{"id":56583,"date":"2024-02-27T16:59:57","date_gmt":"2024-02-27T16:59:57","guid":{"rendered":"https:\/\/medsname.com\/dexona-injection\/"},"modified":"2026-05-01T10:49:13","modified_gmt":"2026-05-01T10:49:13","slug":"dexona-injection","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ro\/product\/dexona-injection\/","title":{"rendered":"Injectie Dexona"},"content":{"rendered":"

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\u26a1 R\u0103spuns rapid \u2014 Ce este Dexona Injectabil?<\/h3>\n

Injectie Dexona<\/strong> este un fosfat de dexametazon sodic 4 mg\/mL solu\u021bie<\/strong> furnizat \u00een ampole de 2 mL (8 mg total)<\/strong>, pentru intramuscular sau intravenos<\/strong> utilizare. Este glucocorticul de lung\u0103 ac\u021biune de elec\u021bie pentru administrare parenteral\u0103 atunci c\u00e2nd este necesar\u0103 administrare IV sau IM \u0219i c\u00e2nd activitatea mineralocorticoid\u0103 (de re\u021binere a s\u0103rurilor) nu este dorit\u0103 \u2014 edem cerebral, acoperire anti-emetic\u0103 \u00een timpul chimioterapiei, astm acut sever, reac\u021bii alergice acute \u0219i maturare pulmonar\u0103 fetal\u0103 antenatal\u0103. Doza tipic\u0103 pentru adul\u021bi este de 4\u20138 mg IM\/IV<\/strong>, repetat\u0103 \u00een func\u021bie de contextul clinic.<\/p>\n<\/div>\n

\nCe beneficii ofer\u0103 MedsBase:<\/strong> Produc\u0103tor certificat WHO-GMP \u00b7 Ambalaj discret \u00b7 Livrare la nivel mondial \u00b7 Peste 1.400 de recenzii verificate ale clien\u021bilor<\/a>\n<\/div>\n

\ud83d\udce6 Fiecare comand\u0103 este acoperit\u0103 de politica noastr\u0103 de Politica noastr\u0103 de Reexpediere Garantat\u0103<\/strong><\/a> \u2014 dac\u0103 coletul dumneavoastr\u0103 nu sose\u0219te \u00een 20 de zile lucr\u0103toare, \u00eel relivr\u0103m.<\/p>\n

De ce s\u0103 comanzi de la MedsBase<\/h3>\n

Medicamentele noastre generice sunt procurate de la produc\u0103tori certifica\u021bi WHO-GMP \u0219i expediate la nivel mondial \u00een ambalaje discrete \u0219i simple \u2014 f\u0103r\u0103 denumirea medicamentului pe exteriorul coletului. Pl\u0103\u021bile cu cardul sunt procesate printr-un procesor reglementat (descrierile de pe extrasul de cont includ un procesor de pl\u0103\u021bi cu card reglementat \u2014 niciodat\u0103 \u201cMedsBase\u201d sau numele vreunui medicament). Accept\u0103m \u0219i criptomonede \u0219i transferuri bancare SEPA. Fiecare comand\u0103 este sus\u021binut\u0103 de Politica noastr\u0103 de Asigurare pentru Relivrare.<\/p>\n

Dexona Injectabil 4 mg\/mL (ampol\u0103 de 2 mL)<\/strong> este o solu\u021bie steril\u0103 de dexamethasone sodium phosphate<\/strong>, sarea solubil\u0103 \u00een ap\u0103 a dexametazonei care permite administrarea rapid\u0103 intravenoas\u0103 sau intramuscular\u0103. Fiecare flacon de 2 mL con\u021bine 8 mg de dexametazon\u0103 \u2014 o doz\u0103 unic\u0103 standard pentru adul\u021bi \u00een majoritatea indica\u021biilor acute.<\/p>\n

Injectarea este preferat\u0103 \u00een locul dexametazonei orale atunci c\u00e2nd:<\/p>\n

