of liothyronine, but the evidence is mixed and combination therapy is usually a specialist decision. <a href=\"https:\/\/medsbase.com\/nl\/liothyronine\/\">See our Liothyronine page<\/a> for the T4 vs T4+T3 evidence summary.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.9em;\">\n<p style=\"margin:0;\"><strong>\u2695\ufe0f Medische disclaimer:<\/strong> Deze informatie is educatief en vervangt geen medisch advies. Levothyroxine en liothyronine zijn dosisgevoelige hormonen \u2014 onderdosering veroorzaakt hypothyreo\u00efdie symptomen; overdosering veroorzaakt thyreotoxicose (hartkloppingen, atriumfibrilleren, versneld botverlies). Dosistitratie moet worden begeleid door seri\u00eble TSH (en vrij T4 \/ vrij T3 waar relevant) elke 6\u20138 weken. Bespreek eventuele wijzigingen met uw voorschrijver.<\/p>\n<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Gerelateerde alternatieven<\/h3>\n<p>Andere producten in <strong>Chronische aandoeningen<\/strong> die klanten ook bekijken:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/flomist-nasal-spray\/\">Flomist Nasal Spray<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/olmeheal\/\">Olmeheal<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/natrilix-sr\/\">Natrilix SR<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/melanocyl\/\">Melanocyl<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/diamox\/\">Diamox<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Regulates thyroid hormones<br \/>\n\u2705 Manages hypothyroidism symptoms<br \/>\n\u2705 Boosts energy levels<br \/>\n\u2705 Supports metabolism<br \/>\n\u2705 Improves overall well-being<\/p>\n<p>L-Thyroid contains Thyroxine Sodium.<\/p>","protected":false},"featured_media":59536,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3790],"product_tag":[4713,3792],"class_list":{"0":"post-59535","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-underactive-thyroid-treatment","9":"product_tag-l-thyroid","10":"product_tag-thyroxine","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/59535","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=59535"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/59536"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=59535"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=59535"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=59535"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=59535"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}