{"id":60946,"date":"2024-02-28T07:17:05","date_gmt":"2024-02-28T07:17:05","guid":{"rendered":"https:\/\/medsname.com\/kenacort\/"},"modified":"2026-04-30T10:23:40","modified_gmt":"2026-04-30T10:23:40","slug":"kenacort","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/kenacort\/","title":{"rendered":"Kenacort"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Kenacort?<\/h3>\n<p style=\"margin:0;\"><strong>Kenacort<\/strong> is an oral tablet from Abbott Healthcare containing <strong>triamcinolone acetonide 4 mg tablets<\/strong> &mdash; a medium-potency synthetic <strong>glucocorticoid<\/strong> with strong anti-inflammatory and immunosuppressive activity and <strong>almost no mineralocorticoid (fluid-retaining) effect<\/strong>. Used for systemic anti-inflammatory therapy across rheumatoid arthritis, lupus, asthma, IBD, vasculitis, allergic reactions and other inflammatory and autoimmune conditions. Standard adult anti-inflammatory dose: <strong>4&ndash;48 mg\/day<\/strong> in 1&ndash;4 divided doses, titrated to response. Triamcinolone 4 mg is approximately equivalent to prednisolone 5 mg (potency ratio ~5). <strong>Never stop abruptly after more than 2&ndash;3 weeks of daily use<\/strong> &mdash; the drug suppresses the body&#39;s own cortisol production (HPA-axis suppression) and abrupt withdrawal can precipitate adrenal crisis. Always taper under medical supervision. Common side effects: weight gain, raised blood sugar, raised blood pressure, mood change, bone loss, increased infection risk, cataract.<\/p>\n<\/div>\n<p><!-- medsbase-specialist-strip --><\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:0 0 24px 0;border-radius:4px;font-size:14px;\"><strong>\u2695 Geneesmiddel onder specialistisch toezicht \u2014 klinische begeleiding vereist.<\/strong> Dit is een ernstig immunomodulerend geneesmiddel met specifieke screeningsvereisten voorafgaand aan de behandeling, black-box waarschuwingen en verplichte laboratoriumcontroles. Het moet worden voorgeschreven en begeleid door een reumatoloog, gastro-enteroloog, dermatoloog of andere specialist met ervaring in het gebruik ervan. <strong>niet<\/strong> Zelf voorschrijven, zelf de dosering aanpassen of starten\/stoppen zonder instructie van de voorschrijver is niet toegestaan. Geef altijd uw huidige recept aan uw behandelend arts voordat u bestelt bij MedsBase.<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f6f8;border:1px solid #e1e4e8;border-radius:4px;padding:14px 18px;margin:18px 0;display:flex;flex-wrap:wrap;gap:14px;font-size:0.95em;\"><span>\u2705 <strong>WHO-GMP gecertificeerd<\/strong> fabrikant<\/span><span>\ud83d\udce6 <strong>Discrete verpakking<\/strong><\/span><span>\ud83c\udf0d <strong>Wereldwijde verzending<\/strong><\/span><span>\ud83d\udcac <a href=\"\/nl\/reviews\/\">1.400+ klantbeoordelingen<\/a><\/span><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n<h2 class=\"wp-block-heading\">What Is Kenacort?<\/h2>\n<p>Kenacort is an oral tablet manufactured by Abbott Healthcare containing <strong>triamcinolone acetonide<\/strong> &mdash; a synthetic corticosteroid in the glucocorticoid class. Glucocorticoids are the most powerful broad-spectrum anti-inflammatory and immunosuppressive drugs available, with effects across almost every tissue and organ system.<\/p>\n<p>Kenacort is the original Indian-market triamcinolone tablet from Abbott Healthcare. The 4 mg tablet is the only oral strength stocked &mdash; doses are built up by combining tablets (e.g. four 4 mg tablets = 16 mg daily). Available in 15, 30, 60, 90 and 180 tablet packs to support both short anti-inflammatory courses and longer-term low-dose maintenance.<\/p>\n<p>Triamcinolone 4 mg is approximately equivalent to prednisolone 5 mg (potency ratio ~5). The physiological daily cortisol output of a healthy adult is approximately 5&ndash;7.5 mg of prednisolone-equivalent &mdash; any dose above that is &ldquo;supraphysiological&rdquo; and begins to suppress the hypothalamic-pituitary-adrenal (HPA) axis.<\/p>\n<p><strong>Why triamcinolone instead of prednisolone?<\/strong> Triamcinolone has <strong>almost no mineralocorticoid (fluid-retaining, sodium-retaining) effect<\/strong> compared with prednisolone or hydrocortisone. This makes it a sensible oral choice in patients with poorly-controlled hypertension, congestive heart failure, severe oedema, or known intolerance of fluid retention on prednisolone. The trade-off is a slightly higher rate of muscle weakness (steroid myopathy) at high doses, particularly in older patients.