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  • Este necesar un efect sistemic rapid (reac\u021bii alergice acute, edem cerebral, astm sever)<\/li>\n
  • Pacientul nu poate \u00eenghi\u021bi (post-operator, post-accident vascular cerebral, v\u0103rs\u0103turi, con\u0219tiin\u021b\u0103 alterat\u0103)<\/li>\n
  • Este esen\u021bial\u0103 o biodisponibilitate fiabil\u0103 (afec\u021biuni gastrointestinale, v\u0103rs\u0103turi, malabsorb\u021bie)<\/li>\n
  • Este dorit un efect IM depo (maturare pulmonar\u0103 antenatal\u0103)<\/li>\n<\/ul>\n

    Pentru ce se utilizeaz\u0103 injectia Dexona?<\/h2>\n
      \n
    • Edem cerebral<\/strong> de la tumori cerebrale \u2014 doz\u0103 de \u00eenc\u0103rcare IV, apoi trecere la administrare oral\u0103<\/li>\n
    • Acoperire anti-emetic\u0103 pentru chimioterapie<\/strong> \u2014 8\u201312 mg IV \u00eenainte de regimuri emetogene ridicate<\/li>\n
    • Exacerbare acut\u0103 de astm sever sau BPOC<\/strong> \u2014 8 mg IV\/IM doz\u0103 unic\u0103<\/li>\n
    • Reac\u021bii alergice acute, anafilaxie<\/strong> \u2014 adjunct la adrenalin\u0103<\/li>\n
    • Maturizarea pulmonar\u0103 fetal\u0103 antenatal\u0103<\/strong> \u2014 6 mg IM la fiecare 12 ore x 4 doze (2 zile), \u00eentre 24 \u0219i 34 s\u0103pt\u0103m\u00e2ni de gesta\u021bie<\/li>\n
    • Meningit\u0103 bacterian\u0103<\/strong> \u2014 ca adjunct, 0,15 mg\/kg IV la fiecare 6 ore timp de 2\u20134 zile<\/li>\n
    • Crup la copii<\/strong> \u2014 o singur\u0103 doz\u0103 IM de 0,6 mg\/kg dac\u0103 administrarea oral\u0103 nu este tolerat\u0103<\/li>\n
    • Exacerb\u0103ri acute ale bolilor autoimune<\/strong> \u2014 terapie de punte \u00eenainte de administrarea de steroizi orali<\/li>\n
    • Compresie medular\u0103<\/strong> \u00een neoplasme \u2014 doze mari IV<\/li>\n
    • Tumoare hematologic\u0103<\/strong> \u2014 componente ale chimioterapiei<\/li>\n<\/ul>\n

      Doze Dexona Injec\u021bie<\/h2>\n
        \n
      • Doza general\u0103 acut\u0103 pentru adul\u021bi:<\/strong> 4\u20138 mg IV\/IM la fiecare 6\u201312 ore, ajustat \u00een func\u021bie de r\u0103spuns<\/li>\n
      • Edem cerebral:<\/strong> 10 mg IV ini\u021bial, apoi 4 mg la fiecare 6 ore; trecere la administrare oral\u0103 dup\u0103 3\u20135 zile<\/li>\n
      • Anti-emetic pentru chimioterapie:<\/strong> 8\u201312 mg IV \u00eenainte de tratament, continuat oral timp de 2\u20134 zile<\/li>\n
      • Maturizarea pulmonar\u0103 antenatal\u0103:<\/strong> 6 mg IM la fiecare 12 ore pentru 4 doze<\/li>\n
      • Crup (IM):<\/strong> 0,6 mg\/kg doz\u0103 unic\u0103<\/li>\n
      • Compresiunea m\u0103duvei spin\u0103rii:<\/strong> 16 mg IV ini\u021bial, apoi 4 mg la fiecare 6 ore, cu planificare urgent\u0103 de radioterapie\/chirurgie<\/li>\n<\/ul>\n

        Administrare IV: injectare lent\u0103 pe 1\u20132 minute pentru doze de p\u00e2n\u0103 la 8 mg; dilua\u021bi dozele mai mari pentru perfuzie. Administrare IM: injectare intramuscular\u0103 profund\u0103, cu rota\u021bie a locurilor de injectare. Solu\u021bia poate fi amestecat\u0103 cu lidocain\u0103 pentru injectare articular\u0103 \u0219i \u00een \u021besuturi moi de c\u0103tre speciali\u0219ti.<\/p>\n

