{"id":59216,"date":"2024-02-28T05:46:24","date_gmt":"2024-02-28T05:46:24","guid":{"rendered":"https:\/\/medsname.com\/meta-spray\/"},"modified":"2026-05-01T10:49:15","modified_gmt":"2026-05-01T10:49:15","slug":"meta-spray","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ro\/product\/meta-spray\/","title":{"rendered":"Meta Spray"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Meta Spray?<\/h3>\n<p style=\"margin:0;\"><strong>Meta Spray<\/strong> is a nasal spray containing <strong>mometasone furoate monohydrate<\/strong> (50 \u00b5g\/spray (10 g \/ ~140 doses) &mdash; typically 50&nbsp;&micro;g per spray), an <strong>intranasal corticosteroid (INCS)<\/strong> utilizat pentru <strong>seasonal and perennial allergic rhinitis (hay fever), non-allergic rhinitis, nasal polyps, and sinusitis<\/strong>. It reduces inflammation directly in the nasal lining &mdash; the most effective single-drug class for moderate-to-severe allergic rhinitis (ARIA and AAAAI guidelines). Usual dose: 2 sprays per nostril once daily. <strong>\u00cenceput:<\/strong> some effect within 12 hours, full effect at 1&ndash;2 weeks. Systemic absorption is very low (&lt; 0.1%) &mdash; long-term daily use is well-tolerated. Main side effects: mild nasal irritation, dryness, occasional nosebleeds. Suitable for adults and children from age 2 (dose-adjusted). Prime the bottle before first use.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Ce beneficii ofer\u0103 MedsBase:<\/strong> Produc\u0103tor certificat WHO-GMP \u00b7 Ambalaj discret \u00b7 Livrare la nivel mondial \u00b7 Peste 1.400 de recenzii verificate <a href=\"https:\/\/medsbase.com\/ro\/reviews\/\">ale clien\u021bilor<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Fiecare comand\u0103 este acoperit\u0103 de politica noastr\u0103 de <a href=\"https:\/\/medsbase.com\/ro\/medsbase-re-shipment-assurance-policy\/\"><strong>Politica noastr\u0103 de Reexpediere Garantat\u0103<\/strong><\/a> \u2014 dac\u0103 coletul dumneavoastr\u0103 nu sose\u0219te \u00een 20 de zile lucr\u0103toare, \u00eel relivr\u0103m.<\/p>\n<h3>De ce s\u0103 comanzi de la MedsBase<\/h3>\n<p>Medicamentele noastre generice sunt procurate de la produc\u0103tori certifica\u021bi WHO-GMP \u0219i expediate la nivel mondial \u00een ambalaje discrete \u0219i simple \u2014 f\u0103r\u0103 denumirea medicamentului pe exteriorul coletului. Pl\u0103\u021bile cu cardul sunt procesate printr-un procesor reglementat (descrierile de pe extrasul de cont includ un procesor de pl\u0103\u021bi cu card reglementat \u2014 niciodat\u0103 \u201cMedsBase\u201d sau numele vreunui medicament). Accept\u0103m \u0219i criptomonede \u0219i transferuri bancare SEPA. Fiecare comand\u0103 este sus\u021binut\u0103 de Politica noastr\u0103 de Asigurare pentru Relivrare.<\/p>\n<h2 class=\"wp-block-heading\">What Is Meta Spray?<\/h2>\n<p>Meta Spray is a <strong>metered-dose aqueous nasal spray<\/strong> care con\u021bin <strong>mometasone furoate<\/strong> (50 \u00b5g\/spray (10 g \/ ~140 doses)), manufactured by WHO-GMP certified manufacturer. Supplied as 1, 2 or 3 bottles. Each spray delivers approximately 50&nbsp;&micro;g of mometasone directly onto the nasal mucosa.<\/p>\n<p>Mometasone is a potent, lipophilic corticosteroid with very high topical activity and near-zero systemic bioavailability (&lt; 0.1% by mouth). This combination makes it ideal for intranasal use &mdash; the drug acts right where the inflammation is, with minimal impact on the rest of the body. Originator brand: <strong>Nasonex<\/strong> (Schering-Plough \/ Merck, approved 1997).<\/p>\n<h2 class=\"wp-block-heading\">What Is Meta Spray Used For?<\/h2>\n<ul>\n<li><strong>Rinit\u0103 alergic\u0103 sezonier\u0103 (febr\u0103 de f\u00e2n)<\/strong> &mdash; the most effective single therapy for sneezing, nasal congestion, runny nose, itchy nose<\/li>\n<li><strong>Rinit\u0103 alergic\u0103 peren\u0103<\/strong> &mdash; dust mite, pet dander, mould-driven symptoms year-round<\/li>\n<li><strong>Polipi nazali<\/strong> &mdash; reduces size and prevents recurrence<\/li>\n<li><strong>Acute rhinosinusitis<\/strong> (adjunctive) &mdash; shortens duration of congestion<\/li>\n<li><strong>Non-allergic vasomotor rhinitis<\/strong> &mdash; reduces congestion and drip<\/li>\n<\/ul>\n<p>Intranasal corticosteroids treat the <strong>blocked nose (congestion)<\/strong> component of allergic rhinitis better than any other drug class &mdash; oral antihistamines are generally poor at relieving congestion.