{"id":60815,"date":"2024-02-28T07:10:05","date_gmt":"2024-02-28T07:10:05","guid":{"rendered":"https:\/\/medsname.com\/thiamine-hcl-100\/"},"modified":"2026-04-30T10:23:42","modified_gmt":"2026-04-30T10:23:42","slug":"thiamine-hcl-100","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/thiamine-hcl-100\/","title":{"rendered":"Thiamine HCL 100"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<h3 style=\"margin-top:0;\">Snelle antwoord<\/h3>\n<p><strong>Thiamine HCL 100 (thiamine (vitamin B1) 100 mg tablet)<\/strong> is high-dose oral thiamine for treatment of thiamine deficiency, alcohol-related neuropathy, beriberi, and as Wernicke prophylaxis at risk patients.<\/p>\n<ul style=\"margin-bottom:0;\">\n<li>Thiamine 100 mg per tablet &mdash; full replacement strength<\/li>\n<li>Indications: alcohol use disorder, refeeding syndrome prophylaxis, beriberi, hyperemesis<\/li>\n<li>Long-term oral 100&ndash;200 mg\/day for chronic deficiency or alcohol use disorder<\/li>\n<li>WHO-GMP gecertificeerde fabrikant<\/li>\n<\/ul>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f6f8;border:1px solid #e0e4e7;padding:12px 16px;margin:18px 0;border-radius:4px;font-size:14px;color:#444;\">\n<strong>WHO-GMP gecertificeerde fabrikant<\/strong> \u00b7 Discrete verpakking \u00b7 Wereldwijde verzending \u00b7 <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\" style=\"color:#2c7cb0;\">1.400+ geverifieerde klantbeoordelingen<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<p style=\"font-size:13px;color:#666;margin:4px 0 18px;\">Elke bestelling wordt gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\" style=\"color:#2c7cb0;\">Reshipment Assurance Policy<\/a>.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Thiamine HCL 100 is sourced from a WHO-GMP certified manufacturer. Every order ships in discreet, unbranded packaging worldwide and is covered by our Reshipment Assurance Policy. Pay securely with credit card, SEPA bank transfer, or cryptocurrency. See our <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">1.400+ geverifieerde klantbeoordelingen<\/a>.<\/p>\n<h2>What is Thiamine HCL 100?<\/h2>\n<p>Thiamine HCL 100 is high-dose oral thiamine (vitamin B1) for replacement and maintenance therapy in deficiency. Thiamine is a coenzyme essential for carbohydrate metabolism (pyruvate dehydrogenase, transketolase, alpha-ketoglutarate dehydrogenase). Deficiency causes wet beriberi (high-output cardiac failure), dry beriberi (peripheral neuropathy), and Wernicke-Korsakoff syndrome.<\/p>\n<h2>Indicaties<\/h2>\n<ul>\n<li><strong>Alcoholstoornis<\/strong> &mdash; multi-decade chronic alcohol intake regularly causes deficiency. Long-term oral 100 mg twice daily is standard.<\/li>\n<li><strong>Wernicke-Korsakoff syndrome<\/strong> &mdash; classical triad of confusion, ataxia, ophthalmoplegia in alcohol-dependent or hyperemetic patients. Acute treatment is parenteral high-dose thiamine; oral 100 mg twice daily is for prevention and post-acute maintenance.<\/li>\n<li><strong>Beriberi<\/strong> &mdash; rare in food-secure populations; still seen in alcohol-dependent and severely malnourished patients<\/li>\n<li><strong>Refeeding syndrome prophylaxis<\/strong> &mdash; prior to refeeding any malnourished patient (anorexia, severe undernutrition, prolonged fasting), give parenteral thiamine first then oral maintenance<\/li>\n<li><strong>Hyperemesis gravidarum<\/strong> &mdash; pregnancy-related severe vomiting depletes thiamine; replacement protects against Wernicke&#8217;s<\/li>\n<li><strong>Chronic loop diuretic use<\/strong> with heart failure (loop diuretics deplete thiamine; supplementation has modest evidence in advanced heart failure)<\/li>\n<li><strong>Post-bariatrisch onderhoud<\/strong><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>Suspected Wernicke&#8217;s encephalopathy needs PARENTERAL high-dose thiamine first<\/strong><\/p>\n<p style=\"margin-bottom:0;\">Oral thiamine 100 mg\/tablet is appropriate for prevention and chronic maintenance. In suspected acute Wernicke&#8217;s encephalopathy (confusion, ataxia, ophthalmoplegia &mdash; especially in alcohol-dependent patients, hyperemesis, post-bariatric, or refeeding) the standard is IV thiamine 500 mg three times daily for 2&ndash;3 days then 250 mg\/day &mdash; oral is too slow and absorption is unreliable in this group. Never give glucose or carbohydrate to a thiamine-deficient patient before thiamine is replaced &mdash; this can precipitate Wernicke&#8217;s.