{"id":56683,"date":"2024-02-27T17:03:35","date_gmt":"2024-02-27T17:03:35","guid":{"rendered":"https:\/\/medsname.com\/duvanta\/"},"modified":"2026-04-30T10:24:36","modified_gmt":"2026-04-30T10:24:36","slug":"duvanta","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ro\/product\/duvanta\/","title":{"rendered":"Duvanta"},"content":{"rendered":"

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\u26a1 R\u0103spuns rapid<\/h3>\n

Duvanta (Duloxetin\u0103 20 \/ 30 \/ 40 \/ 60 mg) este un inhibitor al recapt\u0103rii serotonin\u0103-noradrenalin\u0103 utilizat pentru depresie major\u0103, anxietate generalizat\u0103, neuropatie diabetic\u0103 periferic\u0103, fibromialgie \u0219i dureri musculo-scheletice cronice. Deosebit de util\u0103 c\u00e2nd depresia este asociat\u0103 cu durere cronic\u0103.<\/p>\n<\/div>\n

\nCe beneficii ofer\u0103 MedsBase:<\/strong> Produc\u0103tor certificat WHO-GMP \u00b7 Ambalaj discret \u00b7 Livrare la nivel mondial \u00b7 Peste 1.400 de recenzii verificate ale clien\u021bilor<\/a>\n<\/div>\n

\ud83d\udce6 Fiecare comand\u0103 este acoperit\u0103 de politica noastr\u0103 de Politica noastr\u0103 de Reexpediere Garantat\u0103<\/strong><\/a> \u2014 dac\u0103 coletul dumneavoastr\u0103 nu sose\u0219te \u00een 20 de zile lucr\u0103toare, \u00eel relivr\u0103m.<\/p>\n

De ce s\u0103 comanzi de la MedsBase<\/h3>\n

Duvanta de la MedsBase este furnizat\u0103 direct de la un produc\u0103tor certificat WHO-GMP \u00een ambalaj simplu \u0219i discret. Fiecare comand\u0103 este acoperit\u0103 de Politica noastr\u0103 de Reexpediere Garantat\u0103<\/a> \u2014 perioad\u0103 de livrare de 20 de zile lucr\u0103toare sau retrimitem f\u0103r\u0103 costuri suplimentare \u2014 \u0219i se calific\u0103 pentru programul nostru de loialitate pentru clien\u021bi<\/a>. Livr\u0103rile sunt disponibile \u00een majoritatea destina\u021biilor la nivel mondial.<\/p>\n

Ce este Duvanta \u0219i cum func\u021bioneaz\u0103<\/h2>\n

Duvanta este o capsulel\u0103 cu eliberare \u00eent\u00e2rziat\u0103 de duloxetin\u0103 \u00een doze de 20\/30\/40\/60 mg, furnizat\u0103 de Intas. Duloxetina este un inhibitor echilibrat al recapt\u0103rii at\u00e2t a serotoninei (5-HT), c\u00e2t \u0219i a noradrenalinei (NA) la nivelul transportorilor presinaptici. Profilul dual de ac\u021biune este ceea ce o face eficient\u0103 at\u00e2t pentru tulbur\u0103rile de stare a spiritului, c\u00e2t \u0219i pentru durere.<\/p>\n

Efectul terapeutic asupra st\u0103rii de spirit \u0219i anxietate se dezvolt\u0103 \u00een 4\u20136 s\u0103pt\u0103m\u00e2ni; efectele analgezice asupra durerii neuropatice \u0219i musculo-scheletice apar adesea \u00een 1\u20132 s\u0103pt\u0103m\u00e2ni la aceea\u0219i doz\u0103.<\/p>\n

