{"id":70733,"date":"2026-05-12T10:13:05","date_gmt":"2026-05-12T10:13:05","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&p=70733"},"modified":"2026-05-21T07:14:10","modified_gmt":"2026-05-21T07:14:10","slug":"ghrp-6","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/ghrp-6\/","title":{"rendered":"GHRP-6 Acetaat"},"content":{"rendered":"

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Quick Answer \u2014 What is GHRP-6 Acetate?<\/h3>\n

GHRP-6 Acetaat<\/strong> (Growth Hormone Releasing Peptide 6) is a 6-amino-acid synthetic hexapeptide and one of the original growth hormone secretagogues, developed by Bowers and colleagues as the second-generation member of the GHRP series. It acts on the growth hormone secretagogue receptor (GHS-R1a) \u2014 the same receptor as endogenous ghrelin \u2014 producing pulsatile GH release alongside appetite stimulation. Supplied in 5\u00a0mg and 10\u00a0mg lyophilized vials for laboratory research use only.<\/p>\n<\/div>\n

Wat u krijgt bij MedsBase:<\/strong> Onderzoekskwaliteit lyofiliseerde peptiden \u00b7 HPLC \u226599% zuiverheid (COA op aanvraag) \u00b7 Discrete temperatuurstabiele verpakking \u00b7 Wereldwijde peptidekoerier \u00b7 1.400+ geverifieerd klantbeoordelingen<\/a><\/div>\n

\ud83d\udce6 Elke bestelling is gedekt door onze Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Specificatie<\/th>\nDetail<\/th>\n<\/tr>\n<\/thead>\n
CAS-nummer<\/strong><\/td>\n87616-84-0 (GHRP-6 free base); supplied as the acetate salt form<\/td>\n<\/tr>\n
Molecuulformule<\/strong><\/td>\nC46<\/sub>H56<\/sub>N12<\/sub>O6<\/sub> (free base; acetate salt adds CH3<\/sub>COOH counterion)<\/td>\n<\/tr>\n
Moleculair gewicht<\/strong><\/td>\n873.02 Da (free base)<\/td>\n<\/tr>\n
Sequentie<\/strong><\/td>\nHis-D-Trp-Ala-Trp-D-Phe-Lys-NH2<\/sub> (HwAWfK-NH2<\/sub>, 6 amino acids; contains D-Trp at position 2 and D-Phe at position 5 for proteolytic stability; C-terminally amidated)<\/td>\n<\/tr>\n
Form<\/strong><\/td>\nLyophilized acetate salt (white to off-white powder)<\/td>\n<\/tr>\n
Zuiverheid<\/strong><\/td>\n\u226599% (HPLC geverifieerd, COA op aanvraag)<\/td>\n<\/tr>\n
Opslag<\/strong><\/td>\nLyofiliseerd: 2\u20138 \u00b0C (koelkast) voor werkvoorraad; \u221220 \u00b0C voor langdurige opslag van ongeopende flesjes. Gereconstitueerd: 2\u20138 \u00b0C, gebruik binnen ~30 dagen. Bescherm tegen licht. Vries de gereconstitueerde oplossing niet in en ontdooi deze niet.<\/td>\n<\/tr>\n
Oplosbaarheid<\/strong><\/td>\nBacteriostatisch water (aanbevolen) of steriel water voor kortere gebruiksperioden<\/td>\n<\/tr>\n
Onderzoeksgebruik<\/strong><\/td>\nAlleen voor laboratoriumonderzoek. Niet voor humaan of veterinair diagnostisch of therapeutisch gebruik.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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What Is GHRP-6 Acetate?<\/h2>\n

GHRP-6<\/strong> (Growth Hormone Releasing Peptide 6) is a 6-amino-acid synthetic hexapeptide and one of the canonical members of the growth hormone secretagogue (GHS) peptide class. It was developed by Cyril Y. Bowers and colleagues at Tulane University as part of a structure-activity relationship programme designed to identify small peptides capable of stimulating pulsatile growth hormone release from the anterior pituitary \u2014 work that ultimately led to the discovery of the growth hormone secretagogue receptor and, indirectly, to the identification of endogenous ghrelin as its natural ligand in 1999 by Kojima et al. (Nature). The acetate counterion is used in research-grade lyophilization because it improves long-term peptide stability and aqueous solubility without altering pharmacology.<\/p>\n

The well-characterised sequence is HwAWfK-NH2<\/sub> (where lowercase letters denote D-amino acid residues), molecular weight 873.02\u00a0Da, empirical formula C46<\/sub>H56<\/sub>N12<\/sub>O6<\/sub>. The two D-amino-acid substitutions (D-Trp at position 2 and D-Phe at position 5) confer resistance to endogenous proteases and extend the in-vivo half-life relative to all-L analogs. The C-terminus is amidated, which is essential for receptor activity. GHRP-6 is niet goedgekeurd<\/strong> by the FDA, EMA, MHRA, or any other major regulator for human therapeutic use. The research-grade GHRP-6 acetate sold here is supplied uitsluitend voor laboratoriumonderzoek<\/strong> and is not intended for human or veterinary administration. For the newer-generation receptor-selective analog without cortisol\/prolactin signalling, see our Ipamorelin<\/a> product page.<\/p>\n

Mechanism of Action \u2014 GHS-R1a Receptor Agonism and the GH Pulse<\/h2>\n

What makes GHRP-6 mechanistically distinctive among growth-axis research peptides is its selective action on the growth hormone secretagogue receptor<\/strong> \u2014 the same receptor activated by endogenous ghrelin \u2014 rather than the GHRH receptor used by sermorelin and CJC-1295. The downstream effect is a pulsatile rather than tonic pattern of GH release in published research:<\/p>\n