{"id":60050,"date":"2024-02-28T06:31:02","date_gmt":"2024-02-28T06:31:02","guid":{"rendered":"https:\/\/medsname.com\/permiforce-cream\/"},"modified":"2026-05-11T14:13:26","modified_gmt":"2026-05-11T14:13:26","slug":"permiforce-cream","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/permiforce-cream\/","title":{"rendered":"Permiforce Cream"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:6px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:1.15em;\">\u26a1 Quick Answer \u2014 What is Permiforce Cream?<\/h3>\n<p style=\"margin:0;\"><strong>Permiforce Cream<\/strong> is <strong>permethrin 5% topical cream<\/strong> in a 30 g tube \u2014 the WHO and CDC first-line treatment for scabies (<em>Sarcoptes scabiei<\/em>). Apply head-to-toe (neck-down in adults; whole body including face and scalp in infants) at bedtime, leave on 8\u201314 hours, wash off in the morning. Repeat application after 7 days. Treat all household members and close contacts simultaneously even if asymptomatic. Itch may persist 2\u20134 weeks after successful treatment (post-scabietic itch \u2014 not failure). Safe in pregnancy and in children from 2 months.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 18px;margin:18px 0;border-radius:6px;font-size:0.95em;\">\n<strong>\ud83c\udfed WHO-GMP gecertificeerde fabrikant<\/strong> \u00b7 <strong>\ud83d\udce6 Discrete verpakking<\/strong> (gewone envelop) \u00b7 <strong>\ud83c\udf0d Wereldwijde verzending<\/strong> met <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance<\/strong><\/a> \u00b7 <strong>\u2b50 1.400+ klanten<\/strong> \u2014 <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">lees beoordelingen<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n<h3 class=\"wp-block-heading\">Waarom bestellen bij MedsBase<\/h3>\n<p>Choosing Permiforce Cream from MedsBase gives you:<\/p>\n<ul>\n<li><strong>WHO-GMP gecertificeerd<\/strong> \u2014 afkomstig uit ge\u00efnspecteerde productiefaciliteiten<\/li>\n<li><strong>Discrete verpakking<\/strong> \u2014 eenvoudige envelop, zonder zichtbare medicatienaam of apotheekmerk<\/li>\n<li><strong>Wereldwijde verzending<\/strong> met <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance<\/a> \u2014 elke bestelling verzekerd<\/li>\n<li><strong>Geverifieerde klantbeoordelingen<\/strong> \u2014 <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">1.400+ beoordelingen<\/a> in het gehele assortiment<\/li>\n<li><strong>Meerdere betaalmogelijkheden<\/strong> \u2014 inclusief 10% korting bij betaling met cryptocurrency<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">What is Permiforce Cream?<\/h2>\n<p>Permiforce Cream is a <strong>permethrin 5% w\/w topical cream<\/strong> for the treatment of scabies and other ectoparasitic skin infestations, supplied in a <strong>30 g tube<\/strong> by a WHO-GMP-certified manufacturer. Permethrin is a synthetic pyrethroid scabicide and pediculicide that has been the global first-line scabies treatment for over three decades. It appears on the WHO Model List of Essential Medicines and is recommended as preferred therapy by the CDC, the European Academy of Dermatology and Venereology, and most national clinical guidelines.<\/p>\n<h2 class=\"wp-block-heading\">How does permethrin 5% work?<\/h2>\n<p>Permethrin binds to voltage-gated sodium channels in the parasite&#8217;s nerve cells, holding them open and preventing repolarisation. The mite is paralysed and dies. Mammalian sodium channels are conformationally different and recover from permethrin binding very quickly \u2014 this selectivity is why permethrin is highly toxic to arthropods but has an excellent safety profile in humans (systemic absorption from intact skin is &lt; 2 % of the applied dose).<\/p>\n<h2 class=\"wp-block-heading\">Indicaties<\/h2>\n<ul>\n<li><strong>Schurft<\/strong> (<em>Sarcoptes scabiei var. hominis<\/em>) \u2014 first-line topical treatment in adults, children, and infants over 2 months<\/li>\n<li><strong>Gekorrelde (Noorse) schurft<\/strong> \u2014 combined with oral ivermectin under medical supervision<\/li>\n<li><strong>Schaamluizen<\/strong> (<em>Pthirus pubis<\/em>) \u2014 applied to affected areas<\/li>\n<li><strong>Body lice<\/strong> (<em>Pediculus humanus corporis<\/em>) \u2014 usually adjunct to clothing\/bedding hygiene<\/li>\n<\/ul>\n<p>For head lice, the lower-strength <a href=\"https:\/\/medsbase.com\/nl\/perlice-cream\/\">Perlice Cream (permethrin 1% lotion)<\/a> is the appropriate formulation.