{"id":61630,"date":"2024-03-03T08:48:02","date_gmt":"2024-03-03T08:48:02","guid":{"rendered":"https:\/\/medsname.com\/nailrox-nail-lacquer\/"},"modified":"2026-04-30T10:23:33","modified_gmt":"2026-04-30T10:23:33","slug":"nailrox-nail-lacquer","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/nailrox-nail-lacquer\/","title":{"rendered":"Nailrox Nail Lacquer"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 20px;margin:18px 0;border-radius:6px;\">\n<h3 style=\"margin-top:0;\">\ud83d\udca1 Snel antwoord<\/h3>\n<p style=\"margin-bottom:0;\">Nailrox Nail Lacquer is ciclopirox 8% w\/v medicated nail lacquer \u2014 a hydroxypyridinone antifungal (mechanism distinct from azoles, allylamines, and morpholines) for onychomycosis caused by Trichophyton rubrum and T. mentagrophytes. Daily application during the first week then progressively less often (week 2 every 2 days, week 3+ once weekly), with weekly removal using nail polish remover. Treatment up to 48 weeks for toenails. Cure rates with topical alone are modest (~30%); combination with oral terbinafine improves outcomes.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f5f5f5;border:1px solid #e1e1e1;padding:18px 22px;margin:24px 0;border-radius:8px;display:flex;flex-wrap:wrap;justify-content:space-around;gap:16px;align-items:center;font-size:0.95em;\">\n<div style=\"text-align:center;flex:1;min-width:140px;\">\ud83c\udfed<br \/><strong>WHO-GMP<\/strong><br \/>gecertificeerde fabrikant<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n<div style=\"text-align:center;flex:1;min-width:140px;\">\ud83d\udce6<br \/><strong>Discrete verpakking<\/strong><br \/>ongemarkeerde envelop<\/div>\n<div style=\"text-align:center;flex:1;min-width:140px;\">\ud83c\udf0d<br \/><strong>Wereldwijde verzending<\/strong><br \/>naar de meeste landen<\/div>\n<div style=\"text-align:center;flex:1;min-width:140px;\">\u2b50<br \/><strong>1.400+ klanten<\/strong><br \/><a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">lees beoordelingen<\/a><\/div>\n<\/div>\n<h2>\ud83d\udd12 Why order Nailrox Nail Lacquer from MedsBase<\/h2>\n<ul>\n<li><strong>WHO-GMP gecertificeerde fabrikant<\/strong> \u2014 afkomstig uit een gereguleerde faciliteit, complete verpakking met batchnummer en vervaldatum.<\/li>\n<li><strong>Discrete verpakking<\/strong> \u2014 gewone envelop, geen medicatienaam aan de buitenkant.<\/li>\n<li><strong>Wereldwijde verzending<\/strong> naar de meeste landen met <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance<\/a>.<\/li>\n<li><strong>Loyaliteitspunten<\/strong> \u2014 1 punt per $1 uitgegeven (peptiden\/verzendkosten uitgezonderd); 100 punten = $5 korting op uw volgende bestelling.<\/li>\n<\/ul>\n<h2 id=\"uses\">Toepassingen<\/h2>\n<p>Nailrox Nail Lacquer (ciclopirox 8% w\/v nail lacquer, Glenmark) is approved for mild-to-moderate onychomycosis caused by dermatophytes (Trichophyton rubrum, T. mentagrophytes). Like amorolfine, it is most effective for distal-edge disease that does not involve the nail matrix.<\/p>\n<h2 id=\"how-to-apply\">How to apply \u2014 schedule matters<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:0.95em;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">Week<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">Frequentie<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Week 1<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Apply once daily, ideally at bedtime<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Week 2<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Apply every other day<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Week 3 onwards<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Apply once weekly<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Once a week<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Remove existing lacquer with nail polish remover, file the nail, then re-apply<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul>\n<li>File rough surface of the affected nails.<\/li>\n<li>Apply a thin layer to the entire nail and 5 mm of surrounding skin (drug also penetrates lateral nail folds).<\/li>\n<li>Wait 30 seconds to let it dry.