<\/p>\n<h2 class=\"wp-block-heading\">How Does Kenacort Work?<\/h2>\n<p>Triamcinolone enters cells, binds the <strong>intracellular glucocorticoid receptor<\/strong>, and the receptor-drug complex translocates to the nucleus where it alters transcription of hundreds of genes. The end result is a broad dampening of the inflammatory cascade:<\/p>\n<ul>\n<li><strong>Suppresses pro-inflammatory cytokines<\/strong> (IL-1, IL-6, TNF-&alpha;, IFN-&gamma;) and chemokines.<\/li>\n<li><strong>Stabilises lysosomal membranes<\/strong>, reducing release of proteolytic enzymes into tissue.<\/li>\n<li><strong>Inhibits phospholipase A<sub>2<\/sub><\/strong> via lipocortin, cutting off the prostaglandin and leukotriene pathways upstream.<\/li>\n<li><strong>Reduces capillary permeability<\/strong> and tissue oedema.<\/li>\n<li><strong>Suppresses B- and T-lymphocyte function<\/strong> and circulating lymphocyte counts (relative lymphopenia).<\/li>\n<li><strong>Reduces eosinophil and basophil activity<\/strong>, partially explaining the rapid effect in asthma, allergy and eosinophilic conditions.<\/li>\n<\/ul>\n<p>Clinical onset (oral): symptomatic relief within <strong>hours to 1&ndash;2 days<\/strong> for most inflammatory conditions. Peak anti-inflammatory effect within 4&ndash;72 hours.<\/p>\n<h2 class=\"wp-block-heading\">Toepassingen en Indicaties<\/h2>\n<p>Kenacort is used across a wide range of inflammatory and autoimmune conditions. Because of its very low mineralocorticoid activity, it is particularly useful when fluid retention or sodium retention is a concern.<\/p>\n<ul>\n<li><strong>Reumato\u00efde artritis<\/strong> &mdash; bridge therapy during DMARD initiation, or low-dose maintenance adjunct<\/li>\n<li><strong>Systemische lupus erythematosus (SLE)<\/strong> &mdash; flare management<\/li>\n<li><strong>Asthma exacerbations and severe asthma maintenance<\/strong><\/li>\n<li><strong>Severe allergic reactions, urticaria, angioedema, atopic dermatitis flare<\/strong><\/li>\n<li><strong>Opvlammingen van inflammatoire darmziekten<\/strong> (Crohn&#39;s, ulcerative colitis)<\/li>\n<li><strong>Polymyalgia rheumatica<\/strong> &mdash; medium-dose induction with slow taper<\/li>\n<li><strong>Pemphigus vulgaris and other bullous skin diseases<\/strong><\/li>\n<li><strong>Vasculitis, sarcoidosis, autoimmune hepatitis<\/strong><\/li>\n<li><strong>Adrenocortical insufficiency<\/strong> &mdash; rarely first choice (hydrocortisone is preferred for replacement)<\/li>\n<\/ul>\n<p>Kenacort is <strong>niet<\/strong> appropriate for: undiagnosed joint pain, isolated mild eczema (topicals first), or any condition where shorter-acting prednisolone is preferred for tighter dose-titration.<\/p>\n<h2 class=\"wp-block-heading\">Kenacort Dosage and How to Take<\/h2>\n<p>Kenacort is supplied at <strong>4 mg tablets<\/strong>. Adult anti-inflammatory dosing typically ranges from 4 to 48 mg per day in 1&ndash;4 divided doses, titrated to clinical response.<\/p>\n<h3 class=\"wp-block-heading\">Typical starting doses by indication<\/h3>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Aandoening<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Triamcinolone dose<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Opmerkingen<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Asthma \/ COPD exacerbation<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">32&ndash;48 mg\/day<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">5&ndash;7 days, no taper needed<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Polymyalgia rheumatica<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">12&ndash;16 mg\/day<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Slow taper over 18&ndash;24 months<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Rheumatoid arthritis (low-dose)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">4&ndash;6 mg\/day<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Bridge during DMARD initiation<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">SLE flare<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">16&ndash;48 mg\/day<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Taper to lowest effective dose<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">IBD flare<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">32&ndash;48 