{"id":70740,"date":"2026-05-12T10:25:30","date_gmt":"2026-05-12T10:25:30","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&p=70740"},"modified":"2026-05-21T07:14:10","modified_gmt":"2026-05-21T07:14:10","slug":"ghrp-2","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/ghrp-2\/","title":{"rendered":"GHRP-2 Acetaat"},"content":{"rendered":"

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Quick Answer \u2014 What is GHRP-2 Acetate?<\/h3>\n

GHRP-2 Acetaat<\/strong> (also called Pralmorelin or KP-102) is a 6-amino-acid synthetic hexapeptide growth hormone secretagogue and the most potent first-generation member of the GHRP series on a per-mg basis. It acts on the growth hormone secretagogue receptor (GHS-R1a) \u2014 the same receptor as endogenous ghrelin and as GHRP-6<\/a> \u2014 producing pulsatile GH release with a smaller appetite signal than GHRP-6 but a similar cortisol\/prolactin profile. Supplied in 5\u00a0mg and 10\u00a0mg lyophilized vials for laboratory research use only.<\/p>\n<\/div>\n

Wat u krijgt bij MedsBase:<\/strong> Onderzoekskwaliteit lyofiliseerde peptiden \u00b7 HPLC \u226599% zuiverheid (COA op aanvraag) \u00b7 Discrete temperatuurstabiele verpakking \u00b7 Wereldwijde peptidekoerier \u00b7 1.400+ geverifieerd klantbeoordelingen<\/a><\/div>\n

\ud83d\udce6 Elke bestelling is gedekt door onze Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Specificatie<\/th>\nDetail<\/th>\n<\/tr>\n<\/thead>\n
CAS-nummer<\/strong><\/td>\n158861-67-7 (GHRP-2 free base); supplied as the acetate salt form<\/td>\n<\/tr>\n
Molecuulformule<\/strong><\/td>\nC45<\/sub>H55<\/sub>N9<\/sub>O6<\/sub> (free base; acetate salt adds CH3<\/sub>COOH counterion)<\/td>\n<\/tr>\n
Moleculair gewicht<\/strong><\/td>\n817.97 Da (free base)<\/td>\n<\/tr>\n
Sequentie<\/strong><\/td>\nD-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2<\/sub> (6 amino acids; contains D-Ala at position 1, D-2-naphthylalanine at position 2, and D-Phe at position 5 for proteolytic stability; C-terminally amidated). Also known as Pralmorelin \/ KP-102.<\/td>\n<\/tr>\n
Form<\/strong><\/td>\nLyophilized acetate salt (white to off-white powder)<\/td>\n<\/tr>\n
Zuiverheid<\/strong><\/td>\n\u226599% (HPLC geverifieerd, COA op aanvraag)<\/td>\n<\/tr>\n
Opslag<\/strong><\/td>\nLyofiliseerd: 2\u20138 \u00b0C (koelkast) voor werkvoorraad; \u221220 \u00b0C voor langdurige opslag van ongeopende flesjes. Gereconstitueerd: 2\u20138 \u00b0C, gebruik binnen ~30 dagen. Bescherm tegen licht. Vries de gereconstitueerde oplossing niet in en ontdooi deze niet.<\/td>\n<\/tr>\n
Oplosbaarheid<\/strong><\/td>\nBacteriostatisch water (aanbevolen) of steriel water voor kortere gebruiksperioden<\/td>\n<\/tr>\n
Onderzoeksgebruik<\/strong><\/td>\nAlleen voor laboratoriumonderzoek. Niet voor humaan of veterinair diagnostisch of therapeutisch gebruik.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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What Is GHRP-2 Acetate?<\/h2>\n

GHRP-2<\/strong> (Growth Hormone Releasing Peptide 2), also known as Pralmorelin<\/strong> or by its original developmental code KP-102<\/strong>, is a 6-amino-acid synthetic hexapeptide and one of the canonical first-generation members of the growth hormone secretagogue (GHS) peptide class. It was developed shortly after GHRP-6 in the same Bowers structure-activity-relationship programme at Tulane University, with a focus on increasing per-mg potency relative to the parent compound while preserving the GHS-R1a-selective receptor profile. The acetate counterion is used in research-grade lyophilization because it improves long-term peptide stability and aqueous solubility without altering pharmacology.<\/p>\n

The well-characterised sequence is D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2<\/sub>, molecular weight 817.97\u00a0Da, empirical formula C45<\/sub>H55<\/sub>N9<\/sub>O6<\/sub>. The structural innovation relative to GHRP-6 is the introduction of D-2-naphthylalanine (D-2-Nal) at position 2 in place of D-Trp \u2014 the more lipophilic naphthyl ring increases GHS-R1a affinity and produces approximately 2\u20133-fold greater per-mg GH-releasing potency in published research. The two D-amino-acid substitutions (D-Ala at position 1, D-Phe at position 5) confer protease resistance. Notably, in Japan GHRP-2 (under the name Pralmorelin Hydrochloride \/ GHRP Kaken) was approved as a single-use intravenous diagnostic agent for adult growth hormone deficiency testing \u2014 one of the only GHS peptides to reach any form of clinical approval. GHRP-2 remains niet goedgekeurd<\/strong> by the FDA, EMA, MHRA, or any other Western regulator for therapeutic use. The research-grade GHRP-2 acetate sold here is supplied uitsluitend voor laboratoriumonderzoek<\/strong> and is not intended for human or veterinary administration.<\/p>\n

Mechanism of Action \u2014 GHS-R1a Receptor Agonism with Enhanced Potency<\/h2>\n

What makes GHRP-2 mechanistically distinctive among first-generation growth hormone secretagogues is the combination of high GHS-R1a affinity with a relatively short plasma half-life<\/strong>, producing a sharper and more reproducible GH pulse in published research:<\/p>\n