{"id":69013,"date":"2026-03-13T11:58:53","date_gmt":"2026-03-13T11:58:53","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&p=69013"},"modified":"2026-05-21T07:14:11","modified_gmt":"2026-05-21T07:14:11","slug":"kpv-lysine-proline-valine","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ro\/product\/kpv-lysine-proline-valine\/","title":{"rendered":"KPV (Lizin\u0103-Prolin\u0103-Valin\u0103)"},"content":{"rendered":"

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Quick Answer \u2014 What is KPV?<\/h3>\n

KPV<\/strong> is the Lys-Pro-Val tripeptide \u2014 the C-terminal anti-inflammatory fragment of alpha-melanocyte stimulating hormone (\u03b1-MSH). Unlike broader melanocortin analogs, KPV has no pigmentation activity<\/strong>; its research signal is purely anti-inflammatory via NFkB inhibition and mast-cell stabilization. Studied for IBD, allergic inflammation, and skin-inflammation research. Supplied in 5\u00a0mg and 10\u00a0mg lyophilized vials for laboratory research use only.<\/p>\n<\/div>\n

Ce beneficii ofer\u0103 MedsBase:<\/strong> Peptide liofilizate pentru cercetare \u00b7 puritate HPLC \u226599% (certificat de analiz\u0103 la cerere) \u00b7 Ambalaj discret stabil la temperatur\u0103 \u00b7 Curierat worldwide de peptide \u00b7 Peste 1.400 de recenzii verificate ale clien\u021bilor<\/a><\/div>\n

\ud83d\udce6 Fiecare comand\u0103 este acoperit\u0103 de politica noastr\u0103 de Politica noastr\u0103 de Reexpediere Garantat\u0103<\/strong><\/a> \u2014 dac\u0103 coletul dumneavoastr\u0103 nu sose\u0219te \u00een 20 de zile lucr\u0103toare, \u00eel relivr\u0103m.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Specifica\u021bii<\/th>\nDetaliu<\/th>\n<\/tr>\n<\/thead>\n
Num\u0103r CAS<\/strong><\/td>\n67727-97-3<\/td>\n<\/tr>\n
Formula molecular\u0103<\/strong><\/td>\nC16<\/sub>H30<\/sub>N4<\/sub>O4<\/sub><\/td>\n<\/tr>\n
Greutate molecular\u0103<\/strong><\/td>\n342.43 Da<\/td>\n<\/tr>\n
Secven\u021b\u0103<\/strong><\/td>\nLys-Pro-Val (\u03b1-MSH 11\u201313)<\/td>\n<\/tr>\n
Form\u0103<\/strong><\/td>\nPulbere liofilizat\u0103 (sau a\u0219a cum este furnizat)<\/td>\n<\/tr>\n
Puritate<\/strong><\/td>\n\u226599% (verificat prin HPLC, COA la cerere)<\/td>\n<\/tr>\n
Depozitare<\/strong><\/td>\nLiofilizat: 2\u20138\u00b0C (frigider) pentru stocul de lucru; \u221220\u00b0C pentru depozitarea pe termen lung a vialelor nefolosite. Reconstituit: 2\u20138\u00b0C, utilizat \u00een ~30 de zile. Proteja\u021bi de lumin\u0103. Nu \u00eenghe\u021ba\u021bi-decongela\u021bi solu\u021bia reconstituit\u0103.<\/td>\n<\/tr>\n
Solubilitate<\/strong><\/td>\nAp\u0103 bacteriostatic\u0103 (recomandat\u0103) sau ap\u0103 steril\u0103 pentru perioade mai scurte de utilizare<\/td>\n<\/tr>\n
Utilizare \u00een cercetare<\/strong><\/td>\nDoar pentru utilizare \u00een cercetare de laborator. Nu este destinat pentru uz diagnostic sau terapeutic uman sau veterinar.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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What Is KPV?<\/h2>\n

KPV<\/strong> is the three-letter one-letter-code shorthand for the Lys-Pro-Val tripeptide<\/strong> \u2014 the C-terminal three amino acids (positions 11\u201313) of alpha-melanocyte stimulating hormone (\u03b1-MSH). In the 1980s\u20131990s, multiple research groups noticed that the full \u03b1-MSH molecule produced two functionally separable effects: the well-known N-terminal MC-receptor pigmentation\/arousal activity, and a C-terminal antiinflamatoare<\/strong> activity. When the C-terminal KPV tripeptide was synthesised and tested in isolation, it reproduced the anti-inflammatory effects without the pigmentation side-effects.<\/p>\n

Molecular weight approximately 342.4\u00a0Da. KPV is one of the smallest peptides in the melanocortin family and one of the most-studied anti-inflammatory research tripeptides. It is supplied as a high-purity lyophilized powder. KPV is destinat doar pentru cercetare de laborator<\/strong> and is not intended for human or veterinary diagnosis or therapy. For mechanism, IBD research history, and stacking context, see our KPV research guide<\/a>.<\/p>\n

Mechanism of Action \u2014 Three Anti-Inflammatory Pathways<\/h2>\n

KPV’s anti-inflammatory activity operates through at least three complementary pathways, all of which converge on reducing inflammatory signaling without affecting other melanocortin functions:<\/p>\n