{"id":68942,"date":"2026-03-03T07:07:09","date_gmt":"2026-03-03T07:07:09","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&p=68942"},"modified":"2026-05-21T07:14:11","modified_gmt":"2026-05-21T07:14:11","slug":"epitalon","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/epitalon\/","title":{"rendered":"Epitalon"},"content":{"rendered":"

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Quick Answer \u2014 What is Epitalon?<\/h3>\n

Epitalon<\/strong> (Ala-Glu-Asp-Gly, AEDG) is a synthetic tetrapeptide analog of a natural pineal-gland peptide. Central to Vladimir Khavinson’s Russian longevity-research programme, it is studied for effects on telomere length, circadian rhythm, and gene-expression profiles in aging research. Supplied in 10\u00a0mg and 50\u00a0mg lyophilized vials for laboratory research use only.<\/p>\n<\/div>\n

Wat u krijgt bij MedsBase:<\/strong> Onderzoekskwaliteit lyofiliseerde peptiden \u00b7 HPLC \u226599% zuiverheid (COA op aanvraag) \u00b7 Discrete temperatuurstabiele verpakking \u00b7 Wereldwijde peptidekoerier \u00b7 1.400+ geverifieerd klantbeoordelingen<\/a><\/div>\n

\ud83d\udce6 Elke bestelling is gedekt door onze Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Specificatie<\/th>\nDetail<\/th>\n<\/tr>\n<\/thead>\n
CAS-nummer<\/strong><\/td>\n307297-39-8<\/td>\n<\/tr>\n
Molecuulformule<\/strong><\/td>\nC14<\/sub>H22<\/sub>N4<\/sub>O9<\/sub><\/td>\n<\/tr>\n
Moleculair gewicht<\/strong><\/td>\n390.35 Da<\/td>\n<\/tr>\n
Sequentie<\/strong><\/td>\nAla-Glu-Asp-Gly (AEDG)<\/td>\n<\/tr>\n
Form<\/strong><\/td>\nLyofiliseerd poeder (of zoals geleverd)<\/td>\n<\/tr>\n
Zuiverheid<\/strong><\/td>\n\u226599% (HPLC geverifieerd, COA op aanvraag)<\/td>\n<\/tr>\n
Opslag<\/strong><\/td>\nLyofiliseerd: 2\u20138 \u00b0C (koelkast) voor werkvoorraad; \u221220 \u00b0C voor langdurige opslag van ongeopende flesjes. Gereconstitueerd: 2\u20138 \u00b0C, gebruik binnen ~30 dagen. Bescherm tegen licht. Vries de gereconstitueerde oplossing niet in en ontdooi deze niet.<\/td>\n<\/tr>\n
Oplosbaarheid<\/strong><\/td>\nBacteriostatisch water (aanbevolen) of steriel water voor kortere gebruiksperioden<\/td>\n<\/tr>\n
Onderzoeksgebruik<\/strong><\/td>\nAlleen voor laboratoriumonderzoek. Niet voor humaan of veterinair diagnostisch of therapeutisch gebruik.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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What Is Epitalon?<\/h2>\n

Epitalon<\/strong> (also called Epithalon<\/strong> of AEDG peptide<\/strong>) is a synthetic four-amino-acid peptide: L-Ala-L-Glu-L-Asp-Gly. It is a synthetic analog of a natural pineal-gland peptide called epithalamin<\/em>, isolated from bovine pineal extract and characterised by Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology beginning in the 1980s.<\/p>\n

Epitalon is one of the most-studied peptides in the Russian longevity-research programme, with published preclinical and small human-cohort research spanning four decades. The research claims \u2014 telomerase activation, chromatin remodeling, lifespan extension in model organisms, normalization of melatonin rhythms in older research subjects \u2014 are substantial but come from a narrow research group; independent Western replication is limited. Molecular weight approximately 390.4\u00a0Da. Supplied as a high-purity lyophilized powder for reconstitution with bacteriostatic water. Epitalon is uitsluitend voor laboratoriumonderzoek<\/strong>. For deeper mechanism, Khavinson research context, and honest-science summary, see our Epitalon research guide<\/a>.<\/p>\n

Mechanism of Action \u2014 Telomerase, Pineal Signaling, Gene Expression<\/h2>\n

Epitalon’s proposed mechanisms span multiple biological systems. The research is suggestive rather than conclusive on direct mechanism, but three pathways appear consistently in the published literature:<\/p>\n