{"id":61710,"date":"2024-03-05T14:54:47","date_gmt":"2024-03-05T14:54:47","guid":{"rendered":"https:\/\/medsname.com\/dutas-t\/"},"modified":"2026-05-01T05:31:51","modified_gmt":"2026-05-01T05:31:51","slug":"dutas-t","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/dutas-t\/","title":{"rendered":"Dutas T"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:18px 0;border-radius:4px;\">\n<p style=\"margin:0 0 8px 0;\"><strong>\ud83d\udca1 Snel antwoord<\/strong><\/p>\n<p style=\"margin:0;\"><strong>Dutas-T<\/strong> combineert <strong>tamsulosin 0.4 mg<\/strong> (an alpha-blocker for immediate urinary symptom relief) with <strong>dutasteride 0.5 mg<\/strong> (a dual 5-alpha-reductase inhibitor that shrinks the prostate over 3\u20136 months). This dual-MOA single-capsule approach is preferred for men with moderate\u2013severe BPH, enlarged prostates (&gt;40 mL), or at risk of acute urinary retention. Once-daily dosing.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Wat u krijgt bij MedsBase:<\/strong> WHO-GMP gecertificeerde fabrikant \u00b7 Discrete verpakking \u00b7 Wereldwijde verzending \u00b7 1.400+ geverifieerde <a href=\"https:\/\/medsbase.com\/nl\/reviews\/\">klantbeoordelingen<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Elke bestelling is gedekt door onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n<h3>Waarom bestellen bij MedsBase<\/h3>\n<p>Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n<div style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.95em;\">\n<strong>\ud83d\udd12 Waarom bestellen bij MedsBase:<\/strong> Geverifieerde echte fabrikantlevering \u00b7 Discrete wereldwijde verzending \u00b7 Veilig afrekenen (creditcard, crypto) \u00b7 Beoordeeld met 4.9\u2605 door 1.400+ klanten\n<\/div>\n<h2><strong>What Is Dutas-T?<\/strong><\/h2>\n<p>Dutas-T is a fixed-dose combination capsule containing <strong>tamsulosin hydrochloride 0.4 mg + dutasteride 0.5 mg<\/strong>. The combination attacks BPH via two complementary mechanisms:<\/p>\n<ul>\n<li><strong>Tamsulosin (alpha-1A blocker):<\/strong> relaxes prostate and bladder-neck smooth muscle \u2014 rapid symptom relief within 1\u20132 weeks<\/li>\n<li><strong>Dutasteride (dual 5-ARI):<\/strong> blocks both type-1 and type-2 5-alpha-reductase enzymes, reducing DHT by ~90% and shrinking the prostate over 3\u20136 months<\/li>\n<\/ul>\n<p>The CombAT (Combination of Avodart and Tamsulosin) trial showed this combination reduced BPH progression, acute urinary retention, and surgery need more than either drug alone. Available strength: <strong>0.4 mg tamsulosin + 0.5 mg dutasteride<\/strong>. Manufactured by Dr. Reddy&#039;s Laboratories.<\/p>\n<h2><strong>Genitale herpes (eerste episode):<\/strong><\/h2>\n<ul>\n<li><strong>Moderate\u2013severe BPH<\/strong> with enlarged prostate (&gt;30\u201340 mL) and moderate\u2013severe LUTS<\/li>\n<li><strong>Men at risk of acute urinary retention<\/strong> or needing BPH-related surgery<\/li>\n<li><strong>Men in whom tamsulosin alone has plateaued<\/strong> after 3\u20136 months and further progression prevention is desired<\/li>\n<\/ul>\n<h2><strong>Hoe in te nemen<\/strong><\/h2>\n<ol>\n<li>Swallow the capsule whole with water \u2014 do not crush, chew, or open. The inner contents leak onto skin and this risks exposure to women of reproductive age (dutasteride is teratogenic via skin).<\/li>\n<li>Take once daily, roughly 30 minutes after the same meal each day (usually breakfast).<\/li>\n<li>Tamsulosin effect begins within days; the dutasteride effect builds over 3\u20136 months. Peak combination benefit at <strong>6\u201312 months<\/strong>.<\/li>\n<li>Do not skip doses \u2014 dutasteride has a 5-week half-life but tamsulosin effect is daily.<\/li>\n<li>Tell any ophthalmologist before cataract surgery (tamsulosin IFIS risk).<\/li>\n<li>Tell any clinician ordering PSA \u2014 dutasteride halves PSA readings.<\/li>\n<\/ol>\n<h2><strong>Bijwerkingen<\/strong><\/h2>\n<p><strong>Tamsulosin-related:<\/strong> dizziness, headache, abnormal ejaculation, rhinitis, asthenia.