<\/p>\n
Pic\u0103turile oculare Combigan combin\u0103 brimonidina 0,2% (agonist alfa-2) cu timolol 0,5% (beta-blocant) \u00eentr-o singur\u0103 sticl\u0103 pentru glaucom avansat. Se administreaz\u0103 de dou\u0103 ori pe zi. Evita\u021bi \u00een caz de astm, BPOC sever\u0103, bradicardie, bloc AV \u0219i copii sub 2 ani.<\/p>\n<\/div>\n
\ud83d\udce6 Fiecare comand\u0103 este acoperit\u0103 de politica noastr\u0103 de Politica noastr\u0103 de Reexpediere Garantat\u0103<\/strong><\/a> \u2014 dac\u0103 coletul dumneavoastr\u0103 nu sose\u0219te \u00een 20 de zile lucr\u0103toare, \u00eel relivr\u0103m.<\/p>\n Pic\u0103turile oculare Combigan provin de la un produc\u0103tor certificat WHO-GMP \u0219i sunt expediate \u00een \u00eentreaga lume \u00een ambalaje discrete \u0219i simple. Fiecare comand\u0103 este acoperit\u0103 de Politica noastr\u0103 de Reexpediere Garantat\u0103<\/a> \u2014 dac\u0103 nu a sosit \u00een 20 de zile lucr\u0103toare, expediem din nou f\u0103r\u0103 costuri suplimentare. Sus\u021binut de peste 1.400 de recenzii verificate.<\/p>\n Combigan Eye Drop este un colir cu doz\u0103 fix\u0103 fabricat de Allergan, care con\u021bine tartrat de brimonidin\u0103 0,2% \u0219i maleat de timolol 0,5% \u00eentr-un flacon de 5 mL. Cele dou\u0103 ingrediente reduc produc\u021bia de umoare apoas\u0103 prin mecanisme complementare \u2014 agonism alfa-2 \u0219i blocare beta-adrenergic\u0103 \u2014 pentru o reducere aditiv\u0103 a PIO de ~25\u201328% la administrarea de dou\u0103 ori pe zi.<\/p>\n Brimonidina<\/strong> activeaz\u0103 receptorii alfa-2 la nivelul epiteliului ciliar, sc\u0103z\u00e2nd cAMP \u0219i secre\u021bia de umoare apoas\u0103, cresc\u00e2nd totodat\u0103 debitul uveoscleral. Timolol<\/strong> blocheaz\u0103 receptorii beta-1\/beta-2 la acela\u0219i epiteliu, reduc\u00e2nd \u0219i mai mult produc\u021bia de umoare apoas\u0103. Combina\u021bia este mai poten\u021b\u0103 dec\u00e2t fiecare monoterapie.<\/p>\n O pic\u0103tur\u0103 \u00een ochiul (ochii) afectat de dou\u0103 ori pe zi, ideal la interval de 12 ore. A\u0219tepta\u021bi 5 minute dac\u0103 utiliza\u021bi alte coliruri. Practica\u021bi ocluzia punctal\u0103 timp de 1\u20132 minute dup\u0103 fiecare pic\u0103tur\u0103. Scoate\u021bi lentilele de contact; reintroduce\u021bi-le dup\u0103 15 minute.<\/p>\n Local:<\/strong> hiperemie conjunctival\u0103, conjunctivit\u0103 alergic\u0103 (cu debut tardiv, caracteristic\u0103 brimonidinei), \u00een\u021bep\u0103tur\u0103, vedere \u00eence\u021bo\u0219at\u0103, prurit ocular.<\/p>\n Sistemic:<\/strong> gur\u0103 uscat\u0103, oboseal\u0103, somnolen\u021b\u0103, hipotensiune, bradicardie, bronhospasm la pacien\u021bii cu c\u0103i respiratorii reactive.<\/p>\n P\u0103stra\u021bi la 15\u201325\u00b0C. Arunca\u021bi dup\u0103 28 de zile de la prima deschidere.<\/p>\n De dou\u0103 ori pe zi, ideal la interval de 12 ore.<\/p>\n Brimonidina \u0219i timololul reduc ambele produc\u021bia de umoare apoas\u0103, dar prin mecanisme diferite. Combina\u021bia este moderat aditiv\u0103 (mai mult dec\u00e2t fiecare separat) \u0219i \u00eenlocuie\u0219te dou\u0103 flacoane separate.<\/p>\n Nu \u2014 componenta de timolol este contraindicat\u0103. Trece\u021bi la o op\u021biune f\u0103r\u0103 beta-blocant.<\/p>\n Ap\u0103sa\u021bi col\u021bul interior al ochiului timp de 1\u20132 minute dup\u0103 instilare. Acest lucru blocheaz\u0103 drenajul lacrimal \u0219i reduce absorb\u021bia sistemic\u0103 a ambelor ingrediente cu ~70%.<\/p>\n Brimonidina traverseaz\u0103 cu u\u0219urin\u021b\u0103 bariera hemato-encefalic\u0103 \u0219i poate provoca apnee, bradicardie \u0219i hipotensiune care pun via\u021ba \u00een pericol la copiii sub 2 ani. Utilizarea este contraindicat\u0103 \u00een aceast\u0103 grup\u0103 de v\u00e2rst\u0103.