{"id":3260,"count":141,"description":"The MedsBase Heart &amp; Blood Pressure parent catalogue groups all cardiovascular medications \u2014 antihypertensives across the major drug classes, anti-anginal nitrates, anti-arrhythmics, heart-failure agents, and pulmonary arterial hypertension specialty drugs. The detailed clinical breakdown by drug class with full molecule and brand listing is in our <a href=\"https:\/\/medsbase.com\/nl\/high-blood-pressure-medication\/\">Medicatie tegen hoge bloeddruk<\/a> sub-category \u2014 please browse there for selection guidance and dosing context. All products are supplied by <strong>WHO-GMP gecertificeerde fabrikanten<\/strong>.\n\n<strong>Drug-class summary.<\/strong> ARBs (angiotensin-receptor blockers \u2014 losartan, valsartan, telmisartan, olmesartan, candesartan, irbesartan), ACE inhibitors (ramipril, lisinopril, enalapril, perindopril, captopril), beta-blockers (atenolol, metoprolol, bisoprolol, carvedilol, nebivolol, propranolol, labetalol, esmolol), calcium-channel blockers (amlodipine, nifedipine, felodipine, diltiazem, verapamil), diuretics (hydrochlorothiazide, indapamide, furosemide, torasemide, bumetanide, spironolactone, eplerenone, amiloride), alpha-blockers (prazosin, terazosin, doxazosin), centrally-acting agents (clonidine, alpha-methyldopa), nitrates (isosorbide mononitrate, isosorbide dinitrate, nitroglycerin sublingual \/ spray \/ patch), and specialty agents (ivabradine for HF, ambrisentan and riociguat for PAH, minoxidil for resistant HTN, sacubitril-valsartan for HFrEF).\n\n<strong>Anti-thrombotic adjuncts.<\/strong> Aspirin 75\u2013325 mg (Ecosprin), clopidogrel (Clodict, Plavix), warfarin (Warf, Waf-5), DOACs (Xarelto rivaroxaban, Eliquis apixaban) for primary and secondary cardiovascular prevention. See our <a href=\"https:\/\/medsbase.com\/nl\/anti-coagulants\/\">Antistollingsmiddelen<\/a> category.\n\n<strong>Lipid-lowering co-treatment.<\/strong> Statins (atorvastatin, rosuvastatin, simvastatin, pitavastatin), fenofibrate, ezetimibe, and cholestyramine for cardiovascular risk reduction \u2014 see our <a href=\"https:\/\/medsbase.com\/nl\/high-cholesterol-treatments\/\">Behandelingen voor hoog cholesterol<\/a> category.\n\n<strong>Hoe te kiezen.<\/strong> Modern ESC \/ NICE 2023 first-line for hypertension: ARB or ACE inhibitor (under 55, non-Black) OR calcium-channel blocker (over 55 or Black). Step-up to dual therapy (ARB\/ACEi + CCB), then triple (add thiazide \/ thiazide-like diuretic), then quadruple (add spironolactone if K+ &lt; 4.5). Target BP &lt; 140\/90 (130\/80 in diabetes \/ CKD \/ high CVD risk). Heart-failure with reduced ejection fraction (HFrEF) \u2014 sacubitril-valsartan (or ARB\/ACEi) + beta-blocker + MRA + SGLT-2 inhibitor (the four pillars). Coronary artery disease \u2014 beta-blocker + statin + antiplatelet + ACEi\/ARB if HTN or LV dysfunction.\n\n<strong>Belangrijk.<\/strong> Cardiovascular medications work best when taken consistently \u2014 please keep your primary-care team and cardiologist informed. Sudden discontinuation of beta-blockers or clonidine causes rebound hypertension \/ angina \/ arrhythmia \u2014 always taper. ACEi \/ ARB combinations are no longer recommended (ON-TARGET trial). Pregnancy: ACE inhibitors and ARBs are absolutely contraindicated; methyldopa, labetalol, nifedipine are first-line for pregnancy hypertension. Severe symptomatic hypotension, syncope, oedema, breathlessness, palpitations, or chest pain warrants prompt medical assessment.\n\nAll MedsBase Heart &amp; Blood Pressure products ship from <strong>WHO-GMP gecertificeerde fabrikanten<\/strong> met discrete verpakking en vallen onder onze <a href=\"https:\/\/medsbase.com\/nl\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance Policy<\/a>.","link":"https:\/\/medsbase.com\/nl\/heart-blood-pressure\/","name":"Hart &amp; Bloeddruk","slug":"heart-blood-pressure","taxonomy":"product_cat","parent":3223,"meta":[],"menu_order":0,"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat\/3260","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat"}],"about":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/taxonomies\/product_cat"}],"up":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product_cat\/3223"}],"wp:post_type":[{"href":"https:\/\/medsbase.com\/nl\/wp-json\/wp\/v2\/product?product_cat=3260"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}