{"id":57466,"date":"2024-02-27T17:45:32","date_gmt":"2024-02-27T17:45:32","guid":{"rendered":"https:\/\/medsname.com\/grisovin-fp\/"},"modified":"2026-04-30T10:24:26","modified_gmt":"2026-04-30T10:24:26","slug":"grisovin-fp","status":"publish","type":"product","link":"https:\/\/medsbase.com\/sv\/product\/grisovin-fp\/","title":{"rendered":"Grisovin FP"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 20px;margin:18px 0;border-radius:6px;\">\n<h3 style=\"margin-top:0;\">\ud83d\udca1 Snabbt svar<\/h3>\n<p style=\"margin-bottom:0;\">Grisovin FP is griseofulvin 125 mg \/ 250 mg \/ 500 mg \u2014 an older oral antifungal used mainly for <strong>tinea capitis (scalp ringworm) in children<\/strong>, especially when the cause is Microsporum canis (terbinafine works less well on this organism). Active only against dermatophytes (Trichophyton, Epidermophyton, Microsporum); inactive against Candida, Malassezia, moulds. Long course required (6\u20138 weeks for tinea capitis, 6\u201312 months for onychomycosis). Mostly displaced by terbinafine and itraconazole for adult dermatophyte infections, but still relevant in paediatrics.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f5f5f5;border:1px solid #e1e1e1;padding:18px 22px;margin:24px 0;border-radius:8px;display:flex;flex-wrap:wrap;justify-content:space-around;gap:16px;align-items:center;font-size:0.95em;\">\n<div style=\"text-align:center;flex:1;min-width:140px;\">\ud83c\udfed<br \/><strong>WHO-GMP<\/strong><br \/>certifierad tillverkare<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Varje best\u00e4llning omfattas av v\u00e5r <a href=\"https:\/\/medsbase.com\/sv\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 om din f\u00f6rs\u00e4ndelse inte anl\u00e4nder inom 20 arbetsdagar, skickar vi om den.<\/p>\n<h3>Varf\u00f6r best\u00e4lla fr\u00e5n MedsBase<\/h3>\n<p>V\u00e5ra generiska l\u00e4kemedel kommer fr\u00e5n WHO-GMP-certifierade tillverkare och skickas v\u00e4rldsvidt i diskreta, enkla f\u00f6rpackningar \u2014 inget l\u00e4kemedelsnamn p\u00e5 f\u00f6rs\u00e4ndelsens utsida. Kortbetalningar hanteras via en reglerad betalningsprocessor (kontoutdrag visar en reglerad kortbetalningsprocessor \u2014 aldrig \u201cMedsBase\u201d eller n\u00e5got l\u00e4kemedelsnamn). Krypto och SEPA-bank\u00f6verf\u00f6ring accepteras ocks\u00e5. Varje best\u00e4llning backas upp av v\u00e5r Reshipment Assurance Policy.<\/p>\n<div style=\"text-align:center;flex:1;min-width:140px;\">\ud83d\udce6<br \/><strong>Diskret f\u00f6rpackning<\/strong><br \/>vanligt kuvert<\/div>\n<div style=\"text-align:center;flex:1;min-width:140px;\">\ud83c\udf0d<br \/><strong>V\u00e4rldsvid leverans<\/strong><br \/>till de flesta l\u00e4nder<\/div>\n<div style=\"text-align:center;flex:1;min-width:140px;\">\u2b50<br \/><strong>1 400+ kunder<\/strong><br \/><a href=\"https:\/\/medsbase.com\/sv\/reviews\/\">l\u00e4s recensioner<\/a><\/div>\n<\/div>\n<h2>\ud83d\udd12 Why order Grisovin FP from MedsBase<\/h2>\n<ul>\n<li><strong>WHO-GMP-certifierad tillverkare<\/strong> \u2014 h\u00e4mtad fr\u00e5n en reglerad anl\u00e4ggning, f\u00e4rdigf\u00f6rpackad med batchnummer och utg\u00e5ngsdatum.<\/li>\n<li><strong>Diskret f\u00f6rpackning<\/strong> \u2014 vanligt kuvert, inget l\u00e4kemedelsnamn p\u00e5 utsidan.<\/li>\n<li><strong>V\u00e4rldsvid leverans<\/strong> till de flesta l\u00e4nder med <a href=\"https:\/\/medsbase.com\/sv\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance<\/a>.<\/li>\n<li><strong>Lojalitetspo\u00e4ng<\/strong> \u2014 1 po\u00e4ng per $1 spenderad (exkluderar peptider\/frakt); 100 po\u00e4ng = $5 rabatt p\u00e5 din n\u00e4sta order.<\/li>\n<\/ul>\n<h2 id=\"uses\">Anv\u00e4ndningsomr\u00e5den &amp; indikationer<\/h2>\n<p>Grisovin FP (griseofulvin 125 mg \/ 250 mg \/ 500 mg, GSK) is one of the oldest oral antifungal agents. It binds to fungal microtubules, disrupting mitosis and inhibiting hyphal growth. Modern practice has largely replaced it with terbinafine and itraconazole for adults \u2014 but it remains relevant when:<\/p>\n<ul>\n<li>Treating tinea capitis caused by <strong>Microsporum<\/strong> (terbinafine has lower cure rates against Microsporum than against Trichophyton).