{"id":57121,"date":"2024-02-27T17:24:45","date_gmt":"2024-02-27T17:24:45","guid":{"rendered":"https:\/\/medsname.com\/flunil\/"},"modified":"2026-04-30T10:24:31","modified_gmt":"2026-04-30T10:24:31","slug":"flunil","status":"publish","type":"product","link":"https:\/\/medsbase.com\/sv\/product\/flunil\/","title":{"rendered":"Flunil"},"content":{"rendered":"

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\u26a1 Snabbt svar<\/h3>\n

Flunil (Fluoxetine 10 \/ 20 \/ 40 \/ 60 mg) is a selective serotonin reuptake inhibitor used for depression, anxiety, and related disorders. Long half-life (4\u201316 days) means slow onset and gentle self-taper.<\/p>\n<\/div>\n

\nVad du f\u00e5r med MedsBase:<\/strong> WHO-GMP-certifierad tillverkare \u00b7 Diskret f\u00f6rpackning \u00b7 V\u00e4rldsvid leverans \u00b7 1 400+ verifierade kundrecensioner<\/a>\n<\/div>\n

\ud83d\udce6 Varje best\u00e4llning omfattas av v\u00e5r Reshipment Assurance Policy<\/strong><\/a> \u2014 om din f\u00f6rs\u00e4ndelse inte anl\u00e4nder inom 20 arbetsdagar, skickar vi om den.<\/p>\n

Varf\u00f6r best\u00e4lla fr\u00e5n MedsBase<\/h3>\n

Flunil at MedsBase is supplied directly from a WHO-GMP certified manufacturer in plain, discreet packaging. Every order is covered by our Reshipment Assurance Policy<\/a> \u2014 20 arbetsdagar leveranstid eller vi skickar om utan extra kostnad \u2014 och kvalificerar sig f\u00f6r v\u00e5rt kundlojalitetsprogram<\/a>. V\u00e4rldsomsp\u00e4nnande leverans \u00e4r tillg\u00e4nglig till de flesta destinationer.<\/p>\n

How Flunil works<\/h2>\n

Flunil<\/strong> is a Fluoxetine-containing SSRI tablet supplied by Intas. Available strengths: 10 \/ 20 \/ 40 \/ 60 mg<\/strong>. Ta med eller utan mat, vid samma tidpunkt varje dag f\u00f6r stabila plasmaniv\u00e5er.<\/p>\n

SSRI-preparat blockerar \u00e5terupptaget av serotonin (5-HT) vid den presynaptiska serotonintransport\u00f6ren (SERT), vilket \u00f6kar tillg\u00e4ngligheten av serotonin i synapsen. Den terapeutiska effekten upptr\u00e4der 2\u20136 veckor efter transporterblockaden \u2014 f\u00f6rdr\u00f6jningen speglar anpassningar i k\u00e4nsligheten hos 5-HT-autoreceptorer, BDNF-uttryck och neurogenes i hippocampus, inte direkta receptorp\u00e5verkan. Patienter som inte k\u00e4nner n\u00e5gon effekt efter 2 veckor b\u00f6r inte avbryta behandlingen; utv\u00e4rdera effekten efter 4\u20136 veckor vid adekvat dosering.<\/p>\n

Of all SSRIs, fluoxetine is the most activating<\/strong> \u2014 useful when fatigue and anergic depression are the dominant symptoms, problematic when anxiety and insomnia are dominant. Take in the morning. Adolescent MDD is one of fluoxetine’s strongest evidence bases (TADS trial).<\/p>\n

Indikationer och dosering<\/h2>\n\n\n\n\n\n\n\n\n\n
Indikation<\/th>\nStartdos<\/th>\nM\u00e5lgrupp<\/th>\nAnteckningar<\/th>\n<\/tr>\n<\/thead>\n
Major depression (adult)<\/td>\n20 mg OD morning<\/td>\n20\u201360 mg OD<\/td>\nMax 80 mg<\/td>\n<\/tr>\n
OCD<\/td>\n20 mg OD \u00d7 2 wk<\/td>\n40\u201380 mg OD<\/td>\nSlow up-titration<\/td>\n<\/tr>\n
Bulimia nervosa<\/td>\n20 mg OD \u00d7 1 wk<\/td>\n60 mg OD<\/td>\nMost-used SSRI for BN<\/td>\n<\/tr>\n
PMDD (continuous or luteal)<\/td>\n20 mg en g\u00e5ng dagligen<\/td>\n20 mg en g\u00e5ng dagligen<\/td>\nCycles 1\u201314 only if luteal<\/td>\n<\/tr>\n
Adolescent MDD (\u22658 y)<\/td>\n10 mg en g\u00e5ng dagligen \u00d7 1 v<\/td>\n20 mg en g\u00e5ng dagligen<\/td>\nFDA-approved <18<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Viktiga s\u00e4kerhets\u00f6verv\u00e4ganden<\/h2>\n
\nLong half-life \u2014 slow on, slow off<\/strong><\/p>\n

Fluoxetine + active metabolite norfluoxetine have a combined elimination half-life of 4\u201316 days<\/strong>. This means: (1) discontinuation syndrome is rare even on abrupt stop \u2014 the drug self-tapers; (2) dose increases take 4\u20136 weeks to reach steady state; (3) when switching to another antidepressant, allow a 5-week washout before starting an MAOI to avoid serotonin syndrome.<\/p>\n<\/div>\n

\nSj\u00e4lvmordstankar black-box (under 25)<\/strong><\/p>\n

Alla SSRI-preparat b\u00e4r en FDA svart l\u00e5da-varning f\u00f6r \u00f6kad suicidal tankeverksamhet hos patienter under 25 \u00e5r, s\u00e4rskilt under de f\u00f6rsta 4 veckorna och vid dos\u00e4ndringar. Detta betyder inte<\/em> inte att SSRI-preparat \u00e4r netto-skadliga f\u00f6r unga m\u00e4nniskor \u2014 metaanalyser visar netto-f\u00f6rdel \u2014 men det betyder att klinisk \u00f6vervakning kr\u00e4vs under inledning och titrering hos ton\u00e5ringar och unga vuxna.<\/p>\n<\/div>\n

\nSerotoninsyndrom<\/strong><\/p>\n

Combining Flunil with other serotonergic agents can cause serotonin syndrome (tremor, hyperreflexia, clonus, hyperthermia, agitation). Avoid concurrent: MAOIs (14-day washout each direction; fluoxetine needs 5 weeks), tramadol, pethidine, dextromethorphan, linezolid, methylene blue, St John’s wort, MDMA. Triptan + SSRI is generally tolerated for migraine \u2014 the absolute risk is low.<\/p>\n<\/div>\n

Vanliga biverkningar<\/h2>\n