<\/p>\n<\/div>\n<h3>Dosering<\/h3>\n<ul>\n<li><strong>Maintenance in alcohol use disorder<\/strong>: 100 mg orally twice daily long-term<\/li>\n<li><strong>Beriberi<\/strong>: 100&ndash;300 mg\/day in divided doses for several weeks, then maintenance<\/li>\n<li><strong>Refeeding prophylaxis<\/strong>: parenteral first; oral 100 mg twice daily during refeeding period<\/li>\n<li><strong>Hyperemesis gravidarum<\/strong>: parenteral thiamine 100 mg, then oral if tolerated<\/li>\n<li><strong>Heart failure on loop diuretic<\/strong>: 100 mg\/day oral<\/li>\n<\/ul>\n<h2>Bijwerkingen<\/h2>\n<ul>\n<li><strong>Generally very well tolerated<\/strong> &mdash; oral thiamine has an exceptional safety profile<\/li>\n<li><strong>Anaphylaxis<\/strong> &mdash; rare and almost exclusively reported with parenteral thiamine, not oral<\/li>\n<li><strong>Milde maag-darmklachten<\/strong> bij hoge doseringen<\/li>\n<\/ul>\n<h2>Geneesmiddelinteracties<\/h2>\n<p>Thiamine has no significant clinically relevant drug interactions. Loop diuretics deplete thiamine but supplementation does not interfere with diuretic action.<\/p>\n<h2>Contra-indicaties<\/h2>\n<ul>\n<li>Hypersensitivity to thiamine (rare)<\/li>\n<\/ul>\n<h2>Opslag<\/h2>\n<p>Bewaren onder 25\u00b0C in originele verpakking, beschermen tegen vocht.<\/p>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3>Why is thiamine so important in alcohol use?<\/h3>\n<p>Alcohol impairs thiamine absorption, increases urinary loss, and competes with thiamine-dependent enzymes. Long-term alcohol use causes Wernicke&#8217;s encephalopathy (acute, reversible if treated early) and Korsakoff psychosis (chronic, partially reversible). Both are essentially preventable with adequate thiamine.<\/p>\n<h3>Should I take thiamine if I drink heavily?<\/h3>\n<p>If you cannot or will not stop drinking, oral thiamine 100 mg twice daily reduces the risk of Wernicke&#8217;s &mdash; this is genuinely worth doing, even alongside ongoing drinking. Stopping alcohol is the actual treatment, but thiamine offers concrete protection while you work toward that.<\/p>\n<h3>What is refeeding syndrome?<\/h3>\n<p>Severe malnourishment depletes phosphate, magnesium, potassium, and thiamine. When carbohydrate refeeding starts, insulin surges and these intracellular shifts intensify, causing fatal arrhythmias, heart failure, and Wernicke&#8217;s. Refeeding always includes thiamine first, slow caloric increase, and electrolyte correction.<\/p>\n<h3>Can I take it without a deficiency?<\/h3>\n<p>Yes &mdash; thiamine has a wide safety margin and excess is excreted. Routine megadose without indication is pointless but harmless.<\/p>\n<h3>Hoe snel werkt het?<\/h3>\n<p>Acute Wernicke&#8217;s (with parenteral thiamine): ophthalmoplegia improves within hours, ataxia over days, confusion over days-to-weeks. Chronic alcoholic neuropathy: slow improvement over months, often incomplete. Beriberi cardiac symptoms: hours-to-days.<\/p>\n<h3>Is het veilig tijdens de zwangerschap?<\/h3>\n<p>Yes &mdash; safe and important in hyperemesis gravidarum to prevent Wernicke&#8217;s. The B6 + B12 + thiamine combination in nausea-of-pregnancy management is well established.<\/p>\n<h3>Should I take it with B-complex?<\/h3>\n<p>B-complex preparations contain thiamine but at lower doses. For prevention and maintenance, B-complex is sufficient. For active deficiency or alcohol use disorder, dedicated 100 mg thiamine is preferred &mdash; the dose in standard B-complex (often 5&ndash;20 mg) is below the therapeutic threshold for these indications.