{"id":71497,"date":"2026-05-20T10:20:00","date_gmt":"2026-05-20T10:20:00","guid":{"rendered":"https:\/\/medsbase.com\/thymalin\/"},"modified":"2026-05-21T07:14:09","modified_gmt":"2026-05-21T07:14:09","slug":"thymalin","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nl\/thymalin\/","title":{"rendered":"Thymalin (Khavinson Thymic Polypeptide Bioregulator)"},"content":{"rendered":"

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Quick Answer \u2014 What is Thymalin?<\/h3>\n

Thymalin<\/strong> is a polypeptide preparation extracted from calf or porcine thymus tissue, developed by Khavinson<\/strong> and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology beginning in the 1970s. Unlike single-peptide research compounds, Thymalin is a multi-component peptide complex<\/strong> (typical MW range 1\u201310 kDa across the mixture) consisting of short oligopeptide bioregulators that originate in thymic stromal cells. The most cited active components are tetrapeptide EW (Glu-Trp) and other Khavinson-class short peptide bioregulators. Thymalin is used in published Russian and Eastern European research as a thymus-axis immune-modulator that promotes T-cell maturation, restores age-related thymic involution markers, and modulates neuroendocrine-immune crosstalk. For laboratory research use only. Polypeptide bioregulator preparation \u2014 not a single-sequence peptide.<\/em><\/p>\n<\/div>\n

Wat u krijgt bij MedsBase:<\/strong> Lyophilized \u226599% HPLC-verified Thymalin preparation \u00b7 COA available on request \u00b7 Discreet temperature-stable packaging \u00b7 Worldwide research-supply courier \u00b7 1,400+ verified klantbeoordelingen<\/a><\/div>\n

\ud83d\udce6 Elke bestelling is gedekt door onze Reshipment Assurance Policy<\/strong><\/a> \u2014 als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Specificatie<\/th>\nDetail<\/th>\n<\/tr>\n<\/thead>\n
Compound Class<\/strong><\/td>\nPolypeptide bioregulator preparation (multi-component thymic peptide mixture); Khavinson-class peptide bioregulator<\/td>\n<\/tr>\n
Source<\/strong><\/td>\nTissue-extracted from calf or porcine thymus; purified by acid extraction + chromatographic fractionation<\/td>\n<\/tr>\n
CAS-nummer<\/strong><\/td>\nMulti-component preparation \u2014 no single canonical CAS; identification by HPLC fingerprint and bioactivity assay<\/td>\n<\/tr>\n
Molecuulformule<\/strong><\/td>\nMulti-component thymic polypeptide bioregulator (Khavinson preparation) \u2014 heterogeneous low-molecular-weight peptide pool from calf thymus ultrafiltrate, < 10 kDa. No single molecular formula due to multi-peptide composition; activity assigned to the short-peptide fraction.<\/td>\n<\/tr>\n
Active Components<\/strong><\/td>\nMixture of short oligopeptides (di- through hexapeptides predominantly), MW range ~200\u201310,000 Da. Best-characterised components include thymic dipeptide EW (Glu-Trp) and other Khavinson short-peptide bioregulators.<\/td>\n<\/tr>\n
Werkingsmechanisme<\/strong><\/td>\nMulti-component thymus-axis immune modulation. Published research attributes effects to: (1) promotion of T-cell precursor maturation in thymic cortex and medulla; (2) restoration of age-related thymic involution markers (improved TREC count, increased thymic-output naive T-cell production); (3) modulation of cytokine balance (IL-2, IFN-\u03b3 upregulation in lymphocyte cultures); (4) crosstalk with hypothalamic-pituitary axis via the Khavinson-peptide bioregulator network.<\/td>\n<\/tr>\n
Form \/ Purity<\/strong><\/td>\nLyophilized white-to-pale-yellow amorphous powder; \u226599% HPLC purity (multi-component preparation; HPLC profile-fingerprint COA available)<\/td>\n<\/tr>\n
Opslag<\/strong><\/td>\nLyophilized: 2\u20138 \u00b0C short-term, \u221220 \u00b0C long-term. Reconstituted: 2\u20138 \u00b0C, use within 30 days. Avoid freeze-thaw.<\/td>\n<\/tr>\n
Onderzoeksgebruik<\/strong><\/td>\nFor laboratory research use only. Not for human or veterinary diagnostic or therapeutic use. Thymalin has clinical-use approval in Russia and several CIS countries but is not approved by FDA \/ EMA \/ MHRA. Not on the WADA Prohibited List.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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Mechanism of Action \u2014 Thymic-Axis Bioregulator<\/h2>\n

Thymalin is the canonical Khavinson-class peptide bioregulator<\/strong> derived from thymic tissue. The Khavinson bioregulator concept (developed at the St. Petersburg Institute of Bioregulation and Gerontology from the 1970s) posits that tissue-specific short peptides act as inter-organ signalling molecules that maintain age-appropriate tissue function \u2014 and that age-related decline reflects loss of these peptide bioregulator signals from the source tissue. Thymalin is the original member of this class and is used in published Russian research as the canonical thymus-axis bioregulator.<\/p>\n

Mechanism of action across published research:<\/p>\n