<\/li>\n<li>Treating tinea capitis in children \u2014 long-established paediatric experience and safety data.<\/li>\n<li>Newer oral antifungals are unavailable, contraindicated, or unaffordable.<\/li>\n<\/ul>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:0.95em;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">Indikation<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">Typiskt behandlingsschema<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Tinea capitis \u2014 children<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">10\u201320 mg\/kg\/day microsize (or 5\u201310 mg\/kg ultramicrosize) \u00d7 6\u20138 weeks<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Tinea capitis \u2014 adults<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">500 mg\/day microsize \u00d7 4\u20136 weeks<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Tinea corporis \/ cruris \/ pedis (refractory)<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">500 mg\/day microsize \u00d7 2\u20136 weeks<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Onychomycosis \u2014 fingernail (largely abandoned)<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">500\u20131000 mg\/day microsize \u00d7 4\u20136 months<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Onychomycosis \u2014 toenail (largely abandoned)<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">500\u20131000 mg\/day microsize \u00d7 9\u201312 months<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"how-to-take\">Hur man tar<\/h2>\n<ul>\n<li>Take with a fatty meal \u2014 fat increases griseofulvin absorption ~2-fold.<\/li>\n<li>For children, the tablet can be crushed into food or yogurt if a paediatric oral suspension is unavailable.<\/li>\n<li>Complete the full course \u2014 symptomatic improvement comes within 1\u20132 weeks but stopping early causes relapse.<\/li>\n<\/ul>\n<h2 id=\"mechanism\">Hur det fungerar<\/h2>\n<p>Griseofulvin binds to fungal microtubules (specifically, \u03b2-tubulin) and disrupts mitotic spindle formation. The result is impaired hyphal growth. The drug is incorporated into newly-synthesised keratin in the hair, skin, and nail \u2014 meaning protected new growth replaces fungus-infected old keratin as it sheds. This is why long courses are required, especially for nail (which grows slowly).<\/p>\n<h2 id=\"side-effects\">Biverkningar<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:0.95em;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">Frekvens<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">Effekter<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Vanliga<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Headache (often early in therapy, often resolves), nausea, abdominal pain, photosensitivity, urticaria, dizziness<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Ovanliga<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Mild LFT rise, leukopenia, peripheral neuritis, taste disturbance, insomnia<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">S\u00e4llsynta men allvarliga<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Severe hepatitis (rare), Stevens-Johnson syndrome, lupus exacerbation, agranulocytosis, photosensitive rash that can resemble erythema multiforme<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"interactions\">L\u00e4kemedelsinteraktioner<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:0.95em;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">L\u00e4kemedel<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">Effekt<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">\u00c5tg\u00e4rd<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Warfarin<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\"><strong>INR falls<\/strong> (griseofulvin induces metabolism)<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Monitor INR; increase warfarin dose<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Combined oral contraceptive pill<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\"><strong>Reduced contraceptive efficacy<\/strong> (CYP induction; ethinylestradiol metabolism)<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Use