{"id":54309,"date":"2023-09-20T09:57:09","date_gmt":"2023-09-20T09:57:09","guid":{"rendered":"https:\/\/medsname.com\/bambudil\/"},"modified":"2026-04-30T14:22:10","modified_gmt":"2026-04-30T14:22:10","slug":"bambudil","status":"publish","type":"product","link":"https:\/\/medsbase.com\/bambudil\/","title":{"rendered":"Bambudil"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 28px 0;border-radius:4px;\">\n<h3 style=\"margin:0 0 10px 0;font-size:18px;color:#1a1a1a;\">\u26a1 Quick Answer \u2014 What is Bambudil?<\/h3>\n<p><strong>Bambudil<\/strong> contains <strong>bambuterol<\/strong>, a <strong>long-acting prodrug of terbutaline<\/strong> taken as a once-daily evening tablet for asthma and COPD. Bambuterol is slowly hydrolysed by plasma cholinesterase to release active terbutaline (a \u03b22 agonist) over 24 hours \u2014 providing sustained bronchodilation without the multiple-daily dosing of short-acting agents. Used as add-on bronchodilator therapy alongside an inhaled corticosteroid in patients who prefer oral over inhaled therapy or have difficulty with inhaler technique. Each tablet contains <strong>10 mg<\/strong>, manufactured by <strong>Cipla<\/strong>.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>What you get with MedsBase:<\/strong> WHO-GMP certified manufacturer \u00b7 Discreet packaging \u00b7 Worldwide shipping \u00b7 1,400+ verified <a href=\"https:\/\/medsbase.com\/reviews\/\">customer reviews<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Every order is covered by our <a href=\"https:\/\/medsbase.com\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 if your parcel does not arrive within 20 business days, we reship it.<\/p>\n<h3>Why order from MedsBase<\/h3>\n<p>Our generic medications are sourced from WHO-GMP certified manufacturers and shipped worldwide in discreet, plain packaging \u2014 no medication name on the parcel exterior. Card payments are routed through a regulated processor (statement descriptors include a regulated card-payment processor \u2014 never &ldquo;MedsBase&rdquo; or any medication name). Crypto and SEPA bank transfer are also accepted. Every order is backed by our Reshipment Assurance Policy.<\/p>\n<div style=\"background:#f4f8fb;border:1px solid #e0e0e0;padding:12px 18px;margin:0 0 24px 0;border-radius:4px;font-size:14px;text-align:center;\">\n<strong>\ud83d\udd12 Encrypted Checkout<\/strong> \u00b7 <strong>\ud83d\udcb3 Verified Processor<\/strong> \u00b7 <strong>\ud83d\ude9a Worldwide Shipping<\/strong> \u00b7 <strong>\u2b50 4.9\/5 from 1,400+ customers<\/strong>\n<\/div>\n<h2>What Is Bambudil?<\/h2>\n<p>Bambudil contains bambuterol \u2014 a bis-dimethylcarbamate ester prodrug of terbutaline. The carbamate structure is hydrolysed slowly by butyrylcholinesterase (plasma pseudocholinesterase) to release active terbutaline gradually over 24 hours, achieving once-daily oral \u03b22-agonism. Internationally sold as Bambec (AstraZeneca) and Oxeol.<\/p>\n<h2>How Does Bambudil Work?<\/h2>\n<ul>\n<li><strong>Slow hydrolysis<\/strong> by plasma butyrylcholinesterase converts bambuterol to active terbutaline.<\/li>\n<li><strong>Terbutaline<\/strong> activates bronchial \u03b22-adrenergic receptors, raising cyclic AMP and producing sustained bronchodilation.<\/li>\n<li><strong>24-hour duration<\/strong> from a single evening dose \u2014 useful for nocturnal symptoms.<\/li>\n<li><strong>Less dependent on patient inhaler technique<\/strong> than inhaled \u03b22 agonists \u2014 a benefit for elderly or coordination-impaired patients.<\/li>\n<\/ul>\n<h2>Uses and Indications<\/h2>\n<ul>\n<li><strong>Persistent asthma<\/strong> \u2014 add-on bronchodilator alongside ICS, especially when nocturnal symptoms predominate<\/li>\n<li><strong>COPD with reversible component<\/strong> \u2014 adjunct bronchodilator<\/li>\n<li><strong>Patients who cannot use inhalers reliably<\/strong> \u2014 elderly, severe arthritis, cognitive impairment<\/li>\n<li><strong>Nocturnal asthma<\/strong> \u2014 once-daily evening dose covers overnight period<\/li>\n<\/ul>\n<h2>Bambudil Dosage<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Patient<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Dose<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Frequency<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Adults \u2014 initial<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>10 mg<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Once