<\/p>\n<p><strong>Dutasteride-related:<\/strong> decreased libido (~4%), erectile dysfunction (~4%), reduced ejaculate volume, gynecomastia, mood changes.<\/p>\n<p><strong>Ernstig (zeldzaam):<\/strong> orthostatic hypotension, Intraoperative Floppy Iris Syndrome, priapism, persistent sexual side effects after discontinuation (PFS-equivalent).<\/p>\n<h2><strong>Who Should Not Take Dutas-T<\/strong><\/h2>\n<ul>\n<li><strong>Vrouwen in de vruchtbare leeftijd<\/strong> \u2014 dutasteride is teratogenic. Do not handle broken capsules.<\/li>\n<li>Men with severe hepatic impairment (both components hepatically cleared)<\/li>\n<li>Orthostatic hypotension history<\/li>\n<li>Planned cataract \/ glaucoma surgery without telling ophthalmologist<\/li>\n<li>Strong CYP3A4 inhibitor co-therapy (ketoconazole, ritonavir)<\/li>\n<li>Known hypersensitivity to tamsulosin, dutasteride, finasteride, or sulphonamides<\/li>\n<\/ul>\n<h2><strong>Geneesmiddelinteracties<\/strong><\/h2>\n<ul>\n<li><strong>PDE5-remmers<\/strong>: tamsulosin + sildenafil\/vardenafil = additive hypotension. Tadalafil 5 mg daily is often the pragmatic choice.<\/li>\n<li><strong>Sterke CYP3A4-remmers<\/strong>: raise both tamsulosin and dutasteride levels.<\/li>\n<li><strong>Andere alfa-blokkers<\/strong>: avoid \u2014 additive effect.<\/li>\n<li><strong>PSA-test<\/strong>: dutasteride halves PSA. Double the measured value for interpretation.<\/li>\n<\/ul>\n<h2><strong>Combination vs Monotherapy<\/strong><\/h2>\n<p>The CombAT trial (4-year outcomes) showed combination therapy reduced BPH clinical progression by ~66% vs dutasteride alone and ~41% vs tamsulosin alone. Combination is preferred when prostate is enlarged (&gt;30\u201340 mL) or PSA is elevated, suggesting ongoing glandular growth. For smaller prostates with pure symptom dominance, tamsulosin monotherapy is often sufficient.<\/p>\n<p>Zie ook: <a href=\"https:\/\/medsbase.com\/nl\/urimax-f\/\">Urimax-F<\/a> (tamsulosin + finasteride alternative) and our <a href=\"https:\/\/medsbase.com\/nl\/finasteride-vs-dutasteride\/\">Finasteride versus Dutasteride Gids<\/a>.<\/p>\n<h2><strong>Opslag<\/strong><\/h2>\n<p>Store at room temperature (15\u201330 \u00b0C \/ 59\u201386 \u00b0F), away from moisture and heat. Do not refrigerate. Keep in original blister. Keep away from women of reproductive age.<\/p>\n<h2 id=\"faqs\">Veelgestelde vragen<\/h2>\n<h3 class=\"wp-block-heading\">Why the combination pill?<\/h3>\n<p>Tamsulosin and dutasteride attack BPH by different mechanisms \u2014 smooth-muscle relaxation and DHT suppression. Combination therapy reduces BPH progression more than either drug alone (CombAT trial).<\/p>\n<h3 class=\"wp-block-heading\">How soon will symptoms improve?<\/h3>\n<p>Tamsulosin gives urinary symptom relief within 1\u20132 weeks. Dutasteride takes 3\u20136 months for prostate shrinkage. Full combination benefit is seen at 6\u201312 months.<\/p>\n<h3 class=\"wp-block-heading\">Is there a size below which combination is unnecessary?<\/h3>\n<p>For prostates under 30 mL without risk factors, tamsulosin monotherapy often suffices. Combination is strongest for prostates 30 mL and above or men with elevated PSA, bothersome symptoms, and BPH-progression risk factors.<\/p>\n<h3 class=\"wp-block-heading\">What about sexual side effects?<\/h3>\n<p>The dutasteride component contributes decreased libido (~4%) and erectile dysfunction (~4%) risk. The tamsulosin component contributes retrograde ejaculation. Discuss risk-benefit with a clinician, particularly if sexual function is a priority.<\/p>\n<h3 class=\"wp-block-heading\">Can I stop taking Dutas-T abruptly?<\/h3>\n<p>No \u2014 BPH is progressive and symptoms return over weeks to months. Dutasteride has a 5-week half-life, so its effect clears slowly; tamsulosin effect ends within days. For safe discontinuation, discuss with a clinician.<\/p>\n<h3 class=\"wp-block-heading\">Can I combine Dutas-T with a PDE5 inhibitor?<\/h3>\n<p>With care. Tamsulosin + sildenafil\/vardenafil = additive hypotension risk. Tadalafil 5 mg daily is often preferred \u2014 it also treats BPH symptoms on its own.