{"id":53634,"date":"2023-09-20T09:49:00","date_gmt":"2023-09-20T09:49:00","guid":{"rendered":"https:\/\/medsname.com\/urotel-xl\/"},"modified":"2026-04-30T10:25:11","modified_gmt":"2026-04-30T10:25:11","slug":"urotel-xl","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ro\/product\/urotel-xl\/","title":{"rendered":"Urotel XL"},"content":{"rendered":"

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R\u0103spuns rapid<\/h3>\n

Urotel XL<\/strong> con\u021bine tartrat de tolterodin\u0103 cu eliberare prelungit\u0103 4 mg ER<\/strong> fabricat de Sun Pharma. Este utilizat pentru simptomele vezicii hiperactive (OAB) \u2014 urgen\u021b\u0103, frecven\u021b\u0103 \u0219i incontinen\u021b\u0103 de urgen\u021b\u0103. Lua\u021bi exact conform indica\u021biilor clinicianului dumneavoastr\u0103 \u2014 nu ajusta\u021bi singur doza.<\/p>\n<\/div>\n

\nCe beneficii ofer\u0103 MedsBase:<\/strong> Produc\u0103tor certificat WHO-GMP \u00b7 Ambalaj discret \u00b7 Livrare la nivel mondial \u00b7 Peste 1.400 de recenzii verificate ale clien\u021bilor<\/a>\n<\/div>\n

\ud83d\udce6 Fiecare comand\u0103 este acoperit\u0103 de politica noastr\u0103 de Politica noastr\u0103 de Reexpediere Garantat\u0103<\/strong><\/a> \u2014 dac\u0103 coletul dumneavoastr\u0103 nu sose\u0219te \u00een 20 de zile lucr\u0103toare, \u00eel relivr\u0103m.<\/p>\n

\ud83d\udd12 Checkout criptat<\/strong> \u00b7 \ud83d\udcb3 Procesor verificat<\/strong> \u00b7 \ud83d\ude9a Livrare worldwide<\/strong> \u00b7 \u2b50 4,9\/5 de la peste 1.400 de clien\u021bi<\/strong><\/div>\n

De ce s\u0103 comanzi de la MedsBase<\/h3>\n

Fiecare lot este procurat de la un produc\u0103tor certificat WHO-GMP<\/strong>. Comenzile sunt expediate \u00een ambalaje simple, f\u0103r\u0103 marc\u0103, de la partenerii no\u0219tri de onorare \u0219i sunt acoperite de Politica noastr\u0103 de Reexpediere Garantat\u0103<\/a>. Am servit 1.400+ clien\u021bi verifica\u021bi<\/strong> cu un rating mediu de 4,9\/5<\/strong> pe mai mult de 600 de medicamente.<\/p>\n

Ce este Urotel XL \u0219i cum func\u021bioneaz\u0103<\/h2>\n

Urotel XL con\u021bine tartrat de tolterodin\u0103<\/strong> \u00eentr-o form\u0103 cu eliberare prelungit\u0103<\/strong> formulare, luat\u0103 o dat\u0103 pe zi. Tolterodina este un antagonist competitiv al receptorilor muscarinici care ac\u021bioneaz\u0103 asupra receptorilor muscarinici vezicali cu un efect func\u021bional u\u0219or mai mare dec\u00e2t asupra receptorilor glandelor salivare, oferind un profil u\u0219or mai bun de usc\u0103ciune a gurii dec\u00e2t oxibutinina (\u00een special \u00een formularea cu eliberare prelungit\u0103).<\/p>\n

Este autorizat\u0103 pentru sindromul vezicii hiperactive cu simptome de urinare frecvent\u0103, urgen\u021b\u0103 \u0219i incontinen\u021b\u0103 de urgen\u021b\u0103<\/strong>. Capsula cu eliberare prelungit\u0103 asigur\u0103 niveluri plasmatice mai uniforme dec\u00e2t comprimatul vechi cu eliberare imediat\u0103 \u0219i reduce efectele secundare tipice (\u00een special usc\u0103ciunea gurii) cu ~30%.<\/p>\n

Doza \u0219i modul de administrare<\/h2>\n\n\n\n\n\n\n\n
Grup de pacien\u021bi<\/th>\nDoza recomandat\u0103<\/th>\n<\/tr>\n<\/thead>\n
Adul\u021bi cu sindrom al vezicii hiperactive<\/td>\n4 mg o dat\u0103 pe zi<\/strong><\/td>\n<\/tr>\n
Redus la 2 mg o dat\u0103 pe zi dac\u0103<\/td>\nInsuficien\u021b\u0103 hepatic\u0103\/renal\u0103 sever\u0103 (eGFR <30); inhibitor puternic concomitent CYP3A4; metabolizor slab CYP2D6 cu efecte secundare<\/td>\n<\/tr>\n
Afectare hepatic\u0103 sever\u0103 (Child-Pugh C)<\/td>\nEvita\u021bi<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u00cenghiti\u021bi capsula \u00eentreag\u0103<\/strong>, cu sau f\u0103r\u0103 m\u00e2ncare, la aceea\u0219i or\u0103 \u00een fiecare zi. Nu zdrobi\u021bi, mesteca\u021bi sau deschide\u021bi capsula. \u00cembun\u0103t\u0103\u021birea \u00eencepe \u00een 1-2 s\u0103pt\u0103m\u00e2ni; beneficiul complet \u00een 4-8 s\u0103pt\u0103m\u00e2ni. Dac\u0103 nu exist\u0103 efect util la 8 s\u0103pt\u0103m\u00e2ni, reevalua\u021bi.<\/p>\n