<\/p>\n<h2 class=\"wp-block-heading\">How Does Meta Spray Work?<\/h2>\n<p>Mometasone binds intracellular glucocorticoid receptors in the nasal mucosa. The receptor-drug complex moves into the cell nucleus and alters the transcription of dozens of inflammatory genes:<\/p>\n<ul>\n<li><strong>Suprim\u0103<\/strong> production of inflammatory cytokines (IL-4, IL-5, IL-13), chemokines, and adhesion molecules<\/li>\n<li><strong>Reduce<\/strong> eosinophil infiltration and mast-cell activation<\/li>\n<li><strong>Stabilizeaz\u0103<\/strong> vascular permeability &mdash; less swelling, less mucus<\/li>\n<li><strong>Downregulates<\/strong> late-phase allergic response (the congestion that kicks in hours after allergen exposure)<\/li>\n<\/ul>\n<p>Unlike antihistamines, which block only the H1 arm of the allergic cascade, corticosteroids suppress the whole inflammatory network. This is why INCS are the most effective single-drug class for moderate-to-severe allergic rhinitis.<\/p>\n<p><strong>Onset and duration:<\/strong><\/p>\n<ul>\n<li><strong>First noticeable effect:<\/strong> 6&ndash;12 hours after the first dose<\/li>\n<li><strong>Meaningful symptom relief:<\/strong> 1\u20133 zile<\/li>\n<li><strong>Full effect:<\/strong> 1&ndash;2 weeks of daily use<\/li>\n<li><strong>For best seasonal results:<\/strong> start 2 weeks before your expected trigger season and continue daily<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Doza \u0219i administrare<\/h2>\n<p><strong>Adul\u021bi \u0219i copii cu v\u00e2rsta de 12 ani \u0219i peste:<\/strong> 2 sprays (50&nbsp;&micro;g each, total 100&nbsp;&micro;g) in each nostril once daily &mdash; usual total dose 200&nbsp;&micro;g\/day. Once good symptom control is achieved, step down to 1 spray per nostril daily if possible.<\/p>\n<p><strong>Children 2&ndash;11 years:<\/strong> 1 spray in each nostril once daily (total 100&nbsp;&micro;g\/day).<\/p>\n<p><strong>Nasal polyps (adults):<\/strong> 2 sprays per nostril twice daily until response, then 2 sprays per nostril once daily maintenance.<\/p>\n<p><strong>Tehnic\u0103:<\/strong><\/p>\n<ol>\n<li><strong>Preg\u0103ti\u021bi flaconul<\/strong> before first use &mdash; press the pump 10 times until a fine mist appears. Re-prime (2 sprays) if not used for 14+ days.<\/li>\n<li>Blow your nose gently to clear mucus.<\/li>\n<li>\u021aine\u021bi flaconul vertical \u0219i \u00eenclina\u021bi u\u0219or capul \u00eenainte.<\/li>\n<li>Introduce\u021bi duza \u00eentr-o nar\u0103, \u00eenclinat\u0103 <strong>departe de septul nazal<\/strong> (toward the outer wall of the nose) &mdash; this reduces septal irritation and epistaxis.<\/li>\n<li>Breathe in gently through that nostril as you spray; avoid sniffing hard (the medicine should stay in the nose, not run down the throat).<\/li>\n<li>Repeta\u021bi \u00een cealalt\u0103 nar\u0103.<\/li>\n<li>\u0218terge\u021bi duza cu un \u0219erve\u021bel curat \u0219i pune\u021bi capacul la loc.<\/li>\n<\/ol>\n<p><strong>A\u021bi omis o doz\u0103?<\/strong> Take it as soon as you remember. If nearly time for the next dose, skip and continue as normal. Do not double up.<\/p>\n<h2 class=\"wp-block-heading\">Efecte Secundare<\/h2>\n<p>Intranasal corticosteroids are generally very well tolerated. Systemic absorption is &lt; 0.1% of the topical dose.