<\/li>\n<li>Once weekly: use nail polish remover (acetone or ethyl acetate) to remove all built-up lacquer, file rough surface, then re-apply.<\/li>\n<li>Treatment may continue up to 48 weeks for toenails.<\/li>\n<\/ul>\n<h2 id=\"mechanism\">Hoe het werkt<\/h2>\n<p>Ciclopirox is a hydroxypyridinone antifungal \u2014 chemically distinct from azoles, allylamines, and morpholines. It chelates trivalent metal cations (iron, aluminium) required by fungal mitochondrial enzymes. The result is impaired energy production and reduced uptake of essential precursors. Active against dermatophytes, Candida, Malassezia, and some bacteria \u2014 broader spectrum than most other topical antifungals. Penetrates the nail plate over weeks of repeat application.<\/p>\n<h2 id=\"side-effects\">Bijwerkingen<\/h2>\n<ul>\n<li>Common \u2014 periungual erythema, mild burning at application, brittleness or shape change of the affected nail.<\/li>\n<li>Uncommon \u2014 contact dermatitis, onycholysis.<\/li>\n<li>Rare \u2014 severe contact allergy.<\/li>\n<\/ul>\n<h2 id=\"pregnancy\">Zwangerschap &amp; borstvoeding<\/h2>\n<p>Limited data. Minimal systemic absorption. Onychomycosis is not life-threatening \u2014 many clinicians defer treatment until after pregnancy. Topical ciclopirox use in breastfeeding is generally considered low-risk; avoid hand-to-mouth contact with the infant after application.<\/p>\n<h3 class=\"wp-block-heading\">Waarom bestellen bij MedsBase<\/h3>\n<ul>\n<li><strong>WHO-GMP gecertificeerde fabrikant<\/strong> \u2014 afkomstig van een gereguleerde faciliteit, complete verpakking met batchnummer en vervaldatum.<\/li>\n<li><strong>Discrete verpakking<\/strong> \u2014 gewone envelop, geen medicatienaam aan de buitenkant.<\/li>\n<li><strong>Wereldwijde verzending<\/strong> met <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij kosteloos een nieuwe zending (onder voorbehoud van de beleidstermen).<\/li>\n<li><strong>Loyaliteitspunten<\/strong> \u2014 1 punt per<br \/>\n<h2>Veelgestelde vragen besteed (exclusief peptiden); 100 punten =  korting.<\/li>\n<\/ul>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3>Daily then weekly \u2014 why the change?<\/h3>\n<p>First-week loading establishes drug levels in the nail. From week 3 the lacquer accumulates a depot in the nail plate and weekly application is enough to maintain fungicidal levels. This is also why the weekly polish-remover step matters \u2014 clears the built-up film so a fresh application can penetrate.<\/p>\n<h3>How long until I can stop?<\/h3>\n<p>Depends on response. Toenails: up to 48 weeks of treatment, then assess. Fingernails: typically 6 months. The visible nail may not look fully normal even at the end of treatment \u2014 the dead infected portion grows out for months after.<\/p>\n<h3>Ciclopirox vs amorolfine \u2014 which is better?<\/h3>\n<p>Cure rates from topical-only therapy are similar (modest ~30\u201340%) and both are inferior to oral terbinafine for moderate-to-severe disease. Choose by leaflet preference (daily-then-weekly ciclopirox vs. weekly amorolfine) and patient adherence.<\/p>\n<h3>Can I combine with oral terbinafine?<\/h3>\n<p>Yes \u2014 combination (oral terbinafine 12 weeks + topical ciclopirox 9\u201312 months) gives higher cure rates than either alone, especially for thick or matrix-involved toenail disease.<\/p>\n<h3>Why all the polish-remover faff?<\/h3>\n<p>Ciclopirox lacquer is a film-forming polymer. Layers of it build up. Once weekly removal with acetone-based polish remover lets a fresh layer penetrate the underlying nail. Skipping this step makes the next application sit on old polymer rather than soaking into the nail.<\/p>\n<h3>Is Nailrox Nail Lacquer the same as Penlac?<\/h3>\n<p>Yes \u2014 Penlac (in the US) is the original brand. Nailrox Nail Lacquer contains the same active ingredient (ciclopirox 8%), manufactured by Glenmark under WHO-GMP. Bioequivalent.<\/p>\n<h3>What if my nail is very thick?<\/h3>\n<p>See a podiatrist for nail debridement before starting. Topical lacquer cannot penetrate a 5-mm-thick nail. Combine debridement + oral terbinafine + topical lacquer for the best outcome.