mg\/day<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Taper over 8&ndash;12 weeks<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Ernstige allergische reactie<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">32&ndash;40 mg\/day<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">3\u20135 dagen<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3 class=\"wp-block-heading\">How to Take Kenacort Properly<\/h3>\n<ol>\n<li><strong>Neem de volledige dagelijkse dosis 's ochtends in tijdens het ontbijt<\/strong> (usually 7&ndash;9 a.m.). Morning dosing mimics the body&#39;s natural cortisol peak, minimises HPA-axis suppression, and reduces insomnia.<\/li>\n<li><strong>Neem altijd in met voedsel<\/strong> &mdash; substantially reduces gastric irritation.<\/li>\n<li><strong>Slik de tabletten in hun geheel door met water.<\/strong> Tablets may be split if scored.<\/li>\n<li><strong>Never stop abruptly after more than 2&ndash;3 weeks<\/strong> of daily use. Taper under medical supervision.<\/li>\n<li><strong>Draag een stero\u00efdenkaart<\/strong> if taking Kenacort for more than 3 weeks &mdash; alerts emergency clinicians to your HPA-suppression risk.<\/li>\n<li><strong>Botbescherming vanaf het begin<\/strong> &mdash; calcium 1,000&ndash;1,200 mg\/day + vitamin D 800&ndash;1,000 IU\/day. For courses &gt; 3 months at 6 mg\/day or higher, consider a bisphosphonate from day one in post-menopausal women and older men.<\/li>\n<li><strong>Controleer bloedsuiker, bloeddruk, gewicht.<\/strong> Steroids raise all three; pre-existing diabetes usually needs temporary insulin or oral-hypoglycaemic adjustment.<\/li>\n<li><strong>Vermijd levende vaccins<\/strong> at &ge; 16 mg\/day of triamcinolone (= 20 mg prednisolone equivalent) for 2+ weeks, and for 3 months after stopping.<\/li>\n<li><strong>Tell every healthcare provider you take Kenacort<\/strong> \u2014 vooral v\u00f3\u00f3r operaties of anesthesie.<\/li>\n<\/ol>\n<h2 class=\"wp-block-heading\">Stopping Kenacort &mdash; Why Tapering Matters<\/h2>\n<p>Exogenous corticosteroids suppress the hypothalamic-pituitary-adrenal (HPA) axis &mdash; the brain stops signalling the adrenal glands to make cortisol because the incoming drug is doing the job. When treatment lasts long enough for suppression to set in, the adrenal glands atrophy and need weeks to months to recover. If the drug is stopped abruptly, the patient has no cortisol &mdash; a life-threatening adrenal crisis can follow.<\/p>\n<ul>\n<li><strong>Courses shorter than 2&ndash;3 weeks<\/strong> at any dose &mdash; can usually be stopped without a taper.<\/li>\n<li><strong>Any course longer than 3 weeks<\/strong>, or any course above 32 mg\/day for more than 1 week &mdash; requires a supervised taper.<\/li>\n<li><strong>Standaard afbouwschema<\/strong>: reduce by 10&ndash;20% of current dose every 1&ndash;2 weeks until reaching physiological replacement (~5 mg prednisolone equivalent), then 1 mg every 2&ndash;4 weeks.<\/li>\n<li><strong>Als ontwenningsverschijnselen optreden<\/strong> (vermoeidheid, misselijkheid, gewrichtspijn, duizeligheid, terugkeer van de ziekte), ga een niveau terug en verminder langzamer.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Side Effects of Kenacort<\/h2>\n<p>Side effects of oral triamcinolone closely mirror those of other systemic glucocorticoids and are dose- and duration-dependent.<\/p>\n<p><strong>Kortdurend (dagen tot weken):<\/strong><\/p>\n<ul>\n<li>Toegenomen eetlust, gewichtstoename<\/li>\n<li>Mood elevation, occasionally agitation, insomnia, psychosis (higher doses)<\/li>\n<li>Verhoogde bloedsuikerspiegel (kan diabetes aan het licht brengen)<\/li>\n<li>Maagzuur en dyspepsie<\/li>\n<li>Acne-opflakkering<\/li>\n<li>Menstruatieonregelmatigheid<\/li>\n<\/ul>\n<p><strong>Middellang (weken tot maanden):<\/strong><\/p>\n<ul>\n<li>Cushingo\u00efd uiterlijk \u2014 vollemaansgezicht, centrale obesitas, bisonnek<\/li>\n<li>Thinning of skin, easy bruising, striae<\/li>\n<li><strong>Steroid myopathy &mdash; proximal leg weakness<\/strong> (more common with triamcinolone than with prednisolone)<\/li>\n<li>Verhoogde vatbaarheid voor bacteri\u00eble, virale en schimmelinfecties<\/li>\n<li>Cataract (especially posterior subcapsular) and raised intraocular pressure<\/li>\n<li>Avascular necrosis of the femoral head<\/li>\n<\/ul>\n<p><strong>Langdurig (maanden tot