{"id":57949,"date":"2024-02-27T18:09:12","date_gmt":"2024-02-27T18:09:12","guid":{"rendered":"https:\/\/medsname.com\/atarise\/"},"modified":"2026-04-30T10:24:19","modified_gmt":"2026-04-30T10:24:19","slug":"atarise","status":"publish","type":"product","link":"https:\/\/medsbase.com\/sv\/product\/atarise\/","title":{"rendered":"Atarise"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"background:#fff8d6;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<h3 style=\"margin-top:0;\">\u26a1 Snabbt svar<\/h3>\n<p style=\"margin-bottom:0;\">Atarise (Hydroxyzine 10 \/ 25 mg) is a sedating first-generation antihistamine and centrally-acting anxiolytic. Used for short-term anxiety, pre-procedural sedation, allergic pruritus and urticaria, and as an antiemetic. Non-addictive \u2014 useful when benzodiazepines are inappropriate.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Vad du f\u00e5r med MedsBase:<\/strong> WHO-GMP-certifierad tillverkare \u00b7 Diskret f\u00f6rpackning \u00b7 V\u00e4rldsvid leverans \u00b7 1 400+ verifierade <a href=\"https:\/\/medsbase.com\/sv\/reviews\/\">kundrecensioner<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Varje best\u00e4llning omfattas av v\u00e5r <a href=\"https:\/\/medsbase.com\/sv\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 om din f\u00f6rs\u00e4ndelse inte anl\u00e4nder inom 20 arbetsdagar, skickar vi om den.<\/p>\n<h3>Varf\u00f6r best\u00e4lla fr\u00e5n MedsBase<\/h3>\n<p>Atarise at MedsBase is supplied directly from a WHO-GMP certified manufacturer in plain, discreet packaging. Every order is covered by our <a href=\"https:\/\/medsbase.com\/sv\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance Policy<\/a> \u2014 20 arbetsdagar leveranstid eller vi skickar om utan extra kostnad \u2014 och kvalificerar sig f\u00f6r v\u00e5rt <a href=\"https:\/\/medsbase.com\/sv\/loyalty-points\/\">kundlojalitetsprogram<\/a>. V\u00e4rldsomsp\u00e4nnande leverans \u00e4r tillg\u00e4nglig till de flesta destinationer.<\/p>\n<h2>What Atarise is and how it works<\/h2>\n<p>Atarise is a 10 \/ 25 mg hydroxyzine tablet supplied by Sun Pharma. Hydroxyzine is a piperazine first-generation antihistamine with strong central H1 antagonism, weak 5-HT2A antagonism, and modest anticholinergic activity. The H1 component crosses the blood-brain barrier well and is the basis for its sedating and anxiolytic effect.<\/p>\n<p>Hydroxyzine is one of the few non-benzodiazepine, non-barbiturate options for true PRN anxiety relief \u2014 onset within 30\u201360 minutes, duration 4\u20136 hours.<\/p>\n<h2>Indikationer och dosering<\/h2>\n<table>\n<thead>\n<tr>\n<th>Indikation<\/th>\n<th>Vuxendos<\/th>\n<th>Anteckningar<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Acute anxiety \/ agitation<\/td>\n<td>25\u2013100 mg PO\/IM, may repeat q6h<\/td>\n<td>Max 400 mg\/day<\/td>\n<\/tr>\n<tr>\n<td>Pruritus \/ urticaria<\/td>\n<td>25 mg TID\u2013QID<\/td>\n<td>Max 100 mg QID<\/td>\n<\/tr>\n<tr>\n<td>Pre-operative sedation<\/td>\n<td>50\u2013100 mg 1 hour pre-op<\/td>\n<td>\u2014<\/td>\n<\/tr>\n<tr>\n<td>Antiemetic<\/td>\n<td>25\u2013100 mg IM<\/td>\n<td>Adults only<\/td>\n<\/tr>\n<tr>\n<td>Insomnia (off-label)<\/td>\n<td>25\u201350 mg HS<\/td>\n<td>Short-term only<\/td>\n<\/tr>\n<tr>\n<td>Paediatric pruritus \/ sedation<\/td>\n<td>0.5\u20131 mg\/kg\/dose q6h<\/td>\n<td>\u2014<\/td>\n<\/tr>\n<tr>\n<td>Older adults (any indication)<\/td>\n<td>start 10\u201325 mg<\/td>\n<td>QT and falls risk<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Viktiga s\u00e4kerhets\u00f6verv\u00e4ganden<\/h2>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>QT prolongation \u2014 2015 EMA restriction<\/strong><\/p>\n<p style=\"margin-bottom:0;\">Hydroxyzine prolongs QT in a dose-dependent manner. The EMA restricted dosing in 2015: <strong>maximum 100 mg\/day in adults, 50 mg\/day in older adults, and 2 mg\/kg\/day in children<\/strong>. Avoid in known QT prolongation, hypokalaemia\/hypomagnesaemia, recent MI, uncompensated heart failure, and concurrent QT-prolonging drugs (azoles, macrolides, fluoroquinolones, methadone, ondansetron, antipsychotics). Pre-treatment ECG advised in older adults.