<\/p>\n<h2 class=\"wp-block-heading\">How to apply Permiforce Cream \u2014 scabies protocol<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;\">Stap<\/th>\n<th style=\"padding:8px;text-align:left;\">Wat te doen<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #eee;\">1. Bad \/ douche<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #eee;\">Have a warm bath or shower; <strong>dry the skin thoroughly<\/strong>. Skin must be cool and dry \u2014 heat increases absorption.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #eee;background:#f9f9f9;\">2. Cover entire body<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #eee;background:#f9f9f9;\">Apply a thin layer to the <strong>whole body from the neck down<\/strong> (in infants and the very elderly, also include face, ears, and scalp \u2014 avoiding eyes and mouth). Pay particular attention to <strong>between fingers and toes, under fingernails \/ toenails (cut them short first), wrists, elbows, armpits, breasts, waistline, buttocks, genitals, and behind ears<\/strong>. Mites preferentially burrow in these warm, folded sites.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #eee;\">3. Leave on 8\u201314 hours<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #eee;\">Apply at bedtime; sleep with cream on. <strong>Do not wash hands<\/strong> or any treated area during the contact period \u2014 re-apply if you do.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #eee;background:#f9f9f9;\">4. Wash off<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #eee;background:#f9f9f9;\">In the morning, wash off thoroughly with soap and water.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;\">5. Repeat after 7 days<\/td>\n<td style=\"padding:8px;\">A second full-body application 7 days later is recommended to kill mites that hatched from eggs after the first treatment (permethrin is less ovicidal than against active mites).<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div style=\"background:#eef7ee;border-left:4px solid #4caf50;padding:14px 18px;margin:18px 0;border-radius:6px;\">\n<strong>Treat the whole household at once.<\/strong> Scabies has a 4\u20136 week asymptomatic incubation period, so close contacts may be carrying mites without itching yet. Treating only the symptomatic family member almost guarantees re-infection. Wash bedding, towels, and clothing worn in the previous 3 days at \u2265 60 \u00b0C, or seal them in a plastic bag for 72 hours (mites die without a human host within ~3 days).\n<\/div>\n<h2 class=\"wp-block-heading\">Quantity guide per application<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;\">Pati\u00ebnt<\/th>\n<th style=\"padding:8px;text-align:left;\">Approximate amount<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #eee;\">Adult, average build<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #eee;\">~30 g (one full tube)<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #eee;background:#f9f9f9;\">Older child<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #eee;background:#f9f9f9;\">~15\u201320 g<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #eee;\">Young child (1\u20135 years)<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #eee;\">~7\u201310 g<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;\">Infant (2\u201312 months)<\/td>\n<td style=\"padding:8px;\">~3\u20135 g \u2014 apply to whole body including face\/scalp under medical guidance<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>For a couple or a household of four, plan on <strong>2 tubes per application \u00d7 2 applications = 4 tubes total<\/strong>.<\/p>\n<h2 class=\"wp-block-heading\">Bijwerkingen<\/h2>\n<p>Permethrin 5% cream is well tolerated. Reactions are usually local and mild:<\/p>\n<ul>\n<li>Mild burning, stinging, or tingling on application (especially on excoriated skin)<\/li>\n<li>Transient itching that may worsen briefly during treatment (dying mites release allergens)<\/li>\n<li>Skin redness, dryness, or mild irritation<\/li>\n<li>Rare: contact allergy; severe burning; rash<\/li>\n<\/ul>\n<p><strong>Post-scabietic itch<\/strong> \u2014 itching can persist for 2\u20134 weeks after a successful course because the dead mites and faeces remain in the skin and the immune response continues. This is <strong>niet<\/strong> treatment failure. Use a fragrance-free emollient and a short course of a sedating antihistamine at bedtime if it disturbs sleep. Persistent burrows or new lesions after 2 weeks suggests true treatment failure or re-infection \u2014 re-treat and review contacts.