jaren):<\/strong><\/p>\n<ul>\n<li>Osteoporosis and fragility fractures<\/li>\n<li>Persisterende diabetes mellitus<\/li>\n<li>Adrenal atrophy and HPA suppression<\/li>\n<li>Groei-onderdrukking bij kinderen<\/li>\n<li>Ernstige immunosuppressie met opportunistische infecties (Pneumocystis, TB-reactivering)<\/li>\n<\/ul>\n<p><strong>Zeldzaam maar ernstig \u2014 zoek dringend medisch advies:<\/strong><\/p>\n<ul>\n<li>GI-bloeding of perforatie (vooral bij gelijktijdig gebruik van NSAID's)<\/li>\n<li>Severe psychiatric reaction, psychosis, mania<\/li>\n<li>Ernstige infectie, TB-reactivering, gedissemineerde VZV<\/li>\n<li>Adrenal crisis during\/after withdrawal<\/li>\n<li>Plotselinge veranderingen in het gezichtsvermogen \u2014 mogelijk stero\u00efdglaucoma<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Waarschuwingen en voorzorgsmaatregelen<\/h2>\n<ul>\n<li><strong>Actieve of onbehandelde infectie<\/strong> &mdash; steroids mask signs of infection and worsen outcomes. Do not use for undiagnosed fever. Established infection sometimes still requires steroid (e.g. severe COVID-19) but specialist judgement only.<\/li>\n<li><strong>Latente TB<\/strong> &mdash; screen before any prolonged or repeated course; consider isoniazid cover if positive.<\/li>\n<li><strong>Diabetes<\/strong> &mdash; expect significant worsening; up-titrate oral hypoglycaemics or insulin during the course.<\/li>\n<li><strong>Hypertension, heart failure<\/strong> &mdash; triamcinolone has minimal mineralocorticoid effect, so fluid retention is less than with prednisolone, but BP can still rise via direct vascular effects.<\/li>\n<li><strong>Peptic ulcer disease, history of GI bleed, NSAID co-prescription<\/strong> &mdash; co-prescribe a PPI for any moderate-to-long course.<\/li>\n<li><strong>Risico op osteoporose<\/strong> &mdash; particularly relevant for patients receiving repeated IM depots or long oral courses.<\/li>\n<li><strong>Glaucoom en cataract<\/strong> &mdash; periorbital injection in particular can raise intraocular pressure; annual ophthalmology review for long-term users.<\/li>\n<li><strong>Psychiatrische voorgeschiedenis<\/strong> &mdash; pulse-dose IV and high-dose oral steroid can trigger mania, depression, psychosis. Use the lowest effective dose; warn the patient and family.<\/li>\n<li><strong>Zwangerschap<\/strong> &mdash; triamcinolone crosses the placenta; considered compatible with pregnancy when indicated for serious maternal disease, but routine elective use should be deferred. <\/li>\n<li><strong>Borstvoeding<\/strong> &mdash; small amounts pass into milk; clinically insignificant at typical anti-inflammatory doses. After IV pulse, defer breastfeeding for 4 hours after a 1 g infusion to minimise infant exposure.<\/li>\n<li><strong>Kinderen<\/strong> &mdash; growth suppression is a real concern with prolonged use; monitor height and weight, use minimum effective dose for minimum duration.<\/li>\n<li><strong>Ouderen<\/strong> &mdash; higher risk of osteoporosis, diabetes, infection, psychiatric effects. Lower doses and shorter durations when possible.<\/li>\n<li><strong>Levende vaccins<\/strong> &mdash; contraindicated at immunosuppressive doses (oral &ge; 16 mg\/day triamcinolone or equivalent for 2+ weeks; IM depot acts as continuous immunosuppressive exposure for 4&ndash;6 weeks per dose). Inactivated vaccines (flu, pneumococcal, COVID-19, recombinant Shingrix) are fine.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Contraindications &mdash; Who Should NOT Receive Kenacort<\/h2>\n<ul>\n<li>Known hypersensitivity to triamcinolone, the vehicle (tablet excipients), or any related corticosteroid<\/li>\n<li>Systemic fungal infection (unless specifically covered by antifungal therapy)<\/li>\n<li>Untreated active bacterial, viral, mycobacterial or parasitic infection without appropriate treatment<\/li>\n<li>Recent live vaccine administration at immunosuppressive doses<\/li>\n<li>Cerebrale malaria (corticostero\u00efden verslechteren de uitkomst)<\/li>\n<li>Ernstige, instabiele psychiatrische aandoening zonder psychiatrische begeleiding (relatief)<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Geneesmiddelinteracties<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Combineren met<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Effect<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Wat te doen<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">NSAID's (ibuprofen, diclofenac, naproxen)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Major additive GI ulceration and bleed risk<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Schrijf een PPI voor; vermijd langdurige combinatie.