{"id":71477,"date":"2026-05-20T10:00:00","date_gmt":"2026-05-20T10:00:00","guid":{"rendered":"https:\/\/medsbase.com\/hexarelin-acetate\/"},"modified":"2026-05-21T07:14:09","modified_gmt":"2026-05-21T07:14:09","slug":"hexarelin-acetate","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/hexarelin-acetate\/","title":{"rendered":"Hexarelin Acetaat (Examorelin)"},"content":{"rendered":"

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Quick Answer \u2014 What is Hexarelin Acetate?<\/h3>\n

Hexarelin Acetate<\/strong> (also called Examorelin<\/strong>) is a synthetic 6-amino-acid growth hormone secretagogue (GHS)<\/strong>: His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2<\/sub>, with the bioactive acetate salt counterion. CAS 140703-51-1 (free peptide) \/ 171263-26-6 (acetate salt). MW 887.04 free \/ 947.07 g\/mol as acetate. The most potent ghrelin mimetic in the GHRP-2 \/ GHRP-6 \/ Ipamorelin family \u2014 strongly activates GHSR-1a on pituitary somatotrophs and on cardiomyocytes (the latter via CD36 receptor for cardioprotective effects independent of GH release). Drives strong GH pulsatile release without acute hunger increase, but with documented cortisol and prolactin elevation at higher doses. For laboratory research use only. Synthetic peptide \u2014 not natural ghrelin.<\/em><\/p>\n<\/div>\n

Wat u krijgt bij MedsBase:<\/strong> Lyophilized \u226599% HPLC-verified Hexarelin Acetate \u00b7 COA available on request \u00b7 Discreet temperature-stable packaging \u00b7 Worldwide research-supply courier \u00b7 1,400+ verified klantbeoordelingen<\/a><\/div>\n

\ud83d\udce6 Elke bestelling is gedekt door onze Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Specificatie<\/th>\nDetail<\/th>\n<\/tr>\n<\/thead>\n
Compound Class<\/strong><\/td>\nSynthetic 6-aa peptide growth hormone secretagogue (GHRP family); ghrelin mimetic; acetate salt<\/td>\n<\/tr>\n
Chemical Name<\/strong><\/td>\nHexarelin Acetate (synonyms: Examorelin, EP-23905, MF6003)<\/td>\n<\/tr>\n
CAS-nummer<\/strong><\/td>\n140703-51-1 (free peptide); 171263-26-6 (acetate salt)<\/td>\n<\/tr>\n
Sequentie<\/strong><\/td>\nL-His-D-2-methyl-Trp-L-Ala-L-Trp-D-Phe-L-Lys-NH2<\/sub> (6 amino acids; D-2-Me-Trp at position 2 and D-Phe at position 5 confer proteolytic stability and receptor selectivity; C-terminal amide)<\/td>\n<\/tr>\n
Molecular Formula \/ MW<\/strong><\/td>\nC47<\/sub>H58<\/sub>N12<\/sub>O6<\/sub> (free peptide, MW 887.04 g\/mol); + C2<\/sub>H4<\/sub>O2<\/sub> acetate counterion (acetate salt, MW 947.07 g\/mol)<\/td>\n<\/tr>\n
Werkingsmechanisme<\/strong><\/td>\nDual-receptor pharmacology. (1) Primary: agonist at GHSR-1a<\/strong> (growth-hormone-secretagogue receptor type 1a, the ghrelin receptor) on pituitary somatotrophs \u2014 drives strong pulsatile GH release via Gq-PLC-IP3<\/sub>-Ca2+<\/sup> signalling; also engages GHSR on arcuate-nucleus neurons. (2) Secondary: binds CD36<\/strong> (a scavenger receptor) on cardiomyocytes, vascular endothelium, and macrophages \u2014 produces cardioprotective effects in ischaemia-reperfusion models independent<\/em> of GH release. The dual mechanism is unique to Hexarelin among the GHRP family.<\/td>\n<\/tr>\n
Potency vs Family<\/strong><\/td>\nMost potent GH-releasing peptide in the GHRP-2 \/ GHRP-6 \/ Hexarelin \/ Ipamorelin family on a per-mg basis \u2014 but with corresponding cortisol and prolactin elevation at higher doses (in contrast to Ipamorelin<\/a>, which produces clean GH-only release).<\/td>\n<\/tr>\n
Form<\/strong><\/td>\nLyophilized white-to-off-white powder; single-use research vials<\/td>\n<\/tr>\n
Zuiverheid<\/strong><\/td>\n\u226599% (HPLC geverifieerd, COA op aanvraag)<\/td>\n<\/tr>\n
Opslag<\/strong><\/td>\nLyophilized: 2\u20138 \u00b0C short-term; \u221220 \u00b0C long-term (\u226536 months). Reconstituted: 2\u20138 \u00b0C, use within 30 days. Avoid repeated freeze-thaw.<\/td>\n<\/tr>\n
Onderzoeksgebruik<\/strong><\/td>\nFor laboratory research use only. Not for human or veterinary diagnostic or therapeutic use. Hexarelin \/ Examorelin is on the WADA Prohibited List (class S2, Peptide Hormones and Growth Factors) and is prohibited at all times in athletic contexts.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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Mechanism of Action \u2014 Dual GHSR-1a + CD36 Pharmacology<\/h2>\n

Hexarelin is unique among the GHRP family in having well-documented activity at two mechanistically distinct receptors:<\/p>\n