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\u26a0 Avertisment despre denumire vs molecul\u0103<\/strong><\/p>\n

Denumirea comercial\u0103 Urotel XL<\/strong> con\u021bine silaba \u201curotel\u201d pe care unii cump\u0103r\u0103tori o asociaz\u0103 cu alpha-blocantele (Urief\/Urotel) pentru HBP. Nu prime\u0219te,<\/strong> presupune\u021bi c\u0103 acesta este un alpha-blocant. Urotel XL este un antimuscarinic pentru sindromul vezicii hiperactive<\/strong> \u2014 o clas\u0103 diferit\u0103 cu indica\u021bii diferite. Dac\u0103 ave\u021bi obstruc\u021bie legat\u0103 de BPH, ave\u021bi nevoie de un blocant alfa (silodosin, alfuzosin, tamsulosin), nu de tolterodin.<\/p>\n<\/div>\n

Efecte secundare<\/h2>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Efect secundar<\/th>\nFrecven\u021b\u0103<\/th>\nNote<\/th>\n<\/tr>\n<\/thead>\n
Gur\u0103 uscat\u0103<\/td>\nFoarte frecvent (~25% IR \/ ~17% ER)<\/td>\nHidratare, gum\u0103 f\u0103r\u0103 zah\u0103r<\/td>\n<\/tr>\n
Constipa\u021bie<\/td>\nFrecvent (~7%)<\/td>\nFibre, lichide; laxativ cu volum dac\u0103 este necesar<\/td>\n<\/tr>\n
Ochi usca\u021bi<\/td>\nFrecvente<\/td>\nPic\u0103turi lubrifiante<\/td>\n<\/tr>\n
Dureri de cap<\/td>\nFrecvente<\/td>\nDe obicei se amelior\u0103 \u00een 2 s\u0103pt\u0103m\u00e2ni<\/td>\n<\/tr>\n
Indigestie<\/td>\nFrecvente<\/td>\nLua\u021bi cu m\u00e2ncare<\/td>\n<\/tr>\n
Somnolen\u021b\u0103, vedere \u00eence\u021bo\u0219at\u0103<\/td>\nFrecvente<\/td>\nEvita\u021bi condusul p\u00e2n\u0103 v\u0103 obi\u0219nui\u021bi<\/td>\n<\/tr>\n
Reten\u021bie urinar\u0103<\/td>\nPu\u021bin frecvente<\/td>\n\u00centrerupe\u021bi \u0219i consulta\u021bi medicul<\/td>\n<\/tr>\n
Prelungire QT (doze mari)<\/td>\nRare<\/td>\nEvita\u021bi combinarea cu alte medicamente care prelungesc QT<\/td>\n<\/tr>\n
Glaucom cu unghi \u00eenchis acut<\/td>\nRare<\/td>\nOftalmologie \u00een aceea\u0219i zi pentru dureri oculare<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Interac\u021biuni medicamentoase<\/h2>\n\n\n\n\n\n\n\n\n\n
Combina\u021bie<\/th>\nEfect<\/th>\nAc\u021biune<\/th>\n<\/tr>\n<\/thead>\n
Inhibitori puternici ai CYP3A4 (ketoconazol, ritonavir, claritromicin\u0103)<\/td>\nNivelurile de tolterodin\u0103 cresc \u2014 risc de efecte QT<\/td>\nReduce\u021bi la 2 mg\/zi<\/td>\n<\/tr>\n
Inhibitori puternici ai CYP2D6 (fluoxetin\u0103, paroxetin\u0103)<\/td>\nTolterodina se acumuleaz\u0103<\/td>\nMonitoriza\u021bi efectele adverse<\/td>\n<\/tr>\n
Alte anticholinergice (oxibutinin\u0103, antidepresive triciclice, antihistaminice sedative)<\/td>\nPovara aditiv\u0103<\/td>\nEvita\u021bi suprapunerea<\/td>\n<\/tr>\n
Medicamente care prelungesc intervalul QT (sotalol, amiodaron\u0103, metadon\u0103, ondansetron, citalopram > 20 mg)<\/td>\nRisc QT aditiv<\/td>\nEvita\u021bi combina\u021bia<\/td>\n<\/tr>\n
Warfarin<\/td>\nNicio interac\u021biune clinic semnificativ\u0103<\/td>\nMonitorizarea standard a INR<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Cine nu ar trebui s\u0103 ia Urotel XL<\/h2>\n