additional barrier contraception during therapy and for 1 month after<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Phenobarbital<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Reduces griseofulvin levels<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Increase griseofulvin dose 50%<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Ciclosporin<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Levels fall<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Monitor; increase ciclosporin<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Alkohol<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Disulfiram-like flushing reaction (rare)<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Limit alcohol<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"contraindications\">Kontraindikationer<\/h2>\n<ul>\n<li>Severe liver disease, porphyria.<\/li>\n<li>Pregnancy (teratogenic in animals).<\/li>\n<li>Hypersensitivity to griseofulvin.<\/li>\n<li>Systemic lupus erythematosus (can precipitate flares).<\/li>\n<\/ul>\n<h2 id=\"pregnancy\">Graviditet &amp; amning<\/h2>\n<p>Griseofulvin is contraindicated in pregnancy. Effective contraception is required during therapy <strong>and for 1 month after the last dose<\/strong> (washout period). Men: limited data suggest sperm quality may be temporarily reduced \u2014 many guidelines recommend avoiding conception for 6 months after a course in men too, though the evidence base is weaker. Excretion in breast milk is unclear \u2014 alternatives are preferred.<\/p>\n<h2 id=\"faqs\">Vanliga fr\u00e5gor<\/h2>\n<h3>When is griseofulvin still preferred over terbinafine?<\/h3>\n<p>For tinea capitis caused by Microsporum canis (typically picked up from cats \/ dogs). Terbinafine has 60\u201370% cure rates for Microsporum versus &gt; 90% for Trichophyton; griseofulvin has 80\u201390% cure rates for Microsporum. The cause is determined by fungal culture or PCR. Pre-school children with kitten exposure \u2014 Microsporum is a common cause.<\/p>\n<h3>My child has scalp ringworm \u2014 what should I expect?<\/h3>\n<p>6\u20138 weeks of daily oral griseofulvin (or 4 weeks oral terbinafine if Trichophyton). Plus medicated shampoo (selenium sulphide or ketoconazole) twice weekly to reduce shedding to others. Don&#8217;t share hairbrushes \/ hats. School policy: most schools allow attendance once treatment is started.<\/p>\n<h3>Why does griseofulvin reduce the contraceptive pill?<\/h3>\n<p>Griseofulvin induces hepatic CYP enzymes that metabolise oestrogen and progestogen. Ethinylestradiol levels can fall enough to allow ovulation. Use additional barrier contraception during the course and for 1 month after the last dose. This warning applies to combined pills, mini-pills, contraceptive patch, and vaginal ring; the levonorgestrel IUS and copper IUD are unaffected.<\/p>\n<h3>Why a fatty meal?<\/h3>\n<p>Griseofulvin is poorly water-soluble. Taken with a high-fat meal (e.g. eggs, full-fat yogurt, peanut butter on toast), bioavailability roughly doubles compared to fasting. For paediatric dosing, mixing the crushed tablet into yogurt or peanut butter is both an absorption strategy and a palatability strategy.<\/p>\n<h3>Is Grisovin FP the same as Fulcin \/ Grisactin?<\/h3>\n<p>Yes \u2014 Fulcin and Grisactin are older brand names of griseofulvin. Grisovin FP contains the same active ingredient, manufactured by GSK under WHO-GMP. Bioequivalent.<\/p>\n<h3>Why am I getting a rash on my arms in the sun?<\/h3>\n<p>Griseofulvin is photosensitising. UV exposure during therapy can produce an itchy rash on sun-exposed skin. Use SPF 30+ broad-spectrum sunscreen, long sleeves outdoors, and avoid sunbeds during the course.<\/p>\n<h3>Can my child play sport with tinea capitis?<\/h3>\n<p>Yes \u2014 once treatment is started. Avoid sharing helmets \/ caps \/ hairbrushes; wash bedding hot. Most school and sports authorities allow return to activity 24\u201348 hours after starting oral antifungal.<\/p>\n<h3>What if my tinea pedis or onychomycosis hasn&#8217;t cleared after 12 weeks of griseofulvin?