        Poten\u021ba \u0219i echivalen\u021ba corticosteroidelor<\/h2>\n

        Diferite corticosteroide difer\u0103 \u00een principal prin poten\u021b\u0103, durat\u0103 de ac\u021biune \u0219i activitate mineralocorticoid\u0103 (de re\u021binere a s\u0103rurilor). Tabelul de mai jos ofer\u0103 echivalen\u021ba clinic\u0103 util\u0103 \u2014 v\u0103 permite s\u0103 converti\u021bi o doz\u0103 dintr-un steroid \u00een doza echivalent\u0103 a altuia.<\/p>\n\n\n\n\n\n\n\n\n\n
        Corticosteroid<\/th>\nPoten\u021b\u0103 glucocorticoid\u0103<\/th>\nDoza echivalent\u0103<\/th>\nMineralocorticoid<\/th>\nDurat\u0103<\/th>\n<\/tr>\n<\/thead>\n
        Hidrocortizon<\/td>\n1 (de referin\u021b\u0103)<\/td>\n20 mg<\/td>\nSubstan\u021bial\u0103<\/td>\n8\u201312 h<\/td>\n<\/tr>\n
        Prednisolon<\/td>\n4<\/td>\n5 mg<\/td>\nSc\u0103zut<\/td>\n12\u201336 h<\/td>\n<\/tr>\n
        Methylprednisolone<\/td>\n5<\/td>\n4 mg<\/td>\nMinim\u0103<\/td>\n12\u201336 h<\/td>\n<\/tr>\n
        Dexametazon\u0103<\/strong><\/td>\n25\u201330<\/td>\n0,75 mg<\/td>\nNiciuna<\/td>\n36\u201354 h<\/td>\n<\/tr>\n
        Betametazon\u0103<\/td>\n25\u201330<\/td>\n0,75 mg<\/td>\nNiciuna<\/td>\n36\u201354 h<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

        Cine nu ar trebui s\u0103 foloseasc\u0103 injectarea Dexona?<\/h2>\n
          \n
        • Infec\u021bie fungic\u0103 sistemic\u0103 (cu excep\u021bia terapiei de substitu\u021bie \u00een insuficien\u021ba adrenal\u0103)<\/li>\n
        • Vaccinuri cu virus viu \u00een timpul dozelor imunosupresoare (consulta\u021bi un specialist \u00eenainte de BCG, MMR, febr\u0103 galben\u0103, varicel\u0103, tifos oral)<\/li>\n
        • Infec\u021bie bacterian\u0103 activ\u0103 netratat\u0103 (\u00eencepe\u021bi mai \u00eent\u00e2i cu antibioticele)<\/li>\n
        • Tuberculoz\u0103 activ\u0103 f\u0103r\u0103 acoperire anti-TB<\/li>\n
        • Hipersensibilitate cunoscut\u0103 la molecula activ\u0103 sau la orice excipient<\/li>\n
        • Folosi\u021bi cu precau\u021bie \u00een: diabet zaharat, insuficien\u021b\u0103 cardiac\u0103 congestiv\u0103, hipertensiune arterial\u0103, osteoporoz\u0103, ulcer peptic, tulbur\u0103ri psihiatrice, glaucom, herpes simplex oftalmic<\/li>\n
        • Sarcina: folosi\u021bi numai dac\u0103 este clar necesar \u2014 prednisolonul \u0219i hidrocortizonul trec mai pu\u021bin prin placent\u0103 dec\u00e2t dexametazonul\/betametazonul, care sunt preferate atunci c\u00e2nd se dore\u0219te un efect fetal (de ex. maturarea pl\u0103m\u00e2nilor)<\/li>\n<\/ul>\n

          Efecte Secundare ale Corticosteroidelor<\/h2>\n

          Efectele secundare ale corticosteroidelor depind de doz\u0103 \u0219i de durat\u0103. Tratamentele scurte (< 2 s\u0103pt\u0103m\u00e2ni) la doze moderate sunt de obicei bine tolerate. Terapiile mai lungi sau la doze mai mari produc profilul clasic \u201cCushingoid\u201d.<\/p>\n

          Pe termen scurt (primele 1\u20132 s\u0103pt\u0103m\u00e2ni):<\/strong><\/p>\n