{"id":60650,"date":"2024-02-28T07:00:29","date_gmt":"2024-02-28T07:00:29","guid":{"rendered":"https:\/\/medsname.com\/setrol-injection\/"},"modified":"2026-04-30T10:23:43","modified_gmt":"2026-04-30T10:23:43","slug":"setrol-injection","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/setrol-injection\/","title":{"rendered":"Setrol-injectie"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:0 0 18px 0;border-radius:4px;\">\n<h3 style=\"margin:0 0 8px 0;font-size:1.05em;\">Snelle antwoord<\/h3>\n<p><strong>Setrol-injectie<\/strong> bevat <strong>sodium tetradecyl sulfate (STS) 3% or 1%<\/strong> \u2014 a detergent sclerosing agent used by trained clinicians for sclerotherapy of varicose veins and telangiectasias (spider veins). It is delivered as a foamed or liquid intravenous injection into the affected vein under ultrasound or visual guidance. <strong>This is NOT a self-administered medication.<\/strong><\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f6f8;border:1px solid #e1e4e8;border-radius:4px;padding:14px 18px;margin:18px 0;display:flex;flex-wrap:wrap;gap:14px;font-size:0.95em;\"><span>\u2705 <strong>WHO-GMP gecertificeerd<\/strong> fabrikant<\/span><span>\ud83d\udce6 <strong>Discrete verpakking<\/strong><\/span><span>\ud83c\udf0d <strong>Wereldwijde verzending<\/strong><\/span><span>\ud83d\udcac <a href=\"\/nl\/reviews\/\">1.400+ klantbeoordelingen<\/a><\/span><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<h2>What sodium tetradecyl sulfate is<\/h2>\n<p>Sodium tetradecyl sulfate (STS, also known as STD or sotradecol) is a long-chain fatty-alcohol sulphate detergent. When injected into a vein, it disrupts the endothelial cell membrane, causing an inflammatory cascade that leads to thrombosis, fibrosis and eventually fibrotic obliteration of the vein lumen. The vein is then absorbed and disappears over weeks to months. STS is one of two FDA-approved sclerosants in the United States (the other is polidocanol).<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<h3 style=\"margin:0 0 8px 0;font-size:1.05em;\">Sclerotherapy is a procedure \u2014 not a self-injection medication<\/h3>\n<p>Setrol Injection must be administered by a vascular surgeon, dermatologist, interventional radiologist or other physician trained in sclerotherapy. Inadvertent intra-arterial injection causes ischaemic limb necrosis. Extravasation causes skin sloughing. Foam STS injection above the level of the heart is associated with rare visual disturbance and migraine-like aura. Self-administration is not safe.<\/p>\n<\/div>\n<h2>Indicaties<\/h2>\n<ul>\n<li><strong>Varicose veins<\/strong> of the great and small saphenous veins, accessory saphenous and tributary veins.<\/li>\n<li><strong>Telangiectasias and reticular veins<\/strong> (spider veins) of the lower limb.<\/li>\n<li><strong>Venous malformations<\/strong> \u2014 selected vascular anomalies.<\/li>\n<li><strong>Haemorrhoidal sclerotherapy<\/strong> (lower concentrations).<\/li>\n<li><strong>Endoscopic treatment of bleeding oesophageal varices<\/strong> (specialist hospital use; largely replaced by band ligation and tissue glue for variceal bleeding).<\/li>\n<\/ul>\n<h2>Concentrations and use<\/h2>\n<table>\n<thead>\n<tr>\n<th>Vessel<\/th>\n<th>Concentration<\/th>\n<th>Volume per session<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Telangiectasias (spider veins)<\/td>\n<td>0.1\u20130.25%<\/td>\n<td>0.1\u20130.5 ml per site<\/td>\n<\/tr>\n<tr>\n<td>Reticular veins (1\u20133 mm)<\/td>\n<td>0.25\u20130.5%<\/td>\n<td>0.5\u20131 ml per site<\/td>\n<\/tr>\n<tr>\n<td>Varicose tributaries (3\u20136 mm)<\/td>\n<td>0.5\u20131%<\/td>\n<td>2\u20134 ml as foam<\/td>\n<\/tr>\n<tr>\n<td>Saphenous trunks (\u2265 6 mm)<\/td>\n<td>1\u20133% (foam)<\/td>\n<td>4\u201310 ml as foam under ultrasound<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Foam sclerotherapy (Tessari technique: 1 part liquid to 4 parts air via two-syringe-and-3-way-tap method) gives ~3-4\u00d7 the surface area of liquid STS and is preferred for medium and large veins.