{"id":57949,"date":"2024-02-27T18:09:12","date_gmt":"2024-02-27T18:09:12","guid":{"rendered":"https:\/\/medsname.com\/atarise\/"},"modified":"2026-04-30T10:24:19","modified_gmt":"2026-04-30T10:24:19","slug":"atarise","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ro\/product\/atarise\/","title":{"rendered":"Atarise"},"content":{"rendered":"

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\u26a1 R\u0103spuns rapid<\/h3>\n

Atarise (Hydroxyzine 10\/25 mg) este un antihistaminic sedativ de prim\u0103 genera\u021bie \u0219i anxiolitic cu ac\u021biune central\u0103. Utilizat pentru anxietate pe termen scurt, sedare preprocedural\u0103, prurit alergic \u0219i urticarie, precum \u0219i ca antiemetic. Neadictiv \u2014 util c\u00e2nd benzodiazepinele sunt nepotrivite.<\/p>\n<\/div>\n

\nCe beneficii ofer\u0103 MedsBase:<\/strong> Produc\u0103tor certificat WHO-GMP \u00b7 Ambalaj discret \u00b7 Livrare la nivel mondial \u00b7 Peste 1.400 de recenzii verificate ale clien\u021bilor<\/a>\n<\/div>\n

\ud83d\udce6 Fiecare comand\u0103 este acoperit\u0103 de politica noastr\u0103 de Politica noastr\u0103 de Reexpediere Garantat\u0103<\/strong><\/a> \u2014 dac\u0103 coletul dumneavoastr\u0103 nu sose\u0219te \u00een 20 de zile lucr\u0103toare, \u00eel relivr\u0103m.<\/p>\n

De ce s\u0103 comanzi de la MedsBase<\/h3>\n

Atarise de la MedsBase este furnizat direct de la un produc\u0103tor certificat WHO-GMP \u00een ambalaj simplu \u0219i discret. Fiecare comand\u0103 este acoperit\u0103 de Politica noastr\u0103 de Reexpediere Garantat\u0103<\/a> \u2014 perioad\u0103 de livrare de 20 de zile lucr\u0103toare sau retrimitem f\u0103r\u0103 costuri suplimentare \u2014 \u0219i se calific\u0103 pentru programul nostru de loialitate pentru clien\u021bi<\/a>. Livr\u0103rile sunt disponibile \u00een majoritatea destina\u021biilor la nivel mondial.<\/p>\n

Ce este Atarise \u0219i cum func\u021bioneaz\u0103<\/h2>\n

Atarise este un comprimat de hydroxyzine 10\/25 mg furnizat de Sun Pharma. Hydroxyzina este un antihistaminic de prim\u0103 genera\u021bie din clasa piperazinelor cu antagonism puternic H1 central, antagonism slab 5-HT2A \u0219i activitate anticolinergic\u0103 moderat\u0103. Componenta H1 traverseaz\u0103 bariera hemato-encefalic\u0103 \u0219i st\u0103 la baza efectului sedativ \u0219i anxiolitic.<\/p>\n

Hydroxyzina este una dintre pu\u021binele op\u021biuni non-benzodiazepinice \u0219i non-barbiturice pentru ameliorarea anxiet\u0103\u021bii PRN \u2014 efect \u00een 30\u201360 de minute, durat\u0103 de 4\u20136 ore.<\/p>\n

Indica\u021bii \u0219i dozaj<\/h2>\n\n\n\n\n\n\n\n\n\n\n\n
Indica\u021bie<\/th>\nDoza pentru adul\u021bi<\/th>\nNote<\/th>\n<\/tr>\n<\/thead>\n
Anxietate acut\u0103\/agitare<\/td>\n25\u2013100 mg PO\/IM, se poate repeta la fiecare 6 ore<\/td>\nMaxim 400 mg\/zi<\/td>\n<\/tr>\n
Prurit\/urticarie<\/td>\n25 mg de 3\u20134 ori pe zi<\/td>\nMaxim 100 mg de 4 ori pe zi<\/td>\n<\/tr>\n
Sedare preoperatorie<\/td>\n50\u2013100 mg cu 1 or\u0103 \u00eenainte de interven\u021bie<\/td>\n\u2014<\/td>\n<\/tr>\n
Antiemetic<\/td>\n25\u2013100 mg IM<\/td>\nDoar pentru adul\u021bi<\/td>\n<\/tr>\n
Insomnie (off-label)<\/td>\n25\u201350 mg HS<\/td>\nDoar pe termen scurt<\/td>\n<\/tr>\n
Prurit pediatric \/ sedare<\/td>\n0,5\u20131 mg\/kg\/doz\u0103 la fiecare 6 ore<\/td>\n\u2014<\/td>\n<\/tr>\n
Pacien\u021bi \u00een v\u00e2rst\u0103 (orice indica\u021bie)<\/td>\n\u00eencepe cu 10\u201325 mg<\/td>\nRisc QT \u0219i risc de c\u0103deri<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Considera\u021bii importante de siguran\u021b\u0103<\/h2>\n
\nPrelungire QT \u2014 restric\u021bie EMA 2015<\/strong><\/p>\n

Hydroxyzina prelunge\u0219te intervalul QT \u00eentr-o manier\u0103 dependent\u0103 de doz\u0103. EMA a impus restric\u021bii de dozaj \u00een 2015: maximum 100 mg\/zi la adul\u021bi, 50 mg\/zi la persoanele \u00een v\u00e2rst\u0103 \u0219i 2 mg\/kg\/zi la copii<\/strong>. Evita\u021bi \u00een cazul prelungirii QT cunoscute, hipokaliemie\/hipomagneziemie, infarct miocardic recent, insuficien\u021b\u0103 cardiac\u0103 necompensat\u0103 \u0219i medicamente concomitente care prelungesc QT (azole, macrolide, fluoroquinolone, metadon\u0103, ondansetron, antipsihotice). ECG pre-terapeutic recomandat la persoanele \u00een v\u00e2rst\u0103.<\/p>\n<\/div>\n

\n\u00cenc\u0103rc\u0103tur\u0103 anticolinergic\u0103<\/strong><\/p>\n

Hydroxyzina are o activitate anticolinergic\u0103 semnificativ\u0103 \u2014 relevant\u0103 \u00een special la persoanele \u00een v\u00e2rst\u0103 (medica\u021bie poten\u021bial inadecvat\u0103 conform Criteriilor Beers). Evita\u021bi \u00een glaucom cu unghi \u00eengust, HBP cu reten\u021bie, demen\u021b\u0103, constipa\u021bie sever\u0103. Societatea American\u0103 de Geriatrie descurajeaz\u0103 utilizarea antihistaminicelor de prima genera\u021bie ca agen\u021bi PRN la persoanele \u00een v\u00e2rst\u0103.<\/p>\n<\/div>\n

\nSedare \u0219i conducere<\/strong><\/p>\n

Sedarea dup\u0103 o singur\u0103 doz\u0103 poate persista 6+ ore; evita\u021bi conducerea \u0219i utilizarea ma\u0219inilor p\u00e2n\u0103 c\u00e2nd se cunoa\u0219te tolerabilitatea. Deosebit de problematic la pacien\u021bii chirurgicali naive la opioide \u00een ziua extern\u0103rii.<\/p>\n<\/div>\n

Efecte secundare frecvente<\/h2>\n