{"id":64815,"date":"2024-10-29T13:55:17","date_gmt":"2024-10-29T13:55:17","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&p=64815"},"modified":"2026-05-10T08:48:12","modified_gmt":"2026-05-10T08:48:12","slug":"niclosig","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/niclosig\/","title":{"rendered":"Niclosig"},"content":{"rendered":"

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Quick Answer — What is Niclosig?<\/h3>\n
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Niclosig<\/strong> is niclosamide 500 mg chewable<\/strong> van Sigmund Promedia<\/strong>. Niclosamide is the WHO Essential Medicine for intestinal tapeworm<\/strong> (Taenia saginata, Taenia solium intestinal-form, Hymenolepis nana, Diphyllobothrium latum). Standard adult dose: 2 g (4 tablets) as a single dose<\/strong>, chewed thoroughly and swallowed with a small amount of water on an empty stomach.<\/p>\n<\/div>\n<\/div>\n

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Waarom bestellen bij MedsBase<\/h3>\n

Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n

What is Niclosig?<\/h2>\n

Niclosig<\/strong> is niclosamide 500 mg chewable from Sigmund Promedia<\/strong>. Niclosamide is a salicylanilide-class anthelmintic with a niche but irreplaceable role: it is the cleanest, most reliable single-dose treatment for intestinal cestodes<\/strong> (tapeworms). It is on the WHO Model List of Essential Medicines and has been used continuously since the 1960s.<\/p>\n

Werkingsmechanisme<\/h2>\n

Niclosamide uncouples oxidative phosphorylation<\/strong> in the tapeworm scolex (head). This depletes parasite ATP, paralyses the scolex, and disrupts its grip on the gut wall. The worm is then partially digested by host enzymes — you may see fragmented proglottids in stool rather than an intact worm. Niclosamide is essentially not absorbed from the gut (< 5%), which is therapeutically perfect: high luminal concentration, near-zero systemic exposure.<\/p>\n

Niclosig indications and dose<\/h2>\n\n\n\n\n\n\n\n\n
Indicatie<\/th>\nDosering<\/th>\nSchema<\/th>\n<\/tr>\n<\/thead>\n
Beef tapeworm (Taenia saginata)<\/td>\n2 g (4 tablets)<\/td>\nSingle dose, chewed on empty stomach<\/td>\n<\/tr>\n
Pork tapeworm intestinal form (Taenia solium)<\/td>\n2 g (4 tablets)<\/td>\nSingle dose; consider laxative 2 h post-dose to reduce theoretical cysticercosis risk<\/td>\n<\/tr>\n
Fish tapeworm (Diphyllobothrium latum)<\/td>\n2 g (4 tablets)<\/td>\nEenmalige dosis<\/td>\n<\/tr>\n
Dwarf tapeworm (Hymenolepis nana)<\/td>\n2 g day 1, then 1 g daily × 6 days<\/td>\n7-day course<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Chew the tablets thoroughly<\/strong>, then swallow with a small amount of water. Take on an empty stomach in the morning, or after a light breakfast. For Taenia solium specifically, some clinicians give a saline laxative 2 h after the dose to evacuate dead proglottids and reduce the (rare) theoretical risk of egg release into the gut and resulting cysticercosis.<\/p>\n

Cysticercosis is a separate disease.<\/strong> Niclosamide treats intestinal<\/em> tapeworm. Neurocysticercosis<\/strong> (Taenia solium larval cysts in the CNS) is treated with albendazole or praziquantel under specialist supervision with imaging and concomitant steroids — not with niclosamide. Headache, seizures, or focal neurological signs in a tapeworm patient need urgent imaging.<\/div>\n

Bijwerkingen<\/h2>\n