<\/p>\n<h2>Procedure essentials (clinician summary)<\/h2>\n<ul>\n<li>Doppler \/ duplex ultrasound mapping of the venous tree before treatment.<\/li>\n<li>Patient supine; treated leg elevated for trunk treatment, level for spider veins.<\/li>\n<li>Compression stockings (class II, 23\u201332 mmHg) immediately after for 1\u20136 weeks depending on vessel calibre.<\/li>\n<li>Walk for 30 minutes after treatment; avoid prolonged standing or air travel for 1\u20132 weeks.<\/li>\n<li>Follow-up duplex at 4\u20136 weeks for trunk treatment to assess closure.<\/li>\n<\/ul>\n<h2>Adverse effects<\/h2>\n<ul>\n<li><strong>Vaak voorkomend:<\/strong> hyperpigmentation along the treated vein (5\u201330%, usually resolves over months); transient bruising; pain at injection site; superficial thrombophlebitis; matting (new fine telangiectasias adjacent to treated area).<\/li>\n<li><strong>Minder vaak voorkomend:<\/strong> deep vein thrombosis (&lt; 1%), especially with high-volume foam.<\/li>\n<li><strong>Zeldzaam maar ernstig:<\/strong> visual disturbance \/ migraine aura with foam (presumed paradoxical embolism through patent foramen ovale), allergic reaction including anaphylaxis, skin necrosis from extravasation, intra-arterial injection causing limb ischaemia.<\/li>\n<\/ul>\n<h2>Contra-indicaties<\/h2>\n<ul>\n<li>Known hypersensitivity to sodium tetradecyl sulfate<\/li>\n<li>Acute superficial or deep venous thrombosis<\/li>\n<li>Significant peripheral arterial disease (ABI &lt; 0.6)<\/li>\n<li>Pregnancy and breastfeeding (relative \u2014 defer treatment)<\/li>\n<li>Known right-to-left cardiac shunt (relative; consider for foam)<\/li>\n<li>Inability to ambulate after the procedure<\/li>\n<li>Severe systemic disease, immobility, hypercoagulable states<\/li>\n<\/ul>\n<h2>Opslag<\/h2>\n<p>Store below 25 \u00b0C, away from light. Do not freeze. Discard any opened ampoule within 24 hours.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Setrol Injection is supplied through a WHO-GMP certified manufacturer with full COA documentation. We ship worldwide in plain, discreet packaging, and every order is covered by our <a href=\"\/nl\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance Policy<\/a>. Uw betalingsbeschrijving bij betaling per kaart toont de gereguleerde betalingsverwerker (een gereguleerde kaartbetalingverwerker), nooit \"MedsBase\" of een medicijnnaam.<\/p>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3>Can I inject Setrol myself at home?<\/h3>\n<p>No. Sodium tetradecyl sulfate is administered intravenously by a trained clinician with ultrasound guidance for trunk veins and good visualisation for spider veins. Self-administration risks intra-arterial injection (causing limb necrosis), extravasation (causing skin sloughing) and DVT.<\/p>\n<h3>How is sclerotherapy different from laser treatment?<\/h3>\n<p>Sclerotherapy injects a chemical irritant directly into the vein. Laser ablation (endovenous laser, EVLT, or radiofrequency RFA) thermally seals the saphenous trunk through a fibre passed inside it. Both produce vein closure; choice depends on vein size, anatomy and operator preference. Spider veins are usually treated by sclerotherapy; saphenous trunks \u2265 6 mm are commonly treated by EVLT\/RFA with adjunctive sclerotherapy of tributaries.<\/p>\n<h3>How many sessions will I need?<\/h3>\n<p>Spider veins typically need 2\u20134 sessions spaced 4\u20138 weeks apart. Reticular veins 1\u20133 sessions. Saphenous trunk treatment: 1 session for the trunk plus 1\u20133 follow-up sessions for residual tributaries.<\/p>\n<h3>Will the veins come back?<\/h3>\n<p>Treated veins do not return. New veins can form (recurrence rate 20\u201330% over 5 years for varicose disease) because the underlying valvular incompetence in adjacent vessels can progress. Compression stockings, weight management and avoiding prolonged standing slow recurrence.