{"id":70789,"date":"2026-05-12T11:08:40","date_gmt":"2026-05-12T11:08:40","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&p=70789"},"modified":"2026-05-21T07:14:09","modified_gmt":"2026-05-21T07:14:09","slug":"ahk-cu","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/ahk-cu\/","title":{"rendered":"AHK-Cu"},"content":{"rendered":"

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Quick Answer \u2014 What is AHK-Cu?<\/h3>\n

AHK-Cu<\/strong> (Alanyl-Histidyl-Lysine Copper(II) complex) is a synthetic copper-binding tripeptide and the sister molecule to GHK-Cu<\/a>. While GHK-Cu is the canonical skin and wound-healing copper peptide, AHK-Cu’s research signal is concentrated in hair follicle biology<\/strong> \u2014 published preclinical work documents stimulation of dermal papilla cells, follicular enlargement, increased follicular vascularization, and prolongation of the anagen growth phase. Supplied in 20\u00a0mg and 50\u00a0mg lyophilized vials for laboratory research use only.<\/p>\n<\/div>\n

Wat u krijgt bij MedsBase:<\/strong> Onderzoekskwaliteit lyofiliseerde peptiden \u00b7 HPLC \u226599% zuiverheid (COA op aanvraag) \u00b7 Discrete temperatuurstabiele verpakking \u00b7 Wereldwijde peptidekoerier \u00b7 1.400+ geverifieerd klantbeoordelingen<\/a><\/div>\n

\ud83d\udce6 Elke bestelling is gedekt door onze Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Specificatie<\/th>\nDetail<\/th>\n<\/tr>\n<\/thead>\n
CAS-nummer<\/strong><\/td>\n110374-12-4 (AHK-Cu); 71567-06-1 (AHK free peptide)<\/td>\n<\/tr>\n
Molecuulformule<\/strong><\/td>\nC15<\/sub>H25<\/sub>CuN6<\/sub>O4<\/sub> (1:1 copper complex)<\/td>\n<\/tr>\n
Moleculair gewicht<\/strong><\/td>\n~417 Da (copper complex)<\/td>\n<\/tr>\n
Sequentie<\/strong><\/td>\nAla-His-Lys (AHK, 3 amino acids) coordinated to a single Cu2+<\/sup> ion via the imidazole nitrogen of His, the amino terminus of Ala, and the deprotonated peptide nitrogen between Ala and His<\/td>\n<\/tr>\n
Form<\/strong><\/td>\nLyophilized copper-peptide complex (blue to blue-violet powder; colour comes from the d-d transitions of bound Cu2+<\/sup>)<\/td>\n<\/tr>\n
Zuiverheid<\/strong><\/td>\n\u226599% (HPLC geverifieerd, COA op aanvraag)<\/td>\n<\/tr>\n
Opslag<\/strong><\/td>\nLyofiliseerd: 2\u20138 \u00b0C (koelkast) voor werkvoorraad; \u221220 \u00b0C voor langdurige opslag van ongeopende flesjes. Gereconstitueerd: 2\u20138 \u00b0C, gebruik binnen ~30 dagen. Bescherm tegen licht. Vries de gereconstitueerde oplossing niet in en ontdooi deze niet.<\/td>\n<\/tr>\n
Oplosbaarheid<\/strong><\/td>\nBacteriostatic water (recommended) or sterile water for shorter use windows. Soluble in water; the dissolved solution retains the characteristic blue colour of the bound Cu2+<\/sup>.<\/td>\n<\/tr>\n
Onderzoeksgebruik<\/strong><\/td>\nAlleen voor laboratoriumonderzoek. Niet voor humaan of veterinair diagnostisch of therapeutisch gebruik.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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What Is AHK-Cu?<\/h2>\n

AHK-Cu<\/strong> (Alanyl-Histidyl-Lysine Copper(II) complex) is a synthetic copper-binding tripeptide composed of the three amino acids Ala, His, and Lys, coordinated to a single Cu2+<\/sup> ion. It is the sister molecule of the more extensively studied GHK-Cu<\/a> \u2014 both belong to the “copper peptide” class, both share the same Cu-coordination architecture using a histidine residue, and both are studied in dermatological research contexts. Where they diverge is in primary research signal: GHK-Cu is the canonical research peptide for skin remodelling, wound healing, and connective-tissue repair, while AHK-Cu’s most-cited research applications are in hair follicle biology<\/strong>.<\/p>\n

The well-characterised molecular composition is C15<\/sub>H25<\/sub>CuN6<\/sub>O4<\/sub>, molecular weight approximately 417\u00a0Da. The Cu2+<\/sup> ion coordinates with the tripeptide via the imidazole nitrogen of histidine, the amino terminus of alanine, and the deprotonated peptide nitrogen between Ala and His \u2014 the same square-planar coordination geometry as in GHK-Cu. The bound copper gives both compounds their characteristic blue-to-violet colour in solid and dissolved form \u2014 researchers reconstituting AHK-Cu should expect a visibly blue working solution.<\/p>\n

AHK-Cu is supplied as a high-purity lyophilized copper-peptide complex for reconstitution with bacteriostatic water. The compound is niet goedgekeurd<\/strong> by the FDA, EMA, MHRA, or any other major regulator for human therapeutic use. The research-grade AHK-Cu sold here is supplied uitsluitend voor laboratoriumonderzoek<\/strong> and is not intended for human or veterinary administration. For the sister skin-research copper peptide, see our GHK-Cu<\/a> product page.<\/p>\n

Mechanism of Action \u2014 Copper Delivery to Hair Follicle Papilla Cells<\/h2>\n

What makes AHK-Cu mechanistically distinctive among copper peptides is its preferential signalling at dermal papilla cells<\/strong> in the hair follicle \u2014 the mesenchymal cells at the base of each follicle that regulate hair-shaft production and cycle through the growth (anagen), regression (catagen), and rest (telogen) phases. Published research has documented three principal mechanisms:<\/p>\n