<\/p>\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and children<\/h2>\n<ul>\n<li><strong>Zwangerschap:<\/strong> permethrin is regarded as the safest scabicide in pregnancy at any trimester (systemic absorption &lt; 2 %); first-line per BNF, CDC, and Australian Therapeutic Guidelines.<\/li>\n<li><strong>Borstvoeding:<\/strong> compatible. Wash off before breastfeeding and avoid applying to nipple area.<\/li>\n<li><strong>Children \u2265 2 months:<\/strong> safe; in infants and young children apply to the whole body including the face and scalp (avoiding eyes and mouth).<\/li>\n<li><strong>Infants &lt; 2 months:<\/strong> use under specialist guidance only.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Geneesmiddelinteracties<\/h2>\n<p>None clinically significant. Topical permethrin has minimal systemic absorption, so no meaningful interaction with oral medications. Avoid using other topical scabicides simultaneously to prevent additive irritation.<\/p>\n<h2 class=\"wp-block-heading\">Contra-indicaties<\/h2>\n<ul>\n<li>Hypersensitivity to permethrin, other pyrethroids, or any pyrethrin (note: chrysanthemum allergy can cross-react)<\/li>\n<li>Active inflammatory dermatosis (severe eczema or psoriasis flare) \u2014 wait until skin barrier improves or use under specialist guidance<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Opslag<\/h2>\n<p>Store below 25 \u00b0C; do not freeze. Keep tube tightly closed; out of reach of children. Once opened, use within the manufacturer&#8217;s stated period (usually 6 months).<\/p>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3 class=\"wp-block-heading\">How fast does permethrin 5% work for scabies?<\/h3>\n<p>The mites are killed within hours of the first application \u2014 but the itch can persist for 2\u20134 weeks afterwards because of immune response to retained mite antigens. Cure (no new burrows, no new lesions) is judged at 2\u20134 weeks, not at day 1.<\/p>\n<h3 class=\"wp-block-heading\">Why a second application after 7 days?<\/h3>\n<p>Permethrin kills active mites efficiently but is less ovicidal. Eggs that survive the first application hatch over the next 1\u20133 days; the second treatment kills the newly hatched mites before they can lay another generation.<\/p>\n<h3 class=\"wp-block-heading\">Do I really need to treat everyone in my household?<\/h3>\n<p>Yes. Scabies has a 4\u20136 week incubation period, so close contacts (anyone sleeping in the same household, sexual partners, regular skin-to-skin caregivers) may be infested without itching yet. Treating only the symptomatic person almost guarantees re-infection within weeks.<\/p>\n<h3 class=\"wp-block-heading\">Permethrin 5% vs oral ivermectin \u2014 which is better?<\/h3>\n<p>For typical scabies, permethrin 5% is first-line because of its long safety record and low cost. Oral ivermectin (e.g. <a href=\"https:\/\/medsbase.com\/nl\/iverjohn\/\">Iverjohn<\/a> of <a href=\"https:\/\/medsbase.com\/nl\/verpin\/\">Verpin<\/a>) is preferred when topical compliance is impossible (institutional outbreaks, mass treatment, mobility-limited patients) and is essential for crusted (Norwegian) scabies in combination with permethrin. The two are often used together for severe or refractory cases.<\/p>\n<h3 class=\"wp-block-heading\">Can I use Permiforce Cream on my face?<\/h3>\n<p>In adults, avoid the face routinely. In infants, very young children, and the immunocompromised, the face and scalp must be included because mite burrows can occur there \u2014 apply a thin layer carefully, avoiding eyes, nostrils, and mouth.<\/p>\n<h3 class=\"wp-block-heading\">Why do I still itch a week after treatment?<\/h3>\n<p>Post-scabietic itch is the immune response to dead mites, mite faeces, and burrow proteins still present in the skin. It is normal for 2\u20134 weeks. Use a fragrance-free emollient, a mild topical steroid (1 % hydrocortisone) for inflamed patches, and an antihistamine at night. New burrows or new active lesions after 2 weeks suggests true failure or re-infection \u2014 repeat treatment and re-check contacts.<\/p>\n<h3 class=\"wp-block-heading\">What if I sweat or wash a treated area during the 8 hours?