Indica\u021bii \u0219i dozaj<\/h2>\n\n\n\n\n\n\n\n\n\n\n
Indica\u021bie<\/th>\nDoza ini\u021bial\u0103<\/th>\n\u021aint\u0103<\/th>\nMaxim<\/th>\n<\/tr>\n<\/thead>\n
Depresie major\u0103<\/td>\n30 mg OD \u00d7 1 s\u0103pt\u0103m\u00e2n\u0103<\/td>\n60 mg OD<\/td>\n120 mg (\u00eemp\u0103r\u021bit BID)<\/td>\n<\/tr>\n
Anxietate generalizat\u0103<\/td>\n30 mg OD \u00d7 1 s\u0103pt\u0103m\u00e2n\u0103<\/td>\n60 mg OD<\/td>\n120 mg<\/td>\n<\/tr>\n
Neuropatie diabetic\u0103 periferic\u0103<\/td>\n30 mg OD \u00d7 1 s\u0103pt\u0103m\u00e2n\u0103<\/td>\n60 mg OD<\/td>\n60 mg<\/td>\n<\/tr>\n
Fibromialgie<\/td>\n30 mg OD \u00d7 1 s\u0103pt\u0103m\u00e2n\u0103<\/td>\n60 mg OD<\/td>\n60 mg<\/td>\n<\/tr>\n
Durere cronic\u0103 musculo-scheletic\u0103<\/td>\n30 mg OD \u00d7 1 s\u0103pt\u0103m\u00e2n\u0103<\/td>\n60 mg OD<\/td>\n60 mg<\/td>\n<\/tr>\n
Incontinenta urinar\u0103 de stres (off-label, UE)<\/td>\n20 mg de 2 ori pe zi<\/td>\n40 mg BID<\/td>\n40 mg BID<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Considera\u021bii importante de siguran\u021b\u0103<\/h2>\n
\nHepatic \u2014 evita\u021bi \u00een cazul consumului semnificativ de alcool sau a insuficien\u021bei hepatice<\/strong><\/p>\n

Duloxetina are un semnal de hepatotoxicitate de baz\u0103 care devine clinic semnificativ la pacien\u021bii cu consum semnificativ de alcool (\u22653 b\u0103uturi\/zi) sau boal\u0103 hepatic\u0103 cronic\u0103. Evita\u021bi \u00een orice insuficien\u021b\u0103 hepatic\u0103 clinic semnificativ\u0103.<\/strong> Verifica\u021bi testele hepatice ini\u021biale la adul\u021bii \u00een v\u00e2rst\u0103 \u0219i pacien\u021bii care iau multiple medicamente metabolizate hepatic.<\/p>\n<\/div>\n

\nTensiune arterial\u0103<\/strong><\/p>\n

Duloxetina produce o cre\u0219tere mic\u0103, dar real\u0103 a tensiunii arteriale \u2014 \u00een medie +2\u20133 mmHg sistolic\u0103 la doze terapeutice. Mai pu\u021bin dec\u00e2t venlafaxina, dar suficient pentru a conta \u00een hipertensiunea slab controlat\u0103. Verifica\u021bi tensiunea arterial\u0103 la \u00eenceput, dup\u0103 2 s\u0103pt\u0103m\u00e2ni \u0219i la fiecare cre\u0219tere de doz\u0103.<\/p>\n<\/div>\n

\nSindrom de \u00eentrerupere<\/strong><\/p>\n

Duloxetina are un timp de \u00eenjum\u0103t\u0103\u021bire de eliminare scurt (12 ore) \u2014 \u00eentreruperea brusc\u0103 poate provoca ame\u021beal\u0103, parestezii (\u201c\u0219ocuri electrice\u201d), grea\u021b\u0103, cefalee \u0219i disforie \u00een decurs de 24\u201372 de ore. Reduce\u021bi treptat doza pe o perioad\u0103 de cel pu\u021bin 2\u20134 s\u0103pt\u0103m\u00e2ni. Cea mai mic\u0103 doz\u0103 disponibil\u0103 \u00een capsule (20 mg sau 30 mg, \u00een func\u021bie de pia\u021b\u0103) stabile\u0219te limita minim\u0103 de reducere \u2014 \u00een practica clinic\u0103, con\u021binutul capsulei este uneori \u00eemp\u0103r\u021bit pentru ultima etap\u0103 de reducere.<\/p>\n<\/div>\n

\nAvertisment cutie neagr\u0103 privind riscul de suicid (sub 25 de ani)<\/strong><\/p>\n

Toate antidepresivele poart\u0103 un avertisment cutie neagr\u0103 FDA privind cre\u0219terea g\u00e2ndurilor suicidare la pacien\u021bii sub 25 de ani.<\/p>\n<\/div>\n

Efecte secundare frecvente<\/h2>\n