<\/p>\n<\/div>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>Antikolinerg belastning<\/strong><\/p>\n<p style=\"margin-bottom:0;\">Hydroxyzine has meaningful anticholinergic activity \u2014 particularly relevant in older adults (Beers Criteria potentially inappropriate medication). Avoid in narrow-angle glaucoma, BPH with retention, dementia, severe constipation. The American Geriatrics Society discourages first-generation antihistamines as PRN agents in older adults.<\/p>\n<\/div>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>Sedation and driving<\/strong><\/p>\n<p style=\"margin-bottom:0;\">Single-dose sedation can persist 6+ hours; avoid driving and operating machinery until tolerability is known. Particularly problematic in opioid-naive surgical patients on the day of discharge.<\/p>\n<\/div>\n<h2>Vanliga biverkningar<\/h2>\n<ul>\n<li><strong>Sedation \/ drowsiness:<\/strong> universal at therapeutic doses.<\/li>\n<li><strong>Antikolinerg:<\/strong> dry mouth, constipation, urinary hesitancy, blurred vision.<\/li>\n<li><strong>QT:<\/strong> dose-dependent prolongation.<\/li>\n<li><strong>CNS:<\/strong> dizziness, ataxia, paradoxical agitation in older adults and children.<\/li>\n<li><strong>Uttr\u00e5dning:<\/strong> none \u2014 non-addictive.<\/li>\n<\/ul>\n<h2>L\u00e4kemedelsinteraktioner<\/h2>\n<ul>\n<li><strong>Andra QT-f\u00f6rl\u00e4ngande l\u00e4kemedel<\/strong> \u2014 additive risk.<\/li>\n<li><strong>CNS-depressiva medel<\/strong> (alcohol, benzodiazepines, opioids, Z-drugs) \u2014 additive sedation.<\/li>\n<li><strong>Antikolinergika<\/strong> \u2014 additiv belastning.<\/li>\n<li><strong>MAO-h\u00e4mmare<\/strong> \u2014 additive anticholinergic and CNS depressant effects.<\/li>\n<\/ul>\n<h2>Graviditet, amning, pediatrisk anv\u00e4ndning<\/h2>\n<p>Pregnancy: avoid in early pregnancy; safer alternatives exist. Breastfeeding: passes into milk and can sedate the infant; usually avoided. Paediatric: dosing per kg, watch for paradoxical excitation (5\u201310% of children).<\/p>\n<h2>F\u00f6rvaring<\/h2>\n<p>F\u00f6rvara vid 15\u201330 \u00b0C i originalf\u00f6rpackning.<\/p>\n<h2 id=\"faqs\">Vanliga fr\u00e5gor<\/h2>\n<h3>How is Atarise different from a benzodiazepine?<\/h3>\n<p>Hydroxyzine acts on H1 histamine receptors, not GABA-A. The clinical translation: similar acute sedation, similar anxiolysis, but no abuse potential, no dependence, no respiratory depression with overdose, no withdrawal syndrome. Hydroxyzine has a lower ceiling effect \u2014 at therapeutic doses it doesn&rsquo;t reach the depth of acute relief produced by alprazolam or lorazepam.<\/p>\n<h3>Can I take Atarise as needed for anxiety?<\/h3>\n<p>Yes \u2014 onset is 30\u201360 minutes, duration 4\u20136 hours, and no addiction risk. Atarise is one of the better PRN options when benzodiazepines are inappropriate (substance-use history, pregnancy, occupational exposure to controlled-substance testing, primary-care setting reluctant to prescribe BZDs).<\/p>\n<h3>Will Atarise make me drowsy the next day?<\/h3>\n<p>Sometimes \u2014 particularly with bedtime doses 50 mg+. Older adults are most susceptible. Lower doses (25 mg) usually clear by morning.<\/p>\n<h3>Is Atarise safe in older adults?<\/h3>\n<p>Hydroxyzine is on the Beers Criteria list of potentially inappropriate medications in older adults because of anticholinergic burden, fall risk, and QT signal. Use is not absolutely prohibited but should be cautious, time-limited, and at lower doses.<\/p>\n<h3>Why does Atarise have a QT warning?