<\/h3>\n<p>Re-apply Permiforce Cream to that area immediately. Permethrin needs prolonged contact to be reliably effective.<\/p>\n<h3 class=\"wp-block-heading\">Is Permiforce Cream safe in pregnancy?<\/h3>\n<p>Yes \u2014 permethrin 5 % is the preferred scabicide in pregnancy at any trimester. Systemic absorption from intact skin is &lt; 2 % and there is no signal of teratogenicity in the available literature.<\/p>\n<h3 class=\"wp-block-heading\">Can I treat a baby with scabies using Permiforce?<\/h3>\n<p>Yes from age 2 months. In infants apply to the whole body including face and scalp (avoiding eyes and mouth), trim fingernails, and consider mittens to prevent the cream being licked off.<\/p>\n<h3 class=\"wp-block-heading\">How is scabies different from eczema?<\/h3>\n<p>Scabies typically gives <strong>severe night-time itching<\/strong>, characteristic burrow lines (small grey-pink threads ~5 mm long, often between fingers, on wrists, around the waist, breasts, or genitals), and itching in close contacts. Eczema is more often patchy, recurrent, with a personal or family history of atopy and no contagion to others. When in doubt, a clinical exam \u00b1 dermoscopy or skin scrape confirms.<\/p>\n<h2 class=\"wp-block-heading\">Andere behandelingen voor luizen &amp; schurft<\/h2>\n<p class=\"medsbase-link-boost-2026-05-11\" data-marker=\"mb-link-boost-ivrea-shampoo\">In households treating concurrent scabies with <a href=\"https:\/\/medsbase.com\/nl\/permiforce-cream\/\">Permiforce Cr\u00e8me (permetrine 5%)<\/a> who also need head-lice management, clinicians sometimes consolidate to a single ivermectin-class regimen; <a href=\"https:\/\/medsbase.com\/nl\/ivrea-shampoo\/\">Ivrea Shampoo (ivermectine 1% shampoo)<\/a> provides a scalp-applied option within the same antiparasitic drug family.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/perlice-cream\/\"><strong>Perlice Cream<\/strong><\/a> \u2014 permethrin 1 % lotion for head lice<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/iverjohn\/\"><strong>Iverjohn<\/strong><\/a> \u2014 oral ivermectin 3 \/ 6 \/ 12 mg for scabies, lice and broad antiparasitic use<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/verpin\/\"><strong>Verpin<\/strong><\/a> \u2014 ivermectine 6 mg tabletten, alternatief oraal schema<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/ivrea-cream\/\"><strong>Ivrea Cream<\/strong><\/a> \u2014 topical 1 % ivermectin for rosacea \/ Demodex \/ off-label small-area scabies<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/scabiheal-lotion\/\"><strong>Scabiheal Lotion<\/strong><\/a> \u2014 second-line lindane scabicide where permethrin and ivermectin have failed<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Medische Disclaimer<\/h2>\n<p>Deze pagina is voor educatieve doeleinden en is geen vervanging voor medisch advies. Resistente of atypische besmettingen, aanhoudende jeuk ondanks correcte toepassing, besmette kinderen &lt; 2 jaar, immuungecompromitteerde pati\u00ebnten (risico op crusted\/Noorse schurft) en gevallen van zwangerschap\/borstvoeding vereisen klinische beoordeling. Ernstige wijdverspreide huidinfectie, koorts of systemische symptomen na een behandelingskuur vereisen dringend medisch onderzoek. Overleg altijd met een arts over behandeling tijdens zwangerschap of borstvoeding.<\/p>","protected":false},"excerpt":{"rendered":"<p>\u2705 Eliminates scabies mites<br \/>\n\u2705 Verlicht jeuk<br \/>\n\u2705 Treats lice infestation<br \/>\n\u2705 Soothes irritated skin<br \/>\n\u2705 Quick relief<\/p>\n<p>Permiforce Cream contains Permethrin.<\/p>","protected":false},"featured_media":60051,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3579],"product_tag":[4579,4790],"class_list":{"0":"post-60050","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-lice-scabies-treatment","9":"product_tag-permethrin","10":"product_tag-permiforce-cream","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/60050","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=60050"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/60051"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=60050"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=60050"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=60050"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=60050"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}