{"id":60195,"date":"2024-02-28T06:37:55","date_gmt":"2024-02-28T06:37:55","guid":{"rendered":"https:\/\/medsname.com\/prazinec\/"},"modified":"2026-05-09T11:38:18","modified_gmt":"2026-05-09T11:38:18","slug":"prazinec","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ro\/product\/prazinec\/","title":{"rendered":"Prazinec"},"content":{"rendered":"

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Quick Answer — What is Prazinec?<\/h3>\n
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Prazinec<\/strong> este praziquantel 600 mg<\/strong> de la Sun Pharma<\/strong>. Praziquantel is the WHO Essential Medicine for schistosomiasis, intestinal flukes, liver flukes, and most cestodes including neurocysticercosis<\/strong>. Standard adult dose for schistosomiasis: 40 mg\/kg as a single dose<\/strong>; for tapeworm: 5–10 mg\/kg single dose; for neurocysticercosis: 50 mg\/kg\/day in 3 divided doses for 14–30 days under specialist supervision.<\/p>\n<\/div>\n<\/div>\n

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De ce s\u0103 comanzi de la MedsBase:<\/strong> \u2713 Provenien\u021b\u0103 de la produc\u0103tori certifica\u021bi WHO-GMP<\/strong> \u00b7 \u2713 Ambalaj discret \u00b7 \u2713 Livrare la nivel mondial \u00b7 \u2713 Peste 1.400 de recenzii ale clien\u021bilor<\/strong> la medsbase.com\/reviews<\/a><\/div>\n

\ud83d\udce6 Fiecare comand\u0103 este acoperit\u0103 de politica noastr\u0103 de Politica noastr\u0103 de Reexpediere Garantat\u0103<\/strong><\/a> \u2014 dac\u0103 coletul dumneavoastr\u0103 nu sose\u0219te \u00een 20 de zile lucr\u0103toare, \u00eel relivr\u0103m.<\/p>\n

De ce s\u0103 comanzi de la MedsBase<\/h3>\n

Medicamentele noastre generice sunt procurate de la produc\u0103tori certifica\u021bi WHO-GMP \u0219i expediate la nivel mondial \u00een ambalaje discrete \u0219i simple \u2014 f\u0103r\u0103 denumirea medicamentului pe exteriorul coletului. Pl\u0103\u021bile cu cardul sunt procesate printr-un procesor reglementat (descrierile de pe extrasul de cont includ un procesor de pl\u0103\u021bi cu card reglementat \u2014 niciodat\u0103 \u201cMedsBase\u201d sau numele vreunui medicament). Accept\u0103m \u0219i criptomonede \u0219i transferuri bancare SEPA. Fiecare comand\u0103 este sus\u021binut\u0103 de Politica noastr\u0103 de Asigurare pentru Relivrare.<\/p>\n

What is Prazinec?<\/h2>\n

Prazinec<\/strong> is praziquantel 600 mg from Sun Pharma<\/strong>. Praziquantel is one of the most important drugs in tropical medicine — the global standard for schistosomiasis (which affects roughly 240 million people worldwide), and the agent of choice for most cestode and trematode infections. WHO mass-drug-administration programmes have used praziquantel to treat over a billion people since the 1990s.<\/p>\n

Mecanism de ac\u021biune<\/h2>\n

Praziquantel increases calcium permeability<\/strong> across the parasite tegument (outer covering), causing rapid sustained muscle contraction. This paralyses the worm and exposes its surface antigens to host immune attack — a one-two punch of pharmacological paralysis followed by immune-mediated killing. The mechanism explains why praziquantel works so well in immunocompetent patients and is somewhat less effective in heavily immunosuppressed hosts.<\/p>\n

Oral bioavailability is good (~80%) but first-pass hepatic metabolism is heavy — only about 25% reaches systemic circulation as active drug. Plasma half-life is 1–1.5 hours.<\/p>\n

Prazinec indications and dose<\/h2>\n\n\n\n\n\n\n\n\n\n\n
Indica\u021bie<\/th>\nDoza<\/th>\nProgram<\/th>\n<\/tr>\n<\/thead>\n
Schistosomiasis (S. mansoni, S. haematobium, S. japonicum)<\/td>\n40 mg\/kg<\/td>\nSingle dose (S. japonicum: 60 mg\/kg)<\/td>\n<\/tr>\n
Intestinal tapeworm (Taenia saginata, T. solium)<\/td>\n5–10 mg\/kg<\/td>\nDoza unic\u0103<\/td>\n<\/tr>\n
Hymenolepis nana<\/td>\n25 mg\/kg<\/td>\nSingle dose, repeat at 1 week<\/td>\n<\/tr>\n
Liver flukes (Clonorchis, Opisthorchis)<\/td>\n25 mg\/kg TID<\/td>\nFor 1 day (75 mg\/kg total)<\/td>\n<\/tr>\n
Lung fluke (Paragonimus)<\/td>\n25 mg\/kg TID<\/td>\nFor 2 days<\/td>\n<\/tr>\n
Neurocysticercosis (specialist)<\/td>\n50 mg\/kg\/day in 3 doses<\/td>\nFor 14–30 days WITH steroid cover<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Take with water or a soft drink during or shortly after a meal. Tablets have a bitter taste — do not chew. Children > 4 years: same weight-based dosing applies.<\/p>\n

Neurocysticercosis is a specialist diagnosis.<\/strong> Praziquantel for CNS cysticercosis must be given with concurrent corticosteroid (typically dexamethasone) to suppress the inflammatory response to dying cysts — otherwise raised intracranial pressure can be catastrophic. Imaging (MRI brain) is mandatory before treatment. Do not self-treat suspected neurocysticercosis.<\/div>\n

Efecte secundare<\/h2>\n