<\/p>\n
Zivast AM<\/strong> este un Comprimat cu doz\u0103 fix\u0103 10\/5 mg<\/strong> combin\u00e2nd atorvastatin<\/strong> (statin\u0103 de \u00eenalt\u0103 intensitate) cu amlodipine<\/strong> (blocant al canalelor de calciu dihidropiridinic de prim\u0103 linie) de la Cadila Healthcare. Combina\u021bia vizeaz\u0103 doi dintre cei trei factori de risc cardiovascular modificabili cei mai importan\u021bi \u00eentr-un singur comprimat \u2014 colesterol LDL crescut \u0219i tensiune arterial\u0103 ridicat\u0103<\/strong>. Combina\u021biile \u00eentr-un singur comprimat \u00eembun\u0103t\u0103\u021besc substan\u021bial adheren\u021ba (analizele subgrupului ASCOT, meta-analizele sugereaz\u0103 o persisten\u021b\u0103 cu 20-30% mai bun\u0103 la FDC fa\u021b\u0103 de componentele separate). Dozaj tipic: un comprimat o dat\u0103 pe zi, \u00een orice moment al zilei. Contraindicat absolut \u00een sarcin\u0103 (componenta statin\u0103), boli hepatice active, hipotensiune sever\u0103. Monitoriza\u021bi lipidele la 4-12 s\u0103pt\u0103m\u00e2ni; teste hepatice + glicemie la baz\u0103 \u0219i anual; TA regulat.<\/p>\n<\/div>\n \ud83d\udce6 Fiecare comand\u0103 este acoperit\u0103 de politica noastr\u0103 de Politica noastr\u0103 de Reexpediere Garantat\u0103<\/strong><\/a> \u2014 dac\u0103 coletul dumneavoastr\u0103 nu sose\u0219te \u00een 20 de zile lucr\u0103toare, \u00eel relivr\u0103m.<\/p>\n Medicamentele noastre generice sunt procurate de la produc\u0103tori certifica\u021bi WHO-GMP \u0219i expediate la nivel mondial \u00een ambalaje discrete \u0219i simple \u2014 f\u0103r\u0103 denumirea medicamentului pe exteriorul coletului. Pl\u0103\u021bile cu cardul sunt procesate printr-un procesor reglementat (descrierile de pe extrasul de cont includ un procesor de pl\u0103\u021bi cu card reglementat \u2014 niciodat\u0103 \u201cMedsBase\u201d sau numele vreunui medicament). Accept\u0103m \u0219i criptomonede \u0219i transferuri bancare SEPA. Fiecare comand\u0103 este sus\u021binut\u0103 de Politica noastr\u0103 de Asigurare pentru Relivrare.<\/p>\n Zivast AM este un comprimat cu doz\u0103 fix\u0103 care con\u021bine atorvastatin + amlodipin\u0103<\/strong> (raport tipic atorvastatin 10 mg + amlodipin\u0103 5 mg pe comprimat) \u00eentr-un singur comprimat. Fabricat de Cadila Healthcare \u0219i furnizat \u00een cutii de 30-90 de comprimate.<\/p>\n Asocierea se bazeaz\u0103 pe studiile ASCOT-BPLA + ASCOT-LLA (2003-2005), care au ar\u0103tat c\u0103 terapia antihipertensiv\u0103 bazat\u0103 pe amlodipin\u0103 plus atorvastatin 10 mg a produs cu 53% mai pu\u021bine evenimente cardiovasculare dec\u00e2t terapia bazat\u0103 pe atenolol plus placebo la 19.000 de pacien\u021bi hipertensivi cu dislipidemie u\u0219oar\u0103 \u2014 un beneficiu remarcabil determinat \u00een mare m\u0103sur\u0103 de strategia combinat\u0103 statin\u0103 + BCC.<\/p>\n Doza standard:<\/strong> un comprimat de 10\/5 mg o dat\u0103 pe zi, la orice or\u0103, cu sau f\u0103r\u0103 m\u00e2ncare.<\/p>\n C\u00e2nd s\u0103 \u00eencepe\u021bi:<\/strong> pacientul tipic este cel cu hipertensiune + dislipidemie sau hipertensiune + risc ASCVD stabilit >7,5%, deja stabilizat pe amlodipin\u0103 + atorvastatin\u0103 \u00een doze corespunz\u0103toare FDC. Alternativ, un pacient nou tratat cu risc CV ridicat unde terapia combinat\u0103 ini\u021bial\u0103 este preferat\u0103 titr\u0103rii monoterapiei (AHA\/ACC 2018).<\/p>\n Titrarea:<\/strong> dac\u0103 TA sau lipidele r\u0103m\u00e2n \u00een afara \u021bintei dup\u0103 4-6 s\u0103pt\u0103m\u00e2ni, substitui\u021bi cu un FDC de putere mai mare (atorvastatin\u0103 20 mg + amlodipin\u0103 5 mg, sau 10\/10 etc.) sau ad\u0103uga\u021bi un al treilea agent (inhibitor ACE\/ARB pentru TA; ezetimib\u0103 pentru LDL).<\/p>\n Monitorizare:<\/strong><\/p>\n Combin\u0103 profilele celor dou\u0103 componente. De obicei mai bine tolerat\u0103 dec\u00e2t dozele maxime de monoterapie ale fiec\u0103rui agent, deoarece FDC utilizeaz\u0103 doze moderate ale ambelor substan\u021be.<\/p>\n Frecvente:<\/strong><\/p>\n Pu\u021bin frecvente, dar grave:<\/strong><\/p>\n P\u0103stra\u021bi Zivast AM sub 25\u00b0C \u00een ambalajul original blister. \u021aine\u021bi departe de copii.