daily in the evening<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Adults \u2014 maintenance<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>10\u201320 mg<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Once daily in the evening<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Children &gt;6 yr<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>10 mg<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Once daily \u2014 specialist supervision<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Hepatic impairment \/ pseudocholinesterase deficiency<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Reduce dose 50%<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Once daily<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Side Effects of Bambudil<\/h2>\n<ul>\n<li>Fine tremor (\u03b22 effect)<\/li>\n<li>Palpitations, mild tachycardia<\/li>\n<li>Headache<\/li>\n<li>Muscle cramps<\/li>\n<li>Hypokalaemia at high doses (with diuretics, theophylline, oral steroids)<\/li>\n<li>Insomnia (less common with evening dosing)<\/li>\n<\/ul>\n<p><strong>Serious \u2014 stop and seek help:<\/strong><\/p>\n<ul>\n<li>Severe palpitations or arrhythmia<\/li>\n<li>Severe allergic reaction<\/li>\n<li>Paradoxical bronchospasm<\/li>\n<\/ul>\n<h2>Warnings and Precautions<\/h2>\n<ul>\n<li><strong>{$brand} is a controller, not a reliever.<\/strong> Keep a SABA for acute attacks.<\/li>\n<li><strong>Cardiovascular disease:<\/strong> caution with arrhythmias, severe coronary artery disease, hyperthyroidism.<\/li>\n<li><strong>Pseudocholinesterase deficiency<\/strong> \u2014 reduces hydrolysis; bambuterol accumulates and effect prolongs. Halve dose.<\/li>\n<li><strong>Drug interaction with cholinesterase inhibitors<\/strong> (donepezil, rivastigmine, pyridostigmine, suxamethonium) \u2014 bambuterol prolongs their action; suxamethonium-induced apnoea has been reported.<\/li>\n<li><strong>Pregnancy and breastfeeding:<\/strong> limited data; inhaled \u03b22-agonists are first-line.<\/li>\n<\/ul>\n<h2>Contraindications<\/h2>\n<ul>\n<li>Hypersensitivity to bambuterol or terbutaline<\/li>\n<li>Severe hepatic impairment<\/li>\n<li>Concurrent suxamethonium (depolarising muscle relaxant) \u2014 relative; warn anaesthetist<\/li>\n<\/ul>\n<h2>Drug Interactions<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Interacting drug<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Effect<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">What to do<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Non-selective beta-blockers (propranolol, timolol drops)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Block \u03b22 effect \u2014 can precipitate severe bronchospasm<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Avoid; switch to cardioselective beta-blocker if essential<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Loop or thiazide diuretics<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Additive hypokalaemia<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor serum potassium with high doses<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Systemic corticosteroids<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Additive hypokalaemia + hyperglycaemia<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor electrolytes and glucose<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Theophylline \/ aminophylline<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Additive tachycardia and hypokalaemia<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor heart rate and potassium<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">MAOIs and tricyclic antidepressants<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Potentiate cardiovascular effects<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Caution \u2014 monitor BP\/HR<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Digoxin<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Hypokalaemia increases digoxin toxicity risk<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor potassium; check digoxin level if symptomatic<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Storage<\/h2>\n<ul>\n<li>Store below <strong>25\u00b0C<\/strong> in a cool, dry place away from direct sunlight.<\/li>\n<li>Keep in original packaging until use to protect from moisture and light.<\/li>\n<li>Do not use after the expiry date printed on the strip.