<\/p>\n<p><strong>Efecte adverse frecvente (locale):<\/strong><\/p>\n<ul>\n<li>Nasal irritation, burning or stinging<\/li>\n<li>Dryness inside the nose<\/li>\n<li>Mild epistaxis (nosebleeds) &mdash; usually prevented by angling the nozzle away from the septum<\/li>\n<li>Throat irritation (if drips backwards), cough<\/li>\n<li>Cefalee u\u0219oar\u0103<\/li>\n<\/ul>\n<p><strong>Mai pu\u021bin frecvente:<\/strong><\/p>\n<ul>\n<li>Nasal septum perforation &mdash; very rare; usually associated with aggressive technique or pre-existing septal weakness<\/li>\n<li>Altered taste or smell<\/li>\n<li>Cataracts or raised intraocular pressure &mdash; rare with intranasal use; periodic eye exams sensible for long-term users<\/li>\n<li>Candida (thrush) of the nose or throat &mdash; rare<\/li>\n<li>Reac\u021bii de hipersensibilitate<\/li>\n<\/ul>\n<p><strong>Copii:<\/strong> long-term daily use has been associated with a <strong>small reduction in growth velocity<\/strong> (~0.5 cm\/year in some studies), without reducing final adult height in most trials. Use the lowest effective dose in children and monitor growth.<\/p>\n<h2 class=\"wp-block-heading\">Interac\u021biuni medicamentoase<\/h2>\n<ul>\n<li><strong>Inhibitori puternici ai CYP3A4<\/strong> (ritonavir, ketoconazole, itraconazole) &mdash; can modestly raise systemic mometasone levels; clinical significance is small at intranasal doses.<\/li>\n<li><strong>Other corticosteroids<\/strong> (oral, inhaled, topical) &mdash; cumulative HPA-axis effects if taken long-term at high doses; individually monitor.<\/li>\n<li><strong>Vaccinuri cu virus viu<\/strong> \u2014 nicio interac\u021biune semnificativ\u0103 la dozele intranazale.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Who Should Not Use Meta Spray?<\/h2>\n<ul>\n<li>Known hypersensitivity to mometasone<\/li>\n<li>Untreated local nasal infection (bacterial, fungal, herpes simplex) &mdash; treat the infection first<\/li>\n<li>Recent nasal surgery or nasal trauma &mdash; avoid until healing is complete<\/li>\n<li>Children below the manufacturer&rsquo;s age cutoff<\/li>\n<li>Pregnancy and breastfeeding &mdash; discuss with your doctor; intranasal corticosteroids have a reassuring safety record and are often continued when the benefit outweighs the small theoretical risk<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Depozitare<\/h2>\n<p>Store Meta Spray below 25&deg;C in an upright position, in a dry place. Do not freeze. Keep out of reach of children. Discard per the label&rsquo;s in-use expiry after opening.<\/p>\n<h2 id=\"faqs\">\u00centreb\u0103ri frecvente<\/h2>\n<h3 class=\"wp-block-heading\">Is Meta Spray the same as Nasonex?<\/h3>\n<p>Yes &mdash; Meta Spray contains the same active ingredient (mometasone furoate) at the same strength as Nasonex (Merck). Bioequivalence is required by regulatory authorities, so clinical effect is the same at the same dose.<\/p>\n<h3 class=\"wp-block-heading\">Mometasone vs fluticasone nasal spray &mdash; which is better?<\/h3>\n<p>Head-to-head trials of mometasone (Nasonex) and fluticasone (Flonase) for allergic rhinitis show essentially equivalent clinical effect. Mometasone is once-daily; fluticasone is also once-daily. Choice is usually driven by cost, availability, and personal preference. Both are first-line intranasal corticosteroids.<\/p>\n<h3 class=\"wp-block-heading\">How long does Meta Spray take to work?<\/h3>\n<p>Some effect within 6&ndash;12 hours of the first dose, but the drug needs 1&ndash;2 weeks of daily use to reach full effect. If you expect hay fever in spring, start 2 weeks before your usual trigger season.<\/p>\n<h3 class=\"wp-block-heading\">Can I use Meta Spray daily for months or years?<\/h3>\n<p>Yes &mdash; long-term daily use is well-studied and safe. Because systemic absorption is &lt; 0.1%, there is no meaningful HPA-axis suppression, no bone-density loss, and no cataract\/glaucoma risk at standard intranasal doses in adults. For children, use the lowest effective dose and monitor growth.<\/p>\n<h3 class=\"wp-block-heading\">Why do I get nosebleeds on Meta Spray?<\/h3>\n<p>Mild epistaxis is the most common side effect &mdash; usually from spraying directly at the nasal septum. Angling the nozzle <strong>outward<\/strong> (toward the ear on that side) rather than straight back avoids the septum and dramatically reduces nosebleeds. Saline spray or nasal gel can help dry or irritated passages.<\/p>\n<h3 class=\"wp-block-heading\">Can I combine Meta Spray with an oral antihistamine?