<\/p>\n<h3 class=\"wp-block-heading\">Hoe zit het met PSA-monitoring?<\/h3>\n<p>Dutasteride halves PSA readings. Always tell your clinician you are on Dutas-T before any PSA test. Convention is to double the measured PSA for interpretation.<\/p>\n<h3 class=\"wp-block-heading\">Will Dutas-T prevent prostate cancer?<\/h3>\n<p>Not directly. The REDUCE trial suggested dutasteride reduced low-grade prostate cancer risk but slightly raised detection of high-grade tumours. Use dutasteride for BPH indications \u2014 not as prostate cancer prophylaxis.<\/p>\n<h3 class=\"wp-block-heading\">Gerelateerde BPH-producten<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/urimax\/\">Urimax (Tamsulosin 0.2 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/urimax-capsule\/\">Urimax Capsule (Tamsulosine 0,4 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/tamsuheal\/\">Tamsuheal (Tamsulosine 0,4 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/monolosin\/\">Monolosin (Tamsulosine 0,4 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/urimax-f\/\">Urimax-F (Tamsulosine + Finasteride)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/nafodil\/\">Nafodil (Naftopidil 50 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/deetor\/\">Deetor (Dutasteride 0,5 mg)<\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.9em;\">\n<p style=\"margin:0;\"><strong>\u2695\ufe0f Medische disclaimer:<\/strong> Deze informatie is educatief en vervangt geen medisch advies. Raadpleeg een clinicus voordat u met een medicatie begint, stopt of wijzigt. Voorschriftproducten mogen alleen onder medisch toezicht worden gebruikt.<\/p>\n<\/div>\n<p data-mb-link-target=\"minoxytop\" data-mb-anchor-variant=\"v2\" style=\"margin-top:1em;font-size:0.95em;color:#444;border-left:3px solid #2c7cb0;padding:0.5em 0.75em;background:#f4f8fb;\"><strong>Zie ook:<\/strong> <a href=\"https:\/\/medsbase.com\/nl\/minoxytop\/\"><strong>oral minoxidil (Minoxytop)<\/strong><\/a> \u2014 oraal minoxidil voor non-responders op topische behandeling \u2014 Curatio Healthcare 1,25 \/ 2,5 \/ 5 mg tabletten.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Gerelateerde alternatieven<\/h3>\n<p>Andere producten in <strong>Mannelijke gezondheid<\/strong> die klanten ook bekijken:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nl\/poxet\/\">Poxet<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/zhewitra-oral-jelly\/\">Zhewitra Oral Jelly<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/vidalista-professional\/\">Vidalista Professional<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/filitra-professional\/\">Filitra Professional<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nl\/p-force-fort\/\">P-Force Fort<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Verbeterde urinestroom<br \/>\n\u2705 Reduces prostate size<br \/>\n\u2705 Verlicht urinewegsymptomen<br \/>\n\u2705 Treats benign prostatic hyperplasia<br \/>\n\u2705 Enhances prostate health<\/p>\n<p>Dutas T contains Tamsulosin and Dutasteride.<\/p>","protected":false},"featured_media":61711,"comment_status":"closed","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3202,3141,3142],"product_tag":[5081,3474,3473],"class_list":{"0":"post-61710","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-benign-prostatic-hyperplasia-bph-treatment","7":"product_cat-category-overview","8":"product_cat-mens-health","9":"product_tag-dutas-t","10":"product_tag-dutasteride","11":"product_tag-tamsulosin","13":"first","14":"instock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product\/61710","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/comments?post=61710"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media\/61711"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/media?parent=61710"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_brand?post=61710"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat?post=61710"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_tag?post=61710"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}