<\/p>\n<h3>Can I get a pedicure during treatment?<\/h3>\n<p>Yes \u2014 but use your own files and instruments. Salon files used on infected nails spread fungus to other clients. Disposable single-use files are best.<\/p>\n<h3>Why does my nail look worse after a few weeks?<\/h3>\n<p>Brittleness and surface roughness are common during treatment; the drug disrupts the nail surface as it penetrates. Continue the schedule. As new healthy nail grows in, the appearance improves.<\/p>\n<h3>Can I wear cosmetic nail polish over the lacquer?<\/h3>\n<p>Generally not advised on top of ciclopirox \u2014 most leaflets recommend keeping the medicated lacquer alone. If you want cosmetic polish for an occasion, remove the medicated film, apply cosmetic polish for the day, then remove and re-start the schedule.<\/p>\n<h2 id=\"storage\">Opslag<\/h2>\n<p>Store the bottle tightly capped at 15\u201325 \u00b0C, away from heat and flames (the solvent is flammable). Keep out of reach of children. Do not use after expiry.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2>Andere antischimmelmiddelen die u mogelijk interesseren<\/h2>\n<p>If Nailrox Nail Lacquer is unavailable, here are alternatives.<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/zimig\/\"><strong>Zimig (terbinafine 250 mg)<\/strong><\/a> \u2014 Eerste keuze oraal middel voor dermatofyten onychomycose; hogere genezingspercentage.<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/sporanox-capsule\/\"><strong>Sporanox (itraconazol 100 mg)<\/strong><\/a> \u2014 Puls-therapie als alternatief voor onychomycose.<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/loceryl-nail-liq\/\"><strong>Loceryl (amorolfine 5% nagellak)<\/strong><\/a> \u2014 Andere topische nagellak (morfoline), wekelijkse toepassing.<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/nailrox-nail-lacquer\/\"><strong>Nailrox (ciclopirox 8% nagellak)<\/strong><\/a> \u2014 Andere topische nagellak (hydroxypyridinon).<\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/keto-cream\/\"><strong>Keto Cream (ketoconazol 2%)<\/strong><\/a> \u2014 Bij gelijktijdige tinea pedis.<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:12px 18px;margin:24px 0;font-size:0.95em;\"><strong>Medisch disclaimer.<\/strong> Deze pagina bevat productinformatie voor volwassenen die antischimmelmedicijnen voor persoonlijk gebruik bestellen. Het is geen vervanging voor individueel medisch advies. Bespreek het juiste antischimmelmiddel, de dosering en de behandelduur met een gekwalificeerde clinicus \u2014 vooral als u leveraandoeningen heeft, zwanger bent of borstvoeding geeft, warfarine gebruikt, een statine gebruikt, immunosuppressiva gebruikt of een schimmelnagelinfectie heeft die een andere diagnose kan zijn (psoriasis, lichen planus, trauma).<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u2705 Fights nail fungus<br \/>\n\u2705 Prevents fungal growth<br \/>\n\u2705 Versterkt nagels<br \/>\n\u2705 Promotes nail health<br \/>\n\u2705 Easy topical application<\/p>\n<p>Nailrox Nail Lacquer contains Ciclopirox.<\/p>","protected":false},"featured_media":61631,"comment_status":"closed","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3501,3642,3141,3504,3342],"product_tag":[5070,5071,5072],"class_list":{"0":"post-61630","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-fungal","7":"product_cat-beauty-skin-care","8":"product_cat-category-overview","9":"product_cat-fungal-infection-treatment","10":"product_cat-general-health","11":"product_tag-ciclopirox","12":"product_tag-nailrox","13":"product_tag-nailrox-nail-lacquer","15":"first","16":"instock","17":"shipping-taxable","18":"purchasable","19":"product-type-variable","20":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/61630","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=61630"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/61631"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=61630"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=61630"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=61630"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=61630"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}