<\/p>\n<h3>Is sclerotherapy painful?<\/h3>\n<p>Most patients describe brief stinging or burning at injection that lasts a few seconds. Foam injection into trunk veins is usually painless beyond the needle stick. Post-procedure mild ache and tightness for 1\u20133 days is normal.<\/p>\n<h3>Wat als ik zwanger ben?<\/h3>\n<p>Defer elective sclerotherapy until after pregnancy and breastfeeding. Many leg veins improve spontaneously postpartum and are best assessed 6 months after delivery.<\/p>\n<h3>Can it be used for haemorrhoids?<\/h3>\n<p>Yes \u2014 STS is used for sclerotherapy of grade I\u2013II internal haemorrhoids at lower concentrations. This is a hospital or clinic procedure performed by a colorectal surgeon or proctologist.<\/p>\n<h3>Why do I need compression stockings afterwards?<\/h3>\n<p>Compression promotes vein closure, reduces post-treatment pain and bruising, and lowers the risk of DVT, hyperpigmentation and matting. Class II 23\u201332 mmHg is standard for 1\u20136 weeks depending on vessel size.<\/p>\n<h3>What is &#8220;matting&#8221; and how is it prevented?<\/h3>\n<p>Matting is the appearance of new fine red telangiectasias near the treated area, often around 4\u20136 weeks post-treatment. Risk factors are oestrogen exposure, larger feeding veins left untreated, and high concentrations. Most matting fades over 6\u201312 months. Prevention: treat feeding veins first, use the lowest effective concentration.<\/p>\n<h3>Can I drink alcohol or take aspirin around the procedure?<\/h3>\n<p>Alcohol on the day of treatment increases bruising slightly. Aspirin and NSAIDs are usually continued \u2014 they do not significantly affect outcomes and in some practices are encouraged in the first week to reduce inflammatory pigmentation.<\/p>\n<h2>Other Vascular &#038; Circulation Medications<\/h2>\n<ul>\n<li><a href=\"\/nl\/heart-blood-pressure\/\">All Heart &amp; Blood Pressure Medications<\/a><\/li>\n<li><a href=\"\/nl\/atorvatin\/\">Atorvatin (atorvastatin) \u2014 lipid management, vascular health<\/a><\/li>\n<li><a href=\"\/nl\/trental-400\/\">Trental 400 (pentoxifylline) \u2014 peripheral vascular flow<\/a><\/li>\n<li><a href=\"\/nl\/eliquis\/\">Eliquis (apixaban) \u2014 DOAC for venous thromboembolism<\/a><\/li>\n<li><a href=\"\/nl\/calaptin-sr\/\">Calaptin SR (verapamil) \u2014 vascular smooth muscle \/ hypertension<\/a><\/li>\n<\/ul>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:24px 0 0 0;border-radius:4px;\">\n<h3 style=\"margin:0 0 8px 0;font-size:1.05em;\">Medische Disclaimer<\/h3>\n<p style=\"margin:0;\">Deze informatie is uitsluitend bedoeld voor educatieve doeleinden en is geen vervanging voor medisch advies. Raadpleeg altijd een gekwalificeerde zorgverlener voordat u met een medicatie begint, deze wijzigt of stopt.<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u2705 Treats varicose veins effectively<br \/>\n\u2705 Reduces vein inflammation<br \/>\n\u2705 Verbeterde bloeddoorstroming<br \/>\n\u2705 Minimizes pain and discomfort<br \/>\n\u2705 Injectable for convenience<\/p>\n<p>Setrol Injection contains Sodium Tetradecyl Sulfate.<\/p>","protected":false},"featured_media":60651,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3260],"product_tag":[4896,4897],"class_list":{"0":"post-60650","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-heart-blood-pressure","9":"product_tag-setrol-injection","10":"product_tag-sodium-tetradecyl-sulfate","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/60650","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=60650"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/60651"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=60650"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=60650"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=60650"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=60650"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}