<\/h3>\n<p>Switch to terbinafine or itraconazole \u2014 both have higher cure rates for adult-onset dermatophyte nail and skin infections. Recheck the fungal diagnosis with a clipping for microscopy \/ culture before changing \u2014 the original diagnosis may have been wrong.<\/p>\n<h3>Is it safe to drink alcohol on griseofulvin?<\/h3>\n<p>A rare disulfiram-like reaction (flushing, tachycardia, nausea) has been reported. Most patients tolerate moderate alcohol without issue. Avoid heavy drinking during the course.<\/p>\n<h3>Why is the course so long for nails?<\/h3>\n<p>Griseofulvin only protects newly-formed keratin \u2014 it does not eradicate fungus from existing infected nail. The nail has to grow out from the cuticle. Toenails grow ~1.5 mm per month, so a fully grown-out toenail takes ~9 months. Modern practice prefers terbinafine or itraconazole for nail because they concentrate in the existing nail and shorten the active treatment phase.<\/p>\n<h2 id=\"storage\">F\u00f6rvaring<\/h2>\n<p>Store tablets at 15\u201325 \u00b0C, away from light and moisture. Keep out of reach of children. Do not use after expiry.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2>Andra antimykotiska l\u00e4kemedel som kan vara av intresse<\/h2>\n<p>If Grisovin FP is unavailable, here are alternatives \u2014 same molecule from a different manufacturer, plus first-line modern alternatives where griseofulvin is no longer preferred.<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/sv\/zimig\/\"><strong>Zimig (terbinafin 250 mg)<\/strong><\/a> \u2014 First-line for adult dermatophyte tinea \/ onychomycosis.<\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/sporanox-capsule\/\"><strong>Sporanox (itraconazol 100 mg)<\/strong><\/a> \u2014 Onychomycosis pulse therapy alternative.<\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/clocip\/\"><strong>Clocip (klotrimazol 1% kr\u00e4m)<\/strong><\/a> \u2014 Topical for skin tinea + Candida; pregnancy-safe.<\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/keto-cream\/\"><strong>Keto Cream (ketokonazol 2%)<\/strong><\/a> \u2014 Topical for tinea + seborrhoeic dermatitis.<\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/loceryl-nail-liq\/\"><strong>Loceryl (amorolfine 5%)<\/strong><\/a> \u2014 Topical lacquer for mild distal nail infection.<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:12px 18px;margin:24px 0;font-size:0.95em;\"><strong>Medicinsk ansvarsfriskrivning.<\/strong> Denna sida \u00e4r produktinformation f\u00f6r vuxna som best\u00e4ller antimykotiska l\u00e4kemedel f\u00f6r eget bruk. Det \u00e4r inte en ers\u00e4ttning f\u00f6r individuell medicinsk r\u00e5dgivning. Diskutera r\u00e4tt antimykotikum, dos och behandlingsl\u00e4ngd med en kvalificerad kliniker \u2014 s\u00e4rskilt om du har leversjukdom, \u00e4r gravid eller ammar, tar warfarin, tar statin, tar immunosuppressiva l\u00e4kemedel eller har en svampinfektion i nageln som kan vara en annan diagnos (psoriasis, lichen planus, trauma).<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u2705 Behandlar svampinfektioner<br \/>\n\u2705 Inhibits fungal growth<br \/>\n\u2705 Lindrar kl\u00e5da<br \/>\n\u2705 Eliminates ringworm<br \/>\n\u2705 Fr\u00e4mjar hudl\u00e4kning<\/p>\n<p>Grisovin FP contains Griseofulvin.<\/p>","protected":false},"featured_media":57467,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3501,3141,3504,3342],"product_tag":[4272,4310],"class_list":{"0":"post-57466","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-fungal","7":"product_cat-category-overview","8":"product_cat-fungal-infection-treatment","9":"product_cat-general-health","10":"product_tag-griseofulvin","11":"product_tag-grisovin-fp","13":"first","14":"instock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/product\/57466","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/comments?post=57466"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/media\/57467"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/media?parent=57466"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/product_brand?post=57466"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/product_cat?post=57466"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/product_tag?post=57466"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}