{"id":66697,"date":"2025-05-01T13:11:44","date_gmt":"2025-05-01T13:11:44","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&p=66697"},"modified":"2026-05-10T08:48:12","modified_gmt":"2026-05-10T08:48:12","slug":"dicaris-adults-tablet","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/dicaris-adults-tablet\/","title":{"rendered":"Dicaris Adults Tablet"},"content":{"rendered":"

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Quick Answer — What is Dicaris Adults Tablet?<\/h3>\n
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Dicaris Adults Tablet<\/strong> is levamisole 150 mg<\/strong> van Janssen<\/strong>. Levamisole is both an anthelmintic<\/strong> (first-line for ascariasis worldwide before albendazole displaced it) and an immunomodulator<\/strong> used in steroid-dependent or frequently-relapsing nephrotic syndrome to reduce relapse rate. Standard adult anthelmintic dose: 150 mg single dose<\/strong>; immunomodulatory dose: 2.5 mg\/kg every other day in nephrotic syndrome.<\/p>\n<\/div>\n<\/div>\n

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Waarom bestellen bij MedsBase<\/h3>\n

Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen \u2014 geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor \u2014 nooit \u201cMedsBase\u201d of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.<\/p>\n

What is Dicaris Adults Tablet?<\/h2>\n

Dicaris Adults Tablet<\/strong> bevat levamisole 150 mg<\/strong> van Janssen<\/strong>. Originally developed as a veterinary anthelmintic, levamisole was widely used in human medicine for ascariasis from the 1960s until albendazole and mebendazole displaced it as first-line. It retains an important second indication: immunomodulation in childhood nephrotic syndrome<\/strong>, where it reduces relapse frequency in steroid-dependent disease and lets clinicians reduce cumulative steroid dose.<\/p>\n

Werkingsmechanisme<\/h2>\n

As an anthelmintic, levamisole is a nicotinic acetylcholine receptor agonist<\/strong> on parasite muscle, causing spastic paralysis (similar mechanism to pyrantel). The paralysed worm is passed in stool.<\/p>\n

As an immunomodulator, levamisole appears to restore depressed cell-mediated immunity<\/strong> — it enhances T-cell function, monocyte and macrophage activity, and natural killer cell response. The exact mechanism in nephrotic syndrome remains incompletely understood but the clinical effect (reduced relapse) is well-established in randomised trials.<\/p>\n

Dicaris Adults Tablet indications and dose<\/h2>\n\n\n\n\n\n\n\n\n
Indicatie<\/th>\nDosering<\/th>\nSchema<\/th>\n<\/tr>\n<\/thead>\n
Ascariasis (adults)<\/td>\n150 mg<\/td>\nEenmalige dosis<\/td>\n<\/tr>\n
Ascariasis (children)<\/td>\n2.5 mg\/kg<\/td>\nEenmalige dosis<\/td>\n<\/tr>\n
Hookworm (light burden)<\/td>\n150 mg<\/td>\nSingle dose, repeat at 7 days if needed<\/td>\n<\/tr>\n
Steroid-dependent nephrotic syndrome (specialist)<\/td>\n2.5 mg\/kg<\/td>\nEvery other day for 12–24 months under nephrologist supervision<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Take with or after a meal to reduce nausea.<\/p>\n

Specialist supervision for nephrotic syndrome.<\/strong> Long-course levamisole for nephrotic syndrome requires nephrology supervision. Mandatory neutrophil monitoring (FBC every 4–6 weeks for the first 6 months, then every 3 months) is essential because of the well-described risk of agranulocytosis. Stop immediately at signs of infection or oral ulceration.<\/div>\n

Bijwerkingen<\/h2>\n