{"id":3565,"count":7,"description":"Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder affecting 5\u201310% of adults, characterised by abdominal pain associated with altered bowel habit. Inflammatory bowel disease (IBD \u2014 ulcerative colitis and Crohn's disease) is a distinct group of immune-mediated chronic inflammatory conditions affecting younger adults disproportionately. The MedsBase IBS Treatment catalogue groups medications for both. Not\u0103:<\/strong> the category name historically said \"IBS\" but most products are IBD-specific (mesalamine, sulfasalazine) \u2014 we are reorganising. All products are supplied by produc\u0103tori certifica\u021bi WHO-GMP<\/strong>.\n\n5-ASA\/mesalamin\u0103 \u2014 pentru men\u021binerea colitei ulceroase \u0219i pentru puseuri u\u0219oare-moderate.<\/strong> Mesalamina oral\u0103 (acid 5-aminosalicilic) este tratamentul de baz\u0103 pentru men\u021binerea colitei ulceroase \u0219i eficient\u0103 pentru puseuri u\u0219oare-moderate. Diferitele m\u0103rci difer\u0103 prin modelul de eliberare (eliberare controlat\u0103 pH-dependent\u0103, dependent\u0103 de timp, sistem multi-matrix) care determin\u0103 locul din intestin unde este eliberat principiul activ \u2014 alegerea m\u0103rcii trebuie adaptat\u0103 distribu\u021biei bolii. Disponibile ca Mesacol<\/a>, Mesacol OD<\/a> (eliberare controlat\u0103 o dat\u0103 pe zi pentru afec\u021biuni distale), \u0219i Asacol<\/a> (c\u00e2nd este \u00een stoc). Mesalamina topic\u0103 (supozitoare, spum\u0103) pentru proctita distal\u0103 sunt listate \u00een categoria noastr\u0103 S\u0103n\u0103tate Gastrointestinal\u0103 sub denumirea Supozitoare Pentasa.\n\nSulfasalazina \u2014 pentru BII \u0219i artrita reumatoid\u0103.<\/strong> Sulfasalazina combin\u0103 5-ASA cu sulfapiridina (un purt\u0103tor de leg\u0103tur\u0103 azoic\u0103 care elibereaz\u0103 5-ASA \u00een colon). Doza standard pentru colita ulceroas\u0103 este de 2\u20134 g pe zi, administrate \u00een doze divizate. Stocat\u0103 ca Sazo<\/a> \u0219i Salazar<\/a>. Mesalamina, cu un profil de efecte adverse mai redus, este de obicei preferat\u0103 pentru BCI; sulfasalazina r\u0103m\u00e2ne util\u0103 acolo unde coexist\u0103 artropatie asociat\u0103 BCI sau artrit\u0103 reumatoid\u0103 (componenta sulfapiridin\u0103 are activitate DMARD).\n\nMebeverina \u2014 antispasmodic pentru SII.<\/strong> Mebeverina (un antispasmodic al mu\u0219chilor netezi) este de prim\u0103 inten\u021bie pentru SII predominant \u00een crampe \u0219i spasme \u2014 luat\u0103 cu 20 de minute \u00eenainte de mese. Stocat\u0103 ca Colospa<\/a>. Profilul de efecte adverse este favorabil; baza de dovezi este modest\u0103, provenind din studii mai vechi.\n\nRifaximina \u2014 pentru SII-D \u0219i SIBO.<\/strong> Rifaximina este un antibiotic luminal neabsorbat, aprobat de FDA pentru SII-D \u0219i cu utilizare mai larg\u0103 \u00een supracrescerea bacterian\u0103 a intestinului sub\u021bire (SIBO) \u0219i encefalopatia hepatic\u0103. Tratamentul const\u0103 \u00een 550 mg de trei ori pe zi timp de 2 s\u0103pt\u0103m\u00e2ni; \u00eembun\u0103t\u0103\u021birea simptomelor persist\u0103 luni de zile la mul\u021bi pacien\u021bi care r\u0103spund. Stocat\u0103 ca Rifagut<\/a>.\n\nWhat's NOT here.<\/strong> Biologic therapy (infliximab, adalimumab, vedolizumab, ustekinumab, tofacitinib) for moderate-severe IBD requires specialist initiation and monitoring \u2014 not stocked. Corticosteroids for IBD flares: oral budesonide for ileal Crohn's and right-sided UC is in our Gastro Health category as Budez CR; systemic prednisolone is in Pain Relief Medication.\n\nCum s\u0103 alegi.<\/strong> Mild-moderate ulcerative colitis \u2192 oral mesalamine first-line + topical 5-ASA for distal disease + check adherence. Mild-moderate Crohn's \u2192 mesalamine has limited evidence (works in colonic disease only); budesonide for ileal disease. IBS-C (constipation-predominant) \u2192 osmotic \/ stimulant laxatives (see Constipation Medicine category) \u00b1 linaclotide \/ lubiprostone where available. IBS-D (diarrhoea-predominant) \u2192 rifaximin 2-week course; consider eluxadoline. IBS-M (mixed) \u2192 antispasmodic (mebeverine) + lifestyle \/ FODMAP diet trial. Refractory or alarm features (weight loss, blood, anaemia, age > 50, family history of IBD or CRC) \u2192 urgent gastroenterology referral.\n\nImportant.<\/strong> IBD flares require tighter management than IBS (significant disease can be silent on standard therapy, and untreated flares progress to complications including stricture, fistula, dysplasia, and need for colectomy). Annual review with calprotectin \/ endoscopy as appropriate. Pregnancy: most 5-ASAs and sulfasalazine are continued through pregnancy; folic acid supplementation needed for sulfasalazine. Methotrexate and many biologics carry pregnancy restrictions. New diarrhoea in IBD or worsening symptoms can be C. difficile \u2014 test before assuming flare.\n\nAll MedsBase IBS Treatment products ship from produc\u0103tori certifica\u021bi WHO-GMP<\/strong> cu ambalaj discret \u0219i sunt acoperite de Politica noastr\u0103 de Reexpediere Garantat\u0103<\/a>.\n\nGhidul cump\u0103r\u0103torului 2026:<\/strong> Vede\u021bi lista noastr\u0103 scurt\u0103 Cele mai bune tratamente pentru IBS & IBD 2026<\/a> pentru alegeri clasate, tabel comparativ, note de dozare \u0219i scurt\u0103tur\u0103 de decizie.","link":"https:\/\/medsbase.com\/ro\/irritable-bowel-syndrome-ibs-treatment\/","name":"Tratament pentru sindromul intestinului iritabil (IBS)","slug":"irritable-bowel-syndrome-ibs-treatment","taxonomy":"product_cat","parent":3223,"meta":[],"menu_order":0,"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product_cat\/3565","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product_cat"}],"about":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/taxonomies\/product_cat"}],"up":[{"embeddable":true,"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product_cat\/3223"}],"wp:post_type":[{"href":"https:\/\/medsbase.com\/ro\/wp-json\/wp\/v2\/product?product_cat=3565"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}