<\/h3>\n<p>Yes &mdash; the combination of intranasal corticosteroid + oral 2nd-generation antihistamine is a <strong>standard recommendation for moderate-to-severe allergic rhinitis<\/strong>. The INCS treats congestion; the antihistamine adds itch and sneeze control.<\/p>\n<h3 class=\"wp-block-heading\">Is Meta Spray safe in pregnancy?<\/h3>\n<p>Intranasal corticosteroids have a reassuring safety record in pregnancy (low systemic absorption, no increased teratogenicity signal in cohort data). Many guidelines list intranasal budesonide as first-choice in pregnancy because it has the largest safety dataset, but mometasone and fluticasone are also widely used. Discuss with your obstetrician.<\/p>\n<h3 class=\"wp-block-heading\">Where can I buy Meta Spray online?<\/h3>\n<p>You can order Meta Spray (50 \u00b5g\/spray (10 g \/ ~140 doses)) from MedsBase as 1, 2 or 3 bottles. We ship worldwide with discreet packaging and genuine WHO-GMP certified manufacturer stock.<\/p>\n<h2 class=\"wp-block-heading\">Medicamente conexe pentru alergie<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/ro\/arzep-nasal-spray\/\">Arzep &mdash; Azelastine + Fluticasone nasal spray (step-up)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ro\/allegra\/\">Allegra \u2014 Fexofenadin\u0103 (oral, ne-sedativ)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ro\/xyzal\/\">Xyzal \u2014 Levocetirizin\u0103<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ro\/loratin\/\">Loratin \u2014 Loratadin\u0103<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ro\/okacet\/\">Okacet \u2014 Cetirizin\u0103<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ro\/ocurest-ah-eye-drops\/\">Pic\u0103turi Oculare Ocurest-AH \u2014 pentru ochii iritabili din cauza alergiilor<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ro\/hay-fever-allergies-treatment\/\"><strong>R\u0103sfoi\u021bi toate medicamentele pentru febr\u0103 de f\u00e2n \u0219i alergii<\/strong><\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:24px 0;border-radius:4px;\"><strong>\u2695 Dezaprobare medical\u0103.<\/strong> This page is for informational purposes only and does not replace medical advice from a qualified healthcare professional. Intranasal corticosteroids do not treat anaphylaxis &mdash; a severe allergic reaction is a medical emergency requiring adrenaline (epinephrine) and immediate medical care.<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Alternative conexe<\/h3>\n<p>Alte produse din <strong>Afec\u021biuni cronice<\/strong> pe care clien\u021bii le vizualizeaz\u0103 de asemenea:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/ro\/rasalect\/\">Rasalect<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ro\/entavir\/\">Entavir<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ro\/carvejohn\/\">Carvejohn<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ro\/lemit\/\">Lemit<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ro\/cresar\/\">Cresar<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Reduce congestia nazal\u0103<br \/>\n\u2705 Reduce inflama\u021bia nazal\u0103<br \/>\n\u2705 Aliniaz\u0103 simptomele de alergie<br \/>\n\u2705 Promotes sinus drainage<br \/>\n\u2705 Provides fast relief<\/p>\n<p>Meta Spray contains Momentasone.<\/p>","protected":false},"featured_media":59217,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3975],"product_tag":[4651,4306],"class_list":{"0":"post-59216","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-hay-fever-allergies-treatment","9":"product_tag-meta-spray","10":"product_tag-mometasone","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product\/59216","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/comments?post=59216"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/media\/59217"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/media?parent=59216"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product_brand?post=59216"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product_cat?post=59216"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product_tag?post=59216"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}