{"id":64815,"date":"2024-10-29T13:55:17","date_gmt":"2024-10-29T13:55:17","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&#038;p=64815"},"modified":"2026-05-10T08:48:12","modified_gmt":"2026-05-10T08:48:12","slug":"niclosig","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ro\/product\/niclosig\/","title":{"rendered":"Niclosig"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"margin:0 0 22px;padding:16px 20px;background:#fff8e1;border-left:4px solid #f5a623;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px;font-size:18px;color:#2c3e50;\">Quick Answer &mdash; What is Niclosig?<\/h3>\n<div style=\"margin:0;font-size:15px;line-height:1.55;color:#333;\">\n<p><strong>Niclosig<\/strong> este <strong>niclosamide 500&nbsp;mg chewable<\/strong> de la <strong>Sigmund Promedia<\/strong>. Niclosamide is the WHO Essential Medicine for <strong>intestinal tapeworm<\/strong> (Taenia saginata, Taenia solium intestinal-form, Hymenolepis nana, Diphyllobothrium latum). Standard adult dose: <strong>2&nbsp;g (4 tablets) as a single dose<\/strong>, chewed thoroughly and swallowed with a small amount of water on an empty stomach.<\/p>\n<\/div>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"margin:24px 0;padding:14px 18px;background:#f4f4f4;border:1px solid #e1e1e1;border-radius:4px;font-size:14px;color:#444;line-height:1.55;\"><strong>De ce s\u0103 comanzi de la MedsBase:<\/strong> \u2713 Provenien\u021b\u0103 de la <strong>produc\u0103tori certifica\u021bi WHO-GMP<\/strong> \u00b7 \u2713 Ambalaj discret \u00b7 \u2713 Livrare la nivel mondial \u00b7 \u2713 <strong>Peste 1.400 de recenzii ale clien\u021bilor<\/strong> la <a href=\"https:\/\/medsbase.com\/ro\/reviews\/\">medsbase.com\/reviews<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Fiecare comand\u0103 este acoperit\u0103 de politica noastr\u0103 de <a href=\"https:\/\/medsbase.com\/ro\/medsbase-re-shipment-assurance-policy\/\"><strong>Politica noastr\u0103 de Reexpediere Garantat\u0103<\/strong><\/a> \u2014 dac\u0103 coletul dumneavoastr\u0103 nu sose\u0219te \u00een 20 de zile lucr\u0103toare, \u00eel relivr\u0103m.<\/p>\n<h3>De ce s\u0103 comanzi de la MedsBase<\/h3>\n<p>Medicamentele noastre generice sunt procurate de la produc\u0103tori certifica\u021bi WHO-GMP \u0219i expediate la nivel mondial \u00een ambalaje discrete \u0219i simple \u2014 f\u0103r\u0103 denumirea medicamentului pe exteriorul coletului. Pl\u0103\u021bile cu cardul sunt procesate printr-un procesor reglementat (descrierile de pe extrasul de cont includ un procesor de pl\u0103\u021bi cu card reglementat \u2014 niciodat\u0103 \u201cMedsBase\u201d sau numele vreunui medicament). Accept\u0103m \u0219i criptomonede \u0219i transferuri bancare SEPA. Fiecare comand\u0103 este sus\u021binut\u0103 de Politica noastr\u0103 de Asigurare pentru Relivrare.<\/p>\n<h2 class=\"wp-block-heading\">What is Niclosig?<\/h2>\n<p><strong>Niclosig<\/strong> is niclosamide 500&nbsp;mg chewable from <strong>Sigmund Promedia<\/strong>. Niclosamide is a salicylanilide-class anthelmintic with a niche but irreplaceable role: it is the cleanest, most reliable single-dose treatment for <strong>intestinal cestodes<\/strong> (tapeworms). It is on the WHO Model List of Essential Medicines and has been used continuously since the 1960s.<\/p>\n<h2 class=\"wp-block-heading\">Mecanism de ac\u021biune<\/h2>\n<p>Niclosamide <strong>uncouples oxidative phosphorylation<\/strong> in the tapeworm scolex (head). This depletes parasite ATP, paralyses the scolex, and disrupts its grip on the gut wall. The worm is then partially digested by host enzymes &mdash; you may see fragmented proglottids in stool rather than an intact worm. Niclosamide is essentially not absorbed from the gut (&lt; 5%), which is therapeutically perfect: high luminal concentration, near-zero systemic exposure.<\/p>\n<h2 class=\"wp-block-heading\">Niclosig indications and dose<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:14px;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Indica\u021bie<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Doza<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Program<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Beef tapeworm (Taenia saginata)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">2&nbsp;g (4 tablets)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Single dose, chewed on empty stomach<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Pork tapeworm intestinal form (Taenia solium)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">2&nbsp;g (4 tablets)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Single dose; consider laxative 2&nbsp;h post-dose to reduce theoretical cysticercosis risk<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Fish