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Warfarine, DOAC's<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Variable INR change; increased GI bleed risk<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor INR more frequently during dose changes.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Diabetesmedicatie<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Stero\u00efden verhogen de bloedglucose aanzienlijk<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Expect 1.5&ndash;3&times; higher insulin needs during course; up-titrate oral agents.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Antihypertensives, diuretics<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Steroids retain fluid, raise BP<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor BP; up-titrate antihypertensives as needed.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Kaliumverliezende middelen (thiaziden, lisdiuretica, amfotericine)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Additive hypokalaemia &mdash; increases cardiac risk<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Check potassium pre-treatment; supplement as needed.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Sterke CYP3A4-remmers (ketoconazol, ritonavir, clarithromycine)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Raise triamcinolone levels and prolong effect<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Watch for amplified steroid side effects; consider lower dose.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Sterke CYP3A4-induceerders (rifampicine, fenyto\u00efne, carbamazepine, Sint-Janskruid)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Lower triamcinolone levels &mdash; loss of disease control<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">May need 2&ndash;3&times; higher steroid dose; specialist review.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Live vaccines (MMR, varicella, yellow fever, BCG, live nasal flu, live Zostavax)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Risico op gedissemineerde vaccinstam-infectie<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Contraindicated at immunosuppressive doses, and for 3 months after stopping. Inactivated vaccines and recombinant Shingrix are safe.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Digoxine<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Hypokalaemia from steroids increases digoxin toxicity risk<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor potassium and digoxin level.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Other immunosuppressants (methotrexate, azathioprine, cyclosporine, biologics, JAK inhibitors)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Additief infectierisico<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Combinations are common and often necessary &mdash; specialist supervision and infection-prophylaxis consideration.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 class=\"wp-block-heading\">Bewaaradvies<\/h2>\n<ul>\n<li>Bewaren bij kamertemperatuur, <strong>onder 25\u00b0C<\/strong>, beschermd tegen licht en vocht.<\/li>\n<li>Bewaar tabletten in de originele blisterverpakking tot gebruik.<\/li>\n<li>Bewaar niet in de badkamer \u2014 vocht verkort de houdbaarheid.<\/li>\n<li>Buiten bereik van kinderen houden.<\/li>\n<li>Niet gebruiken na de vervaldatum op de verpakking.<\/li>\n<li>Return unused product to a pharmacy for disposal &mdash; do not flush or discard in household waste.