{"id":61483,"date":"2024-02-28T07:42:59","date_gmt":"2024-02-28T07:42:59","guid":{"rendered":"https:\/\/medsname.com\/t-bact-ointment-2\/"},"modified":"2026-05-01T10:49:16","modified_gmt":"2026-05-01T10:49:16","slug":"t-bact-ointment-2","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/t-bact-ointment-2\/","title":{"rendered":"T-Bact Zalf"},"content":{"rendered":"

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⚡ Quick Answer — What is T-Bact Ointment?<\/h3>\n

T-Bact Zalf<\/strong> bevat mupirocin 2% w\/w<\/strong> as a topical ointment from GlaxoSmithKline — a unique-class antibiotic used for the treatment of impetigo, secondary infection of minor wounds and cuts, infected eczema, folliculitis<\/strong>, en voor nasal MRSA decolonisation<\/strong>. Mupirocin’s mechanism (inhibition of bacterial isoleucyl-tRNA synthetase) is unique — no cross-resistance with any other antibiotic class. This makes it a precious resource against multi-drug-resistant organisms including methicillin-resistant Staphylococcus aureus<\/em> (MRSA)<\/strong>. Apply a thin film 2-3 times daily for a maximum of 7-10 days.<\/strong> Beyond 10 days, the risk of resistance development rises substantially — mupirocin should NOT be used for long-term wound dressing or chronic skin colonisation without microbiological confirmation. Meest voorkomende bijwerkingen:<\/strong> mild burning, stinging, or itching at the application site. Mupirocin is for cutaneous use only<\/strong> — do not apply to mucous membranes, the eye, or use the skin formulation in the nose (a separate nasal-formulation mupirocin exists for MRSA decolonisation).<\/p>\n<\/div>\n

\nWat u krijgt bij MedsBase:<\/strong> WHO-GMP gecertificeerde fabrikant \u00b7 Discrete verpakking \u00b7 Wereldwijde verzending \u00b7 1.400+ geverifieerde klantbeoordelingen<\/a>\n<\/div>\n

\ud83d\udce6 Elke bestelling is gedekt door onze Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n

Waarom bestellen bij MedsBase<\/h3>\n

Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n

What Is T-Bact Ointment?<\/h2>\n

T-Bact Ointment is a topical mupirocin 2% w\/w<\/strong> ointment from GlaxoSmithKline, supplied in a 5 g tube. Mupirocin (formerly known as pseudomonic acid A) was originally isolated from Pseudomonas fluorescens<\/em> in 1971 and entered clinical use in 1985. Internationally branded as Bactroban (GSK), Centany (Medimetriks), Eismycin, Mupirox, Mupiderm, Foban<\/strong>, and many generic versions.<\/p>\n

How Does Mupirocin Work?<\/h2>\n

Mupirocin has a unique mechanism of action<\/strong> not shared by any other antibiotic class:<\/p>\n

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  • Inhibits bacterial isoleucyl-tRNA synthetase (IleRS)<\/strong> — the enzyme that charges tRNA with isoleucine for protein synthesis. Without functional IleRS, bacterial protein synthesis halts and the cell dies.<\/li>\n
  • Selective for bacterial IleRS<\/strong> — mammalian IleRS is structurally different and is not affected at clinical doses, giving mupirocin an excellent safety margin.<\/li>\n
  • Bactericidal at therapeutic concentrations<\/strong> against susceptible Gram-positives (Staphylococcus aureus<\/em> including MRSA, Streptococcus pyogenes<\/em>) and some Gram-negatives. Limited activity against anaerobes and Gram-negative enterics.<\/li>\n
  • No cross-resistance<\/strong> with beta-lactams, macrolides, fluoroquinolones, tetracyclines, glycopeptides, or any other antibiotic class — this is mupirocin’s great clinical strength against MRSA.<\/li>\n<\/ul>\n

    Mupirocin is rapidly inactivated in serum (half-life <30 min) and has minimal systemic absorption from intact skin — it is purely a topical antibiotic. Visible improvement of skin infection typically begins within 2-3 days; full clearance over the 7-10 day treatment course.<\/p>\n

    When T-Bact Ointment Is Used<\/h2>\n

    Gelicentieerde indicaties:<\/strong><\/p>\n

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    • Impetigo<\/strong> (veroorzaakt door Staphylococcus aureus<\/em> of Streptococcus pyogenes<\/em>) — first-line topical antibiotic for limited-extent impetigo<\/li>\n
    • Secondary infection of minor wounds, cuts, abrasions, lacerations, and burns<\/strong><\/li>\n
    • Infected dermatoses<\/strong> — secondarily-infected eczema, contact dermatitis<\/li>\n
    • Folliculitis (bacterial)<\/strong><\/li>\n
    • Furunculosis<\/strong> (boils) — uncomplicated<\/li>\n<\/ul>\n

      Off-label \/ specialist uses:<\/strong><\/p>\n

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      • MRSA \/ MSSA nasal decolonisation<\/strong> — using the dedicated 2% nasal ointment formulation (NOT this skin formulation), 2-3× daily for 5 days. Standard pre-operative protocol for cardiac, orthopaedic, and other high-risk surgeries.<\/li>\n
      • Recurrent furunculosis prevention<\/strong> — nasal decolonisation + intermittent topical to colonised skin sites<\/li>\n
      • Outbreak control<\/strong> in healthcare settings (NICU, dialysis units)<\/li>\n<\/ul>\n

        Mupirocin is NIET<\/strong> for: deep abscesses (need surgical drainage), cellulitis (needs systemic antibiotic), erysipelas, infected diabetic foot ulcers (multi-organism, needs systemic + culture-guided therapy), or fungal\/viral skin infections.<\/p>\n

        T-Bact Ointment Dosage and How to Apply<\/h2>\n
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        1. Handen wassen<\/strong> voor en na het aanbrengen.<\/li>\n
        2. Clean the affected area gently<\/strong> with mild soap and water; pat dry with a clean towel.<\/li>\n
        3. Apply a small amount of T-Bact Ointment<\/strong> (a pea-sized blob covers a 2-3 cm lesion) to the infected area; rub in gently.<\/li>\n
        4. Cover with a sterile dressing if needed<\/strong> — particularly for impetigo on exposed skin (face, hands) to prevent transmission and reduce auto-inoculation.<\/li>\n
        5. Apply 2-3 times daily for up to 7-10 days<\/strong>.<\/li>\n
        6. If no improvement after 3-5 days, see your doctor — the infection may be caused by a mupirocin-resistant organism, may be a different microbiological process (fungal, viral), or may need systemic antibiotics.<\/li>\n
        7. Do NOT use beyond 10 days<\/strong> — resistance development risk rises sharply. If chronic colonisation is the issue, discuss longer-term decolonisation strategies with your doctor (alternating antiseptics, behavioural measures).<\/li>\n<\/ol>\n

          Kinderen:<\/strong> safe from age 2 months under medical supervision. Same dosing schedule.<\/p>\n

          Zwangerschap:<\/strong> minimal systemic absorption; generally considered safe. Borstvoeding:<\/strong> do not apply to nipples without specialist advice.<\/p>\n

          MRSA Resistance & Stewardship<\/h2>\n

          Mupirocin is one of the few topical antibiotics with reliable activity against methicillin-resistant Staphylococcus aureus<\/em> (MRSA)<\/strong> — including community-acquired (CA-MRSA) and hospital-acquired (HA-MRSA) strains. This makes it valuable but also vulnerable to misuse-driven resistance.<\/p>\n

          Mupirocin resistance comes in two forms:<\/strong><\/p>\n