{"id":69005,"date":"2026-03-13T11:51:26","date_gmt":"2026-03-13T11:51:26","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&p=69005"},"modified":"2026-05-21T07:14:11","modified_gmt":"2026-05-21T07:14:11","slug":"cjc-1295-without-dac","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ro\/product\/cjc-1295-without-dac\/","title":{"rendered":"CJC-1295 f\u0103r\u0103 DAC"},"content":{"rendered":"

<\/p>\n

\n

Quick Answer \u2014 What is CJC-1295 without DAC?<\/h3>\n

CJC-1295 f\u0103r\u0103 DAC<\/strong> (also called Mod GRF 1-29<\/strong>) is a synthetic modified GHRH (1-29) analog with a short ~30-minute plasma half-life. Unlike the DAC version, it lacks the albumin-binding tether, producing a pulsatile<\/strong> rather than sustained GH signal. This kinetic profile makes it the preferred research tool when pulse-timing matters. Supplied in 2\u00a0mg to 10\u00a0mg lyophilized vials for laboratory research use only.<\/p>\n<\/div>\n

Ce beneficii ofer\u0103 MedsBase:<\/strong> Peptide liofilizate pentru cercetare \u00b7 puritate HPLC \u226599% (certificat de analiz\u0103 la cerere) \u00b7 Ambalaj discret stabil la temperatur\u0103 \u00b7 Curierat worldwide de peptide \u00b7 Peste 1.400 de recenzii verificate ale clien\u021bilor<\/a><\/div>\n

\ud83d\udce6 Fiecare comand\u0103 este acoperit\u0103 de politica noastr\u0103 de Politica noastr\u0103 de Reexpediere Garantat\u0103<\/strong><\/a> \u2014 dac\u0103 coletul dumneavoastr\u0103 nu sose\u0219te \u00een 20 de zile lucr\u0103toare, \u00eel relivr\u0103m.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Specifica\u021bii<\/th>\nDetaliu<\/th>\n<\/tr>\n<\/thead>\n
Num\u0103r CAS<\/strong><\/td>\n863288-34-0 (parent) \u00b7 446262-90-4 (Mod-GRF 1\u201329 form widely cited)<\/td>\n<\/tr>\n
Formula molecular\u0103<\/strong><\/td>\nC152<\/sub>H252<\/sub>N44<\/sub>O42<\/sub><\/td>\n<\/tr>\n
Greutate molecular\u0103<\/strong><\/td>\n3367.92 Da<\/td>\n<\/tr>\n
Secven\u021b\u0103<\/strong><\/td>\nD-Ala-Tyr-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2<\/sub> (Mod-GRF 1\u201329, no DAC linker)<\/td>\n<\/tr>\n
Form\u0103<\/strong><\/td>\nPulbere liofilizat\u0103 (sau a\u0219a cum este furnizat)<\/td>\n<\/tr>\n
Puritate<\/strong><\/td>\n\u226599% (verificat prin HPLC, COA la cerere)<\/td>\n<\/tr>\n
Depozitare<\/strong><\/td>\nLiofilizat: 2\u20138\u00b0C (frigider) pentru stocul de lucru; \u221220\u00b0C pentru depozitarea pe termen lung a vialelor nefolosite. Reconstituit: 2\u20138\u00b0C, utilizat \u00een ~30 de zile. Proteja\u021bi de lumin\u0103. Nu \u00eenghe\u021ba\u021bi-decongela\u021bi solu\u021bia reconstituit\u0103.<\/td>\n<\/tr>\n
Solubilitate<\/strong><\/td>\nAp\u0103 bacteriostatic\u0103 (recomandat\u0103) sau ap\u0103 steril\u0103 pentru perioade mai scurte de utilizare<\/td>\n<\/tr>\n
Utilizare \u00een cercetare<\/strong><\/td>\nDoar pentru utilizare \u00een cercetare de laborator. Nu este destinat pentru uz diagnostic sau terapeutic uman sau veterinar.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

<\/p>\n

What Is CJC-1295 without DAC?<\/h2>\n

CJC-1295 f\u0103r\u0103 DAC<\/strong> (commonly called Mod GRF 1-29<\/strong> or simply tetrasubstituted GRF 1-29<\/strong>) is a synthetic 30-amino-acid analog of growth-hormone-releasing hormone. It shares the same core peptide sequence as CJC-1295 cu DAC<\/a> \u2014 four amino-acid substitutions on the native GHRH (1-29) sequence provide resistance to DPP-IV cleavage \u2014 but lacks the albumin-binding DAC modification<\/strong> that extends half-life in the “with DAC” version.<\/p>\n

The practical consequence of no DAC: plasma half-life remains in the minutes-to-hours range (~30 minutes) rather than days. Research protocols therefore use multiple daily injections (typically 2\u20133x) to maintain GHRH signal rather than the weekly dosing of the DAC version. This mimics the short, pulsatile profile of endogenous GHRH and is the preferred research tool when pulse-timing matters \u2014 particularly in protocols studying physiological GH pulsatility alongside ghrelin-receptor agonists such as ipamorelin<\/a>.<\/p>\n

Molecular weight approximately 3,367\u00a0Da. Supplied as a high-purity lyophilized powder for reconstitution with bacteriostatic water. CJC-1295 without DAC is destinat doar pentru cercetare de laborator<\/strong> and is not intended for human or veterinary diagnosis or therapy. For mechanism, research context, and stacking protocols, see our Ipamorelin & CJC-1295 research guide<\/a>.<\/p>\n

Mechanism of Action \u2014 Pulsatile GHRH Signaling<\/h2>\n

Mod GRF 1-29 acts through the same pituitary GHRH receptor pathway as native GHRH, but with a kinetic profile that distinguishes it from both native GHRH and the DAC version:<\/p>\n