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Gerelateerde alternatieven op MedsBase<\/h2>\n<p>Andere medicijnen die worden gebruikt bij ontstekingsremmende en auto-immuunzorg, naast dit product:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/barinat\/\"><strong>Barinat (baricitinib 2 \/ 4 mg) \u2014 JAK1\/2-remmer voor RA<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/tofe\/\"><strong>Tofe (tofacitinib 5 mg) \u2014 JAK1\/3-remmer voor RA, UC, PsA<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/azoran\/\"><strong>Azoran (azathioprine 50 mg) \u2014 klassieke immunosuppressieve DMARD<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/lefuheal\/\"><strong>Lefuheal (leflunomide) \u2014 orale DMARD voor reumato\u00efde artritis<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/conimune-me\/\"><strong>Conimune ME (cyclosporine) - calcineurineremmer<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/wysolone\/\"><strong>Wysolone (prednisolon 5 \/ 10 \/ 20 mg) \u2014 oraal corticostero\u00efd<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/medrol\/\"><strong>Medrol (methylprednisolon 4 \/ 8 \/ 16 mg) \u2014 oraal corticostero\u00efd<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/predniheal\/\"><strong>Predniheal (prednisolon) \u2014 oraal corticostero\u00efd<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/hisone\/\"><strong>Hisone (hydrocortison) \u2014 fysiologisch vervangend stero\u00efd<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/budez-cr\/\"><strong>Budez CR (budesonide) \u2014 darmgericht corticostero\u00efd voor de ziekte van Crohn<\/strong><\/a><\/li>\n<\/ul>\n<p>Ontdek het volledige <a href=\"https:\/\/medsbase.com\/nl\/anti-inflammatory-autoimmune-care\/\">Ontstekingsremmende &amp; Auto-immuunzorg<\/a> category.<\/p>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3 class=\"wp-block-heading\">Why is Kenacort chosen over prednisolone?<\/h3>\n<p>Triamcinolone has almost no mineralocorticoid (sodium- and water-retaining) effect, while prednisolone has a small but clinically relevant one. In a patient with poorly-controlled hypertension, congestive heart failure, severe oedema, or a history of fluid retention on prednisolone, triamcinolone is a sensible alternative at equivalent anti-inflammatory dose. The trade-off is a slightly higher rate of steroid myopathy at high or prolonged dose, which is why prednisolone remains the default for most indications.<\/p>\n<h3 class=\"wp-block-heading\">What is the equivalent dose of Kenacort to prednisolone?<\/h3>\n<p>Triamcinolone 4 mg is roughly equivalent to prednisolone 5 mg, methylprednisolone 4 mg, hydrocortisone 20 mg, and dexamethasone 0.75 mg in anti-inflammatory potency. When switching between oral steroids, use this conversion to keep the anti-inflammatory dose the same.<\/p>\n<h3 class=\"wp-block-heading\">Why must I take Kenacort in the morning?<\/h3>\n<p>Endogenous cortisol peaks between 6 and 9 a.m. Morning dosing mimics this natural pattern, suppresses the HPA axis less than evening dosing, and reduces insomnia. Once-daily morning dosing is standard; twice- or thrice-daily dosing is reserved for severe disease at the cost of more HPA suppression.<\/p>\n<h3 class=\"wp-block-heading\">Why can&#39;t I just stop Kenacort if I feel better?<\/h3>\n<p>After more than 2&ndash;3 weeks of daily dosing, the adrenal glands stop making their own cortisol because the pituitary sees plenty of it arriving from the tablet. If you stop abruptly, the adrenal glands cannot switch back on fast enough &mdash; you have no cortisol for hours to days, which can cause an adrenal crisis (collapse, low blood pressure, severe nausea, confusion, potentially death). Always taper under medical supervision.<\/p>\n<h3 class=\"wp-block-heading\">How do I protect my bones on Kenacort?<\/h3>\n<p>Start calcium 1,000&ndash;1,200 mg\/day + vitamin D 800&ndash;1,000 IU\/day from day one. For courses expected to last more than 3 months at 6 mg\/day or higher, a weekly bisphosphonate (alendronate or risedronate) or annual zoledronic acid should be considered from the start in post-menopausal women and older men &mdash; do not wait for a DEXA scan. Weight-bearing exercise, smoking cessation, moderate alcohol, and adequate protein intake all help.<\/p>\n<h3 class=\"wp-block-heading\">Will Kenacort give me diabetes?<\/h3>\n<p>Corticosteroids raise blood glucose and can unmask latent diabetes or worsen existing diabetes. Expect fasting glucose to rise within days of starting any moderate-dose course. Check fasting glucose or HbA1c before starting; monitor during; be ready to up-titrate oral hypoglycaemics or add temporary insulin. Steroid-induced diabetes from a short course usually resolves within weeks of tapering off; long-term use can cause persistent diabetes.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol on Kenacort?