<\/h3>\n<p>Like many sedating antihistamines, hydroxyzine prolongs the QT interval in a dose-dependent way. At occasional doses in young patients with normal ECGs the risk is negligible; at high daily doses or in older patients with cardiovascular disease the risk is clinically meaningful. The EMA dose caps reflect this.<\/p>\n<h3>Can Atarise be used long-term?<\/h3>\n<p>Daily use beyond a few weeks is uncommon \u2014 tolerance to the sedative effect develops, and the anticholinergic burden accumulates. For chronic GAD, an SSRI\/SNRI or buspirone is preferred. Atarise works best as PRN or short-term bridge.<\/p>\n<h3>Can I drive on Atarise?<\/h3>\n<p>Avoid driving for at least 6\u20138 hours after a dose, particularly with the first few doses. Most patients on stable low-dose regimens drive normally \u2014 but the legal definition of impairment varies by jurisdiction.<\/p>\n<h3>Can Atarise be used in pregnancy?<\/h3>\n<p>First-trimester use is generally avoided because of theoretical concerns; later in pregnancy, hydroxyzine has been used for nausea-vomiting and pruritus with reasonable safety. Discuss with your obstetrician.<\/p>\n<h3>Can children take Atarise?<\/h3>\n<p>Yes \u2014 hydroxyzine is one of the older agents in paediatric sedation and pruritus. Watch for paradoxical excitation (5\u201310% of children become more agitated rather than less).<\/p>\n<h3>Is Atarise addictive?<\/h3>\n<p>No \u2014 no euphoria, no compulsive use, no withdrawal, no tolerance to anxiolytic effect (sedation tolerance does develop somewhat with daily use).<\/p>\n<h2>Andra l\u00e4kemedel f\u00f6r psykisk h\u00e4lsa<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/sv\/busiron\/\">Busiron (Buspirone \u2014 non-sedating GAD)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/lexaheal\/\">Lexaheal (Escitalopram \u2014 f\u00f6rsta valet vid GAD)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/pexep\/\">Pexep (Paroxetine \u2014 f\u00f6rsta valet vid GAD)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/mirtaz\/\">Mirtaz (Mirtazapine \u2014 sedating antidepressant)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/fliban\/\">Fliban (Flibanserin \u2014 HSDD; female libido)<\/a><\/li>\n<\/ul>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:0.9em;\">\n<strong>Medicinsk ansvarsfriskrivning.<\/strong> Denna sida \u00e4r informativ och ers\u00e4tter inte individuell medicinsk r\u00e5dgivning. 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Om du eller n\u00e5gon du k\u00e4nner befinner sig i en suicidkris, kontakta omedelbart lokal akuthj\u00e4lp eller ring din lands sj\u00e4lvmordsf\u00f6rebyggande hj\u00e4lplinje (USA\/Kanada: 988; Storbritannien: Samaritans 116 123; internationell lista: <a href=\"https:\/\/findahelpline.com\/\" rel=\"nofollow noopener\" target=\"_blank\">findahelpline.com<\/a>).\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Atarise (Hydroxyzine HCl 10\/25 mg) \u2014 sedating first-generation antihistamine for PRN anxiety, pruritus, sedation. non-addictive PRN anxiolytic \u2014 onset 30\u201360 min.<\/p>","protected":false},"featured_media":57950,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3906],"product_tag":[4390,4391],"class_list":{"0":"post-57949","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-mental-health-and-psychiatric-medications","9":"product_tag-atarise","10":"product_tag-hydroxizine","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/product\/57949","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/comments?post=57949"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/media\/57950"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/media?parent=57949"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/product_brand?post=57949"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/product_cat?post=57949"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/product_tag?post=57949"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}