<\/p>\n Da \u2014 brimonidina are o caracteristic\u0103 conjunctivit\u0103 alergic\u0103 cu debut tardiv (dup\u0103 6\u201318 luni). Ro\u0219ea\u021ba \u0219i m\u00e2nc\u0103rimea ochilor dup\u0103 luni de utilizare f\u0103r\u0103 probleme este un model tipic.<\/p>\n Brimonidina poate provoca somnolen\u021b\u0103 sistemic\u0103, gur\u0103 uscat\u0103 \u0219i hipotensiune u\u0219oar\u0103. Ocluzia punctual\u0103 reduce aceste efecte.<\/p>\n Da \u2014 efect aditiv cu prostaglandinele \u0219i inhibitorii de anhidraz\u0103 carbonic\u0103 (CAI). A\u0219tepta\u021bi 5 minute \u00eentre flacoane.<\/p>\n Evita\u021bi \u2014 este posibil\u0103 sedare \u0219i hipotensiune aditiv\u0103. Informa\u021bi medicul care v-a prescris tratamentul.<\/p>\n Lua\u021bi-l c\u00e2t de cur\u00e2nd v\u0103 aminti\u021bi, cu excep\u021bia cazului \u00een care urmeaz\u0103 doza urm\u0103toare.<\/p>\n <\/p>\n Clien\u021bii care vizualizeaz\u0103 acest produs iau \u00een considerare \u0219i aceste alternative din gama noastr\u0103 \u00cengrijirea ochilor<\/a> de:<\/p>\n Informa\u021biile de pe aceast\u0103 pagin\u0103 au scop educa\u021bional \u0219i nu \u00eenlocuiesc sfatul medical al unui oftalmolog sau optometrist calificat. Afec\u021biunile oculare pot amenin\u021ba rapid vederea \u2014 pierderea brusc\u0103 a vederii, durerea intens\u0103 sau trauma reprezint\u0103 urgen\u021be oftalmologice. Consulta\u021bi \u00eentotdeauna un specialist \u00een \u00eengrijirea ochilor \u00eenainte de a \u00eencepe, \u00eentrerupe sau modifica orice tratament.<\/p>","protected":false},"excerpt":{"rendered":" Combigan (brimonidin\u0103 0,2% + timolol 0,5%) \u2014 combina\u021bie fix\u0103 de agonist alfa-2 + beta-blocant. Control al presiunii intraoculare de dou\u0103 ori pe zi pentru glaucom cu unghi deschis. Avertisment privind apnea pediatric\u0103.<\/p>","protected":false},"featured_media":51242,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3343,3342],"product_tag":[3350,3351,3352],"class_list":{"0":"post-51241","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-eye-care","8":"product_cat-general-health","9":"product_tag-brimonidine-tartrate","10":"product_tag-combigan-eye-drop","11":"product_tag-timolol","13":"first","14":"instock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product\/51241","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/comments?post=51241"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/media\/51242"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/media?parent=51241"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product_brand?post=51241"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product_cat?post=51241"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product_tag?post=51241"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}De ce s\u0103 comanzi de la MedsBase<\/h3>\n
Ce este Combigan Eye Drop?<\/h2>\n
Cum func\u021bioneaz\u0103<\/h2>\n
Doza<\/h2>\n
Efecte Secundare<\/h2>\n
Avertismente & Contraindica\u021bii<\/h2>\n
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Depozitare<\/h2>\n
\u00centreb\u0103ri frecvente<\/h2>\n
C\u00e2nd ar trebui s\u0103 folosesc pic\u0103turile oculare Combigan?<\/h3>\n
De ce se combin\u0103 aceste dou\u0103 medicamente?<\/h3>\n
Pot folosi pic\u0103turile oculare Combigan dac\u0103 am astm?<\/h3>\n
Ce este ocluzia punctual\u0103?<\/h3>\n
De ce este brimonidina nesigur\u0103 la copiii mici?<\/h3>\n
Pot s\u0103 m\u0103 a\u0219tept la o reac\u021bie alergic\u0103 \u00eent\u00e2rziat\u0103?<\/h3>\n
O s\u0103 m\u0103 simt obosit(\u0103)?<\/h3>\n
Pot s\u0103 combin pic\u0103turile Combigan cu alte pic\u0103turi pentru glaucom?<\/h3>\n
Ce se \u00eent\u00e2mpl\u0103 dac\u0103 iau un inhibitor MAO?<\/h3>\n
Ce fac dac\u0103 uit o doz\u0103?<\/h3>\n
Alte medicamente pentru \u00eengrijirea ochilor<\/h3>\n
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Declinare de responsabilitate medical\u0103<\/h3>\n