<\/p>\n Este o combina\u021bie cu doz\u0103 fix\u0103<\/strong> de obicei utilizat la pacien\u021bi care sunt deja stabili pe amlodipin\u0103 + atorvastatin\u0103 \u00een doze componente corespunz\u0103toare, sau la pacien\u021bi nou-trata\u021bi \u00een care prescriptorul a ales s\u0103 combine ambele clase de la \u00eenceput. Nu este de obicei primul medicament ini\u021biat la un pacient netratat anterior \u2014 este mai degrab\u0103 versiunea \u00eentr-o singur\u0103 pastil\u0103 a unui regim cu dou\u0103 medicamente care s-a dovedit a fi potrivit.<\/p>\n Da \u2014 ad\u0103ugarea unui inhibitor ACE sau a unui ARB este un pas standard de intensificare care, de asemenea, compenseaz\u0103 de obicei edemul de glezn\u0103 legat de amlodipin\u0103. Evita\u021bi ad\u0103ugarea unui alt CCB sau a unui alt statin.<\/p>\n Nu \u2014 atorvastatina are o semivia\u021b\u0103 lung\u0103 \u0219i momentul administr\u0103rii nu conteaz\u0103. Semivia\u021ba de 30-50 de ore a amlodipinei \u00eenseamn\u0103 c\u0103 nivelurile la starea de echilibru sunt constante, indiferent de momentul administr\u0103rii. Alege\u021bi un moment pe care \u00eel ve\u021bi \u021bine minte \u00een mod constant.<\/p>\n Contraindica\u021bie absolut\u0103 \u2014 componenta de statin\u0103 este teratogen\u0103 \u0219i ambele componente trec prin placent\u0103. Trece\u021bi la metildop\u0103, labetalol sau nifedipin\u0103 pentru controlul tensiunii arteriale \u00een sarcin\u0103; \u00eentrerupe\u021bi statina.<\/p>\n Pute\u021bi cump\u0103ra Zivast AM (atorvastatin\u0103 + amlodipin\u0103 10\/5 mg, 30-90 de comprimate) de la MedsBase cu ambalaj discret \u0219i livrare la nivel mondial.<\/p>\n <\/p>\n Zivast AM este combina\u021bia fix\u0103 de atorvastatin 10 mg + amlodipin\u0103 5 mg a lui Cadila \u2014 o combina\u021bie \u00eentr-o singur\u0103 pastil\u0103 care abordeaz\u0103 cei doi factori de risc cardiovascular cel mai frecvent coexisten\u021bi: hipertensiunea \u0219i dislipidemia. ASCOT-BPLA \u0219i ASCOT-LLA (2003-2005) au demonstrat c\u0103 terapia bazat\u0103 pe amlodipin\u0103 + atorvastatin 10 mg a redus evenimentele cardiovasculare cu 53% fa\u021b\u0103 de terapia bazat\u0103 pe atenolol + placebo la 19.000 de pacien\u021bi hipertensivi. Combina\u021biile \u00eentr-o singur\u0103 pastil\u0103 \u00eembun\u0103t\u0103\u021besc substan\u021bial adheren\u021ba fa\u021b\u0103 de prescrip\u021biile separate.<\/p>","protected":false},"featured_media":51982,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3260,3356],"product_tag":[3362,3435,3436],"class_list":{"0":"post-51981","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-heart-blood-pressure","9":"product_cat-high-blood-pressure-medication","10":"product_tag-amlodipine","11":"product_tag-atorvastatin","12":"product_tag-zivast-am","14":"first","15":"outofstock","16":"shipping-taxable","17":"purchasable","18":"product-type-variable","19":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product\/51981","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/comments?post=51981"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/media\/51982"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/media?parent=51981"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product_brand?post=51981"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product_cat?post=51981"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product_tag?post=51981"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}De ce s\u0103 comanzi de la MedsBase<\/h3>\n
Ce este Zivast AM?<\/h2>\n
De ce s\u0103 combini Atorvastatin cu Amlodipin\u0103?<\/h2>\n
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Doza \u0219i titrare<\/h2>\n
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Efecte Secundare<\/h2>\n
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Contraindica\u021bii<\/h2>\n
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Interac\u021biuni medicamentoase<\/h2>\n
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Depozitare<\/h2>\n
\u00centreb\u0103ri frecvente<\/h2>\n
Este Zivast AM o terapie de prim\u0103 linie?<\/h3>\n
Pot lua Zivast AM \u00eempreun\u0103 cu alte medicamente pentru tensiune arterial\u0103?<\/h3>\n
Ar trebui s\u0103 iau Zivast AM noaptea?<\/h3>\n
Ce zice\u021bi despre sarcin\u0103?<\/h3>\n
Unde pot cump\u0103ra Zivast AM online?<\/h3>\n
Medicamente conexe pentru cardiologie \u0219i hipertensiune<\/h2>\n
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