<\/li>\n<li>Keep out of reach of children.<\/li>\n<\/ul>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2>Related Alternatives on MedsBase<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/asthalin-inhaler\/\"><strong>Asthalin Inhaler \u2014 salbutamol reliever<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/budecort-inhaler\/\"><strong>Budecort Inhaler \u2014 budesonide ICS preventer<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/foracort-inhaler\/\"><strong>Foracort Inhaler \u2014 budesonide + formoterol ICS-LABA<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/tiova-inhaler\/\"><strong>Tiova Inhaler \u2014 tiotropium LAMA for COPD<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/montair\/\"><strong>Montair \u2014 montelukast LTRA tablet<\/strong><\/a><\/li>\n<\/ul>\n<h2 id=\"faqs\">Frequently Asked Questions<\/h2>\n<h3>How is Bambudil different from salbutamol or terbutaline tablets?<\/h3>\n<p>Bambudil contains bambuterol \u2014 a slow-release prodrug of terbutaline. It provides 24-hour bronchodilation from a single evening dose. Standard terbutaline or salbutamol tablets last 4\u20136 hours and require 3\u20134 daily doses.<\/p>\n<h3>When is Bambudil useful?<\/h3>\n<p>For nocturnal asthma (overnight cover from evening dose), for patients who cannot reliably use inhalers (elderly, severe arthritis, cognitive impairment), or as add-on long-acting \u03b22 agonism alongside ICS.<\/p>\n<h3>Is Bambudil a reliever?<\/h3>\n<p>No \u2014 slow onset (~2 hours to peak). Keep a SABA (Asthalin, Levolin) for acute attacks.<\/p>\n<h3>Can I take it during the day instead of evening?<\/h3>\n<p>Evening dosing is recommended \u2014 covers the overnight period when nocturnal asthma symptoms are common, and timing the side effects (mild tremor) when you are sleeping.<\/p>\n<h3>Why warn the anaesthetist?<\/h3>\n<p>Bambuterol inhibits plasma butyrylcholinesterase. Suxamethonium (a depolarising muscle relaxant used in anaesthesia) is broken down by the same enzyme \u2014 combination can prolong suxamethonium-induced apnoea. Tell any anaesthetist before surgery.<\/p>\n<h3>Is Bambudil safe in pregnancy?<\/h3>\n<p>Limited data; inhaled \u03b22 agonists are first-line.<\/p>\n<h3>Can I take Bambudil with my ICS?<\/h3>\n<p>Yes \u2014 typically used as oral add-on to ICS (Budecort, Beclate). Modern practice prefers inhaled ICS-LABA combinations (Foracort, Seretide), but oral bambuterol remains useful when inhaler use is impractical.<\/p>\n<h3>How fast does Bambudil work?<\/h3>\n<p>Onset begins around 2 hours after dose; sustained bronchodilation over 24 hours.<\/p>\n<h3>Is Bambudil habit-forming?<\/h3>\n<p>No \u2014 no dependence or tolerance. Frequent need for additional reliever indicates poor asthma control, not addiction.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:24px 0;border-radius:4px;font-size:13px;\"><strong>Medical disclaimer:<\/strong> This page is educational and does not replace professional medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any inhaler or respiratory medication, especially if you have other medical conditions, take other prescriptions, are pregnant or breastfeeding, or are over 65.<\/div>\n","protected":false},"excerpt":{"rendered":"<h5>\u2705 Effective bronchodilation<br \/>\n\u2705 Rapid symptom relief<br \/>\n\u2705 Convenient tablet format<br \/>\n\u2705 Enhanced respiratory comfort<\/h5>\n<p><span style=\"color: #999999;\">Contains Bambuterol<\/span><\/p>\n","protected":false},"featured_media":54310,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3681,3141,3223],"product_tag":[3706,3707],"class_list":{"0":"post-54309","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-asthma-copd-treatment","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","9":"product_tag-bambudil","10":"product_tag-bambuterol","12":"first","13":"outofstock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product\/54309","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/comments?post=54309"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/media\/54310"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/media?parent=54309"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product_brand?post=54309"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product_cat?post=54309"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product_tag?post=54309"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}