<\/p>\n<h3>Why does my doctor give parenteral thiamine in the ED?<\/h3>\n<p>Acute Wernicke&#8217;s suspicion needs parenteral high-dose thiamine because (a) oral absorption is impaired in alcohol-dependent patients, (b) gut absorption is slow when minutes matter, and (c) carbohydrate-containing IV fluids are likely to be given anyway and these can precipitate Wernicke&#8217;s in deficient patients without prior thiamine cover.<\/p>\n<h3>Will it help my fatigue?<\/h3>\n<p>Only if fatigue is from documented thiamine deficiency. Most fatigue is not from thiamine; check thyroid, ferritin, vitamin D, B12, depression, sleep apnoea first.<\/p>\n<h3>Hoe lang moet ik het gebruiken?<\/h3>\n<p>In alcohol use disorder, lifelong supplementation is reasonable while drinking continues and for at least a year after sobriety. Otherwise, until the underlying cause (malnutrition, refeeding, hyperemesis) resolves.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2>Andere Vitamines &amp; Mineralen<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/vitamin-b12-1500-mcg-tablets-nerve-health-energy\/\">Vitamine B12 1500 mcg<\/a> \u2014 hoge dosis oraal cyanocobalamine<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/walcobal-injection\/\">Walcobal Injectie<\/a> \u2014 methylcobalamine IM<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/polybion-ampoule\/\">Polybion Ampul<\/a> \u2014 B-complex parenteraal<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/beplex-forte\/\">Beplex Forte<\/a> \u2014 B-complex oraal<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/becozinc\/\">Becozinc<\/a> \u2014 B-complex met zink<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/thiamine-hcl-100\/\">Thiamine HCL 100<\/a> \u2014 thiamine 100 mg voor alcoholgerelateerde neuropathie<\/li>\n<\/ul>\n<h2>Medische Disclaimer<\/h2>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;color:#444;\">\nDeze pagina is alleen voor educatieve doeleinden en is geen vervanging voor professioneel medisch advies. Vitaminen- en mineralensuppletie zou idealiter moeten worden begeleid door laboratoriumonderzoek bij vermoeden van een tekort. Megadosesuppletie is niet onschadelijk \u2014 vitamine A is teratogeen, vitamine E verhoogt het bloedingrisico, b\u00e8tacaroteen verhoogt het risico op longkanker bij rokers en hooggedoseerd calcium heeft een cardiovasculair signaal. Zwangere of zogende pati\u00ebnten moeten de verloskundige richtlijnen voor prenatale suppletie volgen. Pati\u00ebnten die warfarine gebruiken, moeten hun vitamine K-inname stabiel houden. Pati\u00ebnten die levothyroxine, fluoroquinolonen of tetracyclines gebruiken, moeten ijzer en calcium met 4 uur scheiden. Geef altijd alle supplementen door aan uw voorschrijver en apotheker.\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u2705 Verhoogt het energieniveau<br \/>\n\u2705 Supports nerve function<br \/>\n\u2705 Verbetert de stofwisseling<br \/>\n\u2705 Verbeterd de cognitieve functie<br \/>\n\u2705 Promotes heart health<\/p>\n<p>Thiamine HCL 100 contains Thiamine.<\/p>","protected":false},"featured_media":60816,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3863],"product_tag":[4929,4930],"class_list":{"0":"post-60815","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-vitamins-and-minerals","9":"product_tag-thiamine","10":"product_tag-vitamin-b1","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/60815","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=60815"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/60816"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=60815"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=60815"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=60815"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=60815"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}