<\/h3>\n<p>Moderate alcohol (up to 1&ndash;2 units\/day) is generally safe on short-to-medium steroid courses, but combined steroid + NSAID + alcohol is a major risk factor for GI bleed. Higher alcohol intake during long-term steroid therapy also increases the risk of avascular necrosis of the hip. Keep alcohol low during any steroid course &mdash; and avoid entirely if taking concomitant NSAIDs or with a history of GI bleed.<\/p>\n<h3 class=\"wp-block-heading\">What if I get an infection while on Kenacort?<\/h3>\n<p>Steroids suppress both the immune response and the outward signs of infection (fever may be blunted, symptoms less obvious). Any unexplained fever, productive cough, new pain, severe fatigue or malaise on Kenacort should be reviewed promptly. During acute illness you may need a temporary DOSE INCREASE (&ldquo;stress dose&rdquo;) rather than a dose reduction &mdash; your prescriber should have given you sick-day rules. Do not stop the steroid when you are ill.<\/p>\n<h3 class=\"wp-block-heading\">Can I have live vaccines on Kenacort?<\/h3>\n<p><strong>Nee, bij immunosuppressieve doseringen.<\/strong> Live vaccines (MMR, varicella, yellow fever, BCG, live nasal flu, live Zostavax) are contraindicated at triamcinolone 16 mg\/day or more for 2 weeks or longer, and for 3 months after stopping. Inactivated vaccines &mdash; annual flu jab, pneumococcal, COVID-19, recombinant Shingrix, HPV &mdash; are fine and recommended. Plan travel vaccinations and Shingrix before starting a prolonged course.<\/p>\n<h3 class=\"wp-block-heading\">What is a steroid card and do I need one?<\/h3>\n<p>A steroid card is a small card you carry that states you are on long-term corticosteroid therapy. It warns emergency clinicians and anaesthetists that you have HPA-axis suppression and may need stress-dose steroid cover during surgery, trauma or severe illness. You should carry one if you have been on any oral corticosteroid for more than 3 weeks, or after any IM depot in the previous 6 weeks. Pharmacies can issue one on request.<\/p>\n<h3 class=\"wp-block-heading\">Waarom bestellen bij MedsBase<\/h3>\n<p>Kenacort is supplied through a WHO-GMP certified manufacturer with full COA documentation. We ship worldwide in plain, discreet packaging, and every order is covered by our <a href=\"\/nl\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance Policy<\/a>. Uw betalingsbeschrijving bij betaling per kaart toont de gereguleerde betalingsverwerker (een gereguleerde kaartbetalingverwerker), nooit \u201cMedsBase\u201d of een medicijnnaam.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Andere ontstekingsremmende en auto-immuun medicijnen<\/h3>\n<p>If Kenacort does not suit your situation, the following options are available in this category:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/tricort\/\">Tricort (Triamcinolone 4 mg, Cipla) \u2014 same molecule, different brand<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/kenacort-injection\/\">Kenacort Injection (Triamcinolone acetonide 10\/40 mg\/mL) \u2014 IM\/IA depot<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/wysolone\/\">Wysolone (Prednisolone 5\/10\/20 mg, Wyeth) \u2014 most-prescribed prednisolone<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/medrol\/\">Medrol (Methylprednisolone 4\/8\/16 mg, Pfizer) \u2014 slightly more potent<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/betnesol-tab\/\">Betnesol Tab (Betamethasone 0.5 mg) \u2014 long-acting fluorinated steroid<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Vermindert ontsteking<br \/>\n\u2705 Relieves itching<br \/>\n\u2705 Behandelt huidaandoeningen<br \/>\n\u2705 Soothes irritation<br \/>\n\u2705 Bevordert genezing<\/p>\n<p>Kenacort contains Triamcinolone.<\/p>","protected":false},"featured_media":60947,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3897,3141,3223],"product_tag":[4723,4725],"class_list":{"0":"post-60946","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-inflammatory-autoimmune-care","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","9":"product_tag-kenacort","10":"product_tag-triamcinolone","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/60946","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=60946"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/60947"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=60946"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=60946"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=60946"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=60946"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}