tapeworm (Diphyllobothrium latum)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">2&nbsp;g (4 tablets)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Doza unic\u0103<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Dwarf tapeworm (Hymenolepis nana)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">2&nbsp;g day 1, then 1&nbsp;g daily &times; 6 days<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">7-day course<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>Chew the tablets thoroughly<\/strong>, then swallow with a small amount of water. Take on an empty stomach in the morning, or after a light breakfast. For Taenia solium specifically, some clinicians give a saline laxative 2&nbsp;h after the dose to evacuate dead proglottids and reduce the (rare) theoretical risk of egg release into the gut and resulting cysticercosis.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>Cysticercosis is a separate disease.<\/strong> Niclosamide treats <em>intestinal<\/em> tapeworm. <strong>Neurocisticercoz\u0103<\/strong> (Taenia solium larval cysts in the CNS) is treated with albendazole or praziquantel under specialist supervision with imaging and concomitant steroids &mdash; not with niclosamide. Headache, seizures, or focal neurological signs in a tapeworm patient need urgent imaging.<\/div>\n<h2 class=\"wp-block-heading\">Efecte secundare<\/h2>\n<ul>\n<li><strong>Frecvente:<\/strong> mild nausea, abdominal discomfort, transient diarrhoea<\/li>\n<li><strong>Mai pu\u021bin frecvente:<\/strong> headache, dizziness, mild rash<\/li>\n<li><strong>Rare:<\/strong> hypersensitivity reactions, photosensitivity<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Interac\u021biuni medicamentoase<\/h2>\n<p>Because niclosamide is essentially unabsorbed, clinically significant drug interactions are very rare. <strong>Alcool<\/strong> is best avoided on the day of dosing &mdash; it can theoretically increase niclosamide solubility and absorption, though this has no documented adverse outcome.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>Sarcina \u0219i al\u0103ptarea.<\/strong> Albendazolul \u0219i mebendazolul NU sunt recomandate \u00een primul trimestru (date de teratogenitate la animale). Utilizarea este acceptabil\u0103 \u00een trimestrul 2\/3 pentru infest\u0103ri moderate sau severe cu viermi. Datele privind ivermectina \u00een sarcin\u0103 sunt limitate, dar \u00eencurajatoare \u00een programele WHO de tratament \u00een mas\u0103; evita\u021bi \u00een primul trimestru acolo unde exist\u0103 alternative. Praziquantelul \u0219i pirantelul sunt compatibile cu sarcina.<\/div>\n<h2 class=\"wp-block-heading\">Contraindica\u021bii<\/h2>\n<ul>\n<li>Hypersensitivity to niclosamide<\/li>\n<li>Cysticercosis or neurocysticercosis &mdash; use praziquantel\/albendazole under specialist care<\/li>\n<li>Children &lt; 2 years &mdash; weight-band dosing only under medical supervision<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Depozitare<\/h2>\n<p>Store Niclosig below 30&deg;C, away from light and moisture.<\/p>\n<h3 class=\"wp-block-heading\">De ce s\u0103 comanzi de la MedsBase<\/h3>\n<p>Niclosig is supplied from a <strong>produc\u0103tor certificat WHO-GMP<\/strong>, ambalat\u0103 discret \u0219i expediat\u0103 la nivel mondial. Fiecare comand\u0103 este acoperit\u0103 de asigurarea noastr\u0103 <a href=\"https:\/\/medsbase.com\/ro\/medsbase-re-shipment-assurance-policy\/\">Politica noastr\u0103 de Reexpediere Garantat\u0103<\/a> \u2014 nu suporta\u021bi niciodat\u0103 costul unui colet pierdut.<\/p>\n<h2 id=\"faqs\">\u00centreb\u0103ri frecvente<\/h2>\n<h3 class=\"wp-block-heading\">How will I know the tapeworm is gone?<\/h3>\n<p>Confirm with stool ova-and-parasite testing 1 and 3 months after treatment. Visible passage of fragmented proglottids in stool over the days following the dose is normal. The scolex (head) may not be visible &mdash; that&rsquo;s expected because it&rsquo;s the part the drug works on first.<\/p>\n<h3 class=\"wp-block-heading\">Why chew the tablets?<\/h3>\n<p>Chewing maximises dispersion in the gut lumen where tapeworms live. Swallowing whole reduces local concentration and lowers cure rates.<\/p>\n<h3 class=\"wp-block-heading\">Should I take a laxative after?<\/h3>\n<p>Routine laxative is unnecessary for Taenia saginata or Diphyllobothrium. For Taenia solium specifically, some clinicians give a saline laxative 2&nbsp;h post-dose &mdash; this is to expel proglottids quickly and theoretically reduce the chance of egg release and resulting cysticercosis. Discuss with your clinician.<\/p>\n<h3 class=\"wp-block-heading\">Can niclosamide treat roundworm?<\/h3>\n<p>No. Niclosamide is tapeworm-specific. For roundworm, hookworm, pinworm, or whipworm use albendazole or mebendazole.<\/p>\n<h3 class=\"wp-block-heading\">Why is niclosamide preferred over praziquantel for intestinal tapeworm?<\/h3>\n<p>Both work for intestinal tapeworm. Niclosamide has near-zero systemic absorption, fewer side effects, and is cheaper. Praziquantel is the agent of choice for tissue-stage cestodes (neurocysticercosis), schistosomiasis, and most fluke infections &mdash; broader but more expensive.<\/p>\n<h3 class=\"wp-block-heading\">Is Niclosig safe in pregnancy?<\/h3>\n<p>Limited data; the lack of systemic absorption is reassuring. The first trimester is typically avoided where possible. Discuss with a clinician.<\/p>\n<h3 class=\"wp-block-heading\">Can children take Niclosig?<\/h3>\n<p>Yes from age 2 with weight-band dosing: 11&ndash;34&nbsp;kg = 1&nbsp;g (2 tablets); &gt; 34&nbsp;kg = adult dose. Below age 2, consult a paediatrician.<\/p>\n<h3 class=\"wp-block-heading\">Should I retreat?<\/h3>\n<p>Routine retreat is not standard. Confirm cure with stool testing at 1 and 3 months. If proglottids reappear or stool shows persistent infection, repeat the single dose.<\/p>\n<h3 class=\"wp-block-heading\">What about alcohol after taking Niclosig?<\/h3>\n<p>Avoid alcohol on the day of treatment &mdash; it can theoretically increase niclosamide absorption and is associated with rare reports of nausea and flushing.<\/p>\n<h3 class=\"wp-block-heading\">Can I take other medicines with Niclosig?<\/h3>\n<p>Yes. Because niclosamide is essentially unabsorbed, clinically significant drug interactions are very rare. Standard chronic medications can continue uninterrupted.<\/p>\n<p class=\"medsbase-link-boost-2026-05-10\" data-marker=\"mb-link-boost-iverheal\">When a patient treated with <a href=\"https:\/\/medsbase.com\/ro\/niclosig\/\">Niclosig (niclosamide 500 mg)<\/a> for intestinal tapeworms also presents with scabies or strongyloidiasis, practitioners typically add a separate ivermectin course such as <a href=\"https:\/\/medsbase.com\/ro\/iverheal\/\">Iverheal (ivermectin 3 \/ 6 \/ 12 mg)<\/a> to address the ectoparasitic component.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Alte Medicamente Antiparazitare<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/ro\/niclosig\/\">Niclosig (niclosamide 500 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ro\/prazinec\/\">Prazinec (praziquantel 600 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ro\/abd-400-albendazole\/\">ABD 400 (albendazol 400 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ro\/mebex\/\">Mebex (mebendazole)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ro\/tinvista\/\">Tinvista (tinidazole)<\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:22px 0;border-radius:4px;font-size:14px;color:#444;\"><strong>Not\u0103 medical\u0103.<\/strong> Aceast\u0103 pagin\u0103 are scop strict informativ \u0219i nu \u00eenlocuie\u0219te sfatul medical profesionist. Consulta\u021bi un clinician calificat \u00eenainte de a \u00eencepe orice tratament antihelmintic, \u00een special dac\u0103 sunte\u021bi gravid\u0103 sau al\u0103pta\u021bi, imunosupres, trata\u021bi un copil sub 2 ani sau dac\u0103 simptomele persist\u0103 dup\u0103 un curs de tratament. Eozinofilia, pierderea \u00een greutate, dureri abdominale persistente sau simptome legate de c\u0103l\u0103torii necesit\u0103 evaluare clinic\u0103. Bolile parazitare severe (neurocisticercoz\u0103, hiperinfec\u021bie cu strongiloizi, schistosomiaza cu afectare organic\u0103) necesit\u0103 management specializat.<\/div>","protected":false},"excerpt":{"rendered":"<p>Niclosig (niclosamide 500 mg chewable) \u2014 tapeworm-specific anthelmintic for Taenia saginata, Taenia solium intestinal, Diphyllobothrium latum, and Hymenolepis nana. Single 2-g chewed dose.<\/p>","protected":false},"featured_media":64816,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3856],"product_tag":[5321,5320],"class_list":{"0":"post-64815","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-threadworm-treatment","7":"product_tag-niclosamide","8":"product_tag-niclosig","10":"first","11":"instock","12":"shipping-taxable","13":"purchasable","14":"product-type-variable","15":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product\/64815","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/comments?post=64815"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/media\/64816"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/media?parent=64815"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product